Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID	10321
Gene name	Cysteine rich secretory protein 3
Gene symbol	CRISP3
Synonyms (NCBI Gene)	Aeg2CRISP-3CRS3SGP28dJ442L6.3
Chromosome	6
Chromosome location	6p12.3
Summary	This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain

Show/Hide all (48)

miRTarBase ID	miRNA	Experiments	Reference
MIRT036271	hsa-miR-1229-3p	CLASH	23622248
MIRT909781	hsa-miR-129-3p	CLIP-seq
MIRT909782	hsa-miR-151-3p	CLIP-seq
MIRT909783	hsa-miR-3123	CLIP-seq
MIRT909784	hsa-miR-3130-5p	CLIP-seq
MIRT909785	hsa-miR-3160-5p	CLIP-seq
MIRT909786	hsa-miR-33a	CLIP-seq
MIRT909787	hsa-miR-33b	CLIP-seq
MIRT909788	hsa-miR-3647-3p	CLIP-seq
MIRT909789	hsa-miR-3651	CLIP-seq
MIRT909790	hsa-miR-384	CLIP-seq
MIRT909791	hsa-miR-3919	CLIP-seq
MIRT909792	hsa-miR-4282	CLIP-seq
MIRT909793	hsa-miR-4328	CLIP-seq
MIRT909794	hsa-miR-4481	CLIP-seq
MIRT909795	hsa-miR-4482	CLIP-seq
MIRT909796	hsa-miR-4494	CLIP-seq
MIRT909797	hsa-miR-450b-5p	CLIP-seq
MIRT909798	hsa-miR-4658	CLIP-seq
MIRT909799	hsa-miR-4662a-3p	CLIP-seq
MIRT909800	hsa-miR-4687-5p	CLIP-seq
MIRT909801	hsa-miR-4699-3p	CLIP-seq
MIRT909802	hsa-miR-4745-5p	CLIP-seq
MIRT909803	hsa-miR-4758-5p	CLIP-seq
MIRT909804	hsa-miR-4797-5p	CLIP-seq
MIRT909805	hsa-miR-499a-5p	CLIP-seq
MIRT909806	hsa-miR-507	CLIP-seq
MIRT909807	hsa-miR-557	CLIP-seq
MIRT909808	hsa-miR-656	CLIP-seq
MIRT909809	hsa-miR-105	CLIP-seq
MIRT909781	hsa-miR-129-3p	CLIP-seq
MIRT909810	hsa-miR-203	CLIP-seq
MIRT909783	hsa-miR-3123	CLIP-seq
MIRT909784	hsa-miR-3130-5p	CLIP-seq
MIRT909789	hsa-miR-3651	CLIP-seq
MIRT909790	hsa-miR-384	CLIP-seq
MIRT909791	hsa-miR-3919	CLIP-seq
MIRT909793	hsa-miR-4328	CLIP-seq
MIRT909795	hsa-miR-4482	CLIP-seq
MIRT909811	hsa-miR-4684-5p	CLIP-seq
MIRT909800	hsa-miR-4687-5p	CLIP-seq
MIRT909812	hsa-miR-4768-5p	CLIP-seq
MIRT909804	hsa-miR-4797-5p	CLIP-seq
MIRT2205766	hsa-miR-331-3p	CLIP-seq
MIRT2205767	hsa-miR-3607-3p	CLIP-seq
MIRT2205768	hsa-miR-4713-5p	CLIP-seq
MIRT2205769	hsa-miR-4775	CLIP-seq
MIRT2205770	hsa-miR-590-3p	CLIP-seq

Show/Hide all (2)

Transcription factor	Regulation	Reference
AR	Unknown	11223178
ERG	Unknown	21814574

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IDA	8601434, 12009203, 12223513, 12433721
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	HDA	16502470
GO:0005615	Component	Extracellular space	IBA
GO:0006952	Process	Defense response	NAS	12647793
GO:0019953	Process	Sexual reproduction	IBA
GO:0031012	Component	Extracellular matrix	NAS	12223513
GO:0035580	Component	Specific granule lumen	TAS
GO:0042581	Component	Specific granule	IDA	8601434, 12223513
GO:0045087	Process	Innate immune response	NAS	12223513
GO:1904724	Component	Tertiary granule lumen	TAS

MIM	HGNC	e!Ensembl
618062	16904	ENSG00000096006

P54108

Protein name

Cysteine-rich secretory protein 3 (CRISP-3) (Specific granule protein of 28 kDa) (SGP28)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00188	CAP	43 → 171	Cysteine-rich secretory protein family	Domain
PF08562	Crisp	191 → 245	Crisp	Domain

Tissue specificity

TISSUE SPECIFICITY: Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon.

Sequence

MTLFPVLLFLVAGLLPSFPANEDKDPAFTALLTTQTQVQREIVNKHNELRRAVSPPARNM
LKMEWNKEAAANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSWFDEY
NDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANR
LYVPYEQGAPCASCPDNCDDGLCTNGCKYEDLYSNCKSLKLTLTCKHQLVRDSCKASCNC
SNSIY

Sequence length

245

Interactions

View interactions

	Reactome
			Neutrophil degranulation

CRISP3 (cysteine rich secretory protein 3)