SH2D3A (SH2 domain containing 3A)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein
Entrez ID 10045
Gene name SH2 domain containing 3A
Gene symbol SH2D3A
Synonyms (NCBI Gene)
NSP1
Chromosome 19
Chromosome location 19p13.3
miRNA miRNA information provided by mirtarbase database.
9
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (9)
miRTarBase ID miRNA Experiments Reference
MIRT016816 hsa-miR-335-5p Microarray 18185580
MIRT022136 hsa-miR-124-3p Microarray 18668037
MIRT1344237 hsa-miR-143 CLIP-seq
MIRT1344238 hsa-miR-3674 CLIP-seq
MIRT1344239 hsa-miR-4328 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (5)
GO ID Ontology Definition Evidence Reference
GO:0001784 Function Phosphotyrosine residue binding IEA
GO:0005085 Function Guanyl-nucleotide exchange factor activity IEA
GO:0005515 Function Protein binding IPI 24658140, 31980649
GO:0007254 Process JNK cascade TAS 10187783
GO:0007264 Process Small GTPase-mediated signal transduction IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
604721 16885 ENSG00000125731
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BRG2
Protein name SH2 domain-containing protein 3A (Novel SH2-containing protein 1)
Protein function May play a role in JNK activation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00017 SH2 15 → 95 SH2 domain Domain
Tissue specificity TISSUE SPECIFICITY: Weakly expressed in placenta, fetal kidney, fetal lung, adult pancreas, adult kidney and adult lung. {ECO:0000269|PubMed:10187783}.
Sequence 
MQVPQDGEDLAGQPWYHGLLSRQKAEALLQQNGDFLVRASGSRGGNPVISCRWRGSALHF
EVFRVALRPRPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSRPVTWQGPL
RRSFSEDTLMDGPARIEPLRARKWSNSQPADLAHMGRSREDPAGMEASTMPISALPRTSS
DPVLLKAPAPLGTVADSLRASDGQLQAKAPTKPPRTPSFELPDASERPPTYCELVPRVPS
VQGTSPSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPHDAPSCLLGPQNRPLEPQ
VLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHHLR
LELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPMVRL
LEGEEVAGPLDESCERLLRTLHGARHMVRDAPKFRKVAAQRLRGFRPNPELREALTTGFV
RRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR
Sequence length 576
Interactions View interactions