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Gene Gene information from NCBI Gene database.
Entrez ID 54554
Gene name WD repeat domain 5B
Gene symbol WDR5B
Synonyms (NCBI Gene)
-
Chromosome 3
Chromosome location 3q21.1
Summary This intronless gene encodes a protein containing several WD40 repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, including a trp-asp at the C-terminal end. The encoded protein may mediate protein-pro
miRNA miRNA information provided by mirtarbase database.
435 Show/Hide all (435)
miRTarBase ID miRNA Experiments Reference
MIRT051163 hsa-miR-16-5p CLASH 23622248
MIRT647369 hsa-miR-125a-3p HITS-CLIP 23824327
MIRT647368 hsa-miR-764 HITS-CLIP 23824327
MIRT647367 hsa-miR-3934-5p HITS-CLIP 23824327
MIRT672095 hsa-miR-371b-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
GO ID Ontology Definition Evidence Reference
GO:0042393 Function Histone binding IBA
GO:0048188 Component Set1C/COMPASS complex IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
621240 17826 ENSG00000196981
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86VZ2
Protein name WD repeat-containing protein 5B
Protein function May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00400 WD40 115 → 153 WD domain, G-beta repeat Repeat
PF00400 WD40 157 → 195 WD domain, G-beta repeat Repeat
PF00400 WD40 73 → 111 WD domain, G-beta repeat Repeat
PF00400 WD40 32 → 68 WD domain, G-beta repeat Repeat
PF00400 WD40 287 → 327 WD domain, G-beta repeat Repeat
Sequence
MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSS
ADRLIIIW
GAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKT
LKGHSNYVFCCNFNPPSNLIISGSFDETVKIWE
VKTGKCLKTLSAHSDPVSAVHFNCSGS
LIVSGSYDGLCRIWD
AASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYS
RGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV
ISAACHPTENLIASAALENDKTIKLWM
SNH
Sequence length 330
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Polycomb repressive complex
Cushing syndrome