Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10903
Gene name Gene Name - the full gene name approved by the HGNC.	Myotubularin related protein 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MTMR11
Synonyms (NCBI Gene) Gene synonyms aliases	CRA
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q21.2

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miRTarBase ID	miRNA	Experiments
MIRT1163698	hsa-miR-320a	CLIP-seq
MIRT1163699	hsa-miR-320b	CLIP-seq
MIRT1163700	hsa-miR-320c	CLIP-seq
MIRT1163701	hsa-miR-320d	CLIP-seq
MIRT1163702	hsa-miR-3616-5p	CLIP-seq
MIRT1163703	hsa-miR-3647-5p	CLIP-seq
MIRT1163704	hsa-miR-4429	CLIP-seq
MIRT1163705	hsa-miR-4446-3p	CLIP-seq
MIRT1163706	hsa-miR-4656	CLIP-seq
MIRT1163707	hsa-miR-4795-5p	CLIP-seq
MIRT1163708	hsa-miR-573	CLIP-seq
MIRT1163709	hsa-miR-595	CLIP-seq
MIRT2047062	hsa-miR-105	CLIP-seq
MIRT2047063	hsa-miR-205	CLIP-seq
MIRT2047064	hsa-miR-3671	CLIP-seq
MIRT2047065	hsa-miR-607	CLIP-seq
MIRT2575021	hsa-miR-1248	CLIP-seq
MIRT2575022	hsa-miR-2467-5p	CLIP-seq
MIRT2575023	hsa-miR-3188	CLIP-seq
MIRT1163698	hsa-miR-320a	CLIP-seq
MIRT1163699	hsa-miR-320b	CLIP-seq
MIRT1163700	hsa-miR-320c	CLIP-seq
MIRT1163701	hsa-miR-320d	CLIP-seq
MIRT2575024	hsa-miR-3606	CLIP-seq
MIRT1163702	hsa-miR-3616-5p	CLIP-seq
MIRT1163703	hsa-miR-3647-5p	CLIP-seq
MIRT2575025	hsa-miR-3674	CLIP-seq
MIRT2575026	hsa-miR-3975	CLIP-seq
MIRT1163704	hsa-miR-4429	CLIP-seq
MIRT1163705	hsa-miR-4446-3p	CLIP-seq
MIRT2575027	hsa-miR-4649-3p	CLIP-seq
MIRT1163706	hsa-miR-4656	CLIP-seq
MIRT1163707	hsa-miR-4795-5p	CLIP-seq
MIRT2575028	hsa-miR-485-5p	CLIP-seq
MIRT2575029	hsa-miR-548p	CLIP-seq
MIRT1163708	hsa-miR-573	CLIP-seq
MIRT1163709	hsa-miR-595	CLIP-seq
MIRT2575030	hsa-miR-921	CLIP-seq
MIRT2575021	hsa-miR-1248	CLIP-seq
MIRT2685488	hsa-miR-2276	CLIP-seq
MIRT2575022	hsa-miR-2467-5p	CLIP-seq
MIRT2575023	hsa-miR-3188	CLIP-seq
MIRT1163698	hsa-miR-320a	CLIP-seq
MIRT1163699	hsa-miR-320b	CLIP-seq
MIRT1163700	hsa-miR-320c	CLIP-seq
MIRT1163701	hsa-miR-320d	CLIP-seq
MIRT2575024	hsa-miR-3606	CLIP-seq
MIRT1163702	hsa-miR-3616-5p	CLIP-seq
MIRT1163703	hsa-miR-3647-5p	CLIP-seq
MIRT2575025	hsa-miR-3674	CLIP-seq
MIRT2575026	hsa-miR-3975	CLIP-seq
MIRT1163704	hsa-miR-4429	CLIP-seq
MIRT1163705	hsa-miR-4446-3p	CLIP-seq
MIRT2685489	hsa-miR-451b	CLIP-seq
MIRT2575027	hsa-miR-4649-3p	CLIP-seq
MIRT1163706	hsa-miR-4656	CLIP-seq
MIRT2685490	hsa-miR-4696	CLIP-seq
MIRT1163707	hsa-miR-4795-5p	CLIP-seq
MIRT2575028	hsa-miR-485-5p	CLIP-seq
MIRT2575029	hsa-miR-548p	CLIP-seq
MIRT1163708	hsa-miR-573	CLIP-seq
MIRT1163709	hsa-miR-595	CLIP-seq
MIRT2575030	hsa-miR-921	CLIP-seq

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004438	Function	Phosphatidylinositol-3-phosphatase activity	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	16787938
GO:0016020	Component	Membrane	IBA	21873635
GO:0046856	Process	Phosphatidylinositol dephosphorylation	IBA	21873635
GO:0070062	Component	Extracellular exosome	HDA	18570454

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

A4FU01

Protein name

Myotubularin-related protein 11 (Cisplatin resistance-associated protein) (hCRA) (Inactive phosphatidylinositol 3-phosphatase 11)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06602	Myotub-related	169 → 318	Myotubularin-like phosphatase domain	Domain
PF06602	Myotub-related	302 → 483	Myotubularin-like phosphatase domain	Domain
PF12578	3-PAP	548 → 678	Myotubularin-associated protein	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in bone marrow, spleen and thymus. {ECO:0000269|PubMed:17498563}.

Sequence

MWWGGRGQSFNIAPQKEEPEMGSVQENRMPEPRSRQPSSCLASRCLPGEQILAWAPGVRK
GLEPELSGTLICTNFRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRP
GSLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLS
KAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRIL
DSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDV
VLVDTMDELPSLADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDI
SVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLT
RLGGTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPW
ERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHC
PDSWLPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSE
SLADQEWGLPSHWGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQD
ELSHLQELLRKWTPRISPEDHSKKRDPHTILNPTEIAGILKGRAEGDLG

Sequence length

709

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	29059683

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Evidence	Source
Unknown
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients	GWAS, CBGDA
Carpal Tunnel Syndrome	Carpal Tunnel Syndrome		GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining
Aortic Aneurysm Abdominal	Associate	25993293
Breast Neoplasms	Associate	20413845
Epilepsy	Associate	11879359
FOR heavy chain disease protein human	Associate	4100047
Neoplasms	Associate	20413845

MTMR11 (myotubularin related protein 11)