ZNF831 (zinc finger protein 831)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 128611
• Gene name: Zinc finger protein 831
• Gene symbol: ZNF831
• Synonyms (NCBI Gene): C20orf174
• Chromosome: 20
• Chromosome location: 20q13.32

miRNA Show/Hide all (154)

miRTarBase ID	miRNA	Experiments	Reference
MIRT650983	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT650982	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT650981	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT650980	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT650979	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT650978	hsa-miR-5193	HITS-CLIP	23824327
MIRT650977	hsa-miR-4470	HITS-CLIP	23824327
MIRT650976	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT650975	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT650974	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT650983	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT650982	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT650981	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT650980	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT650979	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT650978	hsa-miR-5193	HITS-CLIP	23824327
MIRT650977	hsa-miR-4470	HITS-CLIP	23824327
MIRT650976	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT650975	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT650974	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT1541577	hsa-miR-1206	CLIP-seq
MIRT1541578	hsa-miR-1252	CLIP-seq
MIRT1541579	hsa-miR-127-5p	CLIP-seq
MIRT1541580	hsa-miR-141	CLIP-seq
MIRT1541581	hsa-miR-1825	CLIP-seq
MIRT1541582	hsa-miR-185	CLIP-seq
MIRT1541583	hsa-miR-200a	CLIP-seq
MIRT1541584	hsa-miR-2110	CLIP-seq
MIRT1541585	hsa-miR-219-5p	CLIP-seq
MIRT1541586	hsa-miR-2277-3p	CLIP-seq
MIRT1541587	hsa-miR-3120-3p	CLIP-seq
MIRT1541588	hsa-miR-3145-3p	CLIP-seq
MIRT1541589	hsa-miR-3163	CLIP-seq
MIRT1541590	hsa-miR-340	CLIP-seq
MIRT1541591	hsa-miR-3611	CLIP-seq
MIRT1541592	hsa-miR-3617	CLIP-seq
MIRT1541593	hsa-miR-3662	CLIP-seq
MIRT1541594	hsa-miR-3929	CLIP-seq
MIRT1541595	hsa-miR-3973	CLIP-seq
MIRT1541596	hsa-miR-4271	CLIP-seq
MIRT1541597	hsa-miR-4306	CLIP-seq
MIRT1541598	hsa-miR-4317	CLIP-seq
MIRT1541599	hsa-miR-4419b	CLIP-seq
MIRT1541600	hsa-miR-4445	CLIP-seq
MIRT1541601	hsa-miR-4478	CLIP-seq
MIRT1541602	hsa-miR-4635	CLIP-seq
MIRT1541603	hsa-miR-4644	CLIP-seq
MIRT1541604	hsa-miR-4718	CLIP-seq
MIRT1541605	hsa-miR-4725-3p	CLIP-seq
MIRT1541606	hsa-miR-4761-5p	CLIP-seq
MIRT1541607	hsa-miR-4775	CLIP-seq
MIRT1541608	hsa-miR-4782-3p	CLIP-seq
MIRT1541609	hsa-miR-4797-5p	CLIP-seq
MIRT1541610	hsa-miR-485-5p	CLIP-seq
MIRT1541611	hsa-miR-490-3p	CLIP-seq
MIRT1541612	hsa-miR-508-3p	CLIP-seq
MIRT1541613	hsa-miR-514	CLIP-seq
MIRT1541614	hsa-miR-514b-3p	CLIP-seq
MIRT1541615	hsa-miR-515-3p	CLIP-seq
MIRT1541616	hsa-miR-519e	CLIP-seq
MIRT1541617	hsa-miR-545	CLIP-seq
MIRT1541618	hsa-miR-548a-5p	CLIP-seq
MIRT1541619	hsa-miR-548ab	CLIP-seq
MIRT1541620	hsa-miR-548ak	CLIP-seq
MIRT1541621	hsa-miR-548b-5p	CLIP-seq
MIRT1541622	hsa-miR-548c-5p	CLIP-seq
MIRT1541623	hsa-miR-548d-5p	CLIP-seq
MIRT1541624	hsa-miR-548h	CLIP-seq
MIRT1541625	hsa-miR-548i	CLIP-seq
MIRT1541626	hsa-miR-548j	CLIP-seq
MIRT1541627	hsa-miR-548w	CLIP-seq
MIRT1541628	hsa-miR-548y	CLIP-seq
MIRT1541629	hsa-miR-552	CLIP-seq
MIRT1541630	hsa-miR-559	CLIP-seq
MIRT1541631	hsa-miR-641	CLIP-seq
MIRT1541632	hsa-miR-668	CLIP-seq
MIRT1541633	hsa-miR-802	CLIP-seq
MIRT2163418	hsa-miR-103a	CLIP-seq
MIRT2163419	hsa-miR-107	CLIP-seq
MIRT1541579	hsa-miR-127-5p	CLIP-seq
MIRT2163420	hsa-miR-1470	CLIP-seq
MIRT1541581	hsa-miR-1825	CLIP-seq
MIRT2163421	hsa-miR-203	CLIP-seq
MIRT2163422	hsa-miR-2861	CLIP-seq
MIRT2163423	hsa-miR-3616-5p	CLIP-seq
MIRT2163424	hsa-miR-362-5p	CLIP-seq
MIRT2163425	hsa-miR-3647-5p	CLIP-seq
MIRT2163426	hsa-miR-3652	CLIP-seq
MIRT2163427	hsa-miR-4282	CLIP-seq
MIRT2163428	hsa-miR-4430	CLIP-seq
MIRT2163429	hsa-miR-4505	CLIP-seq
MIRT2163430	hsa-miR-4747-5p	CLIP-seq
MIRT2163431	hsa-miR-500a	CLIP-seq
MIRT2163432	hsa-miR-500b	CLIP-seq
MIRT2163433	hsa-miR-548c-3p	CLIP-seq
MIRT2163434	hsa-miR-573	CLIP-seq
MIRT2163435	hsa-miR-578	CLIP-seq
MIRT2163436	hsa-miR-590-3p	CLIP-seq
MIRT2163437	hsa-miR-642a	CLIP-seq
MIRT2163438	hsa-miR-647	CLIP-seq
MIRT2163439	hsa-miR-718	CLIP-seq
MIRT2382654	hsa-miR-1265	CLIP-seq
MIRT2382655	hsa-miR-1272	CLIP-seq
MIRT2382656	hsa-miR-145	CLIP-seq
MIRT1541581	hsa-miR-1825	CLIP-seq
MIRT2382657	hsa-miR-199a-5p	CLIP-seq
MIRT2382658	hsa-miR-199b-5p	CLIP-seq
MIRT2382659	hsa-miR-200b	CLIP-seq
MIRT2382660	hsa-miR-200c	CLIP-seq
MIRT2382661	hsa-miR-2392	CLIP-seq
MIRT2382662	hsa-miR-24	CLIP-seq
MIRT2382663	hsa-miR-27a	CLIP-seq
MIRT2382664	hsa-miR-27b	CLIP-seq
MIRT2382665	hsa-miR-3065-5p	CLIP-seq
MIRT1541587	hsa-miR-3120-3p	CLIP-seq
MIRT2382666	hsa-miR-3140-3p	CLIP-seq
MIRT2382667	hsa-miR-3148	CLIP-seq
MIRT2382668	hsa-miR-3155	CLIP-seq
MIRT2382669	hsa-miR-3155b	CLIP-seq
MIRT2382670	hsa-miR-337-3p	CLIP-seq
MIRT2382671	hsa-miR-3646	CLIP-seq
MIRT2382672	hsa-miR-369-3p	CLIP-seq
MIRT2382673	hsa-miR-3942-5p	CLIP-seq
MIRT2382674	hsa-miR-412	CLIP-seq
MIRT2382675	hsa-miR-429	CLIP-seq
MIRT2382676	hsa-miR-4645-3p	CLIP-seq
MIRT2382677	hsa-miR-4667-5p	CLIP-seq
MIRT2382678	hsa-miR-4698	CLIP-seq
MIRT2382679	hsa-miR-4700-5p	CLIP-seq
MIRT2382680	hsa-miR-4703-5p	CLIP-seq
MIRT2382681	hsa-miR-4708-3p	CLIP-seq
MIRT2382682	hsa-miR-4724-3p	CLIP-seq
MIRT2382683	hsa-miR-4786-3p	CLIP-seq
MIRT2382684	hsa-miR-484	CLIP-seq
MIRT2382685	hsa-miR-495	CLIP-seq
MIRT2382686	hsa-miR-513a-5p	CLIP-seq
MIRT2163433	hsa-miR-548c-3p	CLIP-seq
MIRT2382687	hsa-miR-651	CLIP-seq
MIRT1541633	hsa-miR-802	CLIP-seq
MIRT2382654	hsa-miR-1265	CLIP-seq
MIRT2397761	hsa-miR-1912	CLIP-seq
MIRT2382661	hsa-miR-2392	CLIP-seq
MIRT2382666	hsa-miR-3140-3p	CLIP-seq
MIRT2382682	hsa-miR-4724-3p	CLIP-seq
MIRT2163433	hsa-miR-548c-3p	CLIP-seq
MIRT2382687	hsa-miR-651	CLIP-seq
MIRT2673353	hsa-miR-1303	CLIP-seq
MIRT2673354	hsa-miR-4270	CLIP-seq
MIRT2673355	hsa-miR-4441	CLIP-seq
MIRT2673356	hsa-miR-4653-3p	CLIP-seq
MIRT2673353	hsa-miR-1303	CLIP-seq
MIRT2673354	hsa-miR-4270	CLIP-seq
MIRT2673355	hsa-miR-4441	CLIP-seq
MIRT2673356	hsa-miR-4653-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5JPB2
• Protein name: Zinc finger protein 831
• PDB: 8FUF
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	172 → 196	Zinc finger, C2H2 type	Domain

• Sequence:

  MEVPEPTCPAPPARDQPAPTPGPPGAPGGQASPHLTLGPVLLPPEQGLAPPTVFLKALPI
  PLYHTVPPGGLQPRAPLVTGSLDGGNVPFILSPVLQPEGPGPTQVGKPAAPTLTVNIVGT
  LPVLSPGLGPTLGSPGKVRNAGKYLCPHCGRDCLKPSVLEKHIRSHTGERPFPCATCGIA
  FKTQSNLYKHRRTQTHLNNSRLSSESEGAGGGLLEEGDKAGEPPRPEGRGESRCQGMHEG
  ASERPLSPGAHVPLLAKNLDVRTEAAPCPGSAFADREAPWDSAPMASPGLPAASTQPWRK
  LPEQKSPTAGKPCALQRQQATAAEKPWDAKAPEGRLRKCESTDSGYLSRSDSAEQPHAPC
  SPLHSLSEHSAESEGEGGPGPGPGVAGAEPGAREAGLELEKKRLEERIAQLISHNQAVVD
  DAQLDNVRPRKTGLSKQGSIDLPTPYTYKDSFHFDIRALEPGRRRAPGPVRSTWTPPDKS
  RPLFFHSVPTQLSTTVECVPVTRSNSLPFVEGSRTWLEPREPRDPWSRTQKPLSPRPGPA
  RLGCRSGLSSTDVPSGHPRALVRQAAVEDLPGTPIGDALVPAEDTDAKRTAAREAMAGKG
  RAGGRKCGQRRLKMFSQEKWQVYGDETFKRIYQKMKASPHGGKKAREVGMGSGAELGFPL
  QKEAAGSSGTVPTQDRRTPVHEDISAGATPEPWGNPPALEASLVTEPTKHGETVARRGDS
  DRPRVEEAVSSPALGGRDSPCSGSRSPLVSPNGRLELGWQMPPAPGPLKGGDVEAPRPVW
  PDPKLEGGARGVGDVQETCLWAQTVLRWPSRGSGEDKLPSERKKLKVEDLHSWKQPEPVS
  AETPGGPTQPASLSSQKQDADPGEVPGGSKESARQVGEPLESSGASLAAASVALKRVGPR
  DKATPLHPAAPAPAEHPSLATPPQAPRVLSALADNAFSPKYLLRLPQAETPLPLPIPWGP
  RHSQDSLCSSGWPEERASFVGSGLGTPLSPSPASGPSPGEADSILEDPSCSRPQDGRKGA
  QLGGDKGDRMATSRPAARELPISAPGAPREATSSPPTPTCEAHLVQDMEGDSHRIHRLCM
  GSTLARARLSGDVLNPWVPNWELGEPPGNAPEDPSSGPLVGPDPCSPLQPGSFLTALTRP
  QGVPPGWPELALSSHSGTSRSHSTRSPHSTQNPFPSLKAEPRLTWCCLSRSVPLPAEQKA
  KAASVYLAVHFPGSSLRDEGPNGPPGSNGGWTWTSPGEGGPAQMSKFSYPTVPGVMPQHQ
  VSEPEWKKGLPWRAKMSRGNSKQRKLKINPKRYKGNFLQSCVQLRASRLRTPTWVRRRSR
  HPPALEGLKPCRTPGQTSSEIAGLNLQEEPSCATSESPPCCGKEEKKEGDCRQTLGTLSL
  GTSSRIVREMDKRTVKDISPSAGEHGDCTTHSTAATSGLSLQSDTCLAVVNDVPLPPGKG
  LDLGLLETQLLASQDSVSTDPKPYIFSDAQRPSSFGSKGTFPHHDIATSVAAVCISLPVR
  TDHIAQEIHSAESRDHSQTAGRTLTSSSPDSKVTEEGRAQTLLPGRPSSGQRISDSVPLE
  STEKTHLEIPASGPSSASSHHKEGRHKTFFPSRGQYGCGEMTVPCPSLGSDGRKRQVSGL
  ITRKDSVVPSKPEQPIEIPEAPSKSLKKRSLEGMRKQTRVEFSDTSSDDEDRLVIEI

• Sequence length: 1677

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (18)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ANKYLOSING SPONDYLITIS	—	GWAS catalog	26974007	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTROCYTOMA	—	GWAS catalog	36810956	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	40645996	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	30595370	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	29212778, 33020668, 36474045, 41022758	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CROHN'S DISEASE	—	GWAS catalog	23128233, 26192919, 26974007, 28067908, 37156999	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESSENTIAL HYPERTENSION	—	GWAS catalog	39024449	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	19430479, 21909115, 31879980, 38965376, 39024449, 39789286	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION, PREGNANCY-INDUCED	—	GWAS catalog	36553520, 37285119	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	23128233, 26192919, 28067908, 37156999	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	34734193	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	CTD	21499247	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	33532862, 38072966	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PREECLAMPSIA	—	GWAS catalog	33239696, 37248299, 37285119, 40069456	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	26974007	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCLEROSING CHOLANGITIS	—	GWAS catalog	26974007	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SYSTEMIC LUPUS ERYTHEMATOSUS	—	GWAS catalog	36750564	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	23128233, 26192919, 26974007, 28067908, 37156999	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (15)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Ankylosing spondylitis	Ankylosing Spondylitis	GWASCAT_DG	26974007		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only
Cholangitis, Sclerosing	Cholangitis	GWASCAT_DG	26974007		★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	GWASCAT_DG	29212778		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Coronary heart disease	Coronary Heart Disease	GWASDB_DG	21347282		★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	GWASCAT_DG	26192919, 26974007, 28067908		★☆☆☆☆ Found in Text Mining only
Diabetes Gestational	Gestational diabetes	Pubtator	39456889	Associate	★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	39456889	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	GWASDB_DG	19430479, 21909115		★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	GWASCAT_DG	19430479, 21909115		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	GWASCAT_DG	23128233, 26192919, 28067908		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	GWASDB_DG	23128233		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	CTD_human_DG	21499247		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Psoriasis	Psoriasis	GWASCAT_DG	26974007		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ulcerative Colitis	Ulcerative colitis	GWASCAT_DG	26974007		★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

Sort by: Blended Diseases Pathways Evidence source

AQP12B 1 shared diseaseSclerosing cholangitis 2 shared evidence sourcesGWAS catalog (Ankylosing spondylitis), GWAS catalog (Sclerosing cholangitis) Related via 1 shared disease including Sclerosing cholangitis — evidence mostly GWAS catalog. GAL3ST2 1 shared diseaseSclerosing cholangitis 2 shared evidence sourcesGWAS catalog (Ankylosing spondylitis), GWAS catalog (Sclerosing cholangitis) Related via 1 shared disease including Sclerosing cholangitis — evidence mostly GWAS catalog. GLYAT 1 shared diseaseSclerosing cholangitis 2 shared evidence sourcesGWAS catalog (Ankylosing spondylitis), GWAS catalog (Sclerosing cholangitis) Related via 1 shared disease including Sclerosing cholangitis — evidence mostly GWAS catalog. KSR1 1 shared diseaseSclerosing cholangitis 2 shared evidence sourcesGWAS catalog (Ankylosing spondylitis), GWAS catalog (Sclerosing cholangitis) Related via 1 shared disease including Sclerosing cholangitis — evidence mostly GWAS catalog. LPXN 1 shared diseaseSclerosing cholangitis 2 shared evidence sourcesGWAS catalog (Ankylosing spondylitis), GWAS catalog (Sclerosing cholangitis) Related via 1 shared disease including Sclerosing cholangitis — evidence mostly GWAS catalog.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
AQP12B	1	["Sclerosing cholangitis"]	0	[]	2	["GWAS catalog (Ankylosing spondylitis)","GWAS catalog (Sclerosing cholangitis)"]
GAL3ST2	1	["Sclerosing cholangitis"]	0	[]	2	["GWAS catalog (Ankylosing spondylitis)","GWAS catalog (Sclerosing cholangitis)"]
GLYAT	1	["Sclerosing cholangitis"]	0	[]	2	["GWAS catalog (Ankylosing spondylitis)","GWAS catalog (Sclerosing cholangitis)"]
KSR1	1	["Sclerosing cholangitis"]	0	[]	2	["GWAS catalog (Ankylosing spondylitis)","GWAS catalog (Sclerosing cholangitis)"]
LPXN	1	["Sclerosing cholangitis"]	0	[]	2	["GWAS catalog (Ankylosing spondylitis)","GWAS catalog (Sclerosing cholangitis)"]

Diseases Linked via Similar Genes

Open angle glaucoma Linked via 2 of 5 related genesGLYAT, LPXN Asthma Linked via 1 of 5 related genesGAL3ST2 Bipolar disorder Linked via 1 of 5 related genesGLYAT Rheumatoid arthritis Linked via 1 of 5 related genesKSR1 Alzheimer disease Linked via 1 of 5 related genesLPXN

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Open angle glaucoma	2	["GLYAT","LPXN"]
Asthma	1	["GAL3ST2"]
Bipolar disorder	1	["GLYAT"]
Rheumatoid arthritis	1	["KSR1"]
Alzheimer disease	1	["LPXN"]