TRIP10 (thyroid hormone receptor interactor 10)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 9322
• Gene name: Thyroid hormone receptor interactor 10
• Gene symbol: TRIP10
• Synonyms (NCBI Gene): CIP4, HSTP, STOT, STP, TRIP-10
• Chromosome: 19
• Chromosome location: 19p13.3

miRNA Show/Hide all (213)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016147	hsa-miR-615-3p	Sequencing	20371350
MIRT020146	hsa-miR-130b-3p	Sequencing	20371350
MIRT021113	hsa-miR-186-5p	Sequencing	20371350
MIRT028160	hsa-miR-93-5p	Sequencing	20371350
MIRT437665	hsa-miR-195-5p	Microarray, qRT-PCR	22815788
MIRT028160	hsa-miR-93-5p	Microarray, qRT-PCR	22815788
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT647926	hsa-miR-3163	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT647925	hsa-miR-568	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT641185	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT465240	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT028160	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT465238	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT465237	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT465236	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT465235	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT465234	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT465233	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT465232	hsa-miR-5590-3p	PAR-CLIP	23592263
MIRT465231	hsa-miR-142-5p	PAR-CLIP	23592263
MIRT465230	hsa-miR-3609	PAR-CLIP	23592263
MIRT465229	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT465228	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT465227	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT465226	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT465225	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT465224	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT465223	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT465222	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT465220	hsa-miR-4489	PAR-CLIP	23592263
MIRT465219	hsa-miR-4283	PAR-CLIP	23592263
MIRT465218	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT465217	hsa-miR-6801-5p	PAR-CLIP	23592263
MIRT465216	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT465215	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT465214	hsa-miR-153-3p	PAR-CLIP	23592263
MIRT465240	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT028160	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT465238	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT465237	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT465236	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT465235	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT465234	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT465233	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT465232	hsa-miR-5590-3p	PAR-CLIP	23592263
MIRT465231	hsa-miR-142-5p	PAR-CLIP	23592263
MIRT465230	hsa-miR-3609	PAR-CLIP	23592263
MIRT465229	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT465228	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT465227	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT465226	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT465225	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT465224	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT465223	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT465222	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT465221	hsa-miR-4786-3p	PAR-CLIP	23592263
MIRT465220	hsa-miR-4489	PAR-CLIP	23592263
MIRT465219	hsa-miR-4283	PAR-CLIP	23592263
MIRT465218	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT465217	hsa-miR-6801-5p	PAR-CLIP	23592263
MIRT465216	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT465215	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT465214	hsa-miR-153-3p	PAR-CLIP	23592263
MIRT620374	hsa-miR-3149	HITS-CLIP	27418678
MIRT647926	hsa-miR-3163	HITS-CLIP	27418678
MIRT647925	hsa-miR-568	HITS-CLIP	27418678
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT647926	hsa-miR-3163	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT647925	hsa-miR-568	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT641185	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT637612	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT620374	hsa-miR-3149	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT611386	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT611385	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT465240	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT028160	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT465238	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT465237	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT465236	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT465235	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT465234	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT465233	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT465232	hsa-miR-5590-3p	PAR-CLIP	23592263
MIRT465231	hsa-miR-142-5p	PAR-CLIP	23592263
MIRT465230	hsa-miR-3609	PAR-CLIP	23592263
MIRT465229	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT465228	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT465227	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT465226	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT465225	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT465224	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT465223	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT465222	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT465220	hsa-miR-4489	PAR-CLIP	23592263
MIRT465219	hsa-miR-4283	PAR-CLIP	23592263
MIRT465218	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT465217	hsa-miR-6801-5p	PAR-CLIP	23592263
MIRT465216	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT465215	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT465214	hsa-miR-153-3p	PAR-CLIP	23592263
MIRT465240	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT028160	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT465238	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT465237	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT465236	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT465235	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT465234	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT465233	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT465232	hsa-miR-5590-3p	PAR-CLIP	23592263
MIRT465231	hsa-miR-142-5p	PAR-CLIP	23592263
MIRT465230	hsa-miR-3609	PAR-CLIP	23592263
MIRT465229	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT465228	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT465227	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT465226	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT465225	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT465224	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT465223	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT465222	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT465221	hsa-miR-4786-3p	PAR-CLIP	23592263
MIRT465220	hsa-miR-4489	PAR-CLIP	23592263
MIRT465219	hsa-miR-4283	PAR-CLIP	23592263
MIRT465218	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT465217	hsa-miR-6801-5p	PAR-CLIP	23592263
MIRT465216	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT465215	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT465214	hsa-miR-153-3p	PAR-CLIP	23592263
MIRT1456391	hsa-miR-1275	CLIP-seq
MIRT1456392	hsa-miR-214	CLIP-seq
MIRT1456393	hsa-miR-3619-5p	CLIP-seq
MIRT1456394	hsa-miR-3940-5p	CLIP-seq
MIRT1456395	hsa-miR-4507	CLIP-seq
MIRT1456396	hsa-miR-4651	CLIP-seq
MIRT1456397	hsa-miR-4665-5p	CLIP-seq
MIRT1456398	hsa-miR-486-3p	CLIP-seq
MIRT1456399	hsa-miR-608	CLIP-seq
MIRT1456400	hsa-miR-657	CLIP-seq
MIRT1456401	hsa-miR-761	CLIP-seq
MIRT1456391	hsa-miR-1275	CLIP-seq
MIRT1456392	hsa-miR-214	CLIP-seq
MIRT2136798	hsa-miR-3117-3p	CLIP-seq
MIRT2136799	hsa-miR-3169	CLIP-seq
MIRT1456393	hsa-miR-3619-5p	CLIP-seq
MIRT1456394	hsa-miR-3940-5p	CLIP-seq
MIRT2136800	hsa-miR-3941	CLIP-seq
MIRT1456395	hsa-miR-4507	CLIP-seq
MIRT2136801	hsa-miR-4515	CLIP-seq
MIRT1456396	hsa-miR-4651	CLIP-seq
MIRT2136802	hsa-miR-466	CLIP-seq
MIRT1456397	hsa-miR-4665-5p	CLIP-seq
MIRT2136803	hsa-miR-4672	CLIP-seq
MIRT2136804	hsa-miR-4759	CLIP-seq
MIRT1456398	hsa-miR-486-3p	CLIP-seq
MIRT2136805	hsa-miR-496	CLIP-seq
MIRT2136806	hsa-miR-499-3p	CLIP-seq
MIRT2136807	hsa-miR-499a-3p	CLIP-seq
MIRT1456399	hsa-miR-608	CLIP-seq
MIRT1456400	hsa-miR-657	CLIP-seq
MIRT1456401	hsa-miR-761	CLIP-seq

Gene ontology (GO) Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001891	Component	Phagocytic cup	IEA
GO:0005515	Function	Protein binding	IPI	16318909, 16630611, 21044950, 25416956, 25825872, 26751515, 32296183, 32814053
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	9210375
GO:0005764	Component	Lysosome	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005938	Component	Cell cortex	IEA
GO:0006897	Process	Endocytosis	IEA
GO:0007154	Process	Cell communication	NAS	9210375
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	9210375
GO:0008289	Function	Lipid binding	IEA
GO:0016020	Component	Membrane	IEA
GO:0030036	Process	Actin cytoskeleton organization	NAS	9210375
GO:0042802	Function	Identical protein binding	IPI	17512409, 18329367, 25416956, 32296183
GO:0042995	Component	Cell projection	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: 604504
• HGNC: 12304
• e!Ensembl: ENSG00000125733

Protein

• UniProt ID: Q15642
• Protein name: Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10)
• Protein function: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as pho
• PDB: 2CT4 , 2EFK , 2KE4
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00018	SH3_1	546 → 593	SH3 domain	Domain
  PF00611	FCH	10 → 89	Fes/CIP4, and EFC/F-BAR homology domain	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea. {ECO:0000269|PubMed:11294612
• Sequence:

  MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAK
  DDPESKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEG
  RRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRS
  HMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELE
  VVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDFSQPMNRAPSDSSL
  GTPSDGRPELRGPGRSRTKRWPFGKKNKPRPPPLSPLGGPVPSALPNGPPSPRSGRDPLA
  ILSEISKSVKPRLASFRSLRGSRGTVVTEDFSHLPPEQQRKRLQQQLEERSRELQKEVDQ
  REALKKMKDVYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVLSNRG
  DSLSRHARPPDPPASAPPDSSSNSASQDTKESSEEPPSEESQDTPIYTEFDEDFEEEPTS
  PIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYLRVTL
  N

• Sequence length: 601

Pathways

KEGG Pathway	Reactome Pathway
Insulin signaling pathway	Rho GTPase cycle
	Clathrin-mediated endocytosis

Related Genes

Sort by: Blended Diseases Pathways Evidence source

RHOQ 2 shared pathwaysInsulin signaling pathway, Rho GTPase cycle Related via 2 shared pathways including Insulin signaling pathway, Rho GTPase cycle. ITSN1 2 shared pathwaysRho GTPase cycle, Clathrin-mediated endocytosis Related via 2 shared pathways including Rho GTPase cycle, Clathrin-mediated endocytosis. OCRL 2 shared pathwaysRho GTPase cycle, Clathrin-mediated endocytosis Related via 2 shared pathways including Rho GTPase cycle, Clathrin-mediated endocytosis. CBL 2 shared pathwaysInsulin signaling pathway, Clathrin-mediated endocytosis Related via 2 shared pathways including Insulin signaling pathway, Clathrin-mediated endocytosis. SOS2 2 shared pathwaysInsulin signaling pathway, Rho GTPase cycle Related via 2 shared pathways including Insulin signaling pathway, Rho GTPase cycle.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
RHOQ	0	[]	2	["Insulin signaling pathway","Rho GTPase cycle"]	0	[]
ITSN1	0	[]	2	["Rho GTPase cycle","Clathrin-mediated endocytosis"]	0	[]
OCRL	0	[]	2	["Rho GTPase cycle","Clathrin-mediated endocytosis"]	0	[]
CBL	0	[]	2	["Insulin signaling pathway","Clathrin-mediated endocytosis"]	0	[]
SOS2	0	[]	2	["Insulin signaling pathway","Rho GTPase cycle"]	0	[]

Diseases Linked via Similar Genes

Intellectual developmental disorder Linked via 2 of 5 related genesITSN1, OCRL Neurodevelopmental disorder Linked via 2 of 5 related genesITSN1, CBL Desbuquois syndrome Linked via 2 of 5 related genesCBL, SOS2 Noonan syndrome Linked via 2 of 5 related genesCBL, SOS2 Autism Linked via 1 of 5 related genesITSN1

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Intellectual developmental disorder	2	["ITSN1","OCRL"]
Neurodevelopmental disorder	2	["ITSN1","CBL"]
Desbuquois syndrome	2	["CBL","SOS2"]
Noonan syndrome	2	["CBL","SOS2"]
Autism	1	["ITSN1"]