Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10024
Gene name Gene Name - the full gene name approved by the HGNC.
Trophinin associated protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TROAP
Synonyms (NCBI Gene) Gene synonyms aliases
TASTIN
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024690 hsa-miR-215-5p Microarray 19074876
MIRT026899 hsa-miR-192-5p Microarray 19074876
MIRT042226 hsa-miR-484 CLASH 23622248
MIRT039703 hsa-miR-615-3p CLASH 23622248
MIRT734530 hsa-miR-519d-3p Luciferase reporter assay, Immunoprecipitaion (IP), qRT-PCR 32796815
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 9560222, 17360433, 19060904, 21516116, 23602568, 25416956, 26949739, 28514442, 30561431, 32296183
GO:0005737 Component Cytoplasm IEA
GO:0007155 Process Cell adhesion IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603872 12327 ENSG00000135451
Protein
UniProt ID Q12815
Protein name Tastin (Trophinin-assisting protein) (Trophinin-associated protein)
Protein function Could be involved with bystin and trophinin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation.
Family and domains
Tissue specificity TISSUE SPECIFICITY: Strong expression at implantation sites. Was exclusively localized to the apical side of the syncytiotrophoblast. Also found in macrophages.
Sequence
MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR
PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEF
VADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTH
RLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRT
SVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSH
DSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPM
PSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPH
SNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLN
ATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQE
QLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIP
ESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPP
CCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLT
AIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP
Sequence length 778
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Prostate cancer Prostate cancer Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 34139453
Breast Neoplasms Stimulate 31198787
Carcinoma Hepatocellular Associate 22997493
Carcinoma Hepatocellular Inhibit 29117881
Carcinoma Ovarian Epithelial Associate 24071868
Carcinoma Renal Cell Associate 34287099
Colorectal Neoplasms Associate 30021381, 32796815
Job Syndrome Associate 32541515
Leukemia Associate 36938721
Leukemia Myeloid Acute Associate 36938721