NUP50 (nucleoporin 50)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10762 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Nucleoporin 50 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NUP50 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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NPAP60, NPAP60L |
Chromosome
Chromosome number
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22 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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22q13.31 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex i |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q9UKX7 | |||||||||||||||
Protein name | Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50) | |||||||||||||||
Protein function | Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (P | |||||||||||||||
PDB | 2EC1 , 3TJ3 , 7MO0 | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver. | |||||||||||||||
Sequence |
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Sequence length | 468 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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