ACTR2 (actin related protein 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10097 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Actin related protein 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ACTR2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ARP2 |
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Chromosome
Chromosome number
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2 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p14 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamel |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P61160 | ||||||||||
| Protein name | Actin-related protein 2 (Actin-like protein 2) | ||||||||||
| Protein function | ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks i | ||||||||||
| PDB | 6UHC , 6YW6 , 6YW7 , 8P94 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 394 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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