Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10390
Gene name Gene Name - the full gene name approved by the HGNC.	Choline/ethanolamine phosphotransferase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CEPT1
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p13.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene codes for a choline/ethanolaminephosphotransferase, which functions in the synthesis of choline- or ethanolamine- containing phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

Show/Hide all(128)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023012	hsa-miR-124-3p	Microarray	18668037
MIRT023468	hsa-miR-23b-3p	Sequencing	20371350
MIRT024992	hsa-miR-183-5p	Sequencing	20371350
MIRT050143	hsa-miR-26a-5p	CLASH	23622248
MIRT444114	hsa-miR-3133	PAR-CLIP	22100165
MIRT444113	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT444112	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT444111	hsa-miR-545-5p	PAR-CLIP	22100165
MIRT444109	hsa-miR-4797-3p	PAR-CLIP	22100165
MIRT444110	hsa-miR-1253	PAR-CLIP	22100165
MIRT444108	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT444107	hsa-miR-580-3p	PAR-CLIP	22100165
MIRT444106	hsa-miR-670-3p	PAR-CLIP	22100165
MIRT444114	hsa-miR-3133	PAR-CLIP	22100165
MIRT444113	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT444112	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT444111	hsa-miR-545-5p	PAR-CLIP	22100165
MIRT444109	hsa-miR-4797-3p	PAR-CLIP	22100165
MIRT444110	hsa-miR-1253	PAR-CLIP	22100165
MIRT444108	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT444107	hsa-miR-580-3p	PAR-CLIP	22100165
MIRT444106	hsa-miR-670-3p	PAR-CLIP	22100165
MIRT444114	hsa-miR-3133	PAR-CLIP	22100165
MIRT444113	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT444112	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT444111	hsa-miR-545-5p	PAR-CLIP	22100165
MIRT444109	hsa-miR-4797-3p	PAR-CLIP	22100165
MIRT444110	hsa-miR-1253	PAR-CLIP	22100165
MIRT444108	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT444107	hsa-miR-580-3p	PAR-CLIP	22100165
MIRT444106	hsa-miR-670-3p	PAR-CLIP	22100165
MIRT444114	hsa-miR-3133	PAR-CLIP	22100165
MIRT444113	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT444112	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT444111	hsa-miR-545-5p	PAR-CLIP	22100165
MIRT444109	hsa-miR-4797-3p	PAR-CLIP	22100165
MIRT444110	hsa-miR-1253	PAR-CLIP	22100165
MIRT444108	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT444107	hsa-miR-580-3p	PAR-CLIP	22100165
MIRT444106	hsa-miR-670-3p	PAR-CLIP	22100165
MIRT886614	hsa-miR-1229	CLIP-seq
MIRT886615	hsa-miR-342-3p	CLIP-seq
MIRT886616	hsa-miR-377	CLIP-seq
MIRT886617	hsa-miR-1305	CLIP-seq
MIRT886618	hsa-miR-149	CLIP-seq
MIRT886619	hsa-miR-203	CLIP-seq
MIRT886620	hsa-miR-300	CLIP-seq
MIRT886621	hsa-miR-3064-5p	CLIP-seq
MIRT886622	hsa-miR-3126-3p	CLIP-seq
MIRT886623	hsa-miR-3199	CLIP-seq
MIRT886624	hsa-miR-381	CLIP-seq
MIRT886625	hsa-miR-3923	CLIP-seq
MIRT886626	hsa-miR-4426	CLIP-seq
MIRT886627	hsa-miR-4495	CLIP-seq
MIRT886628	hsa-miR-4496	CLIP-seq
MIRT886629	hsa-miR-4647	CLIP-seq
MIRT886630	hsa-miR-4662a-3p	CLIP-seq
MIRT886631	hsa-miR-4662b	CLIP-seq
MIRT886632	hsa-miR-4666-3p	CLIP-seq
MIRT886633	hsa-miR-4680-5p	CLIP-seq
MIRT886634	hsa-miR-4761-5p	CLIP-seq
MIRT886635	hsa-miR-4794	CLIP-seq
MIRT886636	hsa-miR-549	CLIP-seq
MIRT886637	hsa-miR-556-3p	CLIP-seq
MIRT1962933	hsa-miR-128	CLIP-seq
MIRT1962934	hsa-miR-144	CLIP-seq
MIRT886618	hsa-miR-149	CLIP-seq
MIRT1962935	hsa-miR-27a	CLIP-seq
MIRT1962936	hsa-miR-27b	CLIP-seq
MIRT886621	hsa-miR-3064-5p	CLIP-seq
MIRT886622	hsa-miR-3126-3p	CLIP-seq
MIRT1962937	hsa-miR-4427	CLIP-seq
MIRT1962938	hsa-miR-4680-3p	CLIP-seq
MIRT1962939	hsa-miR-4705	CLIP-seq
MIRT1962940	hsa-miR-4717-3p	CLIP-seq
MIRT1962941	hsa-miR-4778-5p	CLIP-seq
MIRT886635	hsa-miR-4794	CLIP-seq
MIRT1962942	hsa-miR-4795-3p	CLIP-seq
MIRT1962943	hsa-miR-665	CLIP-seq
MIRT2199280	hsa-miR-1256	CLIP-seq
MIRT1962937	hsa-miR-4427	CLIP-seq
MIRT1962938	hsa-miR-4680-3p	CLIP-seq
MIRT1962939	hsa-miR-4705	CLIP-seq
MIRT1962940	hsa-miR-4717-3p	CLIP-seq
MIRT1962943	hsa-miR-665	CLIP-seq
MIRT2502048	hsa-miR-1268	CLIP-seq
MIRT2502049	hsa-miR-1268b	CLIP-seq
MIRT2502050	hsa-miR-1296	CLIP-seq
MIRT2502051	hsa-miR-186	CLIP-seq
MIRT2502052	hsa-miR-2116	CLIP-seq
MIRT2502053	hsa-miR-2909	CLIP-seq
MIRT886620	hsa-miR-300	CLIP-seq
MIRT2502054	hsa-miR-3141	CLIP-seq
MIRT2502055	hsa-miR-340	CLIP-seq
MIRT2502056	hsa-miR-375	CLIP-seq
MIRT886616	hsa-miR-377	CLIP-seq
MIRT886624	hsa-miR-381	CLIP-seq
MIRT2502057	hsa-miR-4273	CLIP-seq
MIRT886632	hsa-miR-4666-3p	CLIP-seq
MIRT2502058	hsa-miR-4677-5p	CLIP-seq
MIRT2502059	hsa-miR-4789-5p	CLIP-seq
MIRT1962942	hsa-miR-4795-3p	CLIP-seq
MIRT2502060	hsa-miR-548n	CLIP-seq
MIRT2502061	hsa-miR-548t	CLIP-seq
MIRT2502048	hsa-miR-1268	CLIP-seq
MIRT2502049	hsa-miR-1268b	CLIP-seq
MIRT2502050	hsa-miR-1296	CLIP-seq
MIRT2502051	hsa-miR-186	CLIP-seq
MIRT2502052	hsa-miR-2116	CLIP-seq
MIRT2502053	hsa-miR-2909	CLIP-seq
MIRT886620	hsa-miR-300	CLIP-seq
MIRT2502054	hsa-miR-3141	CLIP-seq
MIRT886623	hsa-miR-3199	CLIP-seq
MIRT2502055	hsa-miR-340	CLIP-seq
MIRT2502056	hsa-miR-375	CLIP-seq
MIRT886616	hsa-miR-377	CLIP-seq
MIRT886624	hsa-miR-381	CLIP-seq
MIRT2502057	hsa-miR-4273	CLIP-seq
MIRT886626	hsa-miR-4426	CLIP-seq
MIRT886629	hsa-miR-4647	CLIP-seq
MIRT886631	hsa-miR-4662b	CLIP-seq
MIRT886632	hsa-miR-4666-3p	CLIP-seq
MIRT2502058	hsa-miR-4677-5p	CLIP-seq
MIRT2502059	hsa-miR-4789-5p	CLIP-seq
MIRT1962942	hsa-miR-4795-3p	CLIP-seq
MIRT2502060	hsa-miR-548n	CLIP-seq
MIRT2502061	hsa-miR-548t	CLIP-seq
MIRT886636	hsa-miR-549	CLIP-seq

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004142	Function	Diacylglycerol cholinephosphotransferase activity	IBA	21873635
GO:0004307	Function	Ethanolaminephosphotransferase activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005789	Component	Endoplasmic reticulum membrane	IBA	21873635
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005794	Component	Golgi apparatus	IBA	21873635
GO:0006629	Process	Lipid metabolic process	TAS	10191259
GO:0006646	Process	Phosphatidylethanolamine biosynthetic process	IBA	21873635
GO:0006646	Process	Phosphatidylethanolamine biosynthetic process	IEA
GO:0006646	Process	Phosphatidylethanolamine biosynthetic process	TAS
GO:0006656	Process	Phosphatidylcholine biosynthetic process	TAS
GO:0006657	Process	CDP-choline pathway	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0031965	Component	Nuclear membrane	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
616751	24289	ENSG00000134255

Protein

UniProt ID

Q9Y6K0

Protein name

Choline/ethanolaminephosphotransferase 1 (hCEPT1) (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22)

Protein function

Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively (PubMed:10191259, PubMed:10893425, PubMed:12216837, PubMed:37137909). Involved in protein-dependent process of phosp

PDB

8GYW , 8GYX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01066	CDP-OH_P_transf	83 → 158	CDP-alcohol phosphatidyltransferase	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:10191259}.

Sequence

MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAG
RSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYI
ACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPD
WMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIP
VLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLA
AMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLD
QYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKVSTAHSNHH

Sequence length

416

Interactions

View interactions

	KEGG		Reactome
	Phosphonate and phosphinate metabolism Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways		Synthesis of PC Synthesis of PE

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Systemic lupus erythematosus	Systemic lupus erythematosus			GWAS

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References
Associations from Text Mining
COVID 19	Associate	38327202
Hyperglycemic Hyperosmolar Nonketotic Coma	Associate	33450726
Liver Cirrhosis	Associate	37486962
Lymphoma Non Hodgkin	Associate	23992009
Maturity Onset Diabetes of the Young Type 2	Associate	33450726
Neoplasms	Associate	23992009
Non ST Elevated Myocardial Infarction	Associate	26509668

CEPT1 (choline/ethanolamine phosphotransferase 1)