Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10049
Gene name Gene Name - the full gene name approved by the HGNC.	DnaJ heat shock protein family (Hsp40) member B6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DNAJB6
Synonyms (NCBI Gene) Gene synonyms aliases	DJ4, DnaJ, HHDJ1, HSJ-2, HSJ2, LGMD1D, LGMD1E, LGMDD1, MRJ, MSJ-1
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q36.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the `J-domain` and function as one of the two major classes of molecular chaperones involved in a wide range of ce

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SNP ID	Visualize variation	Clinical significance	Consequence
rs142974468	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, coding sequence variant, missense variant
rs145897776	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, intron variant, coding sequence variant
rs149278319	C>A,G,T	Benign-likely-benign, pathogenic, likely-benign	Coding sequence variant, missense variant, synonymous variant
rs369098407	T>G	Conflicting-interpretations-of-pathogenicity, likely-benign	Synonymous variant, genic downstream transcript variant, coding sequence variant, intron variant
rs373354100	C>A,G	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs375911119	A>C	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant
rs387907046	T>C	Pathogenic	Missense variant, coding sequence variant
rs387907047	C>G	Pathogenic	Missense variant, coding sequence variant
rs387907150	T>A,C	Likely-pathogenic, pathogenic	Missense variant, coding sequence variant
rs552613359	G>A,T	Conflicting-interpretations-of-pathogenicity	Intron variant
rs556999563	G>A	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, coding sequence variant, missense variant
rs759982570	C>G,T	Pathogenic	Synonymous variant, coding sequence variant, missense variant
rs869320700	T>G	Pathogenic	Coding sequence variant, missense variant
rs869320701	T>A,G	Pathogenic, likely-pathogenic	Coding sequence variant, missense variant
rs869320702	G>A	Pathogenic	Intron variant
rs886042415	T>G	Conflicting-interpretations-of-pathogenicity	Intron variant
rs1252030610	G>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Coding sequence variant, intron variant, synonymous variant, genic downstream transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020424	hsa-miR-106b-5p	Microarray	17242205
MIRT025240	hsa-miR-34a-5p	Proteomics	21566225
MIRT025240	hsa-miR-34a-5p	Proteomics	21566225
MIRT025240	hsa-miR-34a-5p	Proteomics	21566225
MIRT362256	hsa-miR-6813-3p	PAR-CLIP	20371350
MIRT362252	hsa-miR-432-5p	PAR-CLIP	20371350
MIRT567730	hsa-miR-3198	PAR-CLIP	20371350
MIRT567729	hsa-miR-4309	PAR-CLIP	20371350
MIRT221379	hsa-miR-138-5p	PAR-CLIP	20371350
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT507539	hsa-miR-4280	PAR-CLIP	20371350
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	20371350
MIRT221392	hsa-miR-7978	PAR-CLIP	20371350
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	20371350
MIRT507537	hsa-miR-6131	PAR-CLIP	20371350
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	20371350
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	20371350
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	20371350
MIRT507535	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	20371350
MIRT507534	hsa-let-7c-3p	PAR-CLIP	20371350
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	20371350
MIRT221379	hsa-miR-138-5p	PAR-CLIP	21572407
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT507539	hsa-miR-4280	PAR-CLIP	21572407
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	21572407
MIRT221392	hsa-miR-7978	PAR-CLIP	21572407
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	21572407
MIRT507537	hsa-miR-6131	PAR-CLIP	21572407
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	21572407
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	21572407
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	21572407
MIRT507535	hsa-miR-142-3p	PAR-CLIP	21572407
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	21572407
MIRT507534	hsa-let-7c-3p	PAR-CLIP	21572407
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	21572407
MIRT538046	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT538045	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT538044	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT538043	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT538042	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT538041	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT538040	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT020424	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT538039	hsa-miR-519a-3p	PAR-CLIP	22012620
MIRT538038	hsa-miR-519b-3p	PAR-CLIP	22012620
MIRT538037	hsa-miR-519c-3p	PAR-CLIP	22012620
MIRT221376	hsa-miR-3529-3p	PAR-CLIP	22012620
MIRT538036	hsa-miR-4797-5p	PAR-CLIP	22012620
MIRT538035	hsa-miR-520g-3p	PAR-CLIP	22012620
MIRT538034	hsa-miR-520h	PAR-CLIP	22012620
MIRT538033	hsa-miR-4756-3p	PAR-CLIP	22012620
MIRT538032	hsa-miR-5689	PAR-CLIP	22012620
MIRT244404	hsa-miR-200b-3p	PAR-CLIP	22012620
MIRT244406	hsa-miR-200c-3p	PAR-CLIP	22012620
MIRT244407	hsa-miR-429	PAR-CLIP	22012620
MIRT244410	hsa-miR-944	PAR-CLIP	22012620
MIRT502613	hsa-miR-4724-5p	PAR-CLIP	22012620
MIRT502614	hsa-miR-4999-3p	PAR-CLIP	22012620
MIRT502612	hsa-miR-3137	PAR-CLIP	22012620
MIRT502611	hsa-miR-20b-3p	PAR-CLIP	22012620
MIRT502610	hsa-miR-3686	PAR-CLIP	22012620
MIRT244403	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT502609	hsa-miR-4743-3p	PAR-CLIP	22012620
MIRT502608	hsa-miR-4652-3p	PAR-CLIP	22012620
MIRT221379	hsa-miR-138-5p	PAR-CLIP	23446348
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT507539	hsa-miR-4280	PAR-CLIP	23446348
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	23446348
MIRT221392	hsa-miR-7978	PAR-CLIP	23446348
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	23446348
MIRT507537	hsa-miR-6131	PAR-CLIP	23446348
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	23446348
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	23446348
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	23446348
MIRT507535	hsa-miR-142-3p	PAR-CLIP	23446348
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	23446348
MIRT507534	hsa-let-7c-3p	PAR-CLIP	23446348
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	23446348
MIRT221379	hsa-miR-138-5p	PAR-CLIP	23446348
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT507539	hsa-miR-4280	PAR-CLIP	23446348
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	23446348
MIRT221392	hsa-miR-7978	PAR-CLIP	23446348
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	23446348
MIRT507537	hsa-miR-6131	PAR-CLIP	23446348
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	23446348
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	23446348
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	23446348
MIRT507535	hsa-miR-142-3p	PAR-CLIP	23446348
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	23446348
MIRT507534	hsa-let-7c-3p	PAR-CLIP	23446348
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	23446348
MIRT244404	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT244406	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT244407	hsa-miR-429	PAR-CLIP	24398324
MIRT244410	hsa-miR-944	PAR-CLIP	24398324
MIRT502613	hsa-miR-4724-5p	PAR-CLIP	24398324
MIRT502614	hsa-miR-4999-3p	PAR-CLIP	24398324
MIRT502612	hsa-miR-3137	PAR-CLIP	24398324
MIRT502611	hsa-miR-20b-3p	PAR-CLIP	24398324
MIRT502610	hsa-miR-3686	PAR-CLIP	24398324
MIRT244403	hsa-miR-203a-3p	PAR-CLIP	24398324
MIRT502609	hsa-miR-4743-3p	PAR-CLIP	24398324
MIRT502608	hsa-miR-4652-3p	PAR-CLIP	24398324
MIRT362256	hsa-miR-6813-3p	PAR-CLIP	20371350
MIRT362252	hsa-miR-432-5p	PAR-CLIP	20371350
MIRT567730	hsa-miR-3198	PAR-CLIP	20371350
MIRT567729	hsa-miR-4309	PAR-CLIP	20371350
MIRT221379	hsa-miR-138-5p	PAR-CLIP	20371350
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT507539	hsa-miR-4280	PAR-CLIP	20371350
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	20371350
MIRT221392	hsa-miR-7978	PAR-CLIP	20371350
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	20371350
MIRT507537	hsa-miR-6131	PAR-CLIP	20371350
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	20371350
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	20371350
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	20371350
MIRT507535	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	20371350
MIRT507534	hsa-let-7c-3p	PAR-CLIP	20371350
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	20371350
MIRT221379	hsa-miR-138-5p	PAR-CLIP	21572407
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT507539	hsa-miR-4280	PAR-CLIP	21572407
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	21572407
MIRT221392	hsa-miR-7978	PAR-CLIP	21572407
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	21572407
MIRT507537	hsa-miR-6131	PAR-CLIP	21572407
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	21572407
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	21572407
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	21572407
MIRT507535	hsa-miR-142-3p	PAR-CLIP	21572407
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	21572407
MIRT507534	hsa-let-7c-3p	PAR-CLIP	21572407
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	21572407
MIRT538046	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT538045	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT538044	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT538043	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT538042	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT538041	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT538040	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT020424	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT538039	hsa-miR-519a-3p	PAR-CLIP	22012620
MIRT538038	hsa-miR-519b-3p	PAR-CLIP	22012620
MIRT538037	hsa-miR-519c-3p	PAR-CLIP	22012620
MIRT221376	hsa-miR-3529-3p	PAR-CLIP	22012620
MIRT538036	hsa-miR-4797-5p	PAR-CLIP	22012620
MIRT538035	hsa-miR-520g-3p	PAR-CLIP	22012620
MIRT538034	hsa-miR-520h	PAR-CLIP	22012620
MIRT538033	hsa-miR-4756-3p	PAR-CLIP	22012620
MIRT538032	hsa-miR-5689	PAR-CLIP	22012620
MIRT244404	hsa-miR-200b-3p	PAR-CLIP	22012620
MIRT244406	hsa-miR-200c-3p	PAR-CLIP	22012620
MIRT244407	hsa-miR-429	PAR-CLIP	22012620
MIRT244410	hsa-miR-944	PAR-CLIP	22012620
MIRT502613	hsa-miR-4724-5p	PAR-CLIP	22012620
MIRT502614	hsa-miR-4999-3p	PAR-CLIP	22012620
MIRT502612	hsa-miR-3137	PAR-CLIP	22012620
MIRT502611	hsa-miR-20b-3p	PAR-CLIP	22012620
MIRT502610	hsa-miR-3686	PAR-CLIP	22012620
MIRT244403	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT502609	hsa-miR-4743-3p	PAR-CLIP	22012620
MIRT502608	hsa-miR-4652-3p	PAR-CLIP	22012620
MIRT221379	hsa-miR-138-5p	PAR-CLIP	23446348
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT507539	hsa-miR-4280	PAR-CLIP	23446348
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	23446348
MIRT221392	hsa-miR-7978	PAR-CLIP	23446348
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	23446348
MIRT507537	hsa-miR-6131	PAR-CLIP	23446348
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	23446348
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	23446348
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	23446348
MIRT507535	hsa-miR-142-3p	PAR-CLIP	23446348
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	23446348
MIRT507534	hsa-let-7c-3p	PAR-CLIP	23446348
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	23446348
MIRT221379	hsa-miR-138-5p	PAR-CLIP	23446348
MIRT221380	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT507539	hsa-miR-4280	PAR-CLIP	23446348
MIRT221391	hsa-miR-6872-3p	PAR-CLIP	23446348
MIRT221392	hsa-miR-7978	PAR-CLIP	23446348
MIRT507538	hsa-miR-133a-5p	PAR-CLIP	23446348
MIRT507537	hsa-miR-6131	PAR-CLIP	23446348
MIRT221386	hsa-miR-4694-5p	PAR-CLIP	23446348
MIRT507536	hsa-miR-3177-5p	PAR-CLIP	23446348
MIRT221382	hsa-miR-3152-3p	PAR-CLIP	23446348
MIRT507535	hsa-miR-142-3p	PAR-CLIP	23446348
MIRT221388	hsa-miR-5581-3p	PAR-CLIP	23446348
MIRT507534	hsa-let-7c-3p	PAR-CLIP	23446348
MIRT221387	hsa-miR-3591-5p	PAR-CLIP	23446348
MIRT244404	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT244406	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT244407	hsa-miR-429	PAR-CLIP	24398324
MIRT244410	hsa-miR-944	PAR-CLIP	24398324
MIRT502613	hsa-miR-4724-5p	PAR-CLIP	24398324
MIRT502614	hsa-miR-4999-3p	PAR-CLIP	24398324
MIRT502612	hsa-miR-3137	PAR-CLIP	24398324
MIRT502611	hsa-miR-20b-3p	PAR-CLIP	24398324
MIRT502610	hsa-miR-3686	PAR-CLIP	24398324
MIRT244403	hsa-miR-203a-3p	PAR-CLIP	24398324
MIRT502609	hsa-miR-4743-3p	PAR-CLIP	24398324
MIRT502608	hsa-miR-4652-3p	PAR-CLIP	24398324
MIRT940210	hsa-miR-105	CLIP-seq
MIRT940211	hsa-miR-106a	CLIP-seq
MIRT940212	hsa-miR-106b	CLIP-seq
MIRT940213	hsa-miR-1179	CLIP-seq
MIRT940214	hsa-miR-1202	CLIP-seq
MIRT940215	hsa-miR-1276	CLIP-seq
MIRT940216	hsa-miR-1282	CLIP-seq
MIRT940217	hsa-miR-1323	CLIP-seq
MIRT940218	hsa-miR-1324	CLIP-seq
MIRT940219	hsa-miR-138	CLIP-seq
MIRT940220	hsa-miR-17	CLIP-seq
MIRT940221	hsa-miR-200b	CLIP-seq
MIRT940222	hsa-miR-200c	CLIP-seq
MIRT940223	hsa-miR-203	CLIP-seq
MIRT940224	hsa-miR-2053	CLIP-seq
MIRT940225	hsa-miR-20a	CLIP-seq
MIRT940226	hsa-miR-20b	CLIP-seq
MIRT940227	hsa-miR-214	CLIP-seq
MIRT940228	hsa-miR-2355-3p	CLIP-seq
MIRT940229	hsa-miR-23a	CLIP-seq
MIRT940230	hsa-miR-23b	CLIP-seq
MIRT940231	hsa-miR-23c	CLIP-seq
MIRT940232	hsa-miR-24	CLIP-seq
MIRT940233	hsa-miR-2467-5p	CLIP-seq
MIRT940234	hsa-miR-27a	CLIP-seq
MIRT940235	hsa-miR-27b	CLIP-seq
MIRT940236	hsa-miR-299-3p	CLIP-seq
MIRT940237	hsa-miR-3117-5p	CLIP-seq
MIRT940238	hsa-miR-3121-3p	CLIP-seq
MIRT940239	hsa-miR-3128	CLIP-seq
MIRT940240	hsa-miR-3160-3p	CLIP-seq
MIRT940241	hsa-miR-3194-5p	CLIP-seq
MIRT940242	hsa-miR-331-5p	CLIP-seq
MIRT940243	hsa-miR-338-3p	CLIP-seq
MIRT940244	hsa-miR-340	CLIP-seq
MIRT940245	hsa-miR-3613-3p	CLIP-seq
MIRT940246	hsa-miR-3619-5p	CLIP-seq
MIRT940247	hsa-miR-3655	CLIP-seq
MIRT940248	hsa-miR-3664-3p	CLIP-seq
MIRT940249	hsa-miR-371b-5p	CLIP-seq
MIRT940250	hsa-miR-382	CLIP-seq
MIRT940251	hsa-miR-3907	CLIP-seq
MIRT940252	hsa-miR-3942-3p	CLIP-seq
MIRT940253	hsa-miR-3972	CLIP-seq
MIRT940254	hsa-miR-425	CLIP-seq
MIRT940255	hsa-miR-4281	CLIP-seq
MIRT940256	hsa-miR-4284	CLIP-seq
MIRT940257	hsa-miR-4310	CLIP-seq
MIRT940258	hsa-miR-4311	CLIP-seq
MIRT940259	hsa-miR-432	CLIP-seq
MIRT940260	hsa-miR-4326	CLIP-seq
MIRT940261	hsa-miR-4422	CLIP-seq
MIRT940262	hsa-miR-4432	CLIP-seq
MIRT940263	hsa-miR-4444	CLIP-seq
MIRT940264	hsa-miR-4487	CLIP-seq
MIRT940265	hsa-miR-4491	CLIP-seq
MIRT940266	hsa-miR-4657	CLIP-seq
MIRT940267	hsa-miR-4690-5p	CLIP-seq
MIRT940268	hsa-miR-4704-5p	CLIP-seq
MIRT940269	hsa-miR-4729	CLIP-seq
MIRT940270	hsa-miR-4744	CLIP-seq
MIRT940271	hsa-miR-4775	CLIP-seq
MIRT940272	hsa-miR-500a	CLIP-seq
MIRT940273	hsa-miR-501-3p	CLIP-seq
MIRT940274	hsa-miR-502-3p	CLIP-seq
MIRT940275	hsa-miR-510	CLIP-seq
MIRT940276	hsa-miR-513a-5p	CLIP-seq
MIRT940277	hsa-miR-519a	CLIP-seq
MIRT940278	hsa-miR-519d	CLIP-seq
MIRT940279	hsa-miR-520g	CLIP-seq
MIRT940280	hsa-miR-522	CLIP-seq
MIRT940281	hsa-miR-548o	CLIP-seq
MIRT940282	hsa-miR-548u	CLIP-seq
MIRT940283	hsa-miR-556-3p	CLIP-seq
MIRT940284	hsa-miR-556-5p	CLIP-seq
MIRT940285	hsa-miR-558	CLIP-seq
MIRT940286	hsa-miR-569	CLIP-seq
MIRT940287	hsa-miR-583	CLIP-seq
MIRT940288	hsa-miR-636	CLIP-seq
MIRT940289	hsa-miR-656	CLIP-seq
MIRT940290	hsa-miR-676	CLIP-seq
MIRT940291	hsa-miR-761	CLIP-seq
MIRT940292	hsa-miR-767-5p	CLIP-seq
MIRT940293	hsa-miR-873	CLIP-seq
MIRT940294	hsa-miR-888	CLIP-seq
MIRT940295	hsa-miR-93	CLIP-seq
MIRT940228	hsa-miR-2355-3p	CLIP-seq
MIRT940247	hsa-miR-3655	CLIP-seq
MIRT940268	hsa-miR-4704-5p	CLIP-seq
MIRT940290	hsa-miR-676	CLIP-seq
MIRT940210	hsa-miR-105	CLIP-seq
MIRT940215	hsa-miR-1276	CLIP-seq
MIRT940218	hsa-miR-1324	CLIP-seq
MIRT940219	hsa-miR-138	CLIP-seq
MIRT940224	hsa-miR-2053	CLIP-seq
MIRT940227	hsa-miR-214	CLIP-seq
MIRT940228	hsa-miR-2355-3p	CLIP-seq
MIRT940229	hsa-miR-23a	CLIP-seq
MIRT940230	hsa-miR-23b	CLIP-seq
MIRT940231	hsa-miR-23c	CLIP-seq
MIRT940232	hsa-miR-24	CLIP-seq
MIRT940233	hsa-miR-2467-5p	CLIP-seq
MIRT940234	hsa-miR-27a	CLIP-seq
MIRT940235	hsa-miR-27b	CLIP-seq
MIRT940237	hsa-miR-3117-5p	CLIP-seq
MIRT940238	hsa-miR-3121-3p	CLIP-seq
MIRT940239	hsa-miR-3128	CLIP-seq
MIRT1978067	hsa-miR-3130-5p	CLIP-seq
MIRT1978068	hsa-miR-3143	CLIP-seq
MIRT940240	hsa-miR-3160-3p	CLIP-seq
MIRT1978069	hsa-miR-323-3p	CLIP-seq
MIRT940244	hsa-miR-340	CLIP-seq
MIRT940246	hsa-miR-3619-5p	CLIP-seq
MIRT940247	hsa-miR-3655	CLIP-seq
MIRT1978070	hsa-miR-3667-5p	CLIP-seq
MIRT940249	hsa-miR-371b-5p	CLIP-seq
MIRT940251	hsa-miR-3907	CLIP-seq
MIRT940252	hsa-miR-3942-3p	CLIP-seq
MIRT940254	hsa-miR-425	CLIP-seq
MIRT940255	hsa-miR-4281	CLIP-seq
MIRT940256	hsa-miR-4284	CLIP-seq
MIRT940258	hsa-miR-4311	CLIP-seq
MIRT940259	hsa-miR-432	CLIP-seq
MIRT940260	hsa-miR-4326	CLIP-seq
MIRT940262	hsa-miR-4432	CLIP-seq
MIRT1978071	hsa-miR-4482	CLIP-seq
MIRT940264	hsa-miR-4487	CLIP-seq
MIRT940267	hsa-miR-4690-5p	CLIP-seq
MIRT940268	hsa-miR-4704-5p	CLIP-seq
MIRT940269	hsa-miR-4729	CLIP-seq
MIRT940270	hsa-miR-4744	CLIP-seq
MIRT1978072	hsa-miR-4804-3p	CLIP-seq
MIRT940272	hsa-miR-500a	CLIP-seq
MIRT940276	hsa-miR-513a-5p	CLIP-seq
MIRT940277	hsa-miR-519a	CLIP-seq
MIRT940280	hsa-miR-522	CLIP-seq
MIRT1978073	hsa-miR-543	CLIP-seq
MIRT940284	hsa-miR-556-5p	CLIP-seq
MIRT940285	hsa-miR-558	CLIP-seq
MIRT940286	hsa-miR-569	CLIP-seq
MIRT940287	hsa-miR-583	CLIP-seq
MIRT1978074	hsa-miR-634	CLIP-seq
MIRT940288	hsa-miR-636	CLIP-seq
MIRT940290	hsa-miR-676	CLIP-seq
MIRT940291	hsa-miR-761	CLIP-seq
MIRT940294	hsa-miR-888	CLIP-seq
MIRT940213	hsa-miR-1179	CLIP-seq
MIRT940214	hsa-miR-1202	CLIP-seq
MIRT940215	hsa-miR-1276	CLIP-seq
MIRT940218	hsa-miR-1324	CLIP-seq
MIRT940219	hsa-miR-138	CLIP-seq
MIRT940221	hsa-miR-200b	CLIP-seq
MIRT940222	hsa-miR-200c	CLIP-seq
MIRT940223	hsa-miR-203	CLIP-seq
MIRT940227	hsa-miR-214	CLIP-seq
MIRT940228	hsa-miR-2355-3p	CLIP-seq
MIRT940229	hsa-miR-23a	CLIP-seq
MIRT940230	hsa-miR-23b	CLIP-seq
MIRT940231	hsa-miR-23c	CLIP-seq
MIRT940232	hsa-miR-24	CLIP-seq
MIRT940233	hsa-miR-2467-5p	CLIP-seq
MIRT940234	hsa-miR-27a	CLIP-seq
MIRT940235	hsa-miR-27b	CLIP-seq
MIRT940236	hsa-miR-299-3p	CLIP-seq
MIRT940237	hsa-miR-3117-5p	CLIP-seq
MIRT940239	hsa-miR-3128	CLIP-seq
MIRT940240	hsa-miR-3160-3p	CLIP-seq
MIRT940241	hsa-miR-3194-5p	CLIP-seq
MIRT940242	hsa-miR-331-5p	CLIP-seq
MIRT940243	hsa-miR-338-3p	CLIP-seq
MIRT940244	hsa-miR-340	CLIP-seq
MIRT940246	hsa-miR-3619-5p	CLIP-seq
MIRT940247	hsa-miR-3655	CLIP-seq
MIRT940249	hsa-miR-371b-5p	CLIP-seq
MIRT940250	hsa-miR-382	CLIP-seq
MIRT940252	hsa-miR-3942-3p	CLIP-seq
MIRT940253	hsa-miR-3972	CLIP-seq
MIRT940254	hsa-miR-425	CLIP-seq
MIRT940255	hsa-miR-4281	CLIP-seq
MIRT940256	hsa-miR-4284	CLIP-seq
MIRT940257	hsa-miR-4310	CLIP-seq
MIRT940258	hsa-miR-4311	CLIP-seq
MIRT940259	hsa-miR-432	CLIP-seq
MIRT940262	hsa-miR-4432	CLIP-seq
MIRT940264	hsa-miR-4487	CLIP-seq
MIRT940265	hsa-miR-4491	CLIP-seq
MIRT940266	hsa-miR-4657	CLIP-seq
MIRT940267	hsa-miR-4690-5p	CLIP-seq
MIRT940268	hsa-miR-4704-5p	CLIP-seq
MIRT940270	hsa-miR-4744	CLIP-seq
MIRT940276	hsa-miR-513a-5p	CLIP-seq
MIRT940284	hsa-miR-556-5p	CLIP-seq
MIRT940285	hsa-miR-558	CLIP-seq
MIRT2213625	hsa-miR-570	CLIP-seq
MIRT940287	hsa-miR-583	CLIP-seq
MIRT940290	hsa-miR-676	CLIP-seq
MIRT940291	hsa-miR-761	CLIP-seq
MIRT940294	hsa-miR-888	CLIP-seq
MIRT2213626	hsa-miR-889	CLIP-seq
MIRT940218	hsa-miR-1324	CLIP-seq
MIRT940219	hsa-miR-138	CLIP-seq
MIRT940227	hsa-miR-214	CLIP-seq
MIRT940229	hsa-miR-23a	CLIP-seq
MIRT940230	hsa-miR-23b	CLIP-seq
MIRT940231	hsa-miR-23c	CLIP-seq
MIRT940232	hsa-miR-24	CLIP-seq
MIRT940234	hsa-miR-27a	CLIP-seq
MIRT940235	hsa-miR-27b	CLIP-seq
MIRT940237	hsa-miR-3117-5p	CLIP-seq
MIRT940246	hsa-miR-3619-5p	CLIP-seq
MIRT940252	hsa-miR-3942-3p	CLIP-seq
MIRT940256	hsa-miR-4284	CLIP-seq
MIRT940267	hsa-miR-4690-5p	CLIP-seq
MIRT940276	hsa-miR-513a-5p	CLIP-seq
MIRT940291	hsa-miR-761	CLIP-seq
MIRT940210	hsa-miR-105	CLIP-seq
MIRT940211	hsa-miR-106a	CLIP-seq
MIRT940212	hsa-miR-106b	CLIP-seq
MIRT940213	hsa-miR-1179	CLIP-seq
MIRT940214	hsa-miR-1202	CLIP-seq
MIRT940215	hsa-miR-1276	CLIP-seq
MIRT940216	hsa-miR-1282	CLIP-seq
MIRT940217	hsa-miR-1323	CLIP-seq
MIRT940218	hsa-miR-1324	CLIP-seq
MIRT940219	hsa-miR-138	CLIP-seq
MIRT940220	hsa-miR-17	CLIP-seq
MIRT940223	hsa-miR-203	CLIP-seq
MIRT940224	hsa-miR-2053	CLIP-seq
MIRT940225	hsa-miR-20a	CLIP-seq
MIRT940226	hsa-miR-20b	CLIP-seq
MIRT940227	hsa-miR-214	CLIP-seq
MIRT940228	hsa-miR-2355-3p	CLIP-seq
MIRT940229	hsa-miR-23a	CLIP-seq
MIRT940230	hsa-miR-23b	CLIP-seq
MIRT940231	hsa-miR-23c	CLIP-seq
MIRT940232	hsa-miR-24	CLIP-seq
MIRT940234	hsa-miR-27a	CLIP-seq
MIRT940235	hsa-miR-27b	CLIP-seq
MIRT2517435	hsa-miR-302a	CLIP-seq
MIRT2517436	hsa-miR-302b	CLIP-seq
MIRT2517437	hsa-miR-302c	CLIP-seq
MIRT2517438	hsa-miR-302d	CLIP-seq
MIRT2517439	hsa-miR-302e	CLIP-seq
MIRT940237	hsa-miR-3117-5p	CLIP-seq
MIRT940239	hsa-miR-3128	CLIP-seq
MIRT1978067	hsa-miR-3130-5p	CLIP-seq
MIRT1978068	hsa-miR-3143	CLIP-seq
MIRT940241	hsa-miR-3194-5p	CLIP-seq
MIRT1978069	hsa-miR-323-3p	CLIP-seq
MIRT940243	hsa-miR-338-3p	CLIP-seq
MIRT940245	hsa-miR-3613-3p	CLIP-seq
MIRT940246	hsa-miR-3619-5p	CLIP-seq
MIRT940247	hsa-miR-3655	CLIP-seq
MIRT2517440	hsa-miR-372	CLIP-seq
MIRT2517441	hsa-miR-373	CLIP-seq
MIRT940250	hsa-miR-382	CLIP-seq
MIRT940251	hsa-miR-3907	CLIP-seq
MIRT940252	hsa-miR-3942-3p	CLIP-seq
MIRT940253	hsa-miR-3972	CLIP-seq
MIRT940256	hsa-miR-4284	CLIP-seq
MIRT940257	hsa-miR-4310	CLIP-seq
MIRT940258	hsa-miR-4311	CLIP-seq
MIRT940259	hsa-miR-432	CLIP-seq
MIRT940260	hsa-miR-4326	CLIP-seq
MIRT940262	hsa-miR-4432	CLIP-seq
MIRT940263	hsa-miR-4444	CLIP-seq
MIRT1978071	hsa-miR-4482	CLIP-seq
MIRT940267	hsa-miR-4690-5p	CLIP-seq
MIRT940268	hsa-miR-4704-5p	CLIP-seq
MIRT940270	hsa-miR-4744	CLIP-seq
MIRT940271	hsa-miR-4775	CLIP-seq
MIRT1978072	hsa-miR-4804-3p	CLIP-seq
MIRT940272	hsa-miR-500a	CLIP-seq
MIRT940276	hsa-miR-513a-5p	CLIP-seq
MIRT940277	hsa-miR-519a	CLIP-seq
MIRT940278	hsa-miR-519d	CLIP-seq
MIRT2517442	hsa-miR-520a-3p	CLIP-seq
MIRT2517443	hsa-miR-520b	CLIP-seq
MIRT2517444	hsa-miR-520c-3p	CLIP-seq
MIRT2517445	hsa-miR-520d-3p	CLIP-seq
MIRT2517446	hsa-miR-520e	CLIP-seq
MIRT940279	hsa-miR-520g	CLIP-seq
MIRT940280	hsa-miR-522	CLIP-seq
MIRT1978073	hsa-miR-543	CLIP-seq
MIRT940281	hsa-miR-548o	CLIP-seq
MIRT940286	hsa-miR-569	CLIP-seq
MIRT2213625	hsa-miR-570	CLIP-seq
MIRT940287	hsa-miR-583	CLIP-seq
MIRT2517447	hsa-miR-590-3p	CLIP-seq
MIRT1978074	hsa-miR-634	CLIP-seq
MIRT940288	hsa-miR-636	CLIP-seq
MIRT940290	hsa-miR-676	CLIP-seq
MIRT940291	hsa-miR-761	CLIP-seq
MIRT940295	hsa-miR-93	CLIP-seq
MIRT940210	hsa-miR-105	CLIP-seq
MIRT940211	hsa-miR-106a	CLIP-seq
MIRT940212	hsa-miR-106b	CLIP-seq
MIRT940215	hsa-miR-1276	CLIP-seq
MIRT940216	hsa-miR-1282	CLIP-seq
MIRT940218	hsa-miR-1324	CLIP-seq
MIRT940219	hsa-miR-138	CLIP-seq
MIRT940220	hsa-miR-17	CLIP-seq
MIRT940223	hsa-miR-203	CLIP-seq
MIRT940224	hsa-miR-2053	CLIP-seq
MIRT940225	hsa-miR-20a	CLIP-seq
MIRT940226	hsa-miR-20b	CLIP-seq
MIRT940228	hsa-miR-2355-3p	CLIP-seq
MIRT940229	hsa-miR-23a	CLIP-seq
MIRT940230	hsa-miR-23b	CLIP-seq
MIRT940231	hsa-miR-23c	CLIP-seq
MIRT940232	hsa-miR-24	CLIP-seq
MIRT2517435	hsa-miR-302a	CLIP-seq
MIRT2517436	hsa-miR-302b	CLIP-seq
MIRT2517437	hsa-miR-302c	CLIP-seq
MIRT2517438	hsa-miR-302d	CLIP-seq
MIRT2517439	hsa-miR-302e	CLIP-seq
MIRT940237	hsa-miR-3117-5p	CLIP-seq
MIRT940239	hsa-miR-3128	CLIP-seq
MIRT1978068	hsa-miR-3143	CLIP-seq
MIRT940245	hsa-miR-3613-3p	CLIP-seq
MIRT940247	hsa-miR-3655	CLIP-seq
MIRT2517440	hsa-miR-372	CLIP-seq
MIRT2517441	hsa-miR-373	CLIP-seq
MIRT940251	hsa-miR-3907	CLIP-seq
MIRT940252	hsa-miR-3942-3p	CLIP-seq
MIRT940256	hsa-miR-4284	CLIP-seq
MIRT940258	hsa-miR-4311	CLIP-seq
MIRT940259	hsa-miR-432	CLIP-seq
MIRT940260	hsa-miR-4326	CLIP-seq
MIRT940262	hsa-miR-4432	CLIP-seq
MIRT940263	hsa-miR-4444	CLIP-seq
MIRT940268	hsa-miR-4704-5p	CLIP-seq
MIRT940270	hsa-miR-4744	CLIP-seq
MIRT940272	hsa-miR-500a	CLIP-seq
MIRT940277	hsa-miR-519a	CLIP-seq
MIRT940278	hsa-miR-519d	CLIP-seq
MIRT2517442	hsa-miR-520a-3p	CLIP-seq
MIRT2517443	hsa-miR-520b	CLIP-seq
MIRT2517444	hsa-miR-520c-3p	CLIP-seq
MIRT2517445	hsa-miR-520d-3p	CLIP-seq
MIRT2517446	hsa-miR-520e	CLIP-seq
MIRT940279	hsa-miR-520g	CLIP-seq
MIRT940280	hsa-miR-522	CLIP-seq
MIRT1978073	hsa-miR-543	CLIP-seq
MIRT940282	hsa-miR-548u	CLIP-seq
MIRT940286	hsa-miR-569	CLIP-seq
MIRT940287	hsa-miR-583	CLIP-seq
MIRT2517447	hsa-miR-590-3p	CLIP-seq
MIRT940288	hsa-miR-636	CLIP-seq
MIRT940290	hsa-miR-676	CLIP-seq
MIRT940295	hsa-miR-93	CLIP-seq

Show/Hide all(44)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001671	Function	ATPase activator activity	IDA	11896048
GO:0001671	Function	ATPase activator activity	TAS
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	10954706, 16919237, 22366786, 23414517, 25036637, 32814053, 33961781
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	10954706, 21231916
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	21231916
GO:0005829	Component	Cytosol	TAS
GO:0006457	Process	Protein folding	IBA
GO:0006457	Process	Protein folding	IDA	11896048
GO:0016020	Component	Membrane	HDA	19946888
GO:0030018	Component	Z disc	IDA	22366786
GO:0030018	Component	Z disc	IEA
GO:0030036	Process	Actin cytoskeleton organization	IEA
GO:0030198	Process	Extracellular matrix organization	IEA
GO:0030544	Function	Hsp70 protein binding	IEA
GO:0031072	Function	Heat shock protein binding	IDA	10954706
GO:0032880	Process	Regulation of protein localization	IMP	20889486
GO:0034504	Process	Protein localization to nucleus	IEA
GO:0042802	Function	Identical protein binding	IPI	22366786
GO:0044183	Function	Protein folding chaperone	IBA
GO:0045109	Process	Intermediate filament organization	IDA	10954706
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	10954706
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050877	Process	Nervous system process	IDA	11896048
GO:0051082	Function	Unfolded protein binding	IBA
GO:0051082	Function	Unfolded protein binding	IDA	21231916
GO:0051082	Function	Unfolded protein binding	IEA
GO:0051087	Function	Protein-folding chaperone binding	IBA
GO:0051087	Function	Protein-folding chaperone binding	IDA	11896048
GO:0051087	Function	Protein-folding chaperone binding	IPI	21231916
GO:0060710	Process	Chorio-allantoic fusion	IEA
GO:0060715	Process	Syncytiotrophoblast cell differentiation involved in labyrinthine layer development	IEA
GO:0060717	Process	Chorion development	IEA
GO:0090084	Process	Negative regulation of inclusion body assembly	IDA	21231916
GO:0090084	Process	Negative regulation of inclusion body assembly	IMP	20889486
GO:1900034	Process	Regulation of cellular response to heat	TAS

MIM	HGNC	e!Ensembl
611332	14888	ENSG00000105993

Protein

UniProt ID

O75190

Protein name

DnaJ homolog subfamily B member 6 (HHDJ1) (Heat shock protein J2) (HSJ-2) (MRJ) (MSJ-1)

Protein function

Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed:10954706, PubMed:28233300). Plays an indispensable role in the organization of KRT8/KRT18 fi

PDB

6U3R , 6U3S , 7JSQ , 7QBY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00226	DnaJ	3 → 66	DnaJ domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. Highest levels in testis and brain, and lower levels in heart, spleen, intestine, ovary, placenta, lung, kidney, pancreas, thymus, prostate, skeletal muscle, liver and leukocytes. In testis, expressed in germ cells in

Sequence

MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAK
KRDIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFE
DFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSSFDTGFTSFGSLGHGGLTSFSSTSF
GGSGMGNFKSISTSTKMVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGVADDDALAE
ERMRRGQNALPAQPAGLRPPKPPRPASLLRHAPHCLSEEEGEQDRPRAPGPWDPLASAAG
LKEGGKRKKQKQREESKKKKSTKGNH

Sequence length

326

Interactions

View interactions

	Reactome
			Regulation of HSF1-mediated heat shock response

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Limb-girdle muscular dystrophy	Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6)	rs869320702, rs869320701, rs575938861, rs387907046, rs387907047, rs149278319, rs387907150, rs869320700, rs759982570	N/A

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Dementia	Dementia	N/A	N/A	GWAS
Parkinson disease	parkinson disease, late-onset	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (49)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
AA amyloidosis	Inhibit	23904097, 32350108
alpha 1 Antitrypsin Deficiency	Associate	28819167
Arthritis Juvenile	Associate	17469159
Ataxia	Associate	28794355
Atherosclerosis	Associate	35795669
Breast Neoplasms	Associate	22710984, 28334900, 29954368
Bulbar Palsy Progressive	Associate	26205529
Carcinogenesis	Associate	28334900
Carcinoma Ductal	Inhibit	20522561
Coronary Artery Disease	Associate	35795669
Deglutition Disorders	Associate	29437287
Developmental Disabilities	Associate	30770860
Disease	Associate	28819167
Distal Myopathies	Associate	26205529, 29437287, 31955980
Distal myopathy Nonaka type	Associate	28794355
Encephalitis Japanese	Inhibit	31739611
Epstein Barr Virus Infections	Associate	16448567
Fibrosis	Associate	37894814
Genetic Diseases Inborn	Associate	22334415, 32268123, 37923706
Hereditary Myopathy with Early Respiratory Failure	Associate	28794355
Huntington Disease	Associate	36861837
Hypoxia	Associate	27625398
Inflammation	Associate	17469159
Low Back Pain	Associate	28794355
Lower Extremity Deformities Congenital	Associate	28794355
Lung Diseases	Associate	27625398
Malignant mesenchymal tumor	Associate	32889887
Marfan Syndrome	Associate	37894814
Multiple System Atrophy	Stimulate	34334418
Muscle Neoplasms	Associate	26847086
Muscular Diseases	Associate	22334415, 26205529, 26718575, 29437287, 31955980, 35931773
Muscular Dystrophies	Associate	29437287
Muscular Dystrophies Limb Girdle	Associate	22334415, 24594375, 28794355, 35931773
Muscular Dystrophy Limb Girdle Type 1D	Stimulate	24594375
Muscular Dystrophy Limb Girdle Type 1D	Associate	24594375, 26205529, 26847086, 29437287, 29869469, 30838352
Muscular Dystrophy Limb Girdle Type 1E	Associate	37923706
Myocardial Infarction	Associate	35795669
Myofibrillar Myopathy	Associate	26847086, 27618136, 39973468
Neoplasm Metastasis	Associate	25175595
Neoplasms	Associate	20522561, 22710984, 25175595, 32889887, 37894814
Nephrosis Lipoid	Associate	22334415
Nerve Degeneration	Associate	32268123, 37923706
Neuronal Ceroid Lipofuscinoses	Associate	35506243
Obesity	Associate	28207535
Ovarian Neoplasms	Associate	34075060, 35777713
Polyneuropathies	Associate	30770860
Post Infectious Disorders	Associate	16448567
Retinal Dystrophies	Associate	22334415
Supranuclear Palsy Progressive	Stimulate	34334418

DNAJB6 (DnaJ heat shock protein family (Hsp40) member B6)