ACTR1A (actin related protein 1A)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10121 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Actin related protein 1A |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ACTR1A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ARP1, Arp1A, CTRN1 |
Chromosome
Chromosome number
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10 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10q24.32 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P61163 | ||||||||||
Protein name | Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog) | ||||||||||
Protein function | Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules. | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 376 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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