TJP1 (tight junction protein 1)

Gene

• Entrez ID: 7082
• Gene name: Tight junction protein 1
• Gene symbol: TJP1
• Synonyms (NCBI Gene): ZO-1
• Chromosome: 15
• Chromosome location: 15q13.1
• Summary: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules betwee

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004341	hsa-miR-212-3p	Western blot	18162065
MIRT004341	hsa-miR-212-3p	Luciferase reporter assay	18162065
MIRT020884	hsa-miR-155-5p	Proteomics	18668040
MIRT051942	hsa-let-7b-5p	CLASH	23622248
MIRT050793	hsa-miR-17-5p	CLASH	23622248
MIRT042969	hsa-miR-324-3p	CLASH	23622248
MIRT039699	hsa-miR-615-3p	CLASH	23622248
MIRT438931	hsa-miR-105-5p	In situ hybridization, qRT-PCR, Luciferase reporter assay, Western blot, Microarray	24735924
MIRT0004379	hsa-miR-105-5p	In situ hybridization, qRT-PCR, Luciferase reporter assay, Western blot, Microarray	24735924
MIRT698475	hsa-miR-548ac	HITS-CLIP	23313552
MIRT698474	hsa-miR-548bb-3p	HITS-CLIP	23313552
MIRT698473	hsa-miR-548d-3p	HITS-CLIP	23313552
MIRT698472	hsa-miR-548h-3p	HITS-CLIP	23313552
MIRT698471	hsa-miR-548z	HITS-CLIP	23313552
MIRT698470	hsa-miR-548ae-3p	HITS-CLIP	23313552
MIRT698469	hsa-miR-548ah-3p	HITS-CLIP	23313552
MIRT698468	hsa-miR-548aj-3p	HITS-CLIP	23313552
MIRT698467	hsa-miR-548am-3p	HITS-CLIP	23313552
MIRT698466	hsa-miR-548aq-3p	HITS-CLIP	23313552
MIRT698465	hsa-miR-548j-3p	HITS-CLIP	23313552
MIRT698464	hsa-miR-548x-3p	HITS-CLIP	23313552
MIRT698463	hsa-miR-5582-3p	HITS-CLIP	23313552
MIRT698461	hsa-miR-5700	HITS-CLIP	23313552
MIRT698462	hsa-miR-4731-3p	HITS-CLIP	23313552
MIRT698460	hsa-miR-4801	HITS-CLIP	23313552
MIRT698459	hsa-miR-802	HITS-CLIP	23313552
MIRT553632	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT553631	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT553630	hsa-miR-107	PAR-CLIP	21572407
MIRT553629	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553628	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT553627	hsa-miR-383-3p	PAR-CLIP	21572407
MIRT553626	hsa-miR-194-5p	PAR-CLIP	21572407
MIRT553625	hsa-miR-4799-5p	PAR-CLIP	21572407
MIRT732222	hsa-miR-212-5p	Luciferase reporter assay, Western blot	26692142
MIRT732222	hsa-miR-212-5p	Luciferase reporter assay, Western blot	26692142
MIRT735353	hsa-miR-4720-3p	Luciferase reporter assay, Western blotting, In situ hybridization	32314520
MIRT698475	hsa-miR-548ac	HITS-CLIP	23313552
MIRT698474	hsa-miR-548bb-3p	HITS-CLIP	23313552
MIRT698473	hsa-miR-548d-3p	HITS-CLIP	23313552
MIRT698472	hsa-miR-548h-3p	HITS-CLIP	23313552
MIRT698471	hsa-miR-548z	HITS-CLIP	23313552
MIRT698470	hsa-miR-548ae-3p	HITS-CLIP	23313552
MIRT698469	hsa-miR-548ah-3p	HITS-CLIP	23313552
MIRT698468	hsa-miR-548aj-3p	HITS-CLIP	23313552
MIRT698467	hsa-miR-548am-3p	HITS-CLIP	23313552
MIRT698466	hsa-miR-548aq-3p	HITS-CLIP	23313552
MIRT698465	hsa-miR-548j-3p	HITS-CLIP	23313552
MIRT698464	hsa-miR-548x-3p	HITS-CLIP	23313552
MIRT698463	hsa-miR-5582-3p	HITS-CLIP	23313552
MIRT698461	hsa-miR-5700	HITS-CLIP	23313552
MIRT698462	hsa-miR-4731-3p	HITS-CLIP	23313552
MIRT698460	hsa-miR-4801	HITS-CLIP	23313552
MIRT698459	hsa-miR-802	HITS-CLIP	23313552
MIRT553632	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT553631	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT553630	hsa-miR-107	PAR-CLIP	21572407
MIRT553629	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553628	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT553627	hsa-miR-383-3p	PAR-CLIP	21572407
MIRT553626	hsa-miR-194-5p	PAR-CLIP	21572407
MIRT553625	hsa-miR-4799-5p	PAR-CLIP	21572407
MIRT755766	hsa-miR-23a-3p	Luciferase reporter assay, Western blotting, Microarray, qRT-PCR, Immunohistochemistry (IHC), in vitro cullelar assays, Immunofluorescence, ELISA	37904170
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425747	hsa-miR-103b	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425749	hsa-miR-1305	CLIP-seq
MIRT1425750	hsa-miR-137	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425754	hsa-miR-153	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425756	hsa-miR-193a-3p	CLIP-seq
MIRT1425757	hsa-miR-193b	CLIP-seq
MIRT1425758	hsa-miR-200b	CLIP-seq
MIRT1425759	hsa-miR-200c	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT1425763	hsa-miR-3064-5p	CLIP-seq
MIRT1425764	hsa-miR-3133	CLIP-seq
MIRT1425765	hsa-miR-3200-3p	CLIP-seq
MIRT1425766	hsa-miR-337-3p	CLIP-seq
MIRT1425767	hsa-miR-3611	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT1425769	hsa-miR-3652	CLIP-seq
MIRT1425770	hsa-miR-3671	CLIP-seq
MIRT1425771	hsa-miR-369-3p	CLIP-seq
MIRT1425772	hsa-miR-374a	CLIP-seq
MIRT1425773	hsa-miR-374b	CLIP-seq
MIRT1425774	hsa-miR-376a	CLIP-seq
MIRT1425775	hsa-miR-376b	CLIP-seq
MIRT1425776	hsa-miR-3978	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT1425779	hsa-miR-429	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425781	hsa-miR-4430	CLIP-seq
MIRT1425782	hsa-miR-4501	CLIP-seq
MIRT1425783	hsa-miR-4503	CLIP-seq
MIRT1425784	hsa-miR-4505	CLIP-seq
MIRT1425785	hsa-miR-4519	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT1425787	hsa-miR-4670-3p	CLIP-seq
MIRT1425788	hsa-miR-4676-5p	CLIP-seq
MIRT1425789	hsa-miR-4699-3p	CLIP-seq
MIRT1425790	hsa-miR-4760-5p	CLIP-seq
MIRT1425791	hsa-miR-4773	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT1425795	hsa-miR-498	CLIP-seq
MIRT1425796	hsa-miR-501-3p	CLIP-seq
MIRT1425797	hsa-miR-502-3p	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT1425800	hsa-miR-548aa	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT1425802	hsa-miR-575	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT1425804	hsa-miR-592	CLIP-seq
MIRT1425805	hsa-miR-597	CLIP-seq
MIRT1425806	hsa-miR-607	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq
MIRT1425808	hsa-miR-892b	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT1425810	hsa-miR-1183	CLIP-seq
MIRT1425811	hsa-miR-1227	CLIP-seq
MIRT1425812	hsa-miR-1251	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT1425813	hsa-miR-142-3p	CLIP-seq
MIRT1425814	hsa-miR-323b-3p	CLIP-seq
MIRT1425815	hsa-miR-330-3p	CLIP-seq
MIRT1425816	hsa-miR-3545-5p	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT1425817	hsa-miR-4428	CLIP-seq
MIRT1425818	hsa-miR-4457	CLIP-seq
MIRT1425819	hsa-miR-4460	CLIP-seq
MIRT1425820	hsa-miR-455-5p	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT1425821	hsa-miR-4662a-5p	CLIP-seq
MIRT1425822	hsa-miR-4719	CLIP-seq
MIRT1425823	hsa-miR-4796-5p	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT1425824	hsa-miR-520d-5p	CLIP-seq
MIRT1425825	hsa-miR-524-5p	CLIP-seq
MIRT1425826	hsa-miR-548g	CLIP-seq
MIRT1425827	hsa-miR-548p	CLIP-seq
MIRT1425828	hsa-miR-556-5p	CLIP-seq
MIRT1425829	hsa-miR-610	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT1425810	hsa-miR-1183	CLIP-seq
MIRT1425811	hsa-miR-1227	CLIP-seq
MIRT2127555	hsa-miR-1228	CLIP-seq
MIRT2127556	hsa-miR-124	CLIP-seq
MIRT2127557	hsa-miR-1247	CLIP-seq
MIRT2127558	hsa-miR-1303	CLIP-seq
MIRT2127559	hsa-miR-132	CLIP-seq
MIRT2127560	hsa-miR-138	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT2127561	hsa-miR-141	CLIP-seq
MIRT1425813	hsa-miR-142-3p	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425756	hsa-miR-193a-3p	CLIP-seq
MIRT1425757	hsa-miR-193b	CLIP-seq
MIRT2127562	hsa-miR-200a	CLIP-seq
MIRT2127563	hsa-miR-212	CLIP-seq
MIRT2127564	hsa-miR-224	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT1425763	hsa-miR-3064-5p	CLIP-seq
MIRT2127565	hsa-miR-3123	CLIP-seq
MIRT2127566	hsa-miR-3140-3p	CLIP-seq
MIRT2127567	hsa-miR-3149	CLIP-seq
MIRT2127568	hsa-miR-335	CLIP-seq
MIRT2127569	hsa-miR-342-3p	CLIP-seq
MIRT1425816	hsa-miR-3545-5p	CLIP-seq
MIRT1425767	hsa-miR-3611	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT2127570	hsa-miR-3620	CLIP-seq
MIRT2127571	hsa-miR-362-5p	CLIP-seq
MIRT1425769	hsa-miR-3652	CLIP-seq
MIRT2127572	hsa-miR-3653	CLIP-seq
MIRT2127573	hsa-miR-3658	CLIP-seq
MIRT2127574	hsa-miR-3662	CLIP-seq
MIRT2127575	hsa-miR-3667-3p	CLIP-seq
MIRT1425771	hsa-miR-369-3p	CLIP-seq
MIRT2127576	hsa-miR-3713	CLIP-seq
MIRT2127577	hsa-miR-3714	CLIP-seq
MIRT1425772	hsa-miR-374a	CLIP-seq
MIRT1425773	hsa-miR-374b	CLIP-seq
MIRT2127578	hsa-miR-3910	CLIP-seq
MIRT2127579	hsa-miR-3922-5p	CLIP-seq
MIRT2127580	hsa-miR-3973	CLIP-seq
MIRT2127581	hsa-miR-412	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT2127582	hsa-miR-4289	CLIP-seq
MIRT1425781	hsa-miR-4430	CLIP-seq
MIRT1425819	hsa-miR-4460	CLIP-seq
MIRT1425782	hsa-miR-4501	CLIP-seq
MIRT1425783	hsa-miR-4503	CLIP-seq
MIRT1425784	hsa-miR-4505	CLIP-seq
MIRT2127583	hsa-miR-450b-5p	CLIP-seq
MIRT2127584	hsa-miR-4511	CLIP-seq
MIRT2127585	hsa-miR-4517	CLIP-seq
MIRT2127586	hsa-miR-4536	CLIP-seq
MIRT1425820	hsa-miR-455-5p	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT2127587	hsa-miR-4652-3p	CLIP-seq
MIRT1425787	hsa-miR-4670-3p	CLIP-seq
MIRT2127588	hsa-miR-4696	CLIP-seq
MIRT1425789	hsa-miR-4699-3p	CLIP-seq
MIRT2127589	hsa-miR-4704-3p	CLIP-seq
MIRT2127590	hsa-miR-4705	CLIP-seq
MIRT2127591	hsa-miR-4709-3p	CLIP-seq
MIRT2127592	hsa-miR-4709-5p	CLIP-seq
MIRT2127593	hsa-miR-4717-3p	CLIP-seq
MIRT2127594	hsa-miR-4718	CLIP-seq
MIRT1425822	hsa-miR-4719	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT2127595	hsa-miR-500b	CLIP-seq
MIRT1425796	hsa-miR-501-3p	CLIP-seq
MIRT2127596	hsa-miR-501-5p	CLIP-seq
MIRT1425797	hsa-miR-502-3p	CLIP-seq
MIRT2127597	hsa-miR-502-5p	CLIP-seq
MIRT2127598	hsa-miR-506	CLIP-seq
MIRT2127599	hsa-miR-511	CLIP-seq
MIRT1425824	hsa-miR-520d-5p	CLIP-seq
MIRT2127600	hsa-miR-520g	CLIP-seq
MIRT2127601	hsa-miR-520h	CLIP-seq
MIRT1425825	hsa-miR-524-5p	CLIP-seq
MIRT2127602	hsa-miR-544	CLIP-seq
MIRT2127603	hsa-miR-548b-3p	CLIP-seq
MIRT1425826	hsa-miR-548g	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT2127604	hsa-miR-555	CLIP-seq
MIRT2127605	hsa-miR-582-5p	CLIP-seq
MIRT2127606	hsa-miR-605	CLIP-seq
MIRT2127607	hsa-miR-616	CLIP-seq
MIRT2127608	hsa-miR-654-3p	CLIP-seq
MIRT1425808	hsa-miR-892b	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425747	hsa-miR-103b	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT1425810	hsa-miR-1183	CLIP-seq
MIRT2127555	hsa-miR-1228	CLIP-seq
MIRT2127556	hsa-miR-124	CLIP-seq
MIRT2127557	hsa-miR-1247	CLIP-seq
MIRT1425812	hsa-miR-1251	CLIP-seq
MIRT2349296	hsa-miR-1262	CLIP-seq
MIRT2349297	hsa-miR-1296	CLIP-seq
MIRT2127559	hsa-miR-132	CLIP-seq
MIRT2127560	hsa-miR-138	CLIP-seq
MIRT1425751	hsa-miR-140-5p	CLIP-seq
MIRT2127561	hsa-miR-141	CLIP-seq
MIRT1425813	hsa-miR-142-3p	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425754	hsa-miR-153	CLIP-seq
MIRT2349298	hsa-miR-185	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425756	hsa-miR-193a-3p	CLIP-seq
MIRT1425757	hsa-miR-193b	CLIP-seq
MIRT2127562	hsa-miR-200a	CLIP-seq
MIRT1425758	hsa-miR-200b	CLIP-seq
MIRT1425759	hsa-miR-200c	CLIP-seq
MIRT2127563	hsa-miR-212	CLIP-seq
MIRT2127564	hsa-miR-224	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT2349299	hsa-miR-2909	CLIP-seq
MIRT1425763	hsa-miR-3064-5p	CLIP-seq
MIRT2127565	hsa-miR-3123	CLIP-seq
MIRT2349300	hsa-miR-3127-5p	CLIP-seq
MIRT1425764	hsa-miR-3133	CLIP-seq
MIRT2127566	hsa-miR-3140-3p	CLIP-seq
MIRT2349301	hsa-miR-3146	CLIP-seq
MIRT2127567	hsa-miR-3149	CLIP-seq
MIRT2349302	hsa-miR-3163	CLIP-seq
MIRT2349303	hsa-miR-3177-5p	CLIP-seq
MIRT2349304	hsa-miR-3182	CLIP-seq
MIRT1425814	hsa-miR-323b-3p	CLIP-seq
MIRT1425815	hsa-miR-330-3p	CLIP-seq
MIRT2127568	hsa-miR-335	CLIP-seq
MIRT1425766	hsa-miR-337-3p	CLIP-seq
MIRT2127569	hsa-miR-342-3p	CLIP-seq
MIRT1425816	hsa-miR-3545-5p	CLIP-seq
MIRT1425767	hsa-miR-3611	CLIP-seq
MIRT1425768	hsa-miR-361-5p	CLIP-seq
MIRT2127570	hsa-miR-3620	CLIP-seq
MIRT2127571	hsa-miR-362-5p	CLIP-seq
MIRT1425769	hsa-miR-3652	CLIP-seq
MIRT2127572	hsa-miR-3653	CLIP-seq
MIRT2127573	hsa-miR-3658	CLIP-seq
MIRT2127574	hsa-miR-3662	CLIP-seq
MIRT2127575	hsa-miR-3667-3p	CLIP-seq
MIRT1425771	hsa-miR-369-3p	CLIP-seq
MIRT2127576	hsa-miR-3713	CLIP-seq
MIRT2127577	hsa-miR-3714	CLIP-seq
MIRT1425772	hsa-miR-374a	CLIP-seq
MIRT1425773	hsa-miR-374b	CLIP-seq
MIRT2127578	hsa-miR-3910	CLIP-seq
MIRT2349305	hsa-miR-3918	CLIP-seq
MIRT2127579	hsa-miR-3922-5p	CLIP-seq
MIRT2127580	hsa-miR-3973	CLIP-seq
MIRT1425776	hsa-miR-3978	CLIP-seq
MIRT2127581	hsa-miR-412	CLIP-seq
MIRT2349306	hsa-miR-4253	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425778	hsa-miR-4277	CLIP-seq
MIRT2127582	hsa-miR-4289	CLIP-seq
MIRT1425779	hsa-miR-429	CLIP-seq
MIRT2349307	hsa-miR-4302	CLIP-seq
MIRT2349308	hsa-miR-4306	CLIP-seq
MIRT2349309	hsa-miR-4307	CLIP-seq
MIRT2349310	hsa-miR-4310	CLIP-seq
MIRT2349311	hsa-miR-4314	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425781	hsa-miR-4430	CLIP-seq
MIRT2349312	hsa-miR-4436b-3p	CLIP-seq
MIRT1425819	hsa-miR-4460	CLIP-seq
MIRT1425782	hsa-miR-4501	CLIP-seq
MIRT1425783	hsa-miR-4503	CLIP-seq
MIRT1425784	hsa-miR-4505	CLIP-seq
MIRT2127584	hsa-miR-4511	CLIP-seq
MIRT1425785	hsa-miR-4519	CLIP-seq
MIRT1425786	hsa-miR-4637	CLIP-seq
MIRT2349313	hsa-miR-4644	CLIP-seq
MIRT2127587	hsa-miR-4652-3p	CLIP-seq
MIRT2349314	hsa-miR-4659a-3p	CLIP-seq
MIRT2349315	hsa-miR-4659b-3p	CLIP-seq
MIRT1425821	hsa-miR-4662a-5p	CLIP-seq
MIRT1425787	hsa-miR-4670-3p	CLIP-seq
MIRT1425788	hsa-miR-4676-5p	CLIP-seq
MIRT2349316	hsa-miR-4685-5p	CLIP-seq
MIRT2349317	hsa-miR-4688	CLIP-seq
MIRT2349318	hsa-miR-4698	CLIP-seq
MIRT1425789	hsa-miR-4699-3p	CLIP-seq
MIRT2349319	hsa-miR-4700-3p	CLIP-seq
MIRT2349320	hsa-miR-4701-3p	CLIP-seq
MIRT2127589	hsa-miR-4704-3p	CLIP-seq
MIRT2127590	hsa-miR-4705	CLIP-seq
MIRT2127592	hsa-miR-4709-5p	CLIP-seq
MIRT2127593	hsa-miR-4717-3p	CLIP-seq
MIRT2349321	hsa-miR-4717-5p	CLIP-seq
MIRT2127594	hsa-miR-4718	CLIP-seq
MIRT1425822	hsa-miR-4719	CLIP-seq
MIRT1425790	hsa-miR-4760-5p	CLIP-seq
MIRT2349322	hsa-miR-4761-3p	CLIP-seq
MIRT2349323	hsa-miR-4762-3p	CLIP-seq
MIRT2349324	hsa-miR-4768-3p	CLIP-seq
MIRT1425791	hsa-miR-4773	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT2349325	hsa-miR-494	CLIP-seq
MIRT1425794	hsa-miR-495	CLIP-seq
MIRT1425795	hsa-miR-498	CLIP-seq
MIRT2127595	hsa-miR-500b	CLIP-seq
MIRT1425796	hsa-miR-501-3p	CLIP-seq
MIRT2127596	hsa-miR-501-5p	CLIP-seq
MIRT1425797	hsa-miR-502-3p	CLIP-seq
MIRT2127597	hsa-miR-502-5p	CLIP-seq
MIRT2127598	hsa-miR-506	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT2127599	hsa-miR-511	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT1425824	hsa-miR-520d-5p	CLIP-seq
MIRT2127600	hsa-miR-520g	CLIP-seq
MIRT2127601	hsa-miR-520h	CLIP-seq
MIRT1425825	hsa-miR-524-5p	CLIP-seq
MIRT2127602	hsa-miR-544	CLIP-seq
MIRT2349326	hsa-miR-548ae	CLIP-seq
MIRT2349327	hsa-miR-548aj	CLIP-seq
MIRT2349328	hsa-miR-548am	CLIP-seq
MIRT2127603	hsa-miR-548b-3p	CLIP-seq
MIRT1425826	hsa-miR-548g	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT1425827	hsa-miR-548p	CLIP-seq
MIRT2349329	hsa-miR-548x	CLIP-seq
MIRT2127604	hsa-miR-555	CLIP-seq
MIRT2349330	hsa-miR-561	CLIP-seq
MIRT1425802	hsa-miR-575	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT2127605	hsa-miR-582-5p	CLIP-seq
MIRT2349331	hsa-miR-591	CLIP-seq
MIRT2127606	hsa-miR-605	CLIP-seq
MIRT2127607	hsa-miR-616	CLIP-seq
MIRT2349332	hsa-miR-618	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq
MIRT1425808	hsa-miR-892b	CLIP-seq
MIRT1425809	hsa-miR-1178	CLIP-seq
MIRT2127555	hsa-miR-1228	CLIP-seq
MIRT1425753	hsa-miR-145	CLIP-seq
MIRT1425755	hsa-miR-191	CLIP-seq
MIRT1425760	hsa-miR-23a	CLIP-seq
MIRT1425761	hsa-miR-23b	CLIP-seq
MIRT1425762	hsa-miR-23c	CLIP-seq
MIRT2349300	hsa-miR-3127-5p	CLIP-seq
MIRT2349306	hsa-miR-4253	CLIP-seq
MIRT2349309	hsa-miR-4307	CLIP-seq
MIRT2349317	hsa-miR-4688	CLIP-seq
MIRT2127589	hsa-miR-4704-3p	CLIP-seq
MIRT1425790	hsa-miR-4760-5p	CLIP-seq
MIRT1425792	hsa-miR-4774-5p	CLIP-seq
MIRT2349331	hsa-miR-591	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT1425801	hsa-miR-548m	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq
MIRT1425746	hsa-miR-101	CLIP-seq
MIRT1425748	hsa-miR-105	CLIP-seq
MIRT1425752	hsa-miR-144	CLIP-seq
MIRT1425777	hsa-miR-4264	CLIP-seq
MIRT1425780	hsa-miR-433	CLIP-seq
MIRT1425793	hsa-miR-4777-5p	CLIP-seq
MIRT1425798	hsa-miR-510	CLIP-seq
MIRT1425799	hsa-miR-512-5p	CLIP-seq
MIRT2349326	hsa-miR-548ae	CLIP-seq
MIRT2349327	hsa-miR-548aj	CLIP-seq
MIRT2349328	hsa-miR-548am	CLIP-seq
MIRT2349329	hsa-miR-548x	CLIP-seq
MIRT1425803	hsa-miR-577	CLIP-seq
MIRT1425807	hsa-miR-622	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
AR	Activation	18535113
HDAC1	Repression	20580679

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002102	Component	Podosome	IEA
GO:0005515	Function	Protein binding	IPI	9707407, 11042084, 11734628, 12023291, 12154091, 16944923, 17015620, 17724469, 18823282, 19332538, 20164257, 20850437, 21402783, 22262837, 23885123, 25753039, 28661558, 29366904, 30992345, 31473225, 33961781
GO:0005516	Function	Calmodulin binding	IEA
GO:0005737	Component	Cytoplasm	IDA	11734628
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	11090614, 18337546
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0005912	Component	Adherens junction	TAS	8486731
GO:0005921	Component	Gap junction	IEA
GO:0005921	Component	Gap junction	ISS
GO:0005923	Component	Bicellular tight junction	IBA
GO:0005923	Component	Bicellular tight junction	IDA	11734628, 14757759, 18823282, 22006950
GO:0005923	Component	Bicellular tight junction	IEA
GO:0005923	Component	Bicellular tight junction	TAS	8486731
GO:0007043	Process	Cell-cell junction assembly	TAS	8486731
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	29771433
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IDA	16427635
GO:0030036	Process	Actin cytoskeleton organization	IMP	25753039
GO:0030054	Component	Cell junction	IDA	28169360
GO:0030054	Component	Cell junction	TAS
GO:0030335	Process	Positive regulation of cell migration	IMP	25753039
GO:0031032	Process	Actomyosin structure organization	IMP	25753039
GO:0032991	Component	Protein-containing complex	IDA	25753039
GO:0034334	Process	Adherens junction maintenance	IMP	25753039
GO:0035633	Process	Maintenance of blood-brain barrier	NAS	30280653
GO:0036305	Process	Ameloblast differentiation	ISS
GO:0042995	Component	Cell projection	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	29771433
GO:0043296	Component	Apical junction complex	IDA	16427635
GO:0045177	Component	Apical part of cell	IDA	22006950
GO:0045216	Process	Cell-cell junction organization	IBA
GO:0045216	Process	Cell-cell junction organization	IMP	25753039
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0050839	Function	Cell adhesion molecule binding	IBA
GO:0051493	Process	Regulation of cytoskeleton organization	IMP	25753039
GO:0051497	Process	Negative regulation of stress fiber assembly	ISS
GO:0070160	Component	Tight junction	IDA	22855531, 27037668, 30734065
GO:0070160	Component	Tight junction	IMP	24854121
GO:0070161	Component	Anchoring junction	IEA
GO:0071896	Process	Protein localization to adherens junction	IMP	25753039
GO:0090557	Process	Establishment of endothelial intestinal barrier	IBA
GO:0090557	Process	Establishment of endothelial intestinal barrier	IMP	23885123
GO:0098609	Process	Cell-cell adhesion	IBA
GO:0150105	Process	Protein localization to cell-cell junction	IBA
GO:0150105	Process	Protein localization to cell-cell junction	IMP	25753039
GO:1901888	Process	Regulation of cell junction assembly	IMP	25753039
GO:1902396	Process	Protein localization to bicellular tight junction	IMP	25753039
GO:1903672	Process	Positive regulation of sprouting angiogenesis	IMP	25753039
GO:1905605	Process	Positive regulation of blood-brain barrier permeability	IBA
GO:1905605	Process	Positive regulation of blood-brain barrier permeability	IMP	24854121
GO:2000049	Process	Positive regulation of cell-cell adhesion mediated by cadherin	IMP	25753039
GO:2000810	Process	Regulation of bicellular tight junction assembly	IMP	25753039

Other IDs

• MIM: 601009
• HGNC: 11827
• e!Ensembl: ENSG00000104067

Protein

• UniProt ID: Q07157
• Protein name: Tight junction protein 1 (Tight junction protein ZO-1) (Zona occludens protein 1) (Zonula occludens protein 1)
• Protein function: TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:7798316, PubMed:9792688). Forms a
• PDB: 2H2B, 2H2C, 2H3M, 2JWE, 2KXR, 2KXS, 2RCZ, 3CYY, 3LH5, 3SHU, 3SHW, 3TSV, 3TSW, 3TSZ, 4OEO, 4OEP, 4Q2Q, 4YYX
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00595	PDZ	23 → 107	PDZ domain	Domain
  PF00595	PDZ	186 → 261	PDZ domain	Domain
  PF00595	PDZ	422 → 501	PDZ domain	Domain
  PF07653	SH3_2	520 → 582	Variant SH3 domain	Domain
  PF00625	Guanylate_kin	681 → 793	Guanylate kinase	Domain
  PF00791	ZU5	1635 → 1727	ZU5 domain	Family

• Tissue specificity: TISSUE SPECIFICITY: The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubu
• Sequence:

  MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVL
  KGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPD
  PEPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRERSLSPRSDRRSVASSQ
  PAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENM
  SLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHS
  GRSHDRPPRRSRSRSPDQRSEPSDHSRHSPQQPSNGSLRSRDEERISKPGAVSTPVKHAD
  DHTPKTVEEVTVERNEKQTPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRP
  SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIR
  EEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKG
  EVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRAD
  FWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREK
  LAREEPDIYQIAKSEPRDAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQ
  WYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMND
  GWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHT
  SDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSP
  QAQPQPIHRIDSPGFKPASQQKAEASSPVPYLSPETNPASSTSAVNHNVNLTNVRLEEPT
  PAPSTSYSPQADSLRTPSTEAAHIMLRDQEPSLSSHVDPTKVYRKDPYPEEMMRQNHVLK
  QPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQPTYRYESSSYTDQFSRNYEHRLRY
  EDRVPMYEEQWSYYDDKQPYPSRPPFDNQHSQDLDSRQHPEESSERGYFPRFEEPAPLSY
  DSRPRYEQAPRASALRHEEQPAPGYDTHGRLRPEAQPHPSAGPKPAESKQYFEQYSRSYE
  QVPPQGFTSRAGHFEPLHGAAAVPPLIPSSQHKPEALPSNTKPLPPPPTQTEEEEDPAMK
  PQSVLTRVKMFENKRSASLETKKDVNDTGSFKPPEVASKPSGAPIIGPKPTSQNQFSEHD
  KTLYRIPEPQKPQLKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFENKPPAHIAASHL
  SEPAKPAHSQNQSNFSSYSSKGKPPEADGVDRSFGEKRYEPIQATPPPPPLPSQYAQPSQ
  PVTSASLHIHSKGAHGEGNSVSLDFQNSLVSKPDPPPSQNKPATFRPPNREDTAQAAFYP
  QKSFPDKAPVNGTEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETAHK
  PDLSSKTPTSPKTLVKSHSLAQPPEFDSGVETFSIHAEKPKYQINNISTVPKAIPVSPSA
  VEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNS
  ILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANC
  VSVLIDHF

• Sequence length: 1748

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY	—	ClinGen, GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOMYOPATHY, DILATED	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESSENTIAL HYPERTENSION	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KERATOCONUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PELVIC ORGAN PROLAPSE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Primary dilated cardiomyopathy	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TJP1-related disorder	Uncertain significance; Likely benign; Benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	26543233		★☆☆☆☆ Found in Text Mining only
Adrenoleukodystrophy	Adrenoleukodystrophy	BEFREE	18162065		★☆☆☆☆ Found in Text Mining only
Anaplasia	Anaplasia	BEFREE	11369990		★☆☆☆☆ Found in Text Mining only
Angelman Syndrome	Angelman Syndrome	BEFREE	8825647		★☆☆☆☆ Found in Text Mining only
Arrhythmogenic Right Ventricular Dysplasia	Arrhythmogenic right ventricular cardiomyopathy	BEFREE	30354300		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Arthritis Infectious	Infective arthritis	Pubtator	18364044	Inhibit	★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	LHGDN	18418437		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	Pubtator	28901429	Stimulate	★☆☆☆☆ Found in Text Mining only
Azoospermia	Azoospermia	Pubtator	30243299	Associate	★☆☆☆☆ Found in Text Mining only
Biliary Atresia	Biliary atresia	Pubtator	34392560	Associate	★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	30061227		★☆☆☆☆ Found in Text Mining only
Bloom Syndrome	Bloom syndrome	Pubtator	36293204	Associate	★☆☆☆☆ Found in Text Mining only
Brain Edema	Brain edema	Pubtator	28490769	Associate	★☆☆☆☆ Found in Text Mining only
Breast adenocarcinoma	Breast Adenocarcinoma	BEFREE	24657059		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	9846967		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	11518717, 16140936, 22064657, 22193974, 24771004, 25733818, 26218882, 28683467, 30692208	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	19144824, 29115525	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	12708492, 25609232, 29776350, 34443536	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma in Situ	Carcinoma in situ	Pubtator	17217619	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	30061227		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	25027596		★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	19602254, 37790849	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	34216486	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	37240145	Inhibit	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	30409964		★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	Pubtator	18056766	Stimulate	★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	BEFREE	30354300		★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Dilated	Dilated cardiomyopathy	Pubtator	17760848	Inhibit	★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Dilated	Dilated cardiomyopathy	Pubtator	18056766	Stimulate	★☆☆☆☆ Found in Text Mining only
Cardiomyopathy, Dilated	Cardiomyopathy	BEFREE	30354300		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cataract	Cataract	Pubtator	33274006	Inhibit	★☆☆☆☆ Found in Text Mining only
Celiac Disease	Celiac disease	BEFREE	15191203, 21832836		★☆☆☆☆ Found in Text Mining only
Celiac Disease	Celiac disease	Pubtator	27446827	Associate	★☆☆☆☆ Found in Text Mining only
Cerebral Aneurysm	Cerebral Aneurysm	BEFREE	20577123		★☆☆☆☆ Found in Text Mining only
Cerebral Hemorrhage	Cerebral hemorrhage	Pubtator	29771433	Associate	★☆☆☆☆ Found in Text Mining only
Cerebrocostomandibular Syndrome	Cerebrocostomandibular syndrome	Pubtator	18056766	Associate	★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	30301260		★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	26306999		★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognitive disorder	BEFREE	29792953		★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	Pubtator	31418947	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	LHGDN	12708492		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	12708492, 29115525, 30892955, 34965023, 35218185	Associate	★☆☆☆☆ Found in Text Mining only
Congenital bilateral aplasia of vas deferens	Congenital bilateral absence of vas deferens	Pubtator	26277102	Associate	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	30765731	Inhibit	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	39201543	Associate	★☆☆☆☆ Found in Text Mining only
Cystitis Interstitial	Interstitial cystitis	Pubtator	21352500	Associate	★☆☆☆☆ Found in Text Mining only
Cystitis Interstitial	Interstitial cystitis	Pubtator	24445008	Inhibit	★☆☆☆☆ Found in Text Mining only
Deafness	Deafness	Pubtator	20505086	Associate	★☆☆☆☆ Found in Text Mining only
Dejerine-Sottas Disease (disorder)	Charcot-Marie-Tooth disease	BEFREE	28587416		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	31503404		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	21317917, 21832836, 30956991		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	17039425		★☆☆☆☆ Found in Text Mining only
DiGeorge Syndrome	DiGeorge Syndrome	LHGDN	15456900		★☆☆☆☆ Found in Text Mining only
Edema	Edema	Pubtator	29771433	Associate	★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	BEFREE	30981282		★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	31456452	Associate	★☆☆☆☆ Found in Text Mining only
Enterocolitis Necrotizing	Enterocolitis	Pubtator	29276042	Inhibit	★☆☆☆☆ Found in Text Mining only
Eosinophilic Esophagitis	Eosinophilia	Pubtator	29032661	Associate	★☆☆☆☆ Found in Text Mining only
Eosinophilic Esophagitis	Eosinophilia	Pubtator	35239721	Inhibit	★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty liver	Pubtator	30345259	Associate	★☆☆☆☆ Found in Text Mining only
Gastroesophageal Reflux	Gastroesophageal reflux disease	Pubtator	29032661	Associate	★☆☆☆☆ Found in Text Mining only
Glomerulosclerosis (disorder)	Glomerulosclerosis	BEFREE	29845705		★☆☆☆☆ Found in Text Mining only
Hashimoto Disease	Hashimoto disease	Pubtator	22878044, 29924048	Inhibit	★☆☆☆☆ Found in Text Mining only
Heart Failure	Heart failure	Pubtator	17760848, 18056766	Associate	★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	LHGDN	18056766		★☆☆☆☆ Found in Text Mining only
Hemolytic Uremic Syndrome	Hemolytic uremic syndrome	Pubtator	30301260	Inhibit	★☆☆☆☆ Found in Text Mining only
Hypercholesterolemia	Hypercholesterolemia	BEFREE	29428726		★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	27627890, 30755679, 33326735, 34162953, 36902491, 36982788	Inhibit	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	29769799	Associate	★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	29792953, 30601214		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	28545409		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	28545409	Associate	★☆☆☆☆ Found in Text Mining only
Intestinal Diseases	Intestinal disease	Pubtator	33381548	Associate	★☆☆☆☆ Found in Text Mining only
Intracranial Aneurysm	Intracranial aneurysm	Pubtator	33974072	Associate	★☆☆☆☆ Found in Text Mining only
Irritable Bowel Syndrome	Irritable bowel syndrome	Pubtator	23042942, 33750831, 33843785, 40141298	Associate	★☆☆☆☆ Found in Text Mining only
Irritable Bowel Syndrome	Irritable bowel syndrome	Pubtator	39551069	Inhibit	★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	11073823, 21775443, 24475278	Associate	★☆☆☆☆ Found in Text Mining only
Linear atrophy	Atrophy	BEFREE	28627704, 31470202		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	18386163		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25609232, 27750241, 29776350		★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	Pubtator	30692208	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	21586512, 25027596, 35767221	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	37240145	Inhibit	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	34216486	Associate	★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	23670122		★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin	Non-Hodgkin lymphoma	BEFREE	23670122		★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin, Familial	Lymphoma	BEFREE	23670122		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	9846967		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	30675248		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	25027596		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	30061227		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	17243118		★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	Pubtator	39628686	Associate	★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	LHGDN	15855653		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Melanoma	Pubtator	15855653, 36899895	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Meningioma	Meningioma	BEFREE	28870549		★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	30345259	Associate	★☆☆☆☆ Found in Text Mining only
Mouth Neoplasms	Mouth neoplasm	Pubtator	34534039	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	27132469		★☆☆☆☆ Found in Text Mining only
MYOTONIC DYSTROPHY 1	Myotonic dystrophy	BEFREE	31503404		★☆☆☆☆ Found in Text Mining only
Narcolepsy	Narcolepsy	GWASDB_DG	19629137		★☆☆☆☆ Found in Text Mining only
Nasal Polyps	Nasal polyp	Pubtator	31839751, 37224640, 37382248	Associate	★☆☆☆☆ Found in Text Mining only
Nasal Polyps	Nasal polyp	Pubtator	37047067	Inhibit	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25862830, 28011475, 31096007		★☆☆☆☆ Found in Text Mining only
Nephrosis Lipoid	Nephrotic syndrome	Pubtator	25683991	Associate	★☆☆☆☆ Found in Text Mining only
Neurofibrosarcoma	Neurofibrosarcoma	Pubtator	32590748	Associate	★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	24294375		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	29438631	Inhibit	★☆☆☆☆ Found in Text Mining only
Osteochondrodysplasias	Osteochondrodysplasias	Pubtator	33381548	Inhibit	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	35767221	Associate	★☆☆☆☆ Found in Text Mining only
Polycystic Kidney Diseases	Polycystic kidney disease	Pubtator	33974072	Inhibit	★☆☆☆☆ Found in Text Mining only
Proteinuria	Proteinuria	Pubtator	25683991	Associate	★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	Pubtator	19661441	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	25745049	Inhibit	★☆☆☆☆ Found in Text Mining only
Rhinitis Allergic	Rhinitis	Pubtator	35480562	Inhibit	★☆☆☆☆ Found in Text Mining only
Sarcoma Ewing	Sarcoma	Pubtator	15920547	Associate	★☆☆☆☆ Found in Text Mining only
Sarcoma Synovial	Synovial sarcoma	Pubtator	14704716	Associate	★☆☆☆☆ Found in Text Mining only
Sleep Apnea Obstructive	Sleep apnea	Pubtator	32647186	Inhibit	★☆☆☆☆ Found in Text Mining only
Small cell carcinoma of lung	Lung carcinoma	BEFREE	24959847		★☆☆☆☆ Found in Text Mining only
Small Cell Lung Carcinoma	Small cell lung carcinoma	Pubtator	24959847	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	37587724	Associate	★☆☆☆☆ Found in Text Mining only
Subarachnoid Hemorrhage	Subarachnoid hemorrhage	BEFREE	29855971		★☆☆☆☆ Found in Text Mining only
Tachycardia, Ventricular	Ventricular tachycardia	BEFREE	30354300		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasm	Thyroid Neoplasm	LHGDN	17962811		★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	28545409		★☆☆☆☆ Found in Text Mining only
Uremia	Uremia	Pubtator	30301260	Associate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	26800519, 33282635, 35087173	Associate	★☆☆☆☆ Found in Text Mining only
Urolithiasis	Urolithiasis	Pubtator	25329457	Inhibit	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	36088372	Associate	★☆☆☆☆ Found in Text Mining only
Uveal melanoma	Uveal melanoma	Pubtator	20861479	Associate	★☆☆☆☆ Found in Text Mining only