Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10395
Gene name	DLC1 Rho GTPase activating protein
Gene symbol	DLC1
Synonyms (NCBI Gene)	ARHGAP7HPSTARD12p122-RhoGAP
Chromosome	8
Chromosome location	8p22
Summary	This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes inv

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SNP ID	Visualize variation	Clinical significance	Consequence
rs121908500	T>C	Pathogenic	Genic downstream transcript variant, missense variant, coding sequence variant
rs1303000329	G>A,T	Risk-factor	Missense variant, intron variant, 5 prime UTR variant, genic downstream transcript variant, coding sequence variant
rs1563593163	G>A	Risk-factor	Stop gained, coding sequence variant, genic downstream transcript variant

665

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005042	hsa-let-7b-5p	Microarray	17699775
MIRT021186	hsa-miR-186-5p	Sequencing	20371350
MIRT031720	hsa-miR-16-5p	Sequencing	20371350
MIRT032148	hsa-let-7d-5p	Sequencing	20371350
MIRT050541	hsa-miR-20a-5p	CLASH	23622248
MIRT048014	hsa-miR-30c-5p	CLASH	23622248
MIRT036947	hsa-miR-877-3p	CLASH	23622248
MIRT054545	hsa-miR-200a-3p	Western blotqRT-PCR	23708087
MIRT054545	hsa-miR-200a-3p	Western blotqRT-PCR	23708087
MIRT054548	hsa-miR-200b-3p	Western blotqRT-PCR	23708087
MIRT054548	hsa-miR-200b-3p	Western blotqRT-PCR	23708087
MIRT054549	hsa-miR-200c-3p	Western blotqRT-PCR	23708087
MIRT054549	hsa-miR-200c-3p	Western blotqRT-PCR	23708087
MIRT054549	hsa-miR-200c-3p	Western blotqRT-PCR	23708087
MIRT054549	hsa-miR-200c-3p	Western blotqRT-PCR	23708087
MIRT054549	hsa-miR-200c-3p	Western blotqRT-PCR	23708087
MIRT054549	hsa-miR-200c-3p	Western blotqRT-PCR	23708087
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504716	hsa-miR-495-3p	PAR-CLIP	20371350
MIRT504714	hsa-miR-5688	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT573402	hsa-miR-6753-5p	PAR-CLIP	20371350
MIRT573401	hsa-miR-1226-3p	PAR-CLIP	20371350
MIRT573400	hsa-miR-4733-3p	PAR-CLIP	20371350
MIRT573399	hsa-miR-6823-5p	PAR-CLIP	20371350
MIRT573398	hsa-miR-3140-5p	PAR-CLIP	20371350
MIRT573397	hsa-miR-1266-3p	PAR-CLIP	20371350
MIRT573396	hsa-miR-412-3p	PAR-CLIP	20371350
MIRT573394	hsa-miR-6754-3p	PAR-CLIP	20371350
MIRT573395	hsa-miR-197-3p	PAR-CLIP	20371350
MIRT573393	hsa-miR-3074-5p	PAR-CLIP	20371350
MIRT573392	hsa-miR-7152-5p	PAR-CLIP	20371350
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504716	hsa-miR-495-3p	PAR-CLIP	20371350
MIRT504714	hsa-miR-5688	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT567772	hsa-miR-4295	PAR-CLIP	20371350
MIRT567771	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT567770	hsa-miR-3666	PAR-CLIP	20371350
MIRT567769	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT567768	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT567767	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT567766	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT105135	hsa-miR-5683	PAR-CLIP	20371350
MIRT567765	hsa-miR-2278	PAR-CLIP	20371350
MIRT567764	hsa-miR-3976	PAR-CLIP	20371350
MIRT567763	hsa-miR-633	PAR-CLIP	20371350
MIRT567762	hsa-miR-4671-3p	PAR-CLIP	20371350
MIRT567761	hsa-miR-374a-5p	PAR-CLIP	20371350
MIRT567760	hsa-miR-374b-5p	PAR-CLIP	20371350
MIRT567759	hsa-miR-4325	PAR-CLIP	20371350
MIRT105128	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT105129	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT567758	hsa-miR-576-3p	PAR-CLIP	20371350
MIRT567757	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT567756	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT567755	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT567754	hsa-miR-1205	PAR-CLIP	20371350
MIRT567753	hsa-miR-6132	PAR-CLIP	20371350
MIRT567752	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT567751	hsa-miR-1909-3p	PAR-CLIP	20371350
MIRT567750	hsa-miR-6722-3p	PAR-CLIP	20371350
MIRT567749	hsa-miR-4450	PAR-CLIP	20371350
MIRT567748	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT504716	hsa-miR-495-3p	PAR-CLIP	21572407
MIRT504714	hsa-miR-5688	PAR-CLIP	21572407
MIRT504715	hsa-miR-646	PAR-CLIP	21572407
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	21572407
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT504716	hsa-miR-495-3p	PAR-CLIP	21572407
MIRT504714	hsa-miR-5688	PAR-CLIP	21572407
MIRT504715	hsa-miR-646	PAR-CLIP	21572407
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	21572407
MIRT538067	hsa-miR-3617-5p	PAR-CLIP	22012620
MIRT538066	hsa-miR-641	PAR-CLIP	22012620
MIRT538065	hsa-miR-5680	PAR-CLIP	22012620
MIRT538064	hsa-miR-4496	PAR-CLIP	22012620
MIRT538063	hsa-miR-3163	PAR-CLIP	22012620
MIRT538062	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT450397	hsa-miR-3148	PAR-CLIP	22012620
MIRT450396	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT538061	hsa-miR-8065	PAR-CLIP	22012620
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT504716	hsa-miR-495-3p	PAR-CLIP	23446348
MIRT504714	hsa-miR-5688	PAR-CLIP	23446348
MIRT504715	hsa-miR-646	PAR-CLIP	23446348
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	23446348
MIRT450399	hsa-miR-548az-5p	PAR-CLIP	22100165
MIRT450398	hsa-miR-548t-5p	PAR-CLIP	22100165
MIRT450397	hsa-miR-3148	PAR-CLIP	22100165
MIRT450396	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT450395	hsa-miR-1273e	PAR-CLIP	22100165
MIRT054549	hsa-miR-200c-3p	qRT-PCR	26260454
MIRT054549	hsa-miR-200c-3p	qRT-PCR	26260454
MIRT054549	hsa-miR-200c-3p	Luciferase reporter assayqRT-PCRWestern blotting	34071861
MIRT054549	hsa-miR-200c-3p	Luciferase reporter assayqRT-PCRWestern blotting	34071861
MIRT733141	hsa-miR-106b-3p	Immunohistochemistry (IHC)Luciferase reporter assayRNA-seqqRT-PCRWestern blotting	32065214
MIRT737089	hsa-miR-873-5p	Luciferase reporter assayWestern blottingqRT-PCR	33439397
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT711441	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711440	hsa-miR-5087	HITS-CLIP	19536157
MIRT711439	hsa-miR-6740-5p	HITS-CLIP	19536157
MIRT711438	hsa-miR-3940-5p	HITS-CLIP	19536157
MIRT711437	hsa-miR-4507	HITS-CLIP	19536157
MIRT711436	hsa-miR-6839-3p	HITS-CLIP	19536157
MIRT711435	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT711434	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT711433	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711432	hsa-miR-4659a-3p	HITS-CLIP	19536157
MIRT711431	hsa-miR-4659b-3p	HITS-CLIP	19536157
MIRT711430	hsa-miR-578	HITS-CLIP	19536157
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504716	hsa-miR-495-3p	PAR-CLIP	20371350
MIRT504714	hsa-miR-5688	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT573402	hsa-miR-6753-5p	PAR-CLIP	20371350
MIRT573401	hsa-miR-1226-3p	PAR-CLIP	20371350
MIRT573400	hsa-miR-4733-3p	PAR-CLIP	20371350
MIRT573399	hsa-miR-6823-5p	PAR-CLIP	20371350
MIRT573398	hsa-miR-3140-5p	PAR-CLIP	20371350
MIRT573397	hsa-miR-1266-3p	PAR-CLIP	20371350
MIRT573396	hsa-miR-412-3p	PAR-CLIP	20371350
MIRT573394	hsa-miR-6754-3p	PAR-CLIP	20371350
MIRT573395	hsa-miR-197-3p	PAR-CLIP	20371350
MIRT573393	hsa-miR-3074-5p	PAR-CLIP	20371350
MIRT573392	hsa-miR-7152-5p	PAR-CLIP	20371350
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504716	hsa-miR-495-3p	PAR-CLIP	20371350
MIRT504714	hsa-miR-5688	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT567772	hsa-miR-4295	PAR-CLIP	20371350
MIRT567771	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT567770	hsa-miR-3666	PAR-CLIP	20371350
MIRT567769	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT567768	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT567767	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT567766	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT105135	hsa-miR-5683	PAR-CLIP	20371350
MIRT567765	hsa-miR-2278	PAR-CLIP	20371350
MIRT567764	hsa-miR-3976	PAR-CLIP	20371350
MIRT567763	hsa-miR-633	PAR-CLIP	20371350
MIRT567762	hsa-miR-4671-3p	PAR-CLIP	20371350
MIRT567761	hsa-miR-374a-5p	PAR-CLIP	20371350
MIRT567760	hsa-miR-374b-5p	PAR-CLIP	20371350
MIRT567759	hsa-miR-4325	PAR-CLIP	20371350
MIRT105128	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT105129	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT567758	hsa-miR-576-3p	PAR-CLIP	20371350
MIRT567757	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT567756	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT567755	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT567754	hsa-miR-1205	PAR-CLIP	20371350
MIRT567753	hsa-miR-6132	PAR-CLIP	20371350
MIRT567752	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT567751	hsa-miR-1909-3p	PAR-CLIP	20371350
MIRT567750	hsa-miR-6722-3p	PAR-CLIP	20371350
MIRT567749	hsa-miR-4450	PAR-CLIP	20371350
MIRT567748	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT504715	hsa-miR-646	PAR-CLIP	20371350
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT504716	hsa-miR-495-3p	PAR-CLIP	21572407
MIRT504714	hsa-miR-5688	PAR-CLIP	21572407
MIRT504715	hsa-miR-646	PAR-CLIP	21572407
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	21572407
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT504716	hsa-miR-495-3p	PAR-CLIP	21572407
MIRT504714	hsa-miR-5688	PAR-CLIP	21572407
MIRT504715	hsa-miR-646	PAR-CLIP	21572407
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	21572407
MIRT538067	hsa-miR-3617-5p	PAR-CLIP	22012620
MIRT538066	hsa-miR-641	PAR-CLIP	22012620
MIRT538065	hsa-miR-5680	PAR-CLIP	22012620
MIRT538064	hsa-miR-4496	PAR-CLIP	22012620
MIRT538063	hsa-miR-3163	PAR-CLIP	22012620
MIRT538062	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT450397	hsa-miR-3148	PAR-CLIP	22012620
MIRT450396	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT538061	hsa-miR-8065	PAR-CLIP	22012620
MIRT504717	hsa-miR-548c-3p	PAR-CLIP	23446348
MIRT504716	hsa-miR-495-3p	PAR-CLIP	23446348
MIRT504714	hsa-miR-5688	PAR-CLIP	23446348
MIRT504715	hsa-miR-646	PAR-CLIP	23446348
MIRT504713	hsa-miR-6828-5p	PAR-CLIP	23446348
MIRT450399	hsa-miR-548az-5p	PAR-CLIP	22100165
MIRT450398	hsa-miR-548t-5p	PAR-CLIP	22100165
MIRT450397	hsa-miR-3148	PAR-CLIP	22100165
MIRT450396	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT450395	hsa-miR-1273e	PAR-CLIP	22100165
MIRT737089	hsa-miR-873-5p	Luciferase reporter assayWestern blottingqRT-PCR	33439397
MIRT054545	hsa-miR-200a-3p	Luciferase reporter assayWestern blottingqRT-PCRImmunohistochemistry (IHC)	34751841
MIRT937794	hsa-miR-181a	CLIP-seq
MIRT937795	hsa-miR-181b	CLIP-seq
MIRT937796	hsa-miR-181c	CLIP-seq
MIRT937797	hsa-miR-181d	CLIP-seq
MIRT937798	hsa-miR-377	CLIP-seq
MIRT937799	hsa-miR-4262	CLIP-seq
MIRT937800	hsa-let-7a	CLIP-seq
MIRT937801	hsa-let-7b	CLIP-seq
MIRT937802	hsa-let-7c	CLIP-seq
MIRT937803	hsa-let-7d	CLIP-seq
MIRT937804	hsa-let-7e	CLIP-seq
MIRT937805	hsa-let-7f	CLIP-seq
MIRT937806	hsa-let-7g	CLIP-seq
MIRT937807	hsa-let-7i	CLIP-seq
MIRT937808	hsa-miR-1	CLIP-seq
MIRT937809	hsa-miR-101	CLIP-seq
MIRT937810	hsa-miR-106a	CLIP-seq
MIRT937811	hsa-miR-106b	CLIP-seq
MIRT937812	hsa-miR-1227	CLIP-seq
MIRT937813	hsa-miR-1276	CLIP-seq
MIRT937814	hsa-miR-128	CLIP-seq
MIRT937815	hsa-miR-129-5p	CLIP-seq
MIRT937816	hsa-miR-1299	CLIP-seq
MIRT937817	hsa-miR-130a	CLIP-seq
MIRT937818	hsa-miR-130b	CLIP-seq
MIRT937819	hsa-miR-141	CLIP-seq
MIRT937820	hsa-miR-144	CLIP-seq
MIRT937821	hsa-miR-145	CLIP-seq
MIRT937822	hsa-miR-151-3p	CLIP-seq
MIRT937823	hsa-miR-17	CLIP-seq
MIRT937824	hsa-miR-186	CLIP-seq
MIRT937825	hsa-miR-1909	CLIP-seq
MIRT937826	hsa-miR-200a	CLIP-seq
MIRT937827	hsa-miR-200b	CLIP-seq
MIRT937828	hsa-miR-200c	CLIP-seq
MIRT937829	hsa-miR-202	CLIP-seq
MIRT937830	hsa-miR-203	CLIP-seq
MIRT937831	hsa-miR-205	CLIP-seq
MIRT937832	hsa-miR-206	CLIP-seq
MIRT937833	hsa-miR-20a	CLIP-seq
MIRT937834	hsa-miR-20b	CLIP-seq
MIRT937835	hsa-miR-219-5p	CLIP-seq
MIRT937836	hsa-miR-2681	CLIP-seq
MIRT937837	hsa-miR-300	CLIP-seq
MIRT937838	hsa-miR-301a	CLIP-seq
MIRT937839	hsa-miR-301b	CLIP-seq
MIRT937840	hsa-miR-3065-5p	CLIP-seq
MIRT937841	hsa-miR-3129-3p	CLIP-seq
MIRT937842	hsa-miR-3133	CLIP-seq
MIRT937843	hsa-miR-3138	CLIP-seq
MIRT937844	hsa-miR-3153	CLIP-seq
MIRT937845	hsa-miR-3157-5p	CLIP-seq
MIRT937846	hsa-miR-3173-5p	CLIP-seq
MIRT937847	hsa-miR-3200-5p	CLIP-seq
MIRT937848	hsa-miR-340	CLIP-seq
MIRT937849	hsa-miR-3609	CLIP-seq
MIRT937850	hsa-miR-3647-3p	CLIP-seq
MIRT937851	hsa-miR-3658	CLIP-seq
MIRT937852	hsa-miR-3673	CLIP-seq
MIRT937853	hsa-miR-3676	CLIP-seq
MIRT937854	hsa-miR-374a	CLIP-seq
MIRT937855	hsa-miR-374b	CLIP-seq
MIRT937856	hsa-miR-381	CLIP-seq
MIRT937857	hsa-miR-3915	CLIP-seq
MIRT937858	hsa-miR-3928	CLIP-seq
MIRT937859	hsa-miR-3973	CLIP-seq
MIRT937860	hsa-miR-412	CLIP-seq
MIRT937861	hsa-miR-4290	CLIP-seq
MIRT937862	hsa-miR-4291	CLIP-seq
MIRT937863	hsa-miR-4302	CLIP-seq
MIRT937864	hsa-miR-4307	CLIP-seq
MIRT937865	hsa-miR-4311	CLIP-seq
MIRT937866	hsa-miR-433	CLIP-seq
MIRT937867	hsa-miR-4427	CLIP-seq
MIRT937868	hsa-miR-4445	CLIP-seq
MIRT937869	hsa-miR-4455	CLIP-seq
MIRT937870	hsa-miR-4458	CLIP-seq
MIRT937871	hsa-miR-4463	CLIP-seq
MIRT937872	hsa-miR-4484	CLIP-seq
MIRT937873	hsa-miR-4499	CLIP-seq
MIRT937874	hsa-miR-4500	CLIP-seq
MIRT937875	hsa-miR-4506	CLIP-seq
MIRT937876	hsa-miR-450b-5p	CLIP-seq
MIRT937877	hsa-miR-454	CLIP-seq
MIRT937878	hsa-miR-4649-3p	CLIP-seq
MIRT937879	hsa-miR-4659a-5p	CLIP-seq
MIRT937880	hsa-miR-4659b-5p	CLIP-seq
MIRT937881	hsa-miR-4666-3p	CLIP-seq
MIRT937882	hsa-miR-4691-3p	CLIP-seq
MIRT937883	hsa-miR-4698	CLIP-seq
MIRT937884	hsa-miR-4699-3p	CLIP-seq
MIRT937885	hsa-miR-4714-3p	CLIP-seq
MIRT937886	hsa-miR-4716-5p	CLIP-seq
MIRT937887	hsa-miR-4731-3p	CLIP-seq
MIRT937888	hsa-miR-4742-3p	CLIP-seq
MIRT937889	hsa-miR-4761-5p	CLIP-seq
MIRT937890	hsa-miR-4762-5p	CLIP-seq
MIRT937891	hsa-miR-4776-3p	CLIP-seq
MIRT937892	hsa-miR-4782-3p	CLIP-seq
MIRT937893	hsa-miR-4786-3p	CLIP-seq
MIRT937894	hsa-miR-4790-3p	CLIP-seq
MIRT937895	hsa-miR-4796-3p	CLIP-seq
MIRT937896	hsa-miR-4801	CLIP-seq
MIRT937897	hsa-miR-488	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq
MIRT937899	hsa-miR-500a	CLIP-seq
MIRT937900	hsa-miR-507	CLIP-seq
MIRT937901	hsa-miR-508-3p	CLIP-seq
MIRT937902	hsa-miR-513a-3p	CLIP-seq
MIRT937903	hsa-miR-519d	CLIP-seq
MIRT937904	hsa-miR-520d-5p	CLIP-seq
MIRT937905	hsa-miR-520g	CLIP-seq
MIRT937906	hsa-miR-520h	CLIP-seq
MIRT937907	hsa-miR-522	CLIP-seq
MIRT937908	hsa-miR-524-5p	CLIP-seq
MIRT937909	hsa-miR-526b	CLIP-seq
MIRT937910	hsa-miR-545	CLIP-seq
MIRT937911	hsa-miR-548aa	CLIP-seq
MIRT937912	hsa-miR-548ah	CLIP-seq
MIRT937913	hsa-miR-548b-3p	CLIP-seq
MIRT937914	hsa-miR-548k	CLIP-seq
MIRT937915	hsa-miR-548t	CLIP-seq
MIRT937916	hsa-miR-548u	CLIP-seq
MIRT937917	hsa-miR-557	CLIP-seq
MIRT937918	hsa-miR-582-5p	CLIP-seq
MIRT937919	hsa-miR-593	CLIP-seq
MIRT937920	hsa-miR-595	CLIP-seq
MIRT937921	hsa-miR-600	CLIP-seq
MIRT937922	hsa-miR-609	CLIP-seq
MIRT937923	hsa-miR-613	CLIP-seq
MIRT937924	hsa-miR-627	CLIP-seq
MIRT937925	hsa-miR-630	CLIP-seq
MIRT937926	hsa-miR-640	CLIP-seq
MIRT937927	hsa-miR-648	CLIP-seq
MIRT937928	hsa-miR-671-5p	CLIP-seq
MIRT937929	hsa-miR-875-3p	CLIP-seq
MIRT937930	hsa-miR-885-5p	CLIP-seq
MIRT937931	hsa-miR-93	CLIP-seq
MIRT937932	hsa-miR-98	CLIP-seq
MIRT937810	hsa-miR-106a	CLIP-seq
MIRT937811	hsa-miR-106b	CLIP-seq
MIRT937822	hsa-miR-151-3p	CLIP-seq
MIRT937823	hsa-miR-17	CLIP-seq
MIRT937833	hsa-miR-20a	CLIP-seq
MIRT937834	hsa-miR-20b	CLIP-seq
MIRT937849	hsa-miR-3609	CLIP-seq
MIRT937871	hsa-miR-4463	CLIP-seq
MIRT937873	hsa-miR-4499	CLIP-seq
MIRT937884	hsa-miR-4699-3p	CLIP-seq
MIRT937888	hsa-miR-4742-3p	CLIP-seq
MIRT937895	hsa-miR-4796-3p	CLIP-seq
MIRT937903	hsa-miR-519d	CLIP-seq
MIRT937912	hsa-miR-548ah	CLIP-seq
MIRT937925	hsa-miR-630	CLIP-seq
MIRT937931	hsa-miR-93	CLIP-seq
MIRT937815	hsa-miR-129-5p	CLIP-seq
MIRT937876	hsa-miR-450b-5p	CLIP-seq
MIRT937900	hsa-miR-507	CLIP-seq
MIRT937902	hsa-miR-513a-3p	CLIP-seq
MIRT937917	hsa-miR-557	CLIP-seq
MIRT937840	hsa-miR-3065-5p	CLIP-seq
MIRT937845	hsa-miR-3157-5p	CLIP-seq
MIRT937882	hsa-miR-4691-3p	CLIP-seq
MIRT1977583	hsa-miR-4789-3p	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq
MIRT937827	hsa-miR-200b	CLIP-seq
MIRT937828	hsa-miR-200c	CLIP-seq
MIRT937841	hsa-miR-3129-3p	CLIP-seq
MIRT1977584	hsa-miR-382	CLIP-seq
MIRT937876	hsa-miR-450b-5p	CLIP-seq
MIRT937899	hsa-miR-500a	CLIP-seq
MIRT937902	hsa-miR-513a-3p	CLIP-seq
MIRT937808	hsa-miR-1	CLIP-seq
MIRT937810	hsa-miR-106a	CLIP-seq
MIRT937811	hsa-miR-106b	CLIP-seq
MIRT937819	hsa-miR-141	CLIP-seq
MIRT937822	hsa-miR-151-3p	CLIP-seq
MIRT937823	hsa-miR-17	CLIP-seq
MIRT937794	hsa-miR-181a	CLIP-seq
MIRT937795	hsa-miR-181b	CLIP-seq
MIRT937796	hsa-miR-181c	CLIP-seq
MIRT937797	hsa-miR-181d	CLIP-seq
MIRT2212857	hsa-miR-19a	CLIP-seq
MIRT2212858	hsa-miR-19b	CLIP-seq
MIRT937826	hsa-miR-200a	CLIP-seq
MIRT937830	hsa-miR-203	CLIP-seq
MIRT937832	hsa-miR-206	CLIP-seq
MIRT937833	hsa-miR-20a	CLIP-seq
MIRT937834	hsa-miR-20b	CLIP-seq
MIRT937840	hsa-miR-3065-5p	CLIP-seq
MIRT937842	hsa-miR-3133	CLIP-seq
MIRT937845	hsa-miR-3157-5p	CLIP-seq
MIRT937849	hsa-miR-3609	CLIP-seq
MIRT937850	hsa-miR-3647-3p	CLIP-seq
MIRT937852	hsa-miR-3673	CLIP-seq
MIRT2212859	hsa-miR-3685	CLIP-seq
MIRT937798	hsa-miR-377	CLIP-seq
MIRT937799	hsa-miR-4262	CLIP-seq
MIRT937871	hsa-miR-4463	CLIP-seq
MIRT937873	hsa-miR-4499	CLIP-seq
MIRT937876	hsa-miR-450b-5p	CLIP-seq
MIRT937882	hsa-miR-4691-3p	CLIP-seq
MIRT937884	hsa-miR-4699-3p	CLIP-seq
MIRT937888	hsa-miR-4742-3p	CLIP-seq
MIRT937895	hsa-miR-4796-3p	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq
MIRT937903	hsa-miR-519d	CLIP-seq
MIRT937907	hsa-miR-522	CLIP-seq
MIRT937912	hsa-miR-548ah	CLIP-seq
MIRT937913	hsa-miR-548b-3p	CLIP-seq
MIRT937915	hsa-miR-548t	CLIP-seq
MIRT937923	hsa-miR-613	CLIP-seq
MIRT937925	hsa-miR-630	CLIP-seq
MIRT937931	hsa-miR-93	CLIP-seq
MIRT937814	hsa-miR-128	CLIP-seq
MIRT2428254	hsa-miR-204	CLIP-seq
MIRT2428255	hsa-miR-211	CLIP-seq
MIRT937837	hsa-miR-300	CLIP-seq
MIRT937840	hsa-miR-3065-5p	CLIP-seq
MIRT937843	hsa-miR-3138	CLIP-seq
MIRT937846	hsa-miR-3173-5p	CLIP-seq
MIRT937856	hsa-miR-381	CLIP-seq
MIRT937864	hsa-miR-4307	CLIP-seq
MIRT2428256	hsa-miR-4446-5p	CLIP-seq
MIRT937881	hsa-miR-4666-3p	CLIP-seq
MIRT2428257	hsa-miR-4755-5p	CLIP-seq
MIRT937894	hsa-miR-4790-3p	CLIP-seq
MIRT937897	hsa-miR-488	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq
MIRT2428258	hsa-miR-499a-5p	CLIP-seq
MIRT2428259	hsa-miR-548a-3p	CLIP-seq
MIRT2428260	hsa-miR-548e	CLIP-seq
MIRT2428261	hsa-miR-548f	CLIP-seq
MIRT2428262	hsa-miR-590-3p	CLIP-seq
MIRT2428263	hsa-miR-618	CLIP-seq
MIRT2428264	hsa-miR-623	CLIP-seq
MIRT2428265	hsa-miR-888	CLIP-seq
MIRT937800	hsa-let-7a	CLIP-seq
MIRT937801	hsa-let-7b	CLIP-seq
MIRT937802	hsa-let-7c	CLIP-seq
MIRT937803	hsa-let-7d	CLIP-seq
MIRT937804	hsa-let-7e	CLIP-seq
MIRT937805	hsa-let-7f	CLIP-seq
MIRT937806	hsa-let-7g	CLIP-seq
MIRT937807	hsa-let-7i	CLIP-seq
MIRT937810	hsa-miR-106a	CLIP-seq
MIRT937811	hsa-miR-106b	CLIP-seq
MIRT2516734	hsa-miR-1200	CLIP-seq
MIRT2516735	hsa-miR-1237	CLIP-seq
MIRT2516736	hsa-miR-1248	CLIP-seq
MIRT2516737	hsa-miR-1270	CLIP-seq
MIRT2516738	hsa-miR-146b-3p	CLIP-seq
MIRT937822	hsa-miR-151-3p	CLIP-seq
MIRT937823	hsa-miR-17	CLIP-seq
MIRT2516739	hsa-miR-185	CLIP-seq
MIRT937824	hsa-miR-186	CLIP-seq
MIRT2516740	hsa-miR-1913	CLIP-seq
MIRT2516741	hsa-miR-1973	CLIP-seq
MIRT937829	hsa-miR-202	CLIP-seq
MIRT937833	hsa-miR-20a	CLIP-seq
MIRT937834	hsa-miR-20b	CLIP-seq
MIRT2516742	hsa-miR-2115	CLIP-seq
MIRT937837	hsa-miR-300	CLIP-seq
MIRT937840	hsa-miR-3065-5p	CLIP-seq
MIRT2516743	hsa-miR-3123	CLIP-seq
MIRT937841	hsa-miR-3129-3p	CLIP-seq
MIRT937842	hsa-miR-3133	CLIP-seq
MIRT937845	hsa-miR-3157-5p	CLIP-seq
MIRT2516744	hsa-miR-3165	CLIP-seq
MIRT2516745	hsa-miR-3168	CLIP-seq
MIRT937846	hsa-miR-3173-5p	CLIP-seq
MIRT2516746	hsa-miR-3183	CLIP-seq
MIRT2516747	hsa-miR-3189-5p	CLIP-seq
MIRT2516748	hsa-miR-3190	CLIP-seq
MIRT937847	hsa-miR-3200-5p	CLIP-seq
MIRT2516749	hsa-miR-323-3p	CLIP-seq
MIRT2516750	hsa-miR-323-5p	CLIP-seq
MIRT2516751	hsa-miR-324-3p	CLIP-seq
MIRT2516752	hsa-miR-338-5p	CLIP-seq
MIRT2516753	hsa-miR-3591-3p	CLIP-seq
MIRT2516754	hsa-miR-3605-3p	CLIP-seq
MIRT937849	hsa-miR-3609	CLIP-seq
MIRT937850	hsa-miR-3647-3p	CLIP-seq
MIRT2516755	hsa-miR-3653	CLIP-seq
MIRT2516756	hsa-miR-3654	CLIP-seq
MIRT2212859	hsa-miR-3685	CLIP-seq
MIRT937856	hsa-miR-381	CLIP-seq
MIRT2516757	hsa-miR-384	CLIP-seq
MIRT2516758	hsa-miR-3977	CLIP-seq
MIRT2516759	hsa-miR-4306	CLIP-seq
MIRT2516760	hsa-miR-4327	CLIP-seq
MIRT937870	hsa-miR-4458	CLIP-seq
MIRT937871	hsa-miR-4463	CLIP-seq
MIRT2516761	hsa-miR-4470	CLIP-seq
MIRT937873	hsa-miR-4499	CLIP-seq
MIRT937874	hsa-miR-4500	CLIP-seq
MIRT2516762	hsa-miR-4502	CLIP-seq
MIRT2516763	hsa-miR-4522	CLIP-seq
MIRT2516764	hsa-miR-4531	CLIP-seq
MIRT2516765	hsa-miR-4535	CLIP-seq
MIRT2516766	hsa-miR-4644	CLIP-seq
MIRT937878	hsa-miR-4649-3p	CLIP-seq
MIRT937879	hsa-miR-4659a-5p	CLIP-seq
MIRT937880	hsa-miR-4659b-5p	CLIP-seq
MIRT2516767	hsa-miR-4668-3p	CLIP-seq
MIRT2516768	hsa-miR-4684-3p	CLIP-seq
MIRT937882	hsa-miR-4691-3p	CLIP-seq
MIRT937884	hsa-miR-4699-3p	CLIP-seq
MIRT2516769	hsa-miR-4723-3p	CLIP-seq
MIRT937888	hsa-miR-4742-3p	CLIP-seq
MIRT2516770	hsa-miR-4758-3p	CLIP-seq
MIRT937891	hsa-miR-4776-3p	CLIP-seq
MIRT2516771	hsa-miR-4777-5p	CLIP-seq
MIRT2516772	hsa-miR-4793-5p	CLIP-seq
MIRT937895	hsa-miR-4796-3p	CLIP-seq
MIRT2516773	hsa-miR-485-3p	CLIP-seq
MIRT2516774	hsa-miR-492	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq
MIRT937899	hsa-miR-500a	CLIP-seq
MIRT2516775	hsa-miR-516a-3p	CLIP-seq
MIRT2516776	hsa-miR-518d-5p	CLIP-seq
MIRT2516777	hsa-miR-519b-5p	CLIP-seq
MIRT2516778	hsa-miR-519c-5p	CLIP-seq
MIRT937903	hsa-miR-519d	CLIP-seq
MIRT2516779	hsa-miR-520c-5p	CLIP-seq
MIRT937907	hsa-miR-522	CLIP-seq
MIRT2516780	hsa-miR-526a	CLIP-seq
MIRT2516781	hsa-miR-544	CLIP-seq
MIRT2428259	hsa-miR-548a-3p	CLIP-seq
MIRT937912	hsa-miR-548ah	CLIP-seq
MIRT937913	hsa-miR-548b-3p	CLIP-seq
MIRT2428260	hsa-miR-548e	CLIP-seq
MIRT2428261	hsa-miR-548f	CLIP-seq
MIRT2516782	hsa-miR-582-3p	CLIP-seq
MIRT2428262	hsa-miR-590-3p	CLIP-seq
MIRT937921	hsa-miR-600	CLIP-seq
MIRT2428263	hsa-miR-618	CLIP-seq
MIRT2516783	hsa-miR-620	CLIP-seq
MIRT937925	hsa-miR-630	CLIP-seq
MIRT937928	hsa-miR-671-5p	CLIP-seq
MIRT2516784	hsa-miR-874	CLIP-seq
MIRT2516785	hsa-miR-876-3p	CLIP-seq
MIRT2428265	hsa-miR-888	CLIP-seq
MIRT937931	hsa-miR-93	CLIP-seq
MIRT937932	hsa-miR-98	CLIP-seq
MIRT2516735	hsa-miR-1237	CLIP-seq
MIRT2516736	hsa-miR-1248	CLIP-seq
MIRT2516737	hsa-miR-1270	CLIP-seq
MIRT2516739	hsa-miR-185	CLIP-seq
MIRT2516743	hsa-miR-3123	CLIP-seq
MIRT937841	hsa-miR-3129-3p	CLIP-seq
MIRT2516745	hsa-miR-3168	CLIP-seq
MIRT2516746	hsa-miR-3183	CLIP-seq
MIRT2516750	hsa-miR-323-5p	CLIP-seq
MIRT2516753	hsa-miR-3591-3p	CLIP-seq
MIRT2516754	hsa-miR-3605-3p	CLIP-seq
MIRT937850	hsa-miR-3647-3p	CLIP-seq
MIRT2516756	hsa-miR-3654	CLIP-seq
MIRT2212859	hsa-miR-3685	CLIP-seq
MIRT2516757	hsa-miR-384	CLIP-seq
MIRT2516759	hsa-miR-4306	CLIP-seq
MIRT2516760	hsa-miR-4327	CLIP-seq
MIRT2516763	hsa-miR-4522	CLIP-seq
MIRT2516764	hsa-miR-4531	CLIP-seq
MIRT2516765	hsa-miR-4535	CLIP-seq
MIRT2516766	hsa-miR-4644	CLIP-seq
MIRT2516767	hsa-miR-4668-3p	CLIP-seq
MIRT2516768	hsa-miR-4684-3p	CLIP-seq
MIRT2516769	hsa-miR-4723-3p	CLIP-seq
MIRT2516771	hsa-miR-4777-5p	CLIP-seq
MIRT2516772	hsa-miR-4793-5p	CLIP-seq
MIRT2516774	hsa-miR-492	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq
MIRT937899	hsa-miR-500a	CLIP-seq
MIRT2516776	hsa-miR-518d-5p	CLIP-seq
MIRT2516777	hsa-miR-519b-5p	CLIP-seq
MIRT2516778	hsa-miR-519c-5p	CLIP-seq
MIRT2516779	hsa-miR-520c-5p	CLIP-seq
MIRT937907	hsa-miR-522	CLIP-seq
MIRT2516780	hsa-miR-526a	CLIP-seq
MIRT2516781	hsa-miR-544	CLIP-seq
MIRT2428259	hsa-miR-548a-3p	CLIP-seq
MIRT2428260	hsa-miR-548e	CLIP-seq
MIRT2428261	hsa-miR-548f	CLIP-seq
MIRT2516782	hsa-miR-582-3p	CLIP-seq
MIRT2428262	hsa-miR-590-3p	CLIP-seq
MIRT2516783	hsa-miR-620	CLIP-seq
MIRT2516785	hsa-miR-876-3p	CLIP-seq
MIRT2428265	hsa-miR-888	CLIP-seq
MIRT937898	hsa-miR-495	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001843	Process	Neural tube closure	ISS
GO:0003007	Process	Heart morphogenesis	ISS
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IDA	17932950
GO:0005096	Function	GTPase activator activity	IMP	17888903
GO:0005096	Function	GTPase activator activity	TAS
GO:0005515	Function	Protein binding	IPI	16951145, 17517630, 19151751, 19158340, 24412244, 32203420, 35963849
GO:0005634	Component	Nucleus	IDA	17888903
GO:0005737	Component	Cytoplasm	IDA	16951145, 17888903
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005829	Component	Cytosol	IDA	19158340
GO:0005829	Component	Cytosol	TAS
GO:0005901	Component	Caveola	IDA	16951145
GO:0005925	Component	Focal adhesion	IBA
GO:0005925	Component	Focal adhesion	IDA	16951145, 17190795
GO:0005925	Component	Focal adhesion	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	12545165, 17932950
GO:0008289	Function	Lipid binding	IEA
GO:0016020	Component	Membrane	IEA
GO:0021575	Process	Hindbrain morphogenesis	ISS
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0030036	Process	Actin cytoskeleton organization	ISS
GO:0030336	Process	Negative regulation of cell migration	IDA	17932950, 19158340
GO:0030336	Process	Negative regulation of cell migration	IEA
GO:0030336	Process	Negative regulation of cell migration	IMP	17888903
GO:0030864	Component	Cortical actin cytoskeleton	IDA	19158340
GO:0030900	Process	Forebrain development	ISS
GO:0032587	Component	Ruffle membrane	IDA	19158340
GO:0035023	Process	Regulation of Rho protein signal transduction	IBA
GO:0035024	Process	Negative regulation of Rho protein signal transduction	IMP	16951145
GO:0035556	Process	Intracellular signal transduction	IDA	17292327
GO:0042169	Function	SH2 domain binding	IPI	17190795
GO:0045121	Component	Membrane raft	IBA
GO:0048041	Process	Focal adhesion assembly	ISS
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0051497	Process	Negative regulation of stress fiber assembly	IDA	17932950
GO:0051895	Process	Negative regulation of focal adhesion assembly	IDA	19158340
GO:0070161	Component	Anchoring junction	IEA
GO:1900119	Process	Positive regulation of execution phase of apoptosis	IDA	17888903

MIM	HGNC	e!Ensembl
604258	2897	ENSG00000164741

Q96QB1

Protein name

Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein) (DLC-1) (HP protein) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12)

Protein function

Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in

PDB

2DKY , 2GYT , 2KAP , 2LOZ , 3KUQ , 5FZT , 7TPB

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07647	SAM_2	452 → 513	SAM domain (Sterile alpha motif)	Domain
PF00620	RhoGAP	1092 → 1242	RhoGAP domain	Domain
PF01852	START	1323 → 1522	START domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

Sequence

MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS
LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC
LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE
RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP
PKDENERSTCNVVQNEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS
QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM
KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST
DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID
ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF
QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST
GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA
KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN
GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD
PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT
GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE
DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT
PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI
NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL
TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG
QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV
LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ
KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD
YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE
ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG
ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF
GHLCAAEVVKIRDSFSNQNTETKDTKSR

Sequence length

1528

Interactions

View interactions

	Reactome
			Rho GTPase cycle

141

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Carcinoma of colon	Pathogenic	rs121908500	RCV000006053

Show/Hide Unknown Diseases (14)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Cervical cancer	Benign	rs182143157, rs76713924, rs190871521	RCV005915396 RCV005915783 RCV005925147
Colorectal cancer	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	rs200102232, rs139415835, rs377127652, rs138749997, rs143324598, rs377159911, rs759392511, rs774305707, rs199759496, rs748100448, rs777832666, rs371098007, rs139778805, rs145626397, rs779873981 View all (48 more)	RCV002506827 RCV002479776 RCV005038423 RCV002499994 RCV002486958 RCV005045252 RCV005045296 RCV005050744 RCV005045328 RCV005045342 RCV005045322 RCV005045350 RCV005050758 RCV005044958 RCV005044964 RCV005050637 RCV005045038 RCV005045056 RCV005045066 RCV005045115 RCV005045106 RCV005045109 RCV005045110 RCV005045119 RCV005045143 RCV005034537 RCV005045151 RCV005045382 RCV005047325 RCV005047341 RCV005047363 RCV005047391 RCV005047392 RCV005036633 RCV005047400 RCV005047454 RCV005047489 RCV005047496 RCV005047501 RCV005051298 RCV005047658 RCV005036905 RCV005047725 RCV005051360 RCV005047782 RCV005047781 RCV005047788 RCV005047789 RCV005040596 RCV005040597 RCV005040632 RCV005051423 RCV005051424 RCV005040633 RCV005033946 RCV002481573 RCV002475986 RCV002479114 RCV002505474 RCV002505317 RCV002502751 RCV002502773 RCV002495508
DLC1-related disorder	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	rs200102232, rs73551600, rs143324598, rs140340878, rs377159911, rs371098007, rs544799456, rs774305707, rs748100448, rs199980849, rs139251311, rs376046492, rs746295250, rs150090193, rs142253103 View all (36 more)	RCV003941134 RCV003968736 RCV003958882 RCV003951302 RCV004753622 RCV003943777 RCV003963642 RCV004753628 RCV003410122 RCV003961144 RCV003926460 RCV004753596 RCV003916627 RCV003418657 RCV003961216 RCV003916631 RCV003943637 RCV003943639 RCV003961312 RCV003418663 RCV003963494 RCV003916683 RCV003943681 RCV003973609 RCV003984314 RCV003930023 RCV003396979 RCV003919046 RCV003393077 RCV003391659 RCV003414329 RCV003410791 RCV003420984 RCV003946716 RCV003893465 RCV003929650 RCV003981666 RCV003902171 RCV003901768 RCV003892249 RCV003899200 RCV003942050 RCV003944174 RCV003954933 RCV003949584 RCV003934768 RCV003947296 RCV003963822 RCV003960758 RCV003950633 RCV003958255 RCV003970373
Familial cancer of breast	Uncertain significance	rs149295187	RCV005926565
Gastric cancer	Benign	rs76713924	RCV005915784
Lung cancer	Benign; Uncertain significance	rs76713924, rs73552372, rs149295187	RCV005915787 RCV005917029 RCV005926567
Malignant tumor of esophagus	Benign	rs76713924	RCV005915782
Melanoma	Uncertain significance; Likely benign	rs149295187, rs778690040	RCV005926566 RCV005931537
Neural tube defect	risk factor	rs1563593163, rs1303000329	RCV000709686 RCV000709685
Ovarian serous cystadenocarcinoma	Benign	rs182143157, rs76713924, rs190871521	RCV005915398 RCV005915785 RCV005925149
Sarcoma	Benign	rs182143157, rs190871521	RCV005915397 RCV005925148
Thymoma	Benign	rs76713924	RCV005915786
Thyroid cancer, nonmedullary, 1	Conflicting classifications of pathogenicity	rs139243841	RCV005926598
Uterine corpus endometrial carcinoma	Benign	rs76713924, rs73552372	RCV005915788 RCV005917030

Show/Hide Text Mining Associations (68)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
3 Hydroxy 3 Methylglutaryl CoA Lyase Deficiency	Associate	17965626
Adenocarcinoma	Associate	23509688
Adenocarcinoma of Lung	Associate	23639940, 25242053, 32741804, 33612479, 33754907, 35029906, 35238419, 37790851
Adenocarcinoma of Lung	Inhibit	27174913, 33678109
Adenoma	Inhibit	23509688
Ascites	Associate	23988121
Atherosclerosis	Stimulate	30231995
Breast Neoplasms	Associate	12759748, 17418982, 22799310, 25425654, 30278072, 31110002, 35322810
Breast Neoplasms	Inhibit	27174913
Burkitt Lymphoma	Associate	17965626
Carcinogenesis	Associate	12759748, 18829524, 21217778, 34727930
Carcinoma Hepatocellular	Associate	16980951, 19440389, 22180715, 22645138, 23826380, 24443565, 26846339, 28358928, 28982593, 30827083, 33102579, 33591950, 38019231
Carcinoma Hepatocellular	Inhibit	27174913
Carcinoma Non Small Cell Lung	Inhibit	17932950
Carcinoma Non Small Cell Lung	Associate	24082123, 31059015
Carcinoma Pancreatic Ductal	Associate	23681804
Carcinoma Renal Cell	Associate	35508649
Carcinoma Squamous Cell	Associate	23625658, 34517553
Carcinoma Squamous Cell	Inhibit	27174913
Cell Transformation Neoplastic	Associate	32214200
Cholangiocarcinoma	Associate	27593557
Colorectal Neoplasms	Associate	23509688, 24694993, 26223867, 27366946, 33787596, 35280693
Death	Associate	32596987
Diabetes Mellitus	Associate	28068899
Dyskinesias	Inhibit	22002576
Dyslexia Acquired	Associate	32596987
Emphysema	Associate	26030696
Esophageal Neoplasms	Associate	35414117
Hematologic Neoplasms	Inhibit	18923442
Hereditary Breast and Ovarian Cancer Syndrome	Associate	12759748, 18593873, 22799310
Hirschsprung Disease	Associate	23270508
Hodgkin Disease	Associate	17965626
Leukemia B Cell	Associate	20224725
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	19543515
Leukemia Myeloid Acute	Associate	19543515, 24164743
Leukemia Prolymphocytic T Cell	Associate	20974048
Lung Diseases	Associate	23826380
Lung Neoplasms	Associate	20849603, 21372205, 23639940, 25425654, 32441866
Lymphatic Metastasis	Inhibit	23625658, 26239822
Lymphatic Metastasis	Associate	23681804, 23988121, 26846339
Lymphoma	Associate	17965626
Lymphoma Extranodal NK T Cell	Associate	17965626
Lymphoma Large B Cell Diffuse	Associate	17965626, 18288132
Lymphoma Non Hodgkin	Inhibit	17965626
Melanoma	Inhibit	24557030
Melanoma	Associate	32214200
Melanoma Cutaneous Malignant	Inhibit	24557030
Meningioma	Associate	27614886
Multiple Myeloma	Associate	16489177, 18923442, 23285118
Nasopharyngeal Carcinoma	Associate	20473931, 21535891, 33215427
Neoplasm Metastasis	Associate	22272086, 22799310, 23988121, 26514520, 32214200, 33591950
Neoplasm Metastasis	Inhibit	25525271, 26239822, 26846339
Neoplasms	Inhibit	16270321, 16980951, 17932950, 18460741, 18829524, 18923442, 19151751, 19440389, 19710422, 21217778, 21372205, 22064653, 22522847, 22645138, 23509688 View all (27 more)
Neoplasms	Associate	16489177, 17965626, 18288132, 18593873, 18829524, 20849603, 22002576, 22799310, 22942252, 23988121, 24082123, 24475253, 24577895, 25425654, 25525271 View all (6 more)
Neural Tube Defects	Associate	30415495
Obesity	Associate	28068899
Ovarian Neoplasms	Associate	16270321, 19487548, 23988121, 32316405, 34071861
Paget Disease Extramammary	Associate	22522847
Prostatitis	Associate	22473989
Pulmonary Arterial Hypertension	Associate	30231995
Squamous Cell Carcinoma of Head and Neck	Associate	22002576, 34051764
Stiff Skin Syndrome	Stimulate	30231995
Stomach Neoplasms	Associate	19116449, 23049225, 34933074, 35578189, 36173625
Stomach Neoplasms	Inhibit	26239822
Tertiary Lymphoid Structures	Associate	37790851
Triple Negative Breast Neoplasms	Associate	38305604
Urinary Bladder Neoplasms	Associate	24577895
Vasculitis Leukocytoclastic Cutaneous	Associate	23625658

DLC1 (DLC1 Rho GTPase activating protein)