Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10038
Gene name Gene Name - the full gene name approved by the HGNC.	Poly(ADP-ribose) polymerase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PARP2
Synonyms (NCBI Gene) Gene synonyms aliases	ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transfer

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miRTarBase ID	miRNA	Experiments	Reference
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT701062	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT701061	hsa-miR-548ag	HITS-CLIP	23313552
MIRT701060	hsa-miR-548ai	HITS-CLIP	23313552
MIRT701059	hsa-miR-548ba	HITS-CLIP	23313552
MIRT701058	hsa-miR-570-5p	HITS-CLIP	23313552
MIRT701057	hsa-miR-624-3p	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT701056	hsa-miR-4457	HITS-CLIP	23313552
MIRT701055	hsa-miR-125b-2-3p	HITS-CLIP	23313552
MIRT701054	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT701053	hsa-miR-7854-3p	HITS-CLIP	23313552
MIRT701052	hsa-miR-6134	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT701050	hsa-miR-6894-5p	HITS-CLIP	23313552
MIRT701051	hsa-miR-1233-5p	HITS-CLIP	23313552
MIRT701049	hsa-miR-6778-5p	HITS-CLIP	23313552
MIRT701048	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT701047	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT701046	hsa-miR-3122	HITS-CLIP	23313552
MIRT701045	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT701044	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687284	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT676251	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT676250	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT676249	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT676248	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT676247	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT676246	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT676245	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT676244	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT676242	hsa-miR-4330	HITS-CLIP	23824327
MIRT676243	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT676241	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT676240	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT676239	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT676238	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT676237	hsa-miR-6131	HITS-CLIP	23824327
MIRT676236	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT676235	hsa-miR-548s	HITS-CLIP	23824327
MIRT676234	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT676233	hsa-miR-588	HITS-CLIP	23824327
MIRT676232	hsa-miR-4435	HITS-CLIP	23824327
MIRT676231	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT676230	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT676229	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT632636	hsa-miR-3677-5p	HITS-CLIP	23824327
MIRT632635	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT632634	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT632633	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT632632	hsa-miR-4284	HITS-CLIP	23824327
MIRT632631	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT632630	hsa-miR-4505	HITS-CLIP	23824327
MIRT632629	hsa-miR-5787	HITS-CLIP	23824327
MIRT632628	hsa-miR-6772-5p	HITS-CLIP	23824327
MIRT632627	hsa-miR-4455	HITS-CLIP	23824327
MIRT632626	hsa-miR-609	HITS-CLIP	23824327
MIRT632625	hsa-miR-6073	HITS-CLIP	23824327
MIRT632624	hsa-miR-142-3p	HITS-CLIP	23824327
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT526108	hsa-miR-5692a	PAR-CLIP	21572407
MIRT526107	hsa-miR-577	PAR-CLIP	21572407
MIRT541640	hsa-miR-4432	PAR-CLIP	21572407
MIRT541639	hsa-miR-3664-5p	PAR-CLIP	21572407
MIRT541638	hsa-miR-589-3p	PAR-CLIP	21572407
MIRT541637	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT541636	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT541635	hsa-miR-1285-3p	PAR-CLIP	21572407
MIRT541634	hsa-miR-3187-5p	PAR-CLIP	21572407
MIRT541633	hsa-miR-5189-5p	PAR-CLIP	21572407
MIRT541632	hsa-miR-612	PAR-CLIP	21572407
MIRT541631	hsa-miR-6860	PAR-CLIP	21572407
MIRT541630	hsa-miR-3120-5p	PAR-CLIP	21572407
MIRT541629	hsa-miR-4522	PAR-CLIP	21572407
MIRT541628	hsa-miR-661	PAR-CLIP	21572407
MIRT541627	hsa-miR-196a-3p	PAR-CLIP	21572407
MIRT541625	hsa-miR-6888-3p	PAR-CLIP	21572407
MIRT541626	hsa-miR-6510-3p	PAR-CLIP	21572407
MIRT526109	hsa-miR-548m	PAR-CLIP	22012620
MIRT526108	hsa-miR-5692a	PAR-CLIP	22012620
MIRT526107	hsa-miR-577	PAR-CLIP	22012620
MIRT526105	hsa-miR-6815-5p	PAR-CLIP	22012620
MIRT526106	hsa-miR-6865-5p	PAR-CLIP	22012620
MIRT526109	hsa-miR-548m	PAR-CLIP	27292025
MIRT526108	hsa-miR-5692a	PAR-CLIP	27292025
MIRT526105	hsa-miR-6815-5p	PAR-CLIP	27292025
MIRT526106	hsa-miR-6865-5p	PAR-CLIP	27292025
MIRT733647	hsa-miR-149-5p	qRT-PCR	34051087
MIRT733647	hsa-miR-149-5p	qRT-PCR	34051087
MIRT733647	hsa-miR-149-5p	qRT-PCR	34051087
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT701062	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT701061	hsa-miR-548ag	HITS-CLIP	23313552
MIRT701060	hsa-miR-548ai	HITS-CLIP	23313552
MIRT701059	hsa-miR-548ba	HITS-CLIP	23313552
MIRT701058	hsa-miR-570-5p	HITS-CLIP	23313552
MIRT701057	hsa-miR-624-3p	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT701056	hsa-miR-4457	HITS-CLIP	23313552
MIRT701055	hsa-miR-125b-2-3p	HITS-CLIP	23313552
MIRT701054	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT701053	hsa-miR-7854-3p	HITS-CLIP	23313552
MIRT701052	hsa-miR-6134	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT701050	hsa-miR-6894-5p	HITS-CLIP	23313552
MIRT701051	hsa-miR-1233-5p	HITS-CLIP	23313552
MIRT701049	hsa-miR-6778-5p	HITS-CLIP	23313552
MIRT701048	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT701047	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT701046	hsa-miR-3122	HITS-CLIP	23313552
MIRT701045	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT701044	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT687295	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT687294	hsa-miR-4323	HITS-CLIP	23313552
MIRT687293	hsa-miR-3943	HITS-CLIP	23313552
MIRT687292	hsa-miR-6769a-3p	HITS-CLIP	23313552
MIRT687291	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687290	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687289	hsa-miR-940	HITS-CLIP	23313552
MIRT687288	hsa-miR-3929	HITS-CLIP	23313552
MIRT687287	hsa-miR-4419b	HITS-CLIP	23313552
MIRT687286	hsa-miR-4478	HITS-CLIP	23313552
MIRT559971	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT559970	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT687285	hsa-miR-6736-3p	HITS-CLIP	23313552
MIRT687284	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT687283	hsa-miR-4267	HITS-CLIP	23313552
MIRT687282	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687281	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT687280	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT687279	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT687278	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687277	hsa-miR-4268	HITS-CLIP	23313552
MIRT687276	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT687275	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT687274	hsa-miR-665	HITS-CLIP	23313552
MIRT676251	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT676250	hsa-miR-1245b-3p	HITS-CLIP	23824327
MIRT676249	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT676248	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT676247	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT676246	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT676245	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT676244	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT676242	hsa-miR-4330	HITS-CLIP	23824327
MIRT676243	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT676241	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT676240	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT676239	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT676238	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT676237	hsa-miR-6131	HITS-CLIP	23824327
MIRT676236	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT676235	hsa-miR-548s	HITS-CLIP	23824327
MIRT676234	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT676233	hsa-miR-588	HITS-CLIP	23824327
MIRT676232	hsa-miR-4435	HITS-CLIP	23824327
MIRT676231	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT676230	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT676229	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT632636	hsa-miR-3677-5p	HITS-CLIP	23824327
MIRT632635	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT632634	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT632633	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT632632	hsa-miR-4284	HITS-CLIP	23824327
MIRT632631	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT632630	hsa-miR-4505	HITS-CLIP	23824327
MIRT632629	hsa-miR-5787	HITS-CLIP	23824327
MIRT632628	hsa-miR-6772-5p	HITS-CLIP	23824327
MIRT632627	hsa-miR-4455	HITS-CLIP	23824327
MIRT632626	hsa-miR-609	HITS-CLIP	23824327
MIRT632625	hsa-miR-6073	HITS-CLIP	23824327
MIRT632624	hsa-miR-142-3p	HITS-CLIP	23824327
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT559973	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT559972	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT559971	hsa-miR-3614-5p	PAR-CLIP	20371350
MIRT559970	hsa-miR-6500-3p	PAR-CLIP	20371350
MIRT559968	hsa-miR-4257	PAR-CLIP	20371350
MIRT559969	hsa-miR-1827	PAR-CLIP	20371350
MIRT559967	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT559965	hsa-miR-6086	PAR-CLIP	20371350
MIRT559966	hsa-miR-2467-3p	PAR-CLIP	20371350
MIRT559964	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT559963	hsa-miR-3612	PAR-CLIP	20371350
MIRT559962	hsa-miR-650	PAR-CLIP	20371350
MIRT559961	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT559960	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT526108	hsa-miR-5692a	PAR-CLIP	21572407
MIRT526107	hsa-miR-577	PAR-CLIP	21572407
MIRT541640	hsa-miR-4432	PAR-CLIP	21572407
MIRT541639	hsa-miR-3664-5p	PAR-CLIP	21572407
MIRT541638	hsa-miR-589-3p	PAR-CLIP	21572407
MIRT541637	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT541636	hsa-miR-939-3p	PAR-CLIP	21572407
MIRT541635	hsa-miR-1285-3p	PAR-CLIP	21572407
MIRT541634	hsa-miR-3187-5p	PAR-CLIP	21572407
MIRT541633	hsa-miR-5189-5p	PAR-CLIP	21572407
MIRT541632	hsa-miR-612	PAR-CLIP	21572407
MIRT541631	hsa-miR-6860	PAR-CLIP	21572407
MIRT541630	hsa-miR-3120-5p	PAR-CLIP	21572407
MIRT541629	hsa-miR-4522	PAR-CLIP	21572407
MIRT541628	hsa-miR-661	PAR-CLIP	21572407
MIRT541627	hsa-miR-196a-3p	PAR-CLIP	21572407
MIRT541625	hsa-miR-6888-3p	PAR-CLIP	21572407
MIRT541626	hsa-miR-6510-3p	PAR-CLIP	21572407
MIRT526109	hsa-miR-548m	PAR-CLIP	22012620
MIRT526108	hsa-miR-5692a	PAR-CLIP	22012620
MIRT526107	hsa-miR-577	PAR-CLIP	22012620
MIRT526105	hsa-miR-6815-5p	PAR-CLIP	22012620
MIRT526106	hsa-miR-6865-5p	PAR-CLIP	22012620
MIRT755775	hsa-miR-4796-5p	Luciferase reporter assay, Western blotting, qRT-PCR, in vitro cullelar assays, GFP reporter assay	37460775
MIRT2290139	hsa-miR-141	CLIP-seq
MIRT2290140	hsa-miR-200a	CLIP-seq
MIRT2290141	hsa-miR-3163	CLIP-seq
MIRT2290142	hsa-miR-4719	CLIP-seq
MIRT2290143	hsa-miR-513b	CLIP-seq

Show/Hide all(57)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IDA	32939087
GO:0003684	Function	Damaged DNA binding	IDA	34108479
GO:0003824	Function	Catalytic activity	IEA
GO:0003950	Function	NAD+ poly-ADP-ribosyltransferase activity	IBA
GO:0003950	Function	NAD+ poly-ADP-ribosyltransferase activity	IDA	30104678, 32028527, 32939087, 34732825, 34795260
GO:0003950	Function	NAD+ poly-ADP-ribosyltransferase activity	IEA
GO:0005515	Function	Protein binding	IPI	21812934, 27067600, 28190768, 32939087, 33961781
GO:0005634	Component	Nucleus	IDA	26704974
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA	15615785
GO:0005654	Component	Nucleoplasm	IEA
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	15615785
GO:0005730	Component	Nucleolus	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006281	Process	DNA repair	IDA	21211722, 30104678, 34108479
GO:0006281	Process	DNA repair	IDA	30104678, 34108479
GO:0006281	Process	DNA repair	IEA
GO:0006284	Process	Base-excision repair	IEA
GO:0006302	Process	Double-strand break repair	IBA
GO:0006974	Process	DNA damage response	IDA	34108479
GO:0006974	Process	DNA damage response	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0016779	Function	Nucleotidyltransferase activity	IEA
GO:0030592	Process	DNA ADP-ribosylation	IDA	27471034
GO:0030592	Process	DNA ADP-ribosylation	IEA
GO:0031491	Function	Nucleosome binding	IDA	32939087
GO:0031491	Function	Nucleosome binding	IEA
GO:0046697	Process	Decidualization	IEA
GO:0046697	Process	Decidualization	ISS
GO:0061051	Process	Positive regulation of cell growth involved in cardiac muscle cell development	IEA
GO:0070212	Process	Protein poly-ADP-ribosylation	IDA	25043379, 32939087
GO:0070213	Process	Protein auto-ADP-ribosylation	IDA	32939087, 34108479
GO:0070213	Process	Protein auto-ADP-ribosylation	IEA
GO:0071168	Process	Protein localization to chromatin	IDA	21211722
GO:0072572	Function	Poly-ADP-D-ribose binding	IDA	30104678
GO:0090649	Process	Response to oxygen-glucose deprivation	IEA
GO:0090734	Component	Site of DNA damage	IDA	30104678, 34108479
GO:0090734	Component	Site of DNA damage	IDA	26704974, 32939087
GO:0090734	Component	Site of DNA damage	IEA
GO:0097191	Process	Extrinsic apoptotic signaling pathway	IEA
GO:0110088	Process	Hippocampal neuron apoptotic process	IEA
GO:0140294	Function	NAD DNA ADP-ribosyltransferase activity	IDA	27471034
GO:0140294	Function	NAD DNA ADP-ribosyltransferase activity	IEA
GO:0140805	Function	NAD+-protein-serine ADP-ribosyltransferase activity	IDA	28190768, 32028527, 32939087, 34108479, 34732825, 34795260
GO:0140805	Function	NAD+-protein-serine ADP-ribosyltransferase activity	IEA
GO:0140806	Function	NAD+-protein-aspartate ADP-ribosyltransferase activity	IDA	25043379
GO:0140806	Function	NAD+-protein-aspartate ADP-ribosyltransferase activity	IEA
GO:0140807	Function	NAD+-protein-glutamate ADP-ribosyltransferase activity	IDA	25043379
GO:0140807	Function	NAD+-protein-glutamate ADP-ribosyltransferase activity	IEA
GO:0140861	Process	DNA repair-dependent chromatin remodeling	IDA	21211722
GO:0140861	Process	DNA repair-dependent chromatin remodeling	IDA	32939087
GO:0160004	Function	Poly-ADP-D-ribose modification-dependent protein binding	IDA	30104678
GO:1990404	Function	NAD+-protein mono-ADP-ribosyltransferase activity	IDA	25043379, 28190768, 32028527, 32939087, 34732825, 34795260

MIM	HGNC	e!Ensembl
607725	272	ENSG00000129484

Protein

UniProt ID

Q9UGN5

Protein name

Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (

Protein function

Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:25043379, PubMed:27471034, PubMed:30104678, PubMed:32028527, PubMed:32939087, PubMed:34108479, PubMed:3448652

PDB

3KCZ , 3KJD , 4PJV , 4TVJ , 4ZZX , 4ZZY , 5D5K , 5DSY , 6F1K , 6F5B , 6F5F , 6TX3 , 6USJ , 6X0L , 6X0M , 6X0N , 7AEO , 7R59 , 8HE8 , 8HKN , 8HKO , 8HKS , 8HLJ , 8HLQ , 8JNY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05406	WGR	115 → 195	WGR domain	Domain
PF02877	PARP_reg	232 → 362	Poly(ADP-ribose) polymerase, regulatory domain	Domain
PF00644	PARP	376 → 577	Poly(ADP-ribose) polymerase catalytic domain	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed, mainly in actively dividing tissues (PubMed:10364231). The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low

Sequence

MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD
RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN
QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF
LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE
LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME
ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ
HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL
HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK
NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP
ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW

Sequence length

583

Interactions

View interactions

	KEGG		Reactome
	Base excision repair Apoptosis		POLB-Dependent Long Patch Base Excision Repair HDR through MMEJ (alt-NHEJ) DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER

PARP2 (poly(ADP-ribose) polymerase 2)