Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10611
Gene name Gene Name - the full gene name approved by the HGNC.	PDZ and LIM domain 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PDLIM5
Synonyms (NCBI Gene) Gene synonyms aliases	ENH, ENH1, L9, LIM
Chromosome Chromosome number	4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	4q22.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001527	hsa-miR-155-5p	pSILAC	18668040
MIRT001527	hsa-miR-155-5p	Western blot	20584899
MIRT032035	hsa-miR-16-5p	Proteomics	18668040
MIRT051014	hsa-miR-17-5p	CLASH	23622248
MIRT438719	hsa-miR-133a-3p	Luciferase reporter assay, qRT-PCR, Western blot	23968734
MIRT438719	hsa-miR-133a-3p	Luciferase reporter assay, qRT-PCR, Western blot	23968734
MIRT716416	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT716415	hsa-miR-513a-3p	HITS-CLIP	19536157
MIRT716414	hsa-miR-513c-3p	HITS-CLIP	19536157
MIRT716413	hsa-miR-205-3p	HITS-CLIP	19536157
MIRT716412	hsa-miR-4722-3p	HITS-CLIP	19536157
MIRT716411	hsa-miR-6727-3p	HITS-CLIP	19536157
MIRT716410	hsa-miR-6747-3p	HITS-CLIP	19536157
MIRT716409	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT716408	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT716407	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT716406	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT716405	hsa-miR-607	HITS-CLIP	19536157
MIRT716404	hsa-miR-3074-5p	HITS-CLIP	19536157
MIRT716403	hsa-miR-7152-5p	HITS-CLIP	19536157
MIRT661878	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT661877	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT661876	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT661875	hsa-miR-4532	HITS-CLIP	23824327
MIRT661874	hsa-miR-1470	HITS-CLIP	23824327
MIRT661873	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT661871	hsa-miR-4284	HITS-CLIP	23824327
MIRT661872	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT661870	hsa-miR-8057	HITS-CLIP	23824327
MIRT401129	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT401127	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT640449	hsa-miR-4267	HITS-CLIP	23824327
MIRT640448	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT640447	hsa-miR-4758-3p	HITS-CLIP	23824327
MIRT640446	hsa-miR-3149	HITS-CLIP	23824327
MIRT737561	hsa-miR-27a-3p	qRT-PCR	32370947
MIRT716416	hsa-miR-3606-3p	HITS-CLIP	19536157
MIRT716415	hsa-miR-513a-3p	HITS-CLIP	19536157
MIRT716414	hsa-miR-513c-3p	HITS-CLIP	19536157
MIRT716413	hsa-miR-205-3p	HITS-CLIP	19536157
MIRT716412	hsa-miR-4722-3p	HITS-CLIP	19536157
MIRT716411	hsa-miR-6727-3p	HITS-CLIP	19536157
MIRT716410	hsa-miR-6747-3p	HITS-CLIP	19536157
MIRT716409	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT716408	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT716407	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT716406	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT716405	hsa-miR-607	HITS-CLIP	19536157
MIRT716404	hsa-miR-3074-5p	HITS-CLIP	19536157
MIRT716403	hsa-miR-7152-5p	HITS-CLIP	19536157
MIRT661878	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT661877	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT661876	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT661875	hsa-miR-4532	HITS-CLIP	23824327
MIRT661874	hsa-miR-1470	HITS-CLIP	23824327
MIRT661873	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT661871	hsa-miR-4284	HITS-CLIP	23824327
MIRT661872	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT661870	hsa-miR-8057	HITS-CLIP	23824327
MIRT401129	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT401127	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT640449	hsa-miR-4267	HITS-CLIP	23824327
MIRT640448	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT640447	hsa-miR-4758-3p	HITS-CLIP	23824327
MIRT640446	hsa-miR-3149	HITS-CLIP	23824327
MIRT1222231	hsa-miR-1972	CLIP-seq
MIRT1222232	hsa-miR-3173-3p	CLIP-seq
MIRT1222233	hsa-miR-3177-5p	CLIP-seq
MIRT1222234	hsa-miR-3200-5p	CLIP-seq
MIRT1222235	hsa-miR-323-3p	CLIP-seq
MIRT1222236	hsa-miR-3607-3p	CLIP-seq
MIRT1222237	hsa-miR-3671	CLIP-seq
MIRT1222238	hsa-miR-425	CLIP-seq
MIRT1222239	hsa-miR-4446-5p	CLIP-seq
MIRT1222240	hsa-miR-4501	CLIP-seq
MIRT1222241	hsa-miR-4504	CLIP-seq
MIRT1222242	hsa-miR-4528	CLIP-seq
MIRT1222243	hsa-miR-4645-3p	CLIP-seq
MIRT1222244	hsa-miR-4682	CLIP-seq
MIRT1222245	hsa-miR-542-3p	CLIP-seq
MIRT1222246	hsa-miR-576-3p	CLIP-seq
MIRT1222247	hsa-miR-129-5p	CLIP-seq
MIRT1222248	hsa-miR-3065-5p	CLIP-seq
MIRT1222249	hsa-miR-3140-5p	CLIP-seq
MIRT1222250	hsa-miR-34b	CLIP-seq
MIRT1222251	hsa-miR-376a	CLIP-seq
MIRT1222252	hsa-miR-376b	CLIP-seq
MIRT1222253	hsa-miR-4793-5p	CLIP-seq
MIRT1222254	hsa-miR-548a-5p	CLIP-seq
MIRT1222255	hsa-miR-548ab	CLIP-seq
MIRT1222256	hsa-miR-548ak	CLIP-seq
MIRT1222257	hsa-miR-548b-5p	CLIP-seq
MIRT1222258	hsa-miR-548c-5p	CLIP-seq
MIRT1222259	hsa-miR-548d-5p	CLIP-seq
MIRT1222260	hsa-miR-548h	CLIP-seq
MIRT1222261	hsa-miR-548i	CLIP-seq
MIRT1222262	hsa-miR-548j	CLIP-seq
MIRT1222263	hsa-miR-548n	CLIP-seq
MIRT1222264	hsa-miR-548w	CLIP-seq
MIRT1222265	hsa-miR-548y	CLIP-seq
MIRT1222266	hsa-miR-559	CLIP-seq
MIRT1222267	hsa-miR-659	CLIP-seq
MIRT1222268	hsa-miR-374c	CLIP-seq
MIRT1222269	hsa-miR-4272	CLIP-seq
MIRT1222270	hsa-miR-655	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT1222272	hsa-miR-1226	CLIP-seq
MIRT1222273	hsa-miR-1238	CLIP-seq
MIRT1222274	hsa-miR-15a	CLIP-seq
MIRT1222275	hsa-miR-15b	CLIP-seq
MIRT1222276	hsa-miR-16	CLIP-seq
MIRT1222277	hsa-miR-195	CLIP-seq
MIRT1222278	hsa-miR-205	CLIP-seq
MIRT1222279	hsa-miR-214	CLIP-seq
MIRT1222280	hsa-miR-3127-5p	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT1222282	hsa-miR-3185	CLIP-seq
MIRT1222283	hsa-miR-3194-3p	CLIP-seq
MIRT1222284	hsa-miR-320a	CLIP-seq
MIRT1222285	hsa-miR-320b	CLIP-seq
MIRT1222286	hsa-miR-320c	CLIP-seq
MIRT1222287	hsa-miR-320d	CLIP-seq
MIRT1222288	hsa-miR-320e	CLIP-seq
MIRT1222289	hsa-miR-3619-5p	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT1222237	hsa-miR-3671	CLIP-seq
MIRT1222291	hsa-miR-3918	CLIP-seq
MIRT1222292	hsa-miR-424	CLIP-seq
MIRT1222293	hsa-miR-4291	CLIP-seq
MIRT1222294	hsa-miR-4294	CLIP-seq
MIRT1222295	hsa-miR-431	CLIP-seq
MIRT1222296	hsa-miR-4429	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT1222298	hsa-miR-4494	CLIP-seq
MIRT1222299	hsa-miR-4496	CLIP-seq
MIRT1222300	hsa-miR-4642	CLIP-seq
MIRT1222301	hsa-miR-4709-3p	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT1222303	hsa-miR-497	CLIP-seq
MIRT1222304	hsa-miR-499a-5p	CLIP-seq
MIRT1222305	hsa-miR-570	CLIP-seq
MIRT1222306	hsa-miR-616	CLIP-seq
MIRT1222307	hsa-miR-633	CLIP-seq
MIRT1222308	hsa-miR-761	CLIP-seq
MIRT1222309	hsa-miR-876-3p	CLIP-seq
MIRT1222310	hsa-miR-891a	CLIP-seq
MIRT1222311	hsa-miR-922	CLIP-seq
MIRT1222312	hsa-miR-924	CLIP-seq
MIRT1552200	hsa-miR-1276	CLIP-seq
MIRT1552201	hsa-miR-300	CLIP-seq
MIRT1222237	hsa-miR-3671	CLIP-seq
MIRT1552202	hsa-miR-381	CLIP-seq
MIRT1552203	hsa-miR-3920	CLIP-seq
MIRT1552204	hsa-miR-4311	CLIP-seq
MIRT1552205	hsa-miR-4662a-3p	CLIP-seq
MIRT1552206	hsa-miR-4666-3p	CLIP-seq
MIRT1552207	hsa-miR-583	CLIP-seq
MIRT1222306	hsa-miR-616	CLIP-seq
MIRT1222311	hsa-miR-922	CLIP-seq
MIRT2064364	hsa-miR-106a	CLIP-seq
MIRT2064365	hsa-miR-106b	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT2064366	hsa-miR-124	CLIP-seq
MIRT2064367	hsa-miR-17	CLIP-seq
MIRT2064368	hsa-miR-192	CLIP-seq
MIRT2064369	hsa-miR-20a	CLIP-seq
MIRT2064370	hsa-miR-20b	CLIP-seq
MIRT2064371	hsa-miR-215	CLIP-seq
MIRT2064372	hsa-miR-2355-3p	CLIP-seq
MIRT2064373	hsa-miR-23a	CLIP-seq
MIRT2064374	hsa-miR-23b	CLIP-seq
MIRT2064375	hsa-miR-23c	CLIP-seq
MIRT2064376	hsa-miR-24	CLIP-seq
MIRT2064377	hsa-miR-28-3p	CLIP-seq
MIRT2064378	hsa-miR-302a	CLIP-seq
MIRT2064379	hsa-miR-302b	CLIP-seq
MIRT2064380	hsa-miR-302c	CLIP-seq
MIRT2064381	hsa-miR-302d	CLIP-seq
MIRT2064382	hsa-miR-302e	CLIP-seq
MIRT2064383	hsa-miR-3124-3p	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT2064384	hsa-miR-3161	CLIP-seq
MIRT2064385	hsa-miR-3163	CLIP-seq
MIRT1222283	hsa-miR-3194-3p	CLIP-seq
MIRT2064386	hsa-miR-3650	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT2064387	hsa-miR-3685	CLIP-seq
MIRT2064388	hsa-miR-3714	CLIP-seq
MIRT2064389	hsa-miR-372	CLIP-seq
MIRT2064390	hsa-miR-373	CLIP-seq
MIRT2064391	hsa-miR-384	CLIP-seq
MIRT2064392	hsa-miR-3910	CLIP-seq
MIRT2064393	hsa-miR-4252	CLIP-seq
MIRT2064394	hsa-miR-4282	CLIP-seq
MIRT2064395	hsa-miR-4287	CLIP-seq
MIRT1222293	hsa-miR-4291	CLIP-seq
MIRT2064396	hsa-miR-433	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT2064397	hsa-miR-4454	CLIP-seq
MIRT2064398	hsa-miR-4469	CLIP-seq
MIRT2064399	hsa-miR-4668-5p	CLIP-seq
MIRT2064400	hsa-miR-4685-3p	CLIP-seq
MIRT2064401	hsa-miR-4695-3p	CLIP-seq
MIRT2064402	hsa-miR-4729	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT2064403	hsa-miR-4735-5p	CLIP-seq
MIRT2064404	hsa-miR-4757-5p	CLIP-seq
MIRT2064405	hsa-miR-4772-3p	CLIP-seq
MIRT2064406	hsa-miR-4775	CLIP-seq
MIRT2064407	hsa-miR-506	CLIP-seq
MIRT2064408	hsa-miR-519d	CLIP-seq
MIRT2064409	hsa-miR-520a-3p	CLIP-seq
MIRT2064410	hsa-miR-520b	CLIP-seq
MIRT2064411	hsa-miR-520c-3p	CLIP-seq
MIRT2064412	hsa-miR-520d-3p	CLIP-seq
MIRT2064413	hsa-miR-520e	CLIP-seq
MIRT2064414	hsa-miR-548an	CLIP-seq
MIRT2064415	hsa-miR-590-3p	CLIP-seq
MIRT2064416	hsa-miR-640	CLIP-seq
MIRT2064417	hsa-miR-642b	CLIP-seq
MIRT2064418	hsa-miR-676	CLIP-seq
MIRT2064419	hsa-miR-93	CLIP-seq
MIRT2064420	hsa-miR-944	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT1222272	hsa-miR-1226	CLIP-seq
MIRT2292730	hsa-miR-1227	CLIP-seq
MIRT2292731	hsa-miR-1273f	CLIP-seq
MIRT2292732	hsa-miR-142-5p	CLIP-seq
MIRT2292733	hsa-miR-197	CLIP-seq
MIRT1222279	hsa-miR-214	CLIP-seq
MIRT2064372	hsa-miR-2355-3p	CLIP-seq
MIRT2064377	hsa-miR-28-3p	CLIP-seq
MIRT2064383	hsa-miR-3124-3p	CLIP-seq
MIRT1222280	hsa-miR-3127-5p	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT2064385	hsa-miR-3163	CLIP-seq
MIRT2292734	hsa-miR-3187-3p	CLIP-seq
MIRT1222283	hsa-miR-3194-3p	CLIP-seq
MIRT1222289	hsa-miR-3619-5p	CLIP-seq
MIRT2064386	hsa-miR-3650	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT2064387	hsa-miR-3685	CLIP-seq
MIRT2292735	hsa-miR-377	CLIP-seq
MIRT2064391	hsa-miR-384	CLIP-seq
MIRT2292736	hsa-miR-3929	CLIP-seq
MIRT2292737	hsa-miR-411	CLIP-seq
MIRT2064393	hsa-miR-4252	CLIP-seq
MIRT2064394	hsa-miR-4282	CLIP-seq
MIRT1222293	hsa-miR-4291	CLIP-seq
MIRT2292738	hsa-miR-4419b	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT2292739	hsa-miR-4435	CLIP-seq
MIRT2292740	hsa-miR-4438	CLIP-seq
MIRT2292741	hsa-miR-4461	CLIP-seq
MIRT2292742	hsa-miR-4478	CLIP-seq
MIRT2064401	hsa-miR-4695-3p	CLIP-seq
MIRT2292743	hsa-miR-4701-5p	CLIP-seq
MIRT2292744	hsa-miR-4716-5p	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT2292745	hsa-miR-4755-3p	CLIP-seq
MIRT2292746	hsa-miR-4781-3p	CLIP-seq
MIRT2292747	hsa-miR-4787-5p	CLIP-seq
MIRT2292748	hsa-miR-4795-3p	CLIP-seq
MIRT2292749	hsa-miR-5095	CLIP-seq
MIRT2292750	hsa-miR-5096	CLIP-seq
MIRT2292751	hsa-miR-548s	CLIP-seq
MIRT2292752	hsa-miR-588	CLIP-seq
MIRT2064418	hsa-miR-676	CLIP-seq
MIRT1222308	hsa-miR-761	CLIP-seq
MIRT2292753	hsa-miR-891b	CLIP-seq
MIRT1222311	hsa-miR-922	CLIP-seq
MIRT1222263	hsa-miR-548n	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT1222272	hsa-miR-1226	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT2064385	hsa-miR-3163	CLIP-seq
MIRT1222283	hsa-miR-3194-3p	CLIP-seq
MIRT2064386	hsa-miR-3650	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT2064394	hsa-miR-4282	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT2392334	hsa-miR-448	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT1222272	hsa-miR-1226	CLIP-seq
MIRT2456156	hsa-miR-1273e	CLIP-seq
MIRT2456157	hsa-miR-1278	CLIP-seq
MIRT1222231	hsa-miR-1972	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT1222283	hsa-miR-3194-3p	CLIP-seq
MIRT1222234	hsa-miR-3200-5p	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT2292737	hsa-miR-411	CLIP-seq
MIRT1222294	hsa-miR-4294	CLIP-seq
MIRT1222295	hsa-miR-431	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT1222244	hsa-miR-4682	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT1222312	hsa-miR-924	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT1222272	hsa-miR-1226	CLIP-seq
MIRT2292730	hsa-miR-1227	CLIP-seq
MIRT2064366	hsa-miR-124	CLIP-seq
MIRT2590724	hsa-miR-1262	CLIP-seq
MIRT2456156	hsa-miR-1273e	CLIP-seq
MIRT2456157	hsa-miR-1278	CLIP-seq
MIRT2590725	hsa-miR-1293	CLIP-seq
MIRT2590726	hsa-miR-1297	CLIP-seq
MIRT2590727	hsa-miR-1343	CLIP-seq
MIRT2590728	hsa-miR-186	CLIP-seq
MIRT2064368	hsa-miR-192	CLIP-seq
MIRT2292733	hsa-miR-197	CLIP-seq
MIRT2590729	hsa-miR-1976	CLIP-seq
MIRT2590730	hsa-miR-21	CLIP-seq
MIRT2590731	hsa-miR-2110	CLIP-seq
MIRT2064371	hsa-miR-215	CLIP-seq
MIRT2064372	hsa-miR-2355-3p	CLIP-seq
MIRT2064376	hsa-miR-24	CLIP-seq
MIRT2590732	hsa-miR-26a	CLIP-seq
MIRT2590733	hsa-miR-26b	CLIP-seq
MIRT2064377	hsa-miR-28-3p	CLIP-seq
MIRT1552201	hsa-miR-300	CLIP-seq
MIRT2064383	hsa-miR-3124-3p	CLIP-seq
MIRT2590734	hsa-miR-3133	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT2064384	hsa-miR-3161	CLIP-seq
MIRT2064385	hsa-miR-3163	CLIP-seq
MIRT2292734	hsa-miR-3187-3p	CLIP-seq
MIRT2590735	hsa-miR-323b-3p	CLIP-seq
MIRT2590736	hsa-miR-3613-5p	CLIP-seq
MIRT2590737	hsa-miR-3622a-5p	CLIP-seq
MIRT2590738	hsa-miR-3647-3p	CLIP-seq
MIRT2064386	hsa-miR-3650	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT2590739	hsa-miR-3672	CLIP-seq
MIRT2590740	hsa-miR-3674	CLIP-seq
MIRT2064387	hsa-miR-3685	CLIP-seq
MIRT2064388	hsa-miR-3714	CLIP-seq
MIRT1552202	hsa-miR-381	CLIP-seq
MIRT2064391	hsa-miR-384	CLIP-seq
MIRT2064392	hsa-miR-3910	CLIP-seq
MIRT2590741	hsa-miR-3935	CLIP-seq
MIRT2292737	hsa-miR-411	CLIP-seq
MIRT2064393	hsa-miR-4252	CLIP-seq
MIRT2590742	hsa-miR-4271	CLIP-seq
MIRT2064394	hsa-miR-4282	CLIP-seq
MIRT2064395	hsa-miR-4287	CLIP-seq
MIRT2064396	hsa-miR-433	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT2292739	hsa-miR-4435	CLIP-seq
MIRT2292740	hsa-miR-4438	CLIP-seq
MIRT2064397	hsa-miR-4454	CLIP-seq
MIRT2292741	hsa-miR-4461	CLIP-seq
MIRT2590743	hsa-miR-4465	CLIP-seq
MIRT2064398	hsa-miR-4469	CLIP-seq
MIRT2590744	hsa-miR-4483	CLIP-seq
MIRT1552206	hsa-miR-4666-3p	CLIP-seq
MIRT2590745	hsa-miR-4668-3p	CLIP-seq
MIRT2064400	hsa-miR-4685-3p	CLIP-seq
MIRT2064401	hsa-miR-4695-3p	CLIP-seq
MIRT2590746	hsa-miR-4699-3p	CLIP-seq
MIRT2590747	hsa-miR-4701-3p	CLIP-seq
MIRT2292743	hsa-miR-4701-5p	CLIP-seq
MIRT2292744	hsa-miR-4716-5p	CLIP-seq
MIRT2590748	hsa-miR-4725-3p	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT2064403	hsa-miR-4735-5p	CLIP-seq
MIRT2064405	hsa-miR-4772-3p	CLIP-seq
MIRT2064406	hsa-miR-4775	CLIP-seq
MIRT2292746	hsa-miR-4781-3p	CLIP-seq
MIRT2292747	hsa-miR-4787-5p	CLIP-seq
MIRT2590749	hsa-miR-4789-5p	CLIP-seq
MIRT2590750	hsa-miR-491-5p	CLIP-seq
MIRT2064407	hsa-miR-506	CLIP-seq
MIRT2292749	hsa-miR-5095	CLIP-seq
MIRT2292750	hsa-miR-5096	CLIP-seq
MIRT2590751	hsa-miR-522	CLIP-seq
MIRT2590752	hsa-miR-526b	CLIP-seq
MIRT2590753	hsa-miR-548c-3p	CLIP-seq
MIRT2292751	hsa-miR-548s	CLIP-seq
MIRT2590754	hsa-miR-561	CLIP-seq
MIRT2590755	hsa-miR-580	CLIP-seq
MIRT2292752	hsa-miR-588	CLIP-seq
MIRT2064415	hsa-miR-590-3p	CLIP-seq
MIRT2590756	hsa-miR-590-5p	CLIP-seq
MIRT2064416	hsa-miR-640	CLIP-seq
MIRT2064417	hsa-miR-642b	CLIP-seq
MIRT2064418	hsa-miR-676	CLIP-seq
MIRT2292753	hsa-miR-891b	CLIP-seq
MIRT2064420	hsa-miR-944	CLIP-seq
MIRT1222271	hsa-miR-122	CLIP-seq
MIRT2687513	hsa-miR-1224-3p	CLIP-seq
MIRT1222272	hsa-miR-1226	CLIP-seq
MIRT2292730	hsa-miR-1227	CLIP-seq
MIRT2064366	hsa-miR-124	CLIP-seq
MIRT2590724	hsa-miR-1262	CLIP-seq
MIRT2456156	hsa-miR-1273e	CLIP-seq
MIRT2292731	hsa-miR-1273f	CLIP-seq
MIRT2456157	hsa-miR-1278	CLIP-seq
MIRT2590725	hsa-miR-1293	CLIP-seq
MIRT2590726	hsa-miR-1297	CLIP-seq
MIRT2687514	hsa-miR-134	CLIP-seq
MIRT2590727	hsa-miR-1343	CLIP-seq
MIRT2687515	hsa-miR-150	CLIP-seq
MIRT2590728	hsa-miR-186	CLIP-seq
MIRT2064368	hsa-miR-192	CLIP-seq
MIRT2292733	hsa-miR-197	CLIP-seq
MIRT2590729	hsa-miR-1976	CLIP-seq
MIRT2590730	hsa-miR-21	CLIP-seq
MIRT2590731	hsa-miR-2110	CLIP-seq
MIRT2064371	hsa-miR-215	CLIP-seq
MIRT2064372	hsa-miR-2355-3p	CLIP-seq
MIRT2064376	hsa-miR-24	CLIP-seq
MIRT2590732	hsa-miR-26a	CLIP-seq
MIRT2590733	hsa-miR-26b	CLIP-seq
MIRT2687516	hsa-miR-27a	CLIP-seq
MIRT2687517	hsa-miR-27b	CLIP-seq
MIRT2064377	hsa-miR-28-3p	CLIP-seq
MIRT1552201	hsa-miR-300	CLIP-seq
MIRT2687518	hsa-miR-3118	CLIP-seq
MIRT2064383	hsa-miR-3124-3p	CLIP-seq
MIRT2590734	hsa-miR-3133	CLIP-seq
MIRT1222281	hsa-miR-3135b	CLIP-seq
MIRT2687519	hsa-miR-3159	CLIP-seq
MIRT2064384	hsa-miR-3161	CLIP-seq
MIRT2064385	hsa-miR-3163	CLIP-seq
MIRT2687520	hsa-miR-3164	CLIP-seq
MIRT2292734	hsa-miR-3187-3p	CLIP-seq
MIRT2687521	hsa-miR-3199	CLIP-seq
MIRT2687522	hsa-miR-3607-5p	CLIP-seq
MIRT2590737	hsa-miR-3622a-5p	CLIP-seq
MIRT2687523	hsa-miR-3646	CLIP-seq
MIRT2590738	hsa-miR-3647-3p	CLIP-seq
MIRT2064386	hsa-miR-3650	CLIP-seq
MIRT1222290	hsa-miR-3652	CLIP-seq
MIRT2590739	hsa-miR-3672	CLIP-seq
MIRT2064387	hsa-miR-3685	CLIP-seq
MIRT2064388	hsa-miR-3714	CLIP-seq
MIRT1552202	hsa-miR-381	CLIP-seq
MIRT2064391	hsa-miR-384	CLIP-seq
MIRT2064392	hsa-miR-3910	CLIP-seq
MIRT2687524	hsa-miR-3913-3p	CLIP-seq
MIRT2687525	hsa-miR-3914	CLIP-seq
MIRT2292736	hsa-miR-3929	CLIP-seq
MIRT2292737	hsa-miR-411	CLIP-seq
MIRT2064393	hsa-miR-4252	CLIP-seq
MIRT2687526	hsa-miR-4269	CLIP-seq
MIRT2590742	hsa-miR-4271	CLIP-seq
MIRT2064394	hsa-miR-4282	CLIP-seq
MIRT2064395	hsa-miR-4287	CLIP-seq
MIRT2064396	hsa-miR-433	CLIP-seq
MIRT2292738	hsa-miR-4419b	CLIP-seq
MIRT1222297	hsa-miR-4430	CLIP-seq
MIRT2292739	hsa-miR-4435	CLIP-seq
MIRT2292740	hsa-miR-4438	CLIP-seq
MIRT2064397	hsa-miR-4454	CLIP-seq
MIRT2687527	hsa-miR-4464	CLIP-seq
MIRT2590743	hsa-miR-4465	CLIP-seq
MIRT2064398	hsa-miR-4469	CLIP-seq
MIRT2292742	hsa-miR-4478	CLIP-seq
MIRT2590744	hsa-miR-4483	CLIP-seq
MIRT2687528	hsa-miR-452	CLIP-seq
MIRT1552206	hsa-miR-4666-3p	CLIP-seq
MIRT2590745	hsa-miR-4668-3p	CLIP-seq
MIRT2687529	hsa-miR-4676-3p	CLIP-seq
MIRT2064400	hsa-miR-4685-3p	CLIP-seq
MIRT2064401	hsa-miR-4695-3p	CLIP-seq
MIRT2590746	hsa-miR-4699-3p	CLIP-seq
MIRT2590747	hsa-miR-4701-3p	CLIP-seq
MIRT2292743	hsa-miR-4701-5p	CLIP-seq
MIRT2292744	hsa-miR-4716-5p	CLIP-seq
MIRT2590748	hsa-miR-4725-3p	CLIP-seq
MIRT1222302	hsa-miR-4733-3p	CLIP-seq
MIRT2064403	hsa-miR-4735-5p	CLIP-seq
MIRT2687530	hsa-miR-4748	CLIP-seq
MIRT2292745	hsa-miR-4755-3p	CLIP-seq
MIRT2064404	hsa-miR-4757-5p	CLIP-seq
MIRT2064405	hsa-miR-4772-3p	CLIP-seq
MIRT2064406	hsa-miR-4775	CLIP-seq
MIRT2292746	hsa-miR-4781-3p	CLIP-seq
MIRT2292747	hsa-miR-4787-5p	CLIP-seq
MIRT2687531	hsa-miR-4802-3p	CLIP-seq
MIRT2687532	hsa-miR-489	CLIP-seq
MIRT2590750	hsa-miR-491-5p	CLIP-seq
MIRT2687533	hsa-miR-493	CLIP-seq
MIRT2064407	hsa-miR-506	CLIP-seq
MIRT2292749	hsa-miR-5095	CLIP-seq
MIRT2292750	hsa-miR-5096	CLIP-seq
MIRT2687534	hsa-miR-513a-5p	CLIP-seq
MIRT2590751	hsa-miR-522	CLIP-seq
MIRT2590752	hsa-miR-526b	CLIP-seq
MIRT2687535	hsa-miR-539	CLIP-seq
MIRT2590753	hsa-miR-548c-3p	CLIP-seq
MIRT2292751	hsa-miR-548s	CLIP-seq
MIRT2590754	hsa-miR-561	CLIP-seq
MIRT2292752	hsa-miR-588	CLIP-seq
MIRT2064415	hsa-miR-590-3p	CLIP-seq
MIRT2590756	hsa-miR-590-5p	CLIP-seq
MIRT2064416	hsa-miR-640	CLIP-seq
MIRT2064417	hsa-miR-642b	CLIP-seq
MIRT2687536	hsa-miR-651	CLIP-seq
MIRT2064418	hsa-miR-676	CLIP-seq
MIRT2292753	hsa-miR-891b	CLIP-seq
MIRT2064420	hsa-miR-944	CLIP-seq

Show/Hide all(31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001725	Component	Stress fiber	IBA
GO:0003779	Function	Actin binding	IBA
GO:0003779	Function	Actin binding	ISS
GO:0005080	Function	Protein kinase C binding	ISS
GO:0005515	Function	Protein binding	IPI	16549780, 25416956, 31515488, 32814053
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	ISS
GO:0005912	Component	Adherens junction	HDA	25468996
GO:0005912	Component	Adherens junction	IBA
GO:0007507	Process	Heart development	IBA
GO:0014069	Component	Postsynaptic density	IEA
GO:0014069	Component	Postsynaptic density	ISS
GO:0015629	Component	Actin cytoskeleton	IDA
GO:0016020	Component	Membrane	ISS
GO:0030018	Component	Z disc	IBA
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0031941	Component	Filamentous actin	IBA
GO:0042805	Function	Actinin binding	ISS
GO:0042995	Component	Cell projection	IEA
GO:0045202	Component	Synapse	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051371	Function	Muscle alpha-actinin binding	IBA
GO:0051963	Process	Regulation of synapse assembly	ISS
GO:0061001	Process	Regulation of dendritic spine morphogenesis	ISS
GO:0061049	Process	Cell growth involved in cardiac muscle cell development	ISS
GO:0061061	Process	Muscle structure development	IBA
GO:0098609	Process	Cell-cell adhesion	IEA
GO:0098641	Function	Cadherin binding involved in cell-cell adhesion	HDA	25468996
GO:0098793	Component	Presynapse	IEA
GO:0098794	Component	Postsynapse	IEA

MIM	HGNC	e!Ensembl
605904	17468	ENSG00000163110

Protein

UniProt ID

Q96HC4

Protein name

PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)

Protein function

May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isofo

PDB

2DAR , 2UZC

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00595	PDZ	4 → 82	PDZ domain	Domain
PF15936	DUF4749	213 → 305	Domain of unknown function (DUF4749)	Family
PF00412	LIM	420 → 475	LIM domain	Domain
PF00412	LIM	479 → 534	LIM domain	Domain
PF00412	LIM	538 → 594	LIM domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression. {ECO:0000269|PubMed:10429367, ECO:0000269|PubMed:16044170, ECO:0000269|PubMed:162

Sequence

MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG
MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTST
NNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLH
ANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPR
KHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEA
DNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKS
PSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMC
AHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECG
RCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHG
CEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF

Sequence length

596

Interactions

View interactions

	KEGG
	Cytoskeleton in muscle cells

Show/Hide Unknown Diseases (6)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS
Endometriosis	Endometriosis	N/A	N/A	GWAS
Lewy Body Disease	Lewy body disease	N/A	N/A	GWAS
Myocardial Infarction	Myocardial infarction	N/A	N/A	GWAS
Prostate cancer	Prostate cancer	N/A	N/A	GWAS
Uterine Fibroids	Uterine fibroids	N/A	N/A	GWAS

Show/Hide Text Mining Associations (27)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Bipolar Disorder	Associate	19448850, 23031404
Breast Neoplasms	Associate	12571245, 17211471, 17956604, 20461080, 24980827, 25982273, 27588391
Carcinoma Hepatocellular	Associate	20876702, 22897902
Carcinoma Non Small Cell Lung	Associate	36621614
Carcinoma Renal Cell	Associate	24955835
Cardiomyopathy Dilated	Associate	31424159, 31880413
Chondrosarcoma	Associate	35507100
Chordoma	Associate	35507100
Colorectal Neoplasms	Inhibit	19307596
Colorectal Neoplasms	Associate	27156963
Cytokine Release Syndrome	Associate	39281206
Depressive Disorder Major	Associate	24620999
Heart Defects Congenital	Associate	39281206
Heart Diseases	Associate	31880413
Hepatitis C	Associate	32344996
Hereditary Breast and Ovarian Cancer Syndrome	Associate	18419822
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	24913448
Leukemia T Cell	Associate	7957052
Lung Neoplasms	Associate	23573233
Mouth Neoplasms	Associate	24386158
Myofibrillar Myopathy	Associate	27443559
Neoplasm Metastasis	Associate	27156963, 31793711, 34912481
Neoplasms	Associate	24386158, 26061439, 26773531, 28266596, 34912481
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	8078932
Prostatic Neoplasms	Associate	23573233, 24411283, 24980827, 26773531, 32665998, 35741800
Schizophrenia	Associate	31827227
Stomach Neoplasms	Associate	27696291

PDLIM5 (PDZ and LIM domain 5)