Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10803
Gene name Gene Name - the full gene name approved by the HGNC.	C-C motif chemokine receptor 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CCR9
Synonyms (NCBI Gene) Gene synonyms aliases	CC-CKR-9, CDw199, GPR-9-6, GPR28
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p21.31
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inf

Show/Hide all(42)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018889	hsa-miR-335-5p	Microarray	18185580
MIRT020973	hsa-miR-155-5p	Proteomics	19193853
MIRT021275	hsa-miR-146a-5p	Microarray	18057241
MIRT873296	hsa-miR-1252	CLIP-seq
MIRT873297	hsa-miR-154	CLIP-seq
MIRT873298	hsa-miR-155	CLIP-seq
MIRT873299	hsa-miR-25	CLIP-seq
MIRT873300	hsa-miR-302f	CLIP-seq
MIRT873301	hsa-miR-31	CLIP-seq
MIRT873302	hsa-miR-3128	CLIP-seq
MIRT873303	hsa-miR-32	CLIP-seq
MIRT873304	hsa-miR-362-5p	CLIP-seq
MIRT873305	hsa-miR-363	CLIP-seq
MIRT873306	hsa-miR-367	CLIP-seq
MIRT873307	hsa-miR-3977	CLIP-seq
MIRT873308	hsa-miR-4420	CLIP-seq
MIRT873309	hsa-miR-4428	CLIP-seq
MIRT873310	hsa-miR-4685-5p	CLIP-seq
MIRT873311	hsa-miR-4696	CLIP-seq
MIRT873312	hsa-miR-4773	CLIP-seq
MIRT873313	hsa-miR-500a	CLIP-seq
MIRT873314	hsa-miR-500b	CLIP-seq
MIRT873315	hsa-miR-548aa	CLIP-seq
MIRT873316	hsa-miR-603	CLIP-seq
MIRT873317	hsa-miR-92a	CLIP-seq
MIRT873318	hsa-miR-92b	CLIP-seq
MIRT1959113	hsa-miR-1227	CLIP-seq
MIRT1959114	hsa-miR-421	CLIP-seq
MIRT1959115	hsa-miR-4252	CLIP-seq
MIRT1959116	hsa-miR-4709-5p	CLIP-seq
MIRT2196044	hsa-miR-15a	CLIP-seq
MIRT2196045	hsa-miR-15b	CLIP-seq
MIRT2196046	hsa-miR-16	CLIP-seq
MIRT2196047	hsa-miR-195	CLIP-seq
MIRT2196048	hsa-miR-3137	CLIP-seq
MIRT2196049	hsa-miR-424	CLIP-seq
MIRT2196050	hsa-miR-4524	CLIP-seq
MIRT2196051	hsa-miR-4676-5p	CLIP-seq
MIRT2196052	hsa-miR-497	CLIP-seq
MIRT2196053	hsa-miR-503	CLIP-seq
MIRT2196054	hsa-miR-575	CLIP-seq
MIRT2196055	hsa-miR-646	CLIP-seq

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002305	Process	CD8-positive, gamma-delta intraepithelial T cell differentiation	IEA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004950	Function	Chemokine receptor activity	IEA
GO:0004950	Function	Chemokine receptor activity	TAS	10229797
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	10229797
GO:0006935	Process	Chemotaxis	IEA
GO:0006935	Process	Chemotaxis	IEA
GO:0006935	Process	Chemotaxis	TAS	10640743
GO:0006955	Process	Immune response	IBA
GO:0006955	Process	Immune response	IEA
GO:0006955	Process	Immune response	TAS	10229797
GO:0006968	Process	Cellular defense response	TAS	10544196
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS	10544196
GO:0007204	Process	Positive regulation of cytosolic calcium ion concentration	IBA
GO:0007204	Process	Positive regulation of cytosolic calcium ion concentration	TAS	10229797
GO:0009897	Component	External side of plasma membrane	IBA
GO:0009986	Component	Cell surface	IDA	18308860
GO:0016020	Component	Membrane	IEA
GO:0016493	Function	C-C chemokine receptor activity	IBA
GO:0016493	Function	C-C chemokine receptor activity	IEA
GO:0019722	Process	Calcium-mediated signaling	IBA
GO:0019957	Function	C-C chemokine binding	IBA
GO:0060326	Process	Cell chemotaxis	IBA
GO:0070098	Process	Chemokine-mediated signaling pathway	IEA

MIM	HGNC	e!Ensembl
604738	1610	ENSG00000173585

Protein

UniProt ID

P51686

Protein name

C-C chemokine receptor type 9 (C-C CKR-9) (CC-CKR-9) (CCR-9) (G-protein coupled receptor 28) (GPR-9-6) (CD antigen CDw199)

Protein function

Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. ; (Microbial infection) Alternative coreceptor with CD4

PDB

5LWE

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	65 → 317	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in the thymus and low in lymph nodes and spleen. {ECO:0000269|PubMed:10229797, ECO:0000269|PubMed:10640743}.

Sequence

MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
ETTSGALSL

Sequence length

369

Interactions

View interactions

	KEGG		Reactome
	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Intestinal immune network for IgA production		Chemokine receptors bind chemokines G alpha (i) signalling events

CCR9 (C-C motif chemokine receptor 9)