Gene Gene information from NCBI Gene database.
Entrez ID 10640
Gene name Exocyst complex component 5
Gene symbol EXOC5
Synonyms (NCBI Gene)
HSEC10PRO1912SEC10SEC10L1SEC10P
Chromosome 14
Chromosome location 14q22.3
Summary The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and f
miRNA miRNA information provided by mirtarbase database.
876
miRTarBase ID miRNA Experiments Reference
MIRT016216 hsa-miR-590-3p Sequencing 20371350
MIRT021840 hsa-miR-132-3p Microarray 17612493
MIRT027217 hsa-miR-103a-3p Sequencing 20371350
MIRT028361 hsa-miR-32-5p Sequencing 20371350
MIRT031031 hsa-miR-21-5p Microarray 18591254
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
GO ID Ontology Definition Evidence Reference
GO:0000145 Component Exocyst IBA
GO:0000145 Component Exocyst NAS 22420621
GO:0000281 Process Mitotic cytokinesis NAS 22420621
GO:0001736 Process Establishment of planar polarity IEA
GO:0005515 Function Protein binding IPI 21516116, 25416956, 25910212, 26871637, 27173435, 28514442, 31515488, 32296183, 32814053, 33961781
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604469 10696 ENSG00000070367
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O00471
Protein name Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10)
Protein function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07393 Sec10 89 707 Exocyst complex component Sec10 Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:9119050}.
Sequence
Sequence length 708
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Salmonella infection   Insulin processing
VxPx cargo-targeting to cilium
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Thymoma Uncertain significance rs780117264 RCV005931248