Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10140
Gene name Gene Name - the full gene name approved by the HGNC.	Transducer of ERBB2, 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TOB1
Synonyms (NCBI Gene) Gene synonyms aliases	APRO5, APRO6, PIG49, TOB, TROB, TROB1
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q21.33
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor

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miRTarBase ID	miRNA	Experiments	Reference
MIRT007049	hsa-miR-218-5p	Luciferase reporter assay	23060446
MIRT050970	hsa-miR-17-5p	CLASH	23622248
MIRT039574	hsa-miR-641	CLASH	23622248
MIRT077897	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT077898	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT077902	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT077903	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT542628	hsa-miR-338-5p	PAR-CLIP	20371350
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT533591	hsa-miR-5697	PAR-CLIP	20371350
MIRT533590	hsa-miR-889-3p	PAR-CLIP	20371350
MIRT533589	hsa-miR-1297	PAR-CLIP	20371350
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	20371350
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	20371350
MIRT533586	hsa-miR-4465	PAR-CLIP	20371350
MIRT533585	hsa-miR-498	PAR-CLIP	20371350
MIRT533584	hsa-miR-1305	PAR-CLIP	20371350
MIRT288031	hsa-miR-335-3p	PAR-CLIP	20371350
MIRT077897	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT077898	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT077902	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT077903	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT542628	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	21572407
MIRT533591	hsa-miR-5697	PAR-CLIP	21572407
MIRT533590	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT533589	hsa-miR-1297	PAR-CLIP	21572407
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT533586	hsa-miR-4465	PAR-CLIP	21572407
MIRT533585	hsa-miR-498	PAR-CLIP	21572407
MIRT533584	hsa-miR-1305	PAR-CLIP	21572407
MIRT288031	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT077897	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT077898	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT077902	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT077903	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT542628	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	21572407
MIRT533591	hsa-miR-5697	PAR-CLIP	21572407
MIRT533590	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT533589	hsa-miR-1297	PAR-CLIP	21572407
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT533586	hsa-miR-4465	PAR-CLIP	21572407
MIRT533585	hsa-miR-498	PAR-CLIP	21572407
MIRT533584	hsa-miR-1305	PAR-CLIP	21572407
MIRT288031	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT077897	hsa-miR-25-3p	PAR-CLIP	22012620
MIRT077898	hsa-miR-32-5p	PAR-CLIP	22012620
MIRT077902	hsa-miR-363-3p	PAR-CLIP	22012620
MIRT077903	hsa-miR-367-3p	PAR-CLIP	22012620
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	22012620
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	22012620
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	22012620
MIRT533591	hsa-miR-5697	PAR-CLIP	22012620
MIRT533590	hsa-miR-889-3p	PAR-CLIP	22012620
MIRT533589	hsa-miR-1297	PAR-CLIP	22012620
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	22012620
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	22012620
MIRT533586	hsa-miR-4465	PAR-CLIP	22012620
MIRT533585	hsa-miR-498	PAR-CLIP	22012620
MIRT533584	hsa-miR-1305	PAR-CLIP	22012620
MIRT288031	hsa-miR-335-3p	PAR-CLIP	22012620
MIRT007049	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT007049	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT533588	hsa-miR-26a-5p	HITS-CLIP	22473208
MIRT533587	hsa-miR-26b-5p	HITS-CLIP	22473208
MIRT077900	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT077904	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT077898	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT007049	hsa-miR-218-5p	Microarray, qRT-PCR, Western blot	26540468
MIRT735801	hsa-miR-486-5p	Luciferase reporter assay, qRT-PCR	32406432
MIRT077897	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT077898	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT077902	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT077903	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT542628	hsa-miR-338-5p	PAR-CLIP	20371350
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT533591	hsa-miR-5697	PAR-CLIP	20371350
MIRT533590	hsa-miR-889-3p	PAR-CLIP	20371350
MIRT533589	hsa-miR-1297	PAR-CLIP	20371350
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	20371350
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	20371350
MIRT533586	hsa-miR-4465	PAR-CLIP	20371350
MIRT533585	hsa-miR-498	PAR-CLIP	20371350
MIRT533584	hsa-miR-1305	PAR-CLIP	20371350
MIRT288031	hsa-miR-335-3p	PAR-CLIP	20371350
MIRT077897	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT077898	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT077902	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT077903	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT542628	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	21572407
MIRT533591	hsa-miR-5697	PAR-CLIP	21572407
MIRT533590	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT533589	hsa-miR-1297	PAR-CLIP	21572407
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT533586	hsa-miR-4465	PAR-CLIP	21572407
MIRT533585	hsa-miR-498	PAR-CLIP	21572407
MIRT533584	hsa-miR-1305	PAR-CLIP	21572407
MIRT288031	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT077897	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT077898	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT077902	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT077903	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT542628	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	21572407
MIRT533591	hsa-miR-5697	PAR-CLIP	21572407
MIRT533590	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT533589	hsa-miR-1297	PAR-CLIP	21572407
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT533586	hsa-miR-4465	PAR-CLIP	21572407
MIRT533585	hsa-miR-498	PAR-CLIP	21572407
MIRT533584	hsa-miR-1305	PAR-CLIP	21572407
MIRT288031	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT077897	hsa-miR-25-3p	PAR-CLIP	22012620
MIRT077898	hsa-miR-32-5p	PAR-CLIP	22012620
MIRT077902	hsa-miR-363-3p	PAR-CLIP	22012620
MIRT077903	hsa-miR-367-3p	PAR-CLIP	22012620
MIRT077900	hsa-miR-92a-3p	PAR-CLIP	22012620
MIRT077904	hsa-miR-92b-3p	PAR-CLIP	22012620
MIRT533592	hsa-miR-4699-3p	PAR-CLIP	22012620
MIRT533591	hsa-miR-5697	PAR-CLIP	22012620
MIRT533590	hsa-miR-889-3p	PAR-CLIP	22012620
MIRT533589	hsa-miR-1297	PAR-CLIP	22012620
MIRT533588	hsa-miR-26a-5p	PAR-CLIP	22012620
MIRT533587	hsa-miR-26b-5p	PAR-CLIP	22012620
MIRT533586	hsa-miR-4465	PAR-CLIP	22012620
MIRT533585	hsa-miR-498	PAR-CLIP	22012620
MIRT533584	hsa-miR-1305	PAR-CLIP	22012620
MIRT288031	hsa-miR-335-3p	PAR-CLIP	22012620
MIRT1445818	hsa-miR-1183	CLIP-seq
MIRT1445819	hsa-miR-1208	CLIP-seq
MIRT1445820	hsa-miR-129-5p	CLIP-seq
MIRT1445821	hsa-miR-182	CLIP-seq
MIRT1445822	hsa-miR-1910	CLIP-seq
MIRT1445823	hsa-miR-1973	CLIP-seq
MIRT1445824	hsa-miR-200b	CLIP-seq
MIRT1445825	hsa-miR-200c	CLIP-seq
MIRT1445826	hsa-miR-2113	CLIP-seq
MIRT1445827	hsa-miR-2114	CLIP-seq
MIRT1445828	hsa-miR-218	CLIP-seq
MIRT1445829	hsa-miR-25	CLIP-seq
MIRT1445830	hsa-miR-26a	CLIP-seq
MIRT1445831	hsa-miR-26b	CLIP-seq
MIRT1445832	hsa-miR-2964a-5p	CLIP-seq
MIRT1445833	hsa-miR-296-5p	CLIP-seq
MIRT1445834	hsa-miR-300	CLIP-seq
MIRT1445835	hsa-miR-3134	CLIP-seq
MIRT1445836	hsa-miR-3143	CLIP-seq
MIRT1445837	hsa-miR-3144-3p	CLIP-seq
MIRT1445838	hsa-miR-3145-3p	CLIP-seq
MIRT1445839	hsa-miR-3157-5p	CLIP-seq
MIRT1445840	hsa-miR-3163	CLIP-seq
MIRT1445841	hsa-miR-3189-3p	CLIP-seq
MIRT1445842	hsa-miR-32	CLIP-seq
MIRT1445843	hsa-miR-3200-5p	CLIP-seq
MIRT1445844	hsa-miR-3201	CLIP-seq
MIRT1445845	hsa-miR-340	CLIP-seq
MIRT1445846	hsa-miR-345	CLIP-seq
MIRT1445847	hsa-miR-3617	CLIP-seq
MIRT1445848	hsa-miR-362-5p	CLIP-seq
MIRT1445849	hsa-miR-363	CLIP-seq
MIRT1445850	hsa-miR-3646	CLIP-seq
MIRT1445851	hsa-miR-3658	CLIP-seq
MIRT1445852	hsa-miR-367	CLIP-seq
MIRT1445853	hsa-miR-3713	CLIP-seq
MIRT1445854	hsa-miR-371-3p	CLIP-seq
MIRT1445855	hsa-miR-371b-3p	CLIP-seq
MIRT1445856	hsa-miR-371b-5p	CLIP-seq
MIRT1445857	hsa-miR-381	CLIP-seq
MIRT1445858	hsa-miR-4251	CLIP-seq
MIRT1445859	hsa-miR-429	CLIP-seq
MIRT1445860	hsa-miR-4307	CLIP-seq
MIRT1445861	hsa-miR-4329	CLIP-seq
MIRT1445862	hsa-miR-4426	CLIP-seq
MIRT1445863	hsa-miR-4470	CLIP-seq
MIRT1445864	hsa-miR-4473	CLIP-seq
MIRT1445865	hsa-miR-4509	CLIP-seq
MIRT1445866	hsa-miR-455-3p	CLIP-seq
MIRT1445867	hsa-miR-4647	CLIP-seq
MIRT1445868	hsa-miR-4659a-3p	CLIP-seq
MIRT1445869	hsa-miR-4659b-3p	CLIP-seq
MIRT1445870	hsa-miR-4662b	CLIP-seq
MIRT1445871	hsa-miR-4666-3p	CLIP-seq
MIRT1445872	hsa-miR-4668-3p	CLIP-seq
MIRT1445873	hsa-miR-4671-3p	CLIP-seq
MIRT1445874	hsa-miR-4691-3p	CLIP-seq
MIRT1445875	hsa-miR-4693-3p	CLIP-seq
MIRT1445876	hsa-miR-4698	CLIP-seq
MIRT1445877	hsa-miR-4731-3p	CLIP-seq
MIRT1445878	hsa-miR-4789-5p	CLIP-seq
MIRT1445879	hsa-miR-4791	CLIP-seq
MIRT1445880	hsa-miR-4795-3p	CLIP-seq
MIRT1445881	hsa-miR-4801	CLIP-seq
MIRT1445882	hsa-miR-500b	CLIP-seq
MIRT1445883	hsa-miR-501-5p	CLIP-seq
MIRT1445884	hsa-miR-502-5p	CLIP-seq
MIRT1445885	hsa-miR-511	CLIP-seq
MIRT1445886	hsa-miR-515-3p	CLIP-seq
MIRT1445887	hsa-miR-517b	CLIP-seq
MIRT1445888	hsa-miR-519e	CLIP-seq
MIRT1445889	hsa-miR-520d-5p	CLIP-seq
MIRT1445890	hsa-miR-524-5p	CLIP-seq
MIRT1445891	hsa-miR-548c-3p	CLIP-seq
MIRT1445892	hsa-miR-548p	CLIP-seq
MIRT1445893	hsa-miR-587	CLIP-seq
MIRT1445894	hsa-miR-605	CLIP-seq
MIRT1445895	hsa-miR-626	CLIP-seq
MIRT1445896	hsa-miR-635	CLIP-seq
MIRT1445897	hsa-miR-636	CLIP-seq
MIRT1445898	hsa-miR-642a	CLIP-seq
MIRT1445899	hsa-miR-888	CLIP-seq
MIRT1445900	hsa-miR-889	CLIP-seq
MIRT1445901	hsa-miR-92a	CLIP-seq
MIRT1445902	hsa-miR-92b	CLIP-seq
MIRT1445818	hsa-miR-1183	CLIP-seq
MIRT1445819	hsa-miR-1208	CLIP-seq
MIRT1445820	hsa-miR-129-5p	CLIP-seq
MIRT1445821	hsa-miR-182	CLIP-seq
MIRT1445822	hsa-miR-1910	CLIP-seq
MIRT1445824	hsa-miR-200b	CLIP-seq
MIRT1445825	hsa-miR-200c	CLIP-seq
MIRT1445826	hsa-miR-2113	CLIP-seq
MIRT1445827	hsa-miR-2114	CLIP-seq
MIRT1445828	hsa-miR-218	CLIP-seq
MIRT1445829	hsa-miR-25	CLIP-seq
MIRT1445830	hsa-miR-26a	CLIP-seq
MIRT1445831	hsa-miR-26b	CLIP-seq
MIRT1445832	hsa-miR-2964a-5p	CLIP-seq
MIRT1445835	hsa-miR-3134	CLIP-seq
MIRT1445836	hsa-miR-3143	CLIP-seq
MIRT1445837	hsa-miR-3144-3p	CLIP-seq
MIRT1445838	hsa-miR-3145-3p	CLIP-seq
MIRT1445839	hsa-miR-3157-5p	CLIP-seq
MIRT1445840	hsa-miR-3163	CLIP-seq
MIRT1445842	hsa-miR-32	CLIP-seq
MIRT1445843	hsa-miR-3200-5p	CLIP-seq
MIRT1445844	hsa-miR-3201	CLIP-seq
MIRT1445845	hsa-miR-340	CLIP-seq
MIRT1445846	hsa-miR-345	CLIP-seq
MIRT1445847	hsa-miR-3617	CLIP-seq
MIRT1445849	hsa-miR-363	CLIP-seq
MIRT1445850	hsa-miR-3646	CLIP-seq
MIRT1445851	hsa-miR-3658	CLIP-seq
MIRT1445852	hsa-miR-367	CLIP-seq
MIRT1445856	hsa-miR-371b-5p	CLIP-seq
MIRT1445858	hsa-miR-4251	CLIP-seq
MIRT1445859	hsa-miR-429	CLIP-seq
MIRT1445861	hsa-miR-4329	CLIP-seq
MIRT1445862	hsa-miR-4426	CLIP-seq
MIRT1445863	hsa-miR-4470	CLIP-seq
MIRT1445865	hsa-miR-4509	CLIP-seq
MIRT1445866	hsa-miR-455-3p	CLIP-seq
MIRT1445867	hsa-miR-4647	CLIP-seq
MIRT1445868	hsa-miR-4659a-3p	CLIP-seq
MIRT1445869	hsa-miR-4659b-3p	CLIP-seq
MIRT1445870	hsa-miR-4662b	CLIP-seq
MIRT1445874	hsa-miR-4691-3p	CLIP-seq
MIRT1445875	hsa-miR-4693-3p	CLIP-seq
MIRT1445876	hsa-miR-4698	CLIP-seq
MIRT1445877	hsa-miR-4731-3p	CLIP-seq
MIRT1445879	hsa-miR-4791	CLIP-seq
MIRT1445881	hsa-miR-4801	CLIP-seq
MIRT1445884	hsa-miR-502-5p	CLIP-seq
MIRT1445885	hsa-miR-511	CLIP-seq
MIRT1445889	hsa-miR-520d-5p	CLIP-seq
MIRT1445890	hsa-miR-524-5p	CLIP-seq
MIRT1445891	hsa-miR-548c-3p	CLIP-seq
MIRT1445892	hsa-miR-548p	CLIP-seq
MIRT1445893	hsa-miR-587	CLIP-seq
MIRT1445897	hsa-miR-636	CLIP-seq
MIRT1445898	hsa-miR-642a	CLIP-seq
MIRT1445899	hsa-miR-888	CLIP-seq
MIRT1445900	hsa-miR-889	CLIP-seq
MIRT1445901	hsa-miR-92a	CLIP-seq
MIRT1445902	hsa-miR-92b	CLIP-seq
MIRT1445818	hsa-miR-1183	CLIP-seq
MIRT1445819	hsa-miR-1208	CLIP-seq
MIRT2354497	hsa-miR-127-5p	CLIP-seq
MIRT1445821	hsa-miR-182	CLIP-seq
MIRT1445822	hsa-miR-1910	CLIP-seq
MIRT1445823	hsa-miR-1973	CLIP-seq
MIRT1445824	hsa-miR-200b	CLIP-seq
MIRT1445825	hsa-miR-200c	CLIP-seq
MIRT1445826	hsa-miR-2113	CLIP-seq
MIRT1445827	hsa-miR-2114	CLIP-seq
MIRT1445828	hsa-miR-218	CLIP-seq
MIRT1445829	hsa-miR-25	CLIP-seq
MIRT1445830	hsa-miR-26a	CLIP-seq
MIRT1445831	hsa-miR-26b	CLIP-seq
MIRT1445832	hsa-miR-2964a-5p	CLIP-seq
MIRT1445833	hsa-miR-296-5p	CLIP-seq
MIRT1445835	hsa-miR-3134	CLIP-seq
MIRT1445836	hsa-miR-3143	CLIP-seq
MIRT1445837	hsa-miR-3144-3p	CLIP-seq
MIRT1445838	hsa-miR-3145-3p	CLIP-seq
MIRT1445839	hsa-miR-3157-5p	CLIP-seq
MIRT1445840	hsa-miR-3163	CLIP-seq
MIRT1445841	hsa-miR-3189-3p	CLIP-seq
MIRT1445842	hsa-miR-32	CLIP-seq
MIRT1445843	hsa-miR-3200-5p	CLIP-seq
MIRT1445844	hsa-miR-3201	CLIP-seq
MIRT1445845	hsa-miR-340	CLIP-seq
MIRT1445846	hsa-miR-345	CLIP-seq
MIRT1445847	hsa-miR-3617	CLIP-seq
MIRT1445849	hsa-miR-363	CLIP-seq
MIRT1445850	hsa-miR-3646	CLIP-seq
MIRT1445851	hsa-miR-3658	CLIP-seq
MIRT1445852	hsa-miR-367	CLIP-seq
MIRT1445854	hsa-miR-371-3p	CLIP-seq
MIRT1445855	hsa-miR-371b-3p	CLIP-seq
MIRT1445856	hsa-miR-371b-5p	CLIP-seq
MIRT2354498	hsa-miR-374c	CLIP-seq
MIRT1445858	hsa-miR-4251	CLIP-seq
MIRT1445859	hsa-miR-429	CLIP-seq
MIRT1445861	hsa-miR-4329	CLIP-seq
MIRT1445862	hsa-miR-4426	CLIP-seq
MIRT1445863	hsa-miR-4470	CLIP-seq
MIRT1445864	hsa-miR-4473	CLIP-seq
MIRT1445865	hsa-miR-4509	CLIP-seq
MIRT1445866	hsa-miR-455-3p	CLIP-seq
MIRT1445867	hsa-miR-4647	CLIP-seq
MIRT1445868	hsa-miR-4659a-3p	CLIP-seq
MIRT1445869	hsa-miR-4659b-3p	CLIP-seq
MIRT1445870	hsa-miR-4662b	CLIP-seq
MIRT1445872	hsa-miR-4668-3p	CLIP-seq
MIRT1445873	hsa-miR-4671-3p	CLIP-seq
MIRT1445874	hsa-miR-4691-3p	CLIP-seq
MIRT1445875	hsa-miR-4693-3p	CLIP-seq
MIRT1445876	hsa-miR-4698	CLIP-seq
MIRT1445877	hsa-miR-4731-3p	CLIP-seq
MIRT1445879	hsa-miR-4791	CLIP-seq
MIRT1445881	hsa-miR-4801	CLIP-seq
MIRT1445884	hsa-miR-502-5p	CLIP-seq
MIRT1445885	hsa-miR-511	CLIP-seq
MIRT1445886	hsa-miR-515-3p	CLIP-seq
MIRT1445887	hsa-miR-517b	CLIP-seq
MIRT1445888	hsa-miR-519e	CLIP-seq
MIRT1445891	hsa-miR-548c-3p	CLIP-seq
MIRT1445893	hsa-miR-587	CLIP-seq
MIRT2354499	hsa-miR-590-3p	CLIP-seq
MIRT1445894	hsa-miR-605	CLIP-seq
MIRT1445895	hsa-miR-626	CLIP-seq
MIRT1445896	hsa-miR-635	CLIP-seq
MIRT1445897	hsa-miR-636	CLIP-seq
MIRT1445898	hsa-miR-642a	CLIP-seq
MIRT2354500	hsa-miR-655	CLIP-seq
MIRT1445899	hsa-miR-888	CLIP-seq
MIRT1445900	hsa-miR-889	CLIP-seq
MIRT1445901	hsa-miR-92a	CLIP-seq
MIRT1445902	hsa-miR-92b	CLIP-seq
MIRT1445818	hsa-miR-1183	CLIP-seq
MIRT1445819	hsa-miR-1208	CLIP-seq
MIRT1445829	hsa-miR-25	CLIP-seq
MIRT1445830	hsa-miR-26a	CLIP-seq
MIRT1445831	hsa-miR-26b	CLIP-seq
MIRT1445837	hsa-miR-3144-3p	CLIP-seq
MIRT1445842	hsa-miR-32	CLIP-seq
MIRT1445849	hsa-miR-363	CLIP-seq
MIRT1445852	hsa-miR-367	CLIP-seq
MIRT1445856	hsa-miR-371b-5p	CLIP-seq
MIRT1445876	hsa-miR-4698	CLIP-seq
MIRT1445899	hsa-miR-888	CLIP-seq
MIRT1445901	hsa-miR-92a	CLIP-seq
MIRT1445902	hsa-miR-92b	CLIP-seq
MIRT1445818	hsa-miR-1183	CLIP-seq
MIRT1445819	hsa-miR-1208	CLIP-seq
MIRT1445820	hsa-miR-129-5p	CLIP-seq
MIRT1445829	hsa-miR-25	CLIP-seq
MIRT1445830	hsa-miR-26a	CLIP-seq
MIRT1445831	hsa-miR-26b	CLIP-seq
MIRT1445834	hsa-miR-300	CLIP-seq
MIRT1445837	hsa-miR-3144-3p	CLIP-seq
MIRT1445838	hsa-miR-3145-3p	CLIP-seq
MIRT1445839	hsa-miR-3157-5p	CLIP-seq
MIRT1445840	hsa-miR-3163	CLIP-seq
MIRT1445842	hsa-miR-32	CLIP-seq
MIRT1445845	hsa-miR-340	CLIP-seq
MIRT1445849	hsa-miR-363	CLIP-seq
MIRT1445852	hsa-miR-367	CLIP-seq
MIRT1445854	hsa-miR-371-3p	CLIP-seq
MIRT1445855	hsa-miR-371b-3p	CLIP-seq
MIRT1445856	hsa-miR-371b-5p	CLIP-seq
MIRT1445857	hsa-miR-381	CLIP-seq
MIRT1445864	hsa-miR-4473	CLIP-seq
MIRT1445868	hsa-miR-4659a-3p	CLIP-seq
MIRT1445869	hsa-miR-4659b-3p	CLIP-seq
MIRT1445871	hsa-miR-4666-3p	CLIP-seq
MIRT1445873	hsa-miR-4671-3p	CLIP-seq
MIRT1445874	hsa-miR-4691-3p	CLIP-seq
MIRT1445876	hsa-miR-4698	CLIP-seq
MIRT1445878	hsa-miR-4789-5p	CLIP-seq
MIRT1445884	hsa-miR-502-5p	CLIP-seq
MIRT1445886	hsa-miR-515-3p	CLIP-seq
MIRT1445888	hsa-miR-519e	CLIP-seq
MIRT1445889	hsa-miR-520d-5p	CLIP-seq
MIRT1445890	hsa-miR-524-5p	CLIP-seq
MIRT1445891	hsa-miR-548c-3p	CLIP-seq
MIRT1445892	hsa-miR-548p	CLIP-seq
MIRT1445893	hsa-miR-587	CLIP-seq
MIRT1445899	hsa-miR-888	CLIP-seq
MIRT1445900	hsa-miR-889	CLIP-seq
MIRT1445901	hsa-miR-92a	CLIP-seq
MIRT1445902	hsa-miR-92b	CLIP-seq
MIRT1445818	hsa-miR-1183	CLIP-seq
MIRT1445819	hsa-miR-1208	CLIP-seq
MIRT1445820	hsa-miR-129-5p	CLIP-seq
MIRT2693849	hsa-miR-1322	CLIP-seq
MIRT1445821	hsa-miR-182	CLIP-seq
MIRT1445824	hsa-miR-200b	CLIP-seq
MIRT1445825	hsa-miR-200c	CLIP-seq
MIRT1445826	hsa-miR-2113	CLIP-seq
MIRT1445828	hsa-miR-218	CLIP-seq
MIRT1445829	hsa-miR-25	CLIP-seq
MIRT1445830	hsa-miR-26a	CLIP-seq
MIRT1445831	hsa-miR-26b	CLIP-seq
MIRT1445834	hsa-miR-300	CLIP-seq
MIRT1445837	hsa-miR-3144-3p	CLIP-seq
MIRT1445838	hsa-miR-3145-3p	CLIP-seq
MIRT1445839	hsa-miR-3157-5p	CLIP-seq
MIRT1445840	hsa-miR-3163	CLIP-seq
MIRT1445842	hsa-miR-32	CLIP-seq
MIRT1445845	hsa-miR-340	CLIP-seq
MIRT1445848	hsa-miR-362-5p	CLIP-seq
MIRT1445849	hsa-miR-363	CLIP-seq
MIRT1445850	hsa-miR-3646	CLIP-seq
MIRT2693850	hsa-miR-3662	CLIP-seq
MIRT1445852	hsa-miR-367	CLIP-seq
MIRT1445853	hsa-miR-3713	CLIP-seq
MIRT1445854	hsa-miR-371-3p	CLIP-seq
MIRT1445855	hsa-miR-371b-3p	CLIP-seq
MIRT1445856	hsa-miR-371b-5p	CLIP-seq
MIRT1445857	hsa-miR-381	CLIP-seq
MIRT1445859	hsa-miR-429	CLIP-seq
MIRT1445860	hsa-miR-4307	CLIP-seq
MIRT1445863	hsa-miR-4470	CLIP-seq
MIRT1445864	hsa-miR-4473	CLIP-seq
MIRT1445868	hsa-miR-4659a-3p	CLIP-seq
MIRT1445869	hsa-miR-4659b-3p	CLIP-seq
MIRT1445871	hsa-miR-4666-3p	CLIP-seq
MIRT1445873	hsa-miR-4671-3p	CLIP-seq
MIRT1445874	hsa-miR-4691-3p	CLIP-seq
MIRT1445875	hsa-miR-4693-3p	CLIP-seq
MIRT1445876	hsa-miR-4698	CLIP-seq
MIRT1445878	hsa-miR-4789-5p	CLIP-seq
MIRT1445880	hsa-miR-4795-3p	CLIP-seq
MIRT1445882	hsa-miR-500b	CLIP-seq
MIRT1445883	hsa-miR-501-5p	CLIP-seq
MIRT1445884	hsa-miR-502-5p	CLIP-seq
MIRT1445886	hsa-miR-515-3p	CLIP-seq
MIRT1445888	hsa-miR-519e	CLIP-seq
MIRT1445889	hsa-miR-520d-5p	CLIP-seq
MIRT1445890	hsa-miR-524-5p	CLIP-seq
MIRT1445891	hsa-miR-548c-3p	CLIP-seq
MIRT1445892	hsa-miR-548p	CLIP-seq
MIRT1445893	hsa-miR-587	CLIP-seq
MIRT1445897	hsa-miR-636	CLIP-seq
MIRT1445899	hsa-miR-888	CLIP-seq
MIRT1445900	hsa-miR-889	CLIP-seq
MIRT1445901	hsa-miR-92a	CLIP-seq
MIRT1445902	hsa-miR-92b	CLIP-seq

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003714	Function	Transcription corepressor activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	18377426, 19276069, 20595394, 21336257, 26496610, 28514442, 31515488, 32814053
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	8632892, 19276069
GO:0010468	Process	Regulation of gene expression	IBA	21873635
GO:0017148	Process	Negative regulation of translation	IDA	23236473
GO:0030014	Component	CCR4-NOT complex	IDA	21336257
GO:0030514	Process	Negative regulation of BMP signaling pathway	IEA
GO:0030971	Function	Receptor tyrosine kinase binding	IDA	8632892
GO:0045668	Process	Negative regulation of osteoblast differentiation	IEA
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IEA
GO:0046332	Function	SMAD binding	IEA
GO:0060212	Process	Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	IDA	18377426
GO:0060213	Process	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	IDA	21336257
GO:0060390	Process	Regulation of SMAD protein signal transduction	IEA
GO:1900153	Process	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IDA	21336257

MIM	HGNC	e!Ensembl
605523	11979	ENSG00000141232

Protein

UniProt ID

P50616

Protein name

Protein Tob1 (Transducer of erbB-2 1)

Protein function

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:23236473, PubMed:8632892). Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which

PDB

2D5R , 2Z15 , 5CI8 , 5CI9

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07742	BTG	1 → 112	BTG family	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous.

Sequence

MQLEIQVALNFIISYLYNKLPRRRVNIFGEELERLLKKKYEGHWYPEKPYKGSGFRCIHI
GEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVDDNNEN
GCELDKEIKNSFNPEAQVFMPISDPASSVSSSPSPPFGHSAAVSPTFMPRSTQPLTFTTA
TFAATKFGSTKMKNSGRSNKVARTSPINLGLNVNDLLKQKAISSSMHSLYGLGLGSQQQP
QQQQQPAQPPPPPPPPQQQQQQKTSALSPNAKEFIFPNMQGQGSSTNGMFPGDSPLNLSP
LQYSNAFDVFAAYGGLNEKSFVDGLNFSLNNMQYSNQQFQPVMAN

Sequence length

345

Interactions

View interactions

	KEGG
	RNA degradation

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Endometriosis	Endometriosis		21063030	ClinVar

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	20132413, 26165839, 28922388, 33173433, 33786619, 40169858
Carcinogenesis	Associate	22710759
Cartilage Diseases	Associate	15743474
Chondrosarcoma	Inhibit	15743474
Crohn Disease	Associate	33247598
Encephalomyelitis Autoimmune Experimental	Inhibit	18689680
Glioblastoma	Associate	39652629
Hemoglobinuria Paroxysmal	Associate	28630090
Inflammatory Bowel Diseases	Associate	33247598
Lung Neoplasms	Inhibit	22158108
Multiple Sclerosis	Associate	18689680
Neoplasm Metastasis	Inhibit	22158108
Neoplasm Metastasis	Associate	26572149
Neoplasms	Associate	21765901, 31891232
Neoplasms	Inhibit	22710759, 26165839, 26609221, 28922388, 35186488
Neuroblastoma	Associate	11423116
Ovarian Neoplasms	Stimulate	38494731
Pancreatic Neoplasms	Inhibit	31891232
Pancreatic Neoplasms	Associate	37753069
Stomach Neoplasms	Associate	21533545, 26572149, 35465266
Stomach Neoplasms	Inhibit	22710759, 35186488
Thyroid Cancer Papillary	Associate	36917092
White Coat Hypertension	Associate	18689680

TOB1 (transducer of ERBB2, 1)