VAT1 (vesicle amine transport 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10493 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Vesicle amine transport 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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VAT1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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VATI |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q21.31 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved i |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q99536 | |||||||||||||||
Protein name | Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) | |||||||||||||||
Protein function | Possesses ATPase activity (By similarity). Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin pro | |||||||||||||||
PDB | 6K9Y , 6LHR , 6LII | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in brain. Also expressed in glioblastoma cells. {ECO:0000269|PubMed:19508442}. | |||||||||||||||
Sequence |
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Sequence length | 393 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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