ACAA2 (acetyl-CoA acyltransferase 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10449 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Acetyl-CoA acyltransferase 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ACAA2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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DSAEC, T1 |
Chromosome
Chromosome number
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18 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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18q21.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | P42765 | |||||||||||||||
Protein name | 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolas | |||||||||||||||
Protein function | In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (Probable). Using free coenzyme A/CoA, catal | |||||||||||||||
PDB | 4C2J , 4C2K | |||||||||||||||
Family and domains |
Pfam
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Sequence | ||||||||||||||||
Sequence length | 397 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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