Gene Gene information from NCBI Gene database.
Entrez ID 10672
Gene name G protein subunit alpha 13
Gene symbol GNA13
Synonyms (NCBI Gene)
G13HG1N
Chromosome 17
Chromosome location 17q24.1
miRNA miRNA information provided by mirtarbase database.
1151
miRTarBase ID miRNA Experiments Reference
MIRT001546 hsa-miR-155-5p pSILAC 18668040
MIRT001546 hsa-miR-155-5p Proteomics;Other 18668040
MIRT023441 hsa-miR-30b-5p Sequencing 20371350
MIRT023990 hsa-miR-1-3p Proteomics;Microarray 18668037
MIRT028679 hsa-miR-30a-5p Proteomics 18668040
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
57
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0001525 Process Angiogenesis IEA
GO:0001569 Process Branching involved in blood vessel morphogenesis IEA
GO:0001664 Function G protein-coupled receptor binding IEA
GO:0001701 Process In utero embryonic development IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604406 4381 ENSG00000120063
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q14344
Protein name Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13)
Protein function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16705036, PubMed:16787920, PubMed:27084452). Activates effector molecule RhoA by bindi
PDB 7SF7 , 7SF8 , 7T6B , 7YDH , 8H8J , 8KGG , 8ZX4 , 8ZX5 , 9GE2 , 9GE3 , 9IY8 , 9IZH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00503 G-alpha 28 366 G-protein alpha subunit Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in testis, including in Leydig cells and in the seminiferous epithelium, in differentiating cells from the spermatogonia to mature spermatozoa stages and round spermatids (at protein level). Expressed in 99.2% of spermatozoa
Sequence
Sequence length 377
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Hormone signaling
Vascular smooth muscle contraction
Apelin signaling pathway
Platelet activation
Long-term depression
Regulation of actin cytoskeleton
Parathyroid hormone synthesis, secretion and action
Pathogenic Escherichia coli infection
Human cytomegalovirus infection
Pathways in cancer
  NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
Thrombin signalling through proteinase activated receptors (PARs)