Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10038
Gene name Gene Name - the full gene name approved by the HGNC.	Poly(ADP-ribose) polymerase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PARP2
Synonyms (NCBI Gene) Gene synonyms aliases	ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transfer

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miRTarBase ID	miRNA	Experiments	Reference
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT701062	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT701061	hsa-miR-548ag	HITS-CLIP	23313552
MIRT701060	hsa-miR-548ai	HITS-CLIP	23313552
MIRT701059	hsa-miR-548ba	HITS-CLIP	23313552
MIRT701058	hsa-miR-570-5p	HITS-CLIP	23313552
MIRT701057	hsa-miR-624-3p	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT701056	hsa-miR-4457	HITS-CLIP	23313552
MIRT701055	hsa-miR-125b-2-3p	HITS-CLIP	23313552
MIRT701054	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT701053	hsa-miR-7854-3p	HITS-CLIP	23313552
MIRT701052	hsa-miR-6134	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT701050	hsa-miR-6894-5p	HITS-CLIP	23313552
MIRT701051	hsa-miR-1233-5p	HITS-CLIP	23313552
MIRT701049	hsa-miR-6778-5p	HITS-CLIP	23313552
MIRT701048	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT701047	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT701046	hsa-miR-3122	HITS-CLIP	23313552
MIRT701045	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT701044	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687284	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT676251	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT676250	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT676249	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT676248	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT676247	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT676246	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT676245	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT676244	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT676242	hsa-miR-4330	HITS-CLIP	23824327
MIRT676243	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT676241	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT676240	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT676239	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT676238	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT676237	hsa-miR-6131	HITS-CLIP	23824327
MIRT676236	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT676235	hsa-miR-548s	HITS-CLIP	23824327
MIRT676234	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT676233	hsa-miR-588	HITS-CLIP	23824327
MIRT676232	hsa-miR-4435	HITS-CLIP	23824327
MIRT676231	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT676230	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT676229	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT632636	hsa-miR-3677-5p	HITS-CLIP	23824327
MIRT632635	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT632634	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT632633	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT632632	hsa-miR-4284	HITS-CLIP	23824327
MIRT632631	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT632630	hsa-miR-4505	HITS-CLIP	23824327
MIRT632629	hsa-miR-5787	HITS-CLIP	23824327
MIRT632628	hsa-miR-6772-5p	HITS-CLIP	23824327
MIRT632627	hsa-miR-4455	HITS-CLIP	23824327
MIRT632626	hsa-miR-609	HITS-CLIP	23824327
MIRT632625	hsa-miR-6073	HITS-CLIP	23824327
MIRT632624	hsa-miR-142-3p	HITS-CLIP	23824327
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT526108	hsa-miR-5692a	PAR-CLIP	21572407
MIRT526107	hsa-miR-577	PAR-CLIP	21572407
MIRT541640	hsa-miR-4432	PAR-CLIP	21572407
MIRT541639	hsa-miR-3664-5p	PAR-CLIP	21572407
MIRT541638	hsa-miR-589-3p	PAR-CLIP	21572407
MIRT541637	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT541636	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT541635	hsa-miR-1285-3p	PAR-CLIP	21572407
MIRT541634	hsa-miR-3187-5p	PAR-CLIP	21572407
MIRT541633	hsa-miR-5189-5p	PAR-CLIP	21572407
MIRT541632	hsa-miR-612	PAR-CLIP	21572407
MIRT541631	hsa-miR-6860	PAR-CLIP	21572407
MIRT541630	hsa-miR-3120-5p	PAR-CLIP	21572407
MIRT541629	hsa-miR-4522	PAR-CLIP	21572407
MIRT541628	hsa-miR-661	PAR-CLIP	21572407
MIRT541627	hsa-miR-196a-3p	PAR-CLIP	21572407
MIRT541625	hsa-miR-6888-3p	PAR-CLIP	21572407
MIRT541626	hsa-miR-6510-3p	PAR-CLIP	21572407
MIRT526109	hsa-miR-548m	PAR-CLIP	22012620
MIRT526108	hsa-miR-5692a	PAR-CLIP	22012620
MIRT526107	hsa-miR-577	PAR-CLIP	22012620
MIRT526105	hsa-miR-6815-5p	PAR-CLIP	22012620
MIRT526106	hsa-miR-6865-5p	PAR-CLIP	22012620
MIRT526109	hsa-miR-548m	PAR-CLIP	27292025
MIRT526108	hsa-miR-5692a	PAR-CLIP	27292025
MIRT526105	hsa-miR-6815-5p	PAR-CLIP	27292025
MIRT526106	hsa-miR-6865-5p	PAR-CLIP	27292025
MIRT733647	hsa-miR-149-5p	qRT-PCR	34051087
MIRT733647	hsa-miR-149-5p	qRT-PCR	34051087
MIRT733647	hsa-miR-149-5p	qRT-PCR	34051087
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT701062	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT701061	hsa-miR-548ag	HITS-CLIP	23313552
MIRT701060	hsa-miR-548ai	HITS-CLIP	23313552
MIRT701059	hsa-miR-548ba	HITS-CLIP	23313552
MIRT701058	hsa-miR-570-5p	HITS-CLIP	23313552
MIRT701057	hsa-miR-624-3p	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT701056	hsa-miR-4457	HITS-CLIP	23313552
MIRT701055	hsa-miR-125b-2-3p	HITS-CLIP	23313552
MIRT701054	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT701053	hsa-miR-7854-3p	HITS-CLIP	23313552
MIRT701052	hsa-miR-6134	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT701050	hsa-miR-6894-5p	HITS-CLIP	23313552
MIRT701051	hsa-miR-1233-5p	HITS-CLIP	23313552
MIRT701049	hsa-miR-6778-5p	HITS-CLIP	23313552
MIRT701048	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT701047	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT701046	hsa-miR-3122	HITS-CLIP	23313552
MIRT701045	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT701044	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687284	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT676251	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT676250	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT676249	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT676248	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT676247	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT676246	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT676245	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT676244	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT676242	hsa-miR-4330	HITS-CLIP	23824327
MIRT676243	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT676241	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT676240	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT676239	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT676238	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT676237	hsa-miR-6131	HITS-CLIP	23824327
MIRT676236	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT676235	hsa-miR-548s	HITS-CLIP	23824327
MIRT676234	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT676233	hsa-miR-588	HITS-CLIP	23824327
MIRT676232	hsa-miR-4435	HITS-CLIP	23824327
MIRT676231	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT676230	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT676229	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT632636	hsa-miR-3677-5p	HITS-CLIP	23824327
MIRT632635	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT632634	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT632633	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT632632	hsa-miR-4284	HITS-CLIP	23824327
MIRT632631	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT632630	hsa-miR-4505	HITS-CLIP	23824327
MIRT632629	hsa-miR-5787	HITS-CLIP	23824327
MIRT632628	hsa-miR-6772-5p	HITS-CLIP	23824327
MIRT632627	hsa-miR-4455	HITS-CLIP	23824327
MIRT632626	hsa-miR-609	HITS-CLIP	23824327
MIRT632625	hsa-miR-6073	HITS-CLIP	23824327
MIRT632624	hsa-miR-142-3p	HITS-CLIP	23824327
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT526108	hsa-miR-5692a	PAR-CLIP	21572407
MIRT526107	hsa-miR-577	PAR-CLIP	21572407
MIRT541640	hsa-miR-4432	PAR-CLIP	21572407
MIRT541639	hsa-miR-3664-5p	PAR-CLIP	21572407
MIRT541638	hsa-miR-589-3p	PAR-CLIP	21572407
MIRT541637	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT541636	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT541635	hsa-miR-1285-3p	PAR-CLIP	21572407
MIRT541634	hsa-miR-3187-5p	PAR-CLIP	21572407
MIRT541633	hsa-miR-5189-5p	PAR-CLIP	21572407
MIRT541632	hsa-miR-612	PAR-CLIP	21572407
MIRT541631	hsa-miR-6860	PAR-CLIP	21572407
MIRT541630	hsa-miR-3120-5p	PAR-CLIP	21572407
MIRT541629	hsa-miR-4522	PAR-CLIP	21572407
MIRT541628	hsa-miR-661	PAR-CLIP	21572407
MIRT541627	hsa-miR-196a-3p	PAR-CLIP	21572407
MIRT541625	hsa-miR-6888-3p	PAR-CLIP	21572407
MIRT541626	hsa-miR-6510-3p	PAR-CLIP	21572407
MIRT526109	hsa-miR-548m	PAR-CLIP	22012620
MIRT526108	hsa-miR-5692a	PAR-CLIP	22012620
MIRT526107	hsa-miR-577	PAR-CLIP	22012620
MIRT526105	hsa-miR-6815-5p	PAR-CLIP	22012620
MIRT526106	hsa-miR-6865-5p	PAR-CLIP	22012620
MIRT755775	hsa-miR-4796-5p	Luciferase reporter assay, Western blotting, qRT-PCR, in vitro cullelar assays, GFP reporter assay	37460775
MIRT2290139	hsa-miR-141	CLIP-seq
MIRT2290140	hsa-miR-200a	CLIP-seq
MIRT2290141	hsa-miR-3163	CLIP-seq
MIRT2290142	hsa-miR-4719	CLIP-seq
MIRT2290143	hsa-miR-513b	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003950	Function	NAD+ ADP-ribosyltransferase activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	21812934, 27067600, 28190768
GO:0005654	Component	Nucleoplasm	IDA	15615785
GO:0005730	Component	Nucleolus	IBA	21873635
GO:0005730	Component	Nucleolus	IDA	15615785
GO:0006281	Process	DNA repair	TAS	7260241
GO:0006284	Process	Base-excision repair	IEA
GO:0006302	Process	Double-strand break repair	IBA	21873635
GO:0006471	Process	Protein ADP-ribosylation	TAS	7260241
GO:0018312	Process	Peptidyl-serine ADP-ribosylation	IDA	28190768
GO:0030592	Process	DNA ADP-ribosylation	IDA	27471034
GO:0061051	Process	Positive regulation of cell growth involved in cardiac muscle cell development	IEA
GO:0070212	Process	Protein poly-ADP-ribosylation	IBA	21873635
GO:0070212	Process	Protein poly-ADP-ribosylation	IDA	25043379
GO:0097191	Process	Extrinsic apoptotic signaling pathway	IEA
GO:0140294	Function	NAD DNA ADP-ribosyltransferase activity	IDA	27471034
GO:1901215	Process	Negative regulation of neuron death	IEA
GO:1990404	Function	Protein ADP-ribosylase activity	IBA	21873635
GO:1990404	Function	Protein ADP-ribosylase activity	IDA	25043379, 28190768

MIM	HGNC	e!Ensembl
607725	272	ENSG00000129484

Protein

UniProt ID

Q9UGN5

Protein name

Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (

Protein function

Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:25043379, PubMed:27471034, PubMed:30104678, PubMed:32028527, PubMed:32939087, PubMed:34108479, PubMed:3448652

PDB

3KCZ , 3KJD , 4PJV , 4TVJ , 4ZZX , 4ZZY , 5D5K , 5DSY , 6F1K , 6F5B , 6F5F , 6TX3 , 6USJ , 6X0L , 6X0M , 6X0N , 7AEO , 7R59 , 8HE8 , 8HKN , 8HKO , 8HKS , 8HLJ , 8HLQ , 8JNY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05406	WGR	115 → 195	WGR domain	Domain
PF02877	PARP_reg	232 → 362	Poly(ADP-ribose) polymerase, regulatory domain	Domain
PF00644	PARP	376 → 577	Poly(ADP-ribose) polymerase catalytic domain	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed, mainly in actively dividing tissues (PubMed:10364231). The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low

Sequence

MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD
RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN
QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF
LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE
LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME
ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ
HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL
HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK
NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP
ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW

Sequence length

583

Interactions

View interactions

	KEGG		Reactome
	Base excision repair Apoptosis		POLB-Dependent Long Patch Base Excision Repair HDR through MMEJ (alt-NHEJ) DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Lipodystrophy	Lipodystrophy	rs553668, rs766817317	21417348

Show/Hide Text Mining Associations (19)

Disease Name	Relationship Type	References
Associations from Text Mining
Azoospermia	Associate	19806447
Breast Neoplasms	Associate	25833211, 32207233, 32883354, 36315097
Carcinoma Hepatocellular	Associate	31340767
Cementoma	Associate	37995913
Colorectal Neoplasms	Associate	22194930, 28615517
Death	Inhibit	32360251
Diffuse Intrinsic Pontine Glioma	Associate	32229503
Drug Related Side Effects and Adverse Reactions	Inhibit	26505995
Heart Defects Congenital	Associate	26033827
Leukemia Myeloid Acute	Associate	32423430
Lymphoma Large B Cell Diffuse	Associate	35322192
Neoplasms	Associate	24072219, 31408463, 32207233, 34210965, 35945529, 36929572
Neoplasms	Inhibit	32360251
Ovarian Neoplasms	Associate	36063278
Prostatic Neoplasms	Associate	25111073
Recombinant chromosome 8 syndrome	Associate	36929572
Sarcoma	Associate	36929572
Stomach Neoplasms	Associate	35000531
Triple Negative Breast Neoplasms	Associate	34880209

PARP2 (poly(ADP-ribose) polymerase 2)