PDLIM5 (PDZ and LIM domain 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10611 |
| Gene name | PDZ and LIM domain 5 |
| Gene symbol | PDLIM5 |
| Synonyms (NCBI Gene) |
ENHENH1L9LIM
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| Chromosome | 4 |
| Chromosome location | 4q22.3 |
| Summary | This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in |
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miRNA
miRNA information provided by mirtarbase database.
504
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
31
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96HC4 | ||||||||||||||||||||||||||||||
| Protein name | PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein) | ||||||||||||||||||||||||||||||
| Protein function | May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isofo | ||||||||||||||||||||||||||||||
| PDB | 2DAR , 2UZC | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression. {ECO:0000269|PubMed:10429367, ECO:0000269|PubMed:16044170, ECO:0000269|PubMed:162 | ||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 596 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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