Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	100132406
Gene name Gene Name - the full gene name approved by the HGNC.	NBPF member 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NBPF10
Synonyms (NCBI Gene) Gene synonyms aliases	AB6, AG1, NBPF9
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q21.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the

Show/Hide all(111)

miRTarBase ID	miRNA	Experiments	Reference
MIRT541948	hsa-miR-8485	HITS-CLIP	21572407
MIRT707288	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT707287	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT541947	hsa-miR-603	HITS-CLIP	21572407
MIRT707286	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT707285	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707284	hsa-miR-3941	HITS-CLIP	21572407
MIRT707283	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT707282	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707281	hsa-miR-6516-3p	HITS-CLIP	21572407
MIRT707280	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT541948	hsa-miR-8485	HITS-CLIP	23824327
MIRT541947	hsa-miR-603	HITS-CLIP	23824327
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	23824327
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT541944	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT541948	hsa-miR-8485	HITS-CLIP	23824327
MIRT541947	hsa-miR-603	HITS-CLIP	23824327
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	23824327
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT541944	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT541948	hsa-miR-8485	HITS-CLIP	23824327
MIRT541947	hsa-miR-603	HITS-CLIP	23824327
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	23824327
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT541944	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT569651	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT569650	hsa-miR-641	PAR-CLIP	20371350
MIRT569649	hsa-miR-1324	PAR-CLIP	20371350
MIRT569648	hsa-miR-8060	PAR-CLIP	20371350
MIRT569647	hsa-miR-1250-3p	PAR-CLIP	20371350
MIRT569646	hsa-miR-549a	PAR-CLIP	20371350
MIRT569645	hsa-miR-7154-5p	PAR-CLIP	20371350
MIRT569644	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT569643	hsa-miR-30a-3p	PAR-CLIP	20371350
MIRT569642	hsa-miR-30d-3p	PAR-CLIP	20371350
MIRT569641	hsa-miR-30e-3p	PAR-CLIP	20371350
MIRT569651	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT569650	hsa-miR-641	PAR-CLIP	20371350
MIRT569649	hsa-miR-1324	PAR-CLIP	20371350
MIRT569648	hsa-miR-8060	PAR-CLIP	20371350
MIRT569647	hsa-miR-1250-3p	PAR-CLIP	20371350
MIRT569646	hsa-miR-549a	PAR-CLIP	20371350
MIRT569645	hsa-miR-7154-5p	PAR-CLIP	20371350
MIRT569644	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT569643	hsa-miR-30a-3p	PAR-CLIP	20371350
MIRT569642	hsa-miR-30d-3p	PAR-CLIP	20371350
MIRT569641	hsa-miR-30e-3p	PAR-CLIP	20371350
MIRT541948	hsa-miR-8485	PAR-CLIP	21572407
MIRT541947	hsa-miR-603	PAR-CLIP	21572407
MIRT541946	hsa-miR-4798-3p	PAR-CLIP	21572407
MIRT541945	hsa-miR-216b-3p	PAR-CLIP	21572407
MIRT541944	hsa-miR-342-3p	PAR-CLIP	21572407
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	27418678
MIRT541944	hsa-miR-342-3p	HITS-CLIP	27418678
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	27418678
MIRT541947	hsa-miR-603	HITS-CLIP	27418678
MIRT541948	hsa-miR-8485	HITS-CLIP	27418678
MIRT541948	hsa-miR-8485	HITS-CLIP	21572407
MIRT707288	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT707287	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT541947	hsa-miR-603	HITS-CLIP	21572407
MIRT707286	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT707285	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707284	hsa-miR-3941	HITS-CLIP	21572407
MIRT707283	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT707282	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707281	hsa-miR-6516-3p	HITS-CLIP	21572407
MIRT707280	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT541948	hsa-miR-8485	HITS-CLIP	23824327
MIRT541947	hsa-miR-603	HITS-CLIP	23824327
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	23824327
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT541944	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT541948	hsa-miR-8485	HITS-CLIP	23824327
MIRT541947	hsa-miR-603	HITS-CLIP	23824327
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	23824327
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT541944	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT541948	hsa-miR-8485	HITS-CLIP	23824327
MIRT541947	hsa-miR-603	HITS-CLIP	23824327
MIRT541946	hsa-miR-4798-3p	HITS-CLIP	23824327
MIRT541945	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT541944	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT569651	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT569650	hsa-miR-641	PAR-CLIP	20371350
MIRT569649	hsa-miR-1324	PAR-CLIP	20371350
MIRT569648	hsa-miR-8060	PAR-CLIP	20371350
MIRT569647	hsa-miR-1250-3p	PAR-CLIP	20371350
MIRT569646	hsa-miR-549a	PAR-CLIP	20371350
MIRT569645	hsa-miR-7154-5p	PAR-CLIP	20371350
MIRT569644	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT569643	hsa-miR-30a-3p	PAR-CLIP	20371350
MIRT569642	hsa-miR-30d-3p	PAR-CLIP	20371350
MIRT569641	hsa-miR-30e-3p	PAR-CLIP	20371350
MIRT569651	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT569650	hsa-miR-641	PAR-CLIP	20371350
MIRT569649	hsa-miR-1324	PAR-CLIP	20371350
MIRT569648	hsa-miR-8060	PAR-CLIP	20371350
MIRT569647	hsa-miR-1250-3p	PAR-CLIP	20371350
MIRT569646	hsa-miR-549a	PAR-CLIP	20371350
MIRT569645	hsa-miR-7154-5p	PAR-CLIP	20371350
MIRT569644	hsa-miR-3942-3p	PAR-CLIP	20371350
MIRT569643	hsa-miR-30a-3p	PAR-CLIP	20371350
MIRT569642	hsa-miR-30d-3p	PAR-CLIP	20371350
MIRT569641	hsa-miR-30e-3p	PAR-CLIP	20371350
MIRT541948	hsa-miR-8485	PAR-CLIP	21572407
MIRT541947	hsa-miR-603	PAR-CLIP	21572407
MIRT541946	hsa-miR-4798-3p	PAR-CLIP	21572407
MIRT541945	hsa-miR-216b-3p	PAR-CLIP	21572407
MIRT541944	hsa-miR-342-3p	PAR-CLIP	21572407

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005737	Component	Cytoplasm	IEA

MIM	HGNC	e!Ensembl
614000	31992	ENSG00000271425

Protein

UniProt ID

Q6P3W6

Protein name

NBPF family member NBPF10 (Neuroblastoma breakpoint family member 10)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06758	Olduvai	178 → 240	Olduvai domain	Domain
PF06758	Olduvai	450 → 511	Olduvai domain	Domain
PF06758	Olduvai	535 → 597	Olduvai domain	Domain
PF06758	Olduvai	607 → 672	Olduvai domain	Domain
PF06758	Olduvai	682 → 747	Olduvai domain	Domain
PF06758	Olduvai	757 → 822	Olduvai domain	Domain

Sequence

MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY
EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE
KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA
EKKQQFRNLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
EGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAI
TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK
GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF
YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG
YLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPE
VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
S

Sequence length

841

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	29059683

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Acute Coronary Syndrome	Stimulate	30242056
Breast Neoplasms	Associate	37454130
Neoplasms	Associate	37454130

NBPF10 (NBPF member 10)