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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q14587 |
| Protein name |
Zinc finger protein 268 (Zinc finger protein HZF3) |
| Protein function |
[Isoform 1]: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression.; [Isoform 2]: Contributes to cervical carcinogenesis in |
| PDB |
2EL4
, 2EL5
, 2EL6
, 2EM1
, 2EMV
, 2EMW
, 2EMX
, 2EMY
, 2EN0
, 2EN6
, 2EN7
, 2EOF
, 2EOG
, 2EOI
, 2EOJ
, 2EOK
, 2EOL
, 2EOP
, 2EPV
, 2EPW
, 2EPY
, 2YTF
, 2YTQ
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| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
| PF01352 |
KRAB |
80 → 121 |
KRAB box |
Family |
| PF00096 |
zf-C2H2 |
304 → 326 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
332 → 354 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
360 → 382 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
388 → 410 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
416 → 438 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
444 → 466 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
500 → 522 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
528 → 550 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
556 → 578 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
584 → 606 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
612 → 634 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
640 → 662 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
668 → 690 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
696 → 718 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
724 → 746 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
752 → 774 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
780 → 802 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
808 → 830 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
864 → 886 |
Zinc finger, C2H2 type |
Domain |
| PF00096 |
zf-C2H2 |
892 → 914 |
Zinc finger, C2H2 type |
Domain |
|
| Tissue specificity |
TISSUE SPECIFICITY: Overexpressed in ovarian cancer tissues compared to normal ovarian tissues. Isoform 1 and isoform 2 are expressed in squamous epithelium tissues. Isoform 2 is overexpressed in squamous cervical cancer (at protein level). Expressed in b |
| Sequence |
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| Sequence length |
947 |
| Interactions |
View interactions |