CDH10 (cadherin 10)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1008
Gene name Gene Name - the full gene name approved by the HGNC.
Cadherin 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CDH10
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5p14.2-p14.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(5)
miRTarBase ID miRNA Experiments Reference
MIRT879290 hsa-miR-3163 CLIP-seq
MIRT879291 hsa-miR-3662 CLIP-seq
MIRT879292 hsa-miR-432 CLIP-seq
MIRT879293 hsa-miR-450b-5p CLIP-seq
MIRT879294 hsa-miR-579 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(18)
GO ID Ontology Definition Evidence Reference
GO:0000902 Process Cell morphogenesis IBA 21873635
GO:0005509 Function Calcium ion binding IBA 21873635
GO:0005886 Component Plasma membrane TAS
GO:0005912 Component Adherens junction IBA 21873635
GO:0007043 Process Cell-cell junction assembly IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
604555 1749 ENSG00000040731
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9Y6N8
Protein name Cadherin-10 (T2-cadherin)
Protein function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00028 Cadherin 60 → 151 Cadherin domain Domain
PF00028 Cadherin 165 → 260 Cadherin domain Domain
PF00028 Cadherin 274 → 376 Cadherin domain Domain
PF00028 Cadherin 389 → 480 Cadherin domain Domain
PF00028 Cadherin 493 → 587 Cadherin domain Domain
PF01049 Cadherin_C 635 → 782 Cadherin cytoplasmic region Family
Tissue specificity TISSUE SPECIFICITY: Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung. {ECO:0000269|PubMed:10386616}.
Sequence
Sequence length 788
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Adherens junctions interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (3)
Causal
Disease term Disease name dbSNP ID References
Autism spectrum disorder Autism Spectrum Disorders rs724159978, rs75184679, rs119103221, rs9332964, rs121912562, rs1594344233, rs727504317, rs111033204, rs1801086, rs587784464, rs724159948, rs764659822, rs794727977, rs796052733, rs796052728
View all (51 more)		 28191889
Autism Autistic Disorder rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699
View all (8 more)		 19404256
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
Show/Hide Text Mining Associations (20)
Associations from Text Mining
Disease Name Relationship Type References
Autism Spectrum Disorder Associate 19404256, 28281572, 33076578
Carcinogenesis Associate 28124395
Carcinoma Pancreatic Ductal Associate 28124395
Carcinoma Squamous Cell Associate 26503331
Colorectal Neoplasms Associate 24898286, 24951259
Death Associate 18711181
Endometrial Neoplasms Associate 28448305
Heart Defects Congenital Associate 30342662
Hyperkeratosis Epidermolytic Inhibit 35421402
Lung Diseases Associate 28448305