Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10048
Gene name Gene Name - the full gene name approved by the HGNC.	RAN binding protein 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RANBP9
Synonyms (NCBI Gene) Gene synonyms aliases	BPM-L, BPM90, RANBPM, RanBP7
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p23
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to

Show/Hide all(244)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027298	hsa-miR-101-3p	Sequencing	20371350
MIRT048208	hsa-miR-196a-5p	CLASH	23622248
MIRT053411	hsa-miR-591	Microarray	23807165
MIRT1289709	hsa-miR-101	CLIP-seq
MIRT1289710	hsa-miR-1200	CLIP-seq
MIRT1289711	hsa-miR-1278	CLIP-seq
MIRT1289712	hsa-miR-1297	CLIP-seq
MIRT1289713	hsa-miR-1323	CLIP-seq
MIRT1289714	hsa-miR-137	CLIP-seq
MIRT1289715	hsa-miR-144	CLIP-seq
MIRT1289716	hsa-miR-150	CLIP-seq
MIRT1289717	hsa-miR-214	CLIP-seq
MIRT1289718	hsa-miR-25	CLIP-seq
MIRT1289719	hsa-miR-26a	CLIP-seq
MIRT1289720	hsa-miR-26b	CLIP-seq
MIRT1289721	hsa-miR-3065-5p	CLIP-seq
MIRT1289722	hsa-miR-3074-3p	CLIP-seq
MIRT1289723	hsa-miR-3177-5p	CLIP-seq
MIRT1289724	hsa-miR-3199	CLIP-seq
MIRT1289725	hsa-miR-32	CLIP-seq
MIRT1289726	hsa-miR-3202	CLIP-seq
MIRT1289727	hsa-miR-34c-3p	CLIP-seq
MIRT1289728	hsa-miR-3616-5p	CLIP-seq
MIRT1289729	hsa-miR-3619-5p	CLIP-seq
MIRT1289730	hsa-miR-363	CLIP-seq
MIRT1289731	hsa-miR-3647-5p	CLIP-seq
MIRT1289732	hsa-miR-3652	CLIP-seq
MIRT1289733	hsa-miR-3662	CLIP-seq
MIRT1289734	hsa-miR-3663-5p	CLIP-seq
MIRT1289735	hsa-miR-367	CLIP-seq
MIRT1289736	hsa-miR-3671	CLIP-seq
MIRT1289737	hsa-miR-4291	CLIP-seq
MIRT1289738	hsa-miR-4324	CLIP-seq
MIRT1289739	hsa-miR-4430	CLIP-seq
MIRT1289740	hsa-miR-4447	CLIP-seq
MIRT1289741	hsa-miR-4465	CLIP-seq
MIRT1289742	hsa-miR-4472	CLIP-seq
MIRT1289743	hsa-miR-4481	CLIP-seq
MIRT1289744	hsa-miR-4487	CLIP-seq
MIRT1289745	hsa-miR-4503	CLIP-seq
MIRT1289746	hsa-miR-4505	CLIP-seq
MIRT1289747	hsa-miR-4533	CLIP-seq
MIRT1289748	hsa-miR-4643	CLIP-seq
MIRT1289749	hsa-miR-466	CLIP-seq
MIRT1289750	hsa-miR-4670-3p	CLIP-seq
MIRT1289751	hsa-miR-4694-3p	CLIP-seq
MIRT1289752	hsa-miR-4713-5p	CLIP-seq
MIRT1289753	hsa-miR-4716-5p	CLIP-seq
MIRT1289754	hsa-miR-4729	CLIP-seq
MIRT1289755	hsa-miR-4745-5p	CLIP-seq
MIRT1289756	hsa-miR-4762-5p	CLIP-seq
MIRT1289757	hsa-miR-4789-3p	CLIP-seq
MIRT1289758	hsa-miR-4799-5p	CLIP-seq
MIRT1289759	hsa-miR-495	CLIP-seq
MIRT1289760	hsa-miR-496	CLIP-seq
MIRT1289761	hsa-miR-498	CLIP-seq
MIRT1289762	hsa-miR-508-3p	CLIP-seq
MIRT1289763	hsa-miR-512-5p	CLIP-seq
MIRT1289764	hsa-miR-513a-3p	CLIP-seq
MIRT1289765	hsa-miR-520d-5p	CLIP-seq
MIRT1289766	hsa-miR-524-5p	CLIP-seq
MIRT1289767	hsa-miR-532-3p	CLIP-seq
MIRT1289768	hsa-miR-544b	CLIP-seq
MIRT1289769	hsa-miR-548c-3p	CLIP-seq
MIRT1289770	hsa-miR-548o	CLIP-seq
MIRT1289771	hsa-miR-562	CLIP-seq
MIRT1289772	hsa-miR-573	CLIP-seq
MIRT1289773	hsa-miR-582-5p	CLIP-seq
MIRT1289774	hsa-miR-601	CLIP-seq
MIRT1289775	hsa-miR-606	CLIP-seq
MIRT1289776	hsa-miR-607	CLIP-seq
MIRT1289777	hsa-miR-761	CLIP-seq
MIRT1289778	hsa-miR-922	CLIP-seq
MIRT1289779	hsa-miR-92a	CLIP-seq
MIRT1289780	hsa-miR-92b	CLIP-seq
MIRT1289781	hsa-miR-934	CLIP-seq
MIRT1289782	hsa-miR-944	CLIP-seq
MIRT1289711	hsa-miR-1278	CLIP-seq
MIRT1289714	hsa-miR-137	CLIP-seq
MIRT1289716	hsa-miR-150	CLIP-seq
MIRT1289718	hsa-miR-25	CLIP-seq
MIRT1289721	hsa-miR-3065-5p	CLIP-seq
MIRT1289722	hsa-miR-3074-3p	CLIP-seq
MIRT2086057	hsa-miR-3183	CLIP-seq
MIRT1289724	hsa-miR-3199	CLIP-seq
MIRT1289725	hsa-miR-32	CLIP-seq
MIRT1289727	hsa-miR-34c-3p	CLIP-seq
MIRT2086058	hsa-miR-361-3p	CLIP-seq
MIRT1289728	hsa-miR-3616-5p	CLIP-seq
MIRT1289730	hsa-miR-363	CLIP-seq
MIRT1289731	hsa-miR-3647-5p	CLIP-seq
MIRT2086059	hsa-miR-3667-3p	CLIP-seq
MIRT1289735	hsa-miR-367	CLIP-seq
MIRT1289750	hsa-miR-4670-3p	CLIP-seq
MIRT1289752	hsa-miR-4713-5p	CLIP-seq
MIRT2086060	hsa-miR-4723-3p	CLIP-seq
MIRT1289759	hsa-miR-495	CLIP-seq
MIRT2086061	hsa-miR-499-3p	CLIP-seq
MIRT2086062	hsa-miR-499a-3p	CLIP-seq
MIRT1289762	hsa-miR-508-3p	CLIP-seq
MIRT1289767	hsa-miR-532-3p	CLIP-seq
MIRT1289771	hsa-miR-562	CLIP-seq
MIRT1289772	hsa-miR-573	CLIP-seq
MIRT2086063	hsa-miR-579	CLIP-seq
MIRT1289779	hsa-miR-92a	CLIP-seq
MIRT1289780	hsa-miR-92b	CLIP-seq
MIRT1289782	hsa-miR-944	CLIP-seq
MIRT1289709	hsa-miR-101	CLIP-seq
MIRT1289710	hsa-miR-1200	CLIP-seq
MIRT2311298	hsa-miR-1283	CLIP-seq
MIRT1289712	hsa-miR-1297	CLIP-seq
MIRT1289714	hsa-miR-137	CLIP-seq
MIRT1289715	hsa-miR-144	CLIP-seq
MIRT2311299	hsa-miR-200b	CLIP-seq
MIRT2311300	hsa-miR-200c	CLIP-seq
MIRT2311301	hsa-miR-2054	CLIP-seq
MIRT1289717	hsa-miR-214	CLIP-seq
MIRT1289718	hsa-miR-25	CLIP-seq
MIRT1289719	hsa-miR-26a	CLIP-seq
MIRT1289720	hsa-miR-26b	CLIP-seq
MIRT1289721	hsa-miR-3065-5p	CLIP-seq
MIRT1289722	hsa-miR-3074-3p	CLIP-seq
MIRT2311302	hsa-miR-3137	CLIP-seq
MIRT1289725	hsa-miR-32	CLIP-seq
MIRT1289727	hsa-miR-34c-3p	CLIP-seq
MIRT2311303	hsa-miR-3618	CLIP-seq
MIRT1289729	hsa-miR-3619-5p	CLIP-seq
MIRT1289730	hsa-miR-363	CLIP-seq
MIRT1289734	hsa-miR-3663-5p	CLIP-seq
MIRT1289735	hsa-miR-367	CLIP-seq
MIRT1289736	hsa-miR-3671	CLIP-seq
MIRT2311304	hsa-miR-369-3p	CLIP-seq
MIRT2311305	hsa-miR-374a	CLIP-seq
MIRT2311306	hsa-miR-374b	CLIP-seq
MIRT2311307	hsa-miR-374c	CLIP-seq
MIRT2311308	hsa-miR-380	CLIP-seq
MIRT2311309	hsa-miR-429	CLIP-seq
MIRT1289737	hsa-miR-4291	CLIP-seq
MIRT1289738	hsa-miR-4324	CLIP-seq
MIRT1289741	hsa-miR-4465	CLIP-seq
MIRT1289744	hsa-miR-4487	CLIP-seq
MIRT2311310	hsa-miR-452	CLIP-seq
MIRT1289748	hsa-miR-4643	CLIP-seq
MIRT2311311	hsa-miR-4659a-3p	CLIP-seq
MIRT2311312	hsa-miR-4659b-3p	CLIP-seq
MIRT1289749	hsa-miR-466	CLIP-seq
MIRT2311313	hsa-miR-4676-3p	CLIP-seq
MIRT2311314	hsa-miR-4703-3p	CLIP-seq
MIRT2311315	hsa-miR-4709-5p	CLIP-seq
MIRT1289753	hsa-miR-4716-5p	CLIP-seq
MIRT1289756	hsa-miR-4762-5p	CLIP-seq
MIRT1289757	hsa-miR-4789-3p	CLIP-seq
MIRT2311316	hsa-miR-491-3p	CLIP-seq
MIRT1289759	hsa-miR-495	CLIP-seq
MIRT1289760	hsa-miR-496	CLIP-seq
MIRT1289761	hsa-miR-498	CLIP-seq
MIRT1289762	hsa-miR-508-3p	CLIP-seq
MIRT1289763	hsa-miR-512-5p	CLIP-seq
MIRT1289764	hsa-miR-513a-3p	CLIP-seq
MIRT1289768	hsa-miR-544b	CLIP-seq
MIRT2311317	hsa-miR-548g	CLIP-seq
MIRT1289771	hsa-miR-562	CLIP-seq
MIRT1289773	hsa-miR-582-5p	CLIP-seq
MIRT2311318	hsa-miR-586	CLIP-seq
MIRT1289774	hsa-miR-601	CLIP-seq
MIRT1289776	hsa-miR-607	CLIP-seq
MIRT2311319	hsa-miR-627	CLIP-seq
MIRT2311320	hsa-miR-655	CLIP-seq
MIRT1289777	hsa-miR-761	CLIP-seq
MIRT1289778	hsa-miR-922	CLIP-seq
MIRT2311321	hsa-miR-924	CLIP-seq
MIRT1289779	hsa-miR-92a	CLIP-seq
MIRT1289780	hsa-miR-92b	CLIP-seq
MIRT1289781	hsa-miR-934	CLIP-seq
MIRT1289782	hsa-miR-944	CLIP-seq
MIRT1289721	hsa-miR-3065-5p	CLIP-seq
MIRT1289759	hsa-miR-495	CLIP-seq
MIRT1289762	hsa-miR-508-3p	CLIP-seq
MIRT1289771	hsa-miR-562	CLIP-seq
MIRT1289709	hsa-miR-101	CLIP-seq
MIRT1289710	hsa-miR-1200	CLIP-seq
MIRT2607666	hsa-miR-1290	CLIP-seq
MIRT1289712	hsa-miR-1297	CLIP-seq
MIRT1289715	hsa-miR-144	CLIP-seq
MIRT1289719	hsa-miR-26a	CLIP-seq
MIRT1289720	hsa-miR-26b	CLIP-seq
MIRT1289721	hsa-miR-3065-5p	CLIP-seq
MIRT2086057	hsa-miR-3183	CLIP-seq
MIRT2607667	hsa-miR-331-5p	CLIP-seq
MIRT2086058	hsa-miR-361-3p	CLIP-seq
MIRT2086059	hsa-miR-3667-3p	CLIP-seq
MIRT2607668	hsa-miR-3714	CLIP-seq
MIRT1289738	hsa-miR-4324	CLIP-seq
MIRT1289741	hsa-miR-4465	CLIP-seq
MIRT1289748	hsa-miR-4643	CLIP-seq
MIRT1289749	hsa-miR-466	CLIP-seq
MIRT2607669	hsa-miR-4711-5p	CLIP-seq
MIRT2086060	hsa-miR-4723-3p	CLIP-seq
MIRT1289757	hsa-miR-4789-3p	CLIP-seq
MIRT1289759	hsa-miR-495	CLIP-seq
MIRT1289760	hsa-miR-496	CLIP-seq
MIRT1289761	hsa-miR-498	CLIP-seq
MIRT1289762	hsa-miR-508-3p	CLIP-seq
MIRT1289763	hsa-miR-512-5p	CLIP-seq
MIRT1289768	hsa-miR-544b	CLIP-seq
MIRT1289769	hsa-miR-548c-3p	CLIP-seq
MIRT1289771	hsa-miR-562	CLIP-seq
MIRT2086063	hsa-miR-579	CLIP-seq
MIRT1289773	hsa-miR-582-5p	CLIP-seq
MIRT2607670	hsa-miR-659	CLIP-seq
MIRT2607671	hsa-miR-940	CLIP-seq
MIRT1289709	hsa-miR-101	CLIP-seq
MIRT1289710	hsa-miR-1200	CLIP-seq
MIRT2607666	hsa-miR-1290	CLIP-seq
MIRT1289712	hsa-miR-1297	CLIP-seq
MIRT1289715	hsa-miR-144	CLIP-seq
MIRT1289719	hsa-miR-26a	CLIP-seq
MIRT1289720	hsa-miR-26b	CLIP-seq
MIRT1289721	hsa-miR-3065-5p	CLIP-seq
MIRT2086057	hsa-miR-3183	CLIP-seq
MIRT2607667	hsa-miR-331-5p	CLIP-seq
MIRT2086058	hsa-miR-361-3p	CLIP-seq
MIRT1289733	hsa-miR-3662	CLIP-seq
MIRT2086059	hsa-miR-3667-3p	CLIP-seq
MIRT2607668	hsa-miR-3714	CLIP-seq
MIRT1289738	hsa-miR-4324	CLIP-seq
MIRT1289741	hsa-miR-4465	CLIP-seq
MIRT1289748	hsa-miR-4643	CLIP-seq
MIRT2311311	hsa-miR-4659a-3p	CLIP-seq
MIRT2311312	hsa-miR-4659b-3p	CLIP-seq
MIRT1289749	hsa-miR-466	CLIP-seq
MIRT2086060	hsa-miR-4723-3p	CLIP-seq
MIRT1289757	hsa-miR-4789-3p	CLIP-seq
MIRT1289759	hsa-miR-495	CLIP-seq
MIRT1289760	hsa-miR-496	CLIP-seq
MIRT1289761	hsa-miR-498	CLIP-seq
MIRT1289762	hsa-miR-508-3p	CLIP-seq
MIRT1289763	hsa-miR-512-5p	CLIP-seq
MIRT1289768	hsa-miR-544b	CLIP-seq
MIRT1289769	hsa-miR-548c-3p	CLIP-seq
MIRT1289771	hsa-miR-562	CLIP-seq
MIRT1289773	hsa-miR-582-5p	CLIP-seq
MIRT2607670	hsa-miR-659	CLIP-seq
MIRT2607671	hsa-miR-940	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000151	Component	Ubiquitin ligase complex	IDA	29911972
GO:0000165	Process	MAPK cascade	TAS
GO:0005515	Function	Protein binding	IPI	12220523, 12421467, 12812986, 14500717, 15381419, 16478441, 18555800, 18710924, 19788913, 20580816, 21382349, 23840749, 31413325, 32814053
GO:0005634	Component	Nucleus	IDA	12220523, 15381419, 17467196
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	15381419, 17467196, 24143168
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005875	Component	Microtubule associated complex	TAS	9817760
GO:0005886	Component	Plasma membrane	IEA
GO:0007010	Process	Cytoskeleton organization	IBA	21873635
GO:0007020	Process	Microtubule nucleation	NAS	12220523
GO:0007166	Process	Cell surface receptor signaling pathway	IBA	21873635
GO:0007411	Process	Axon guidance	TAS
GO:0016604	Component	Nuclear body	IDA
GO:0019899	Function	Enzyme binding	IPI	17087506
GO:0065003	Process	Protein-containing complex assembly	TAS	9817760
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IMP	23118896
GO:1902993	Process	Positive regulation of amyloid precursor protein catabolic process	ISS

MIM	HGNC	e!Ensembl
603854	13727	ENSG00000010017

Protein

UniProt ID

Q96S59

Protein name

Ran-binding protein 9 (RanBP9) (BPM-L) (BPM90) (Ran-binding protein M) (RanBPM) (RanBP7)

Protein function

May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement (PubMed:18710924). Core component of th

PDB

5JI7 , 5JI9 , 5JIU , 7NSC

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00622	SPRY	214 → 332	SPRY domain	Family
PF08513	LisH	367 → 393	LisH	Domain
PF10607	CLTH	403 → 711	CTLH/CRA C-terminal to LisH motif domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the

Sequence

MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL
GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT
PALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYIGL
SQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVN
MNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHS
LGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGD
REGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMG
EAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRP
FSSPSMSPSHGMNIHNLASGKGSTAHFSGFESCSNGVISNKAHQSYCHSNKHQSSNLNVP
ELNSINMSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEV
DSSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRDCGKNTANKKMLKDAFSLLAYSDP
WNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGIGSCA
FATVEDYLH

Sequence length

729

Interactions

View interactions

	Reactome
			L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	25482375

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Breast cancer	Breast cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	12421467
Breast Neoplasms	Stimulate	34875851
Carcinogenesis	Associate	23118896
HAIR AN syndrome	Associate	26943034
Inflammation	Associate	12421467
Larva Migrans	Associate	26919101
Lung Neoplasms	Associate	26943034
Neoplasms	Associate	12421467, 34875851
Neurodegenerative Diseases	Associate	32217127
Prostatic Neoplasms	Associate	12361945

RANBP9 (RAN binding protein 9)