SUSD1 (sushi domain containing 1)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 64420
• Gene name: Sushi domain containing 1
• Gene symbol: SUSD1
• Synonyms (NCBI Gene): -
• Chromosome: 9
• Chromosome location: 9q31.3-q32

miRNA Show/Hide all (214)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023738	hsa-miR-1-3p	Microarray	18668037
MIRT722097	hsa-miR-7109-3p	HITS-CLIP	19536157
MIRT722096	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT722095	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT722094	hsa-miR-3120-5p	HITS-CLIP	19536157
MIRT722093	hsa-miR-3124-3p	HITS-CLIP	19536157
MIRT722092	hsa-miR-6830-3p	HITS-CLIP	19536157
MIRT722091	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT722090	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT722089	hsa-miR-6888-3p	HITS-CLIP	19536157
MIRT722088	hsa-miR-511-5p	HITS-CLIP	19536157
MIRT722087	hsa-miR-5699-3p	HITS-CLIP	19536157
MIRT722086	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT692640	hsa-miR-4643	HITS-CLIP	23313552
MIRT692639	hsa-miR-942-3p	HITS-CLIP	23313552
MIRT692638	hsa-miR-4781-3p	HITS-CLIP	23313552
MIRT692637	hsa-miR-4717-3p	HITS-CLIP	23313552
MIRT692636	hsa-miR-4716-5p	HITS-CLIP	23313552
MIRT692635	hsa-miR-3663-5p	HITS-CLIP	23313552
MIRT692634	hsa-miR-4635	HITS-CLIP	23313552
MIRT692633	hsa-miR-4755-3p	HITS-CLIP	23313552
MIRT692632	hsa-miR-6131	HITS-CLIP	23313552
MIRT692631	hsa-miR-548s	HITS-CLIP	23313552
MIRT692630	hsa-miR-4701-5p	HITS-CLIP	23313552
MIRT692629	hsa-miR-588	HITS-CLIP	23313552
MIRT692628	hsa-miR-4435	HITS-CLIP	23313552
MIRT692627	hsa-miR-3187-3p	HITS-CLIP	23313552
MIRT569241	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	20371350
MIRT569238	hsa-miR-5091	PAR-CLIP	20371350
MIRT569239	hsa-miR-6087	PAR-CLIP	20371350
MIRT569237	hsa-miR-139-3p	PAR-CLIP	20371350
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT569235	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569233	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT569232	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT569231	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT569230	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT569229	hsa-miR-6799-5p	PAR-CLIP	20371350
MIRT569228	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT569227	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT569226	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT569224	hsa-miR-1273h-5p	PAR-CLIP	20371350
MIRT569225	hsa-miR-30b-3p	PAR-CLIP	20371350
MIRT569223	hsa-miR-3689a-3p	PAR-CLIP	20371350
MIRT569222	hsa-miR-3689b-3p	PAR-CLIP	20371350
MIRT569221	hsa-miR-3689c	PAR-CLIP	20371350
MIRT569219	hsa-miR-6779-5p	PAR-CLIP	20371350
MIRT569220	hsa-miR-6780a-5p	PAR-CLIP	20371350
MIRT569218	hsa-miR-450a-1-3p	PAR-CLIP	20371350
MIRT569217	hsa-miR-3122	PAR-CLIP	20371350
MIRT569216	hsa-miR-3913-5p	PAR-CLIP	20371350
MIRT569215	hsa-miR-887-5p	PAR-CLIP	20371350
MIRT569214	hsa-miR-6513-5p	PAR-CLIP	20371350
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	26701625
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	26701625
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	26701625
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	26701625
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	26701625
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	26701625
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	26701625
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	26701625
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	26701625
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	26701625
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	26701625
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	26701625
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	27292025
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	27292025
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	27292025
MIRT722097	hsa-miR-7109-3p	HITS-CLIP	19536157
MIRT722096	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT722095	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT722094	hsa-miR-3120-5p	HITS-CLIP	19536157
MIRT722093	hsa-miR-3124-3p	HITS-CLIP	19536157
MIRT722092	hsa-miR-6830-3p	HITS-CLIP	19536157
MIRT722091	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT722090	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT722089	hsa-miR-6888-3p	HITS-CLIP	19536157
MIRT722088	hsa-miR-511-5p	HITS-CLIP	19536157
MIRT722087	hsa-miR-5699-3p	HITS-CLIP	19536157
MIRT722086	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT692640	hsa-miR-4643	HITS-CLIP	23313552
MIRT692639	hsa-miR-942-3p	HITS-CLIP	23313552
MIRT692638	hsa-miR-4781-3p	HITS-CLIP	23313552
MIRT692637	hsa-miR-4717-3p	HITS-CLIP	23313552
MIRT692636	hsa-miR-4716-5p	HITS-CLIP	23313552
MIRT692635	hsa-miR-3663-5p	HITS-CLIP	23313552
MIRT692634	hsa-miR-4635	HITS-CLIP	23313552
MIRT692633	hsa-miR-4755-3p	HITS-CLIP	23313552
MIRT692632	hsa-miR-6131	HITS-CLIP	23313552
MIRT692631	hsa-miR-548s	HITS-CLIP	23313552
MIRT692630	hsa-miR-4701-5p	HITS-CLIP	23313552
MIRT692629	hsa-miR-588	HITS-CLIP	23313552
MIRT692628	hsa-miR-4435	HITS-CLIP	23313552
MIRT692627	hsa-miR-3187-3p	HITS-CLIP	23313552
MIRT569241	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT569240	hsa-miR-6767-3p	PAR-CLIP	20371350
MIRT569238	hsa-miR-5091	PAR-CLIP	20371350
MIRT569239	hsa-miR-6087	PAR-CLIP	20371350
MIRT569237	hsa-miR-139-3p	PAR-CLIP	20371350
MIRT569236	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT569235	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT569234	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569233	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT569232	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT569231	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT569230	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT569229	hsa-miR-6799-5p	PAR-CLIP	20371350
MIRT569228	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT569227	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT569226	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT569224	hsa-miR-1273h-5p	PAR-CLIP	20371350
MIRT569225	hsa-miR-30b-3p	PAR-CLIP	20371350
MIRT569223	hsa-miR-3689a-3p	PAR-CLIP	20371350
MIRT569222	hsa-miR-3689b-3p	PAR-CLIP	20371350
MIRT569221	hsa-miR-3689c	PAR-CLIP	20371350
MIRT569219	hsa-miR-6779-5p	PAR-CLIP	20371350
MIRT569220	hsa-miR-6780a-5p	PAR-CLIP	20371350
MIRT569218	hsa-miR-450a-1-3p	PAR-CLIP	20371350
MIRT569217	hsa-miR-3122	PAR-CLIP	20371350
MIRT569216	hsa-miR-3913-5p	PAR-CLIP	20371350
MIRT569215	hsa-miR-887-5p	PAR-CLIP	20371350
MIRT569214	hsa-miR-6513-5p	PAR-CLIP	20371350
MIRT1403907	hsa-miR-106a	CLIP-seq
MIRT1403908	hsa-miR-106b	CLIP-seq
MIRT1403909	hsa-miR-1207-3p	CLIP-seq
MIRT1403910	hsa-miR-1273e	CLIP-seq
MIRT1403911	hsa-miR-1278	CLIP-seq
MIRT1403912	hsa-miR-17	CLIP-seq
MIRT1403913	hsa-miR-20a	CLIP-seq
MIRT1403914	hsa-miR-20b	CLIP-seq
MIRT1403915	hsa-miR-214	CLIP-seq
MIRT1403916	hsa-miR-297	CLIP-seq
MIRT1403917	hsa-miR-302a	CLIP-seq
MIRT1403918	hsa-miR-302b	CLIP-seq
MIRT1403919	hsa-miR-302c	CLIP-seq
MIRT1403920	hsa-miR-302d	CLIP-seq
MIRT1403921	hsa-miR-302e	CLIP-seq
MIRT1403922	hsa-miR-3609	CLIP-seq
MIRT1403923	hsa-miR-3614-3p	CLIP-seq
MIRT1403924	hsa-miR-3619-5p	CLIP-seq
MIRT1403925	hsa-miR-3622b-5p	CLIP-seq
MIRT1403926	hsa-miR-3668	CLIP-seq
MIRT1403927	hsa-miR-372	CLIP-seq
MIRT1403928	hsa-miR-373	CLIP-seq
MIRT1403929	hsa-miR-4263	CLIP-seq
MIRT1403930	hsa-miR-4434	CLIP-seq
MIRT1403931	hsa-miR-4496	CLIP-seq
MIRT1403932	hsa-miR-4509	CLIP-seq
MIRT1403933	hsa-miR-4516	CLIP-seq
MIRT1403934	hsa-miR-452	CLIP-seq
MIRT1403935	hsa-miR-4531	CLIP-seq
MIRT1403936	hsa-miR-4642	CLIP-seq
MIRT1403937	hsa-miR-4646-5p	CLIP-seq
MIRT1403938	hsa-miR-4676-3p	CLIP-seq
MIRT1403939	hsa-miR-4742-3p	CLIP-seq
MIRT1403940	hsa-miR-4744	CLIP-seq
MIRT1403941	hsa-miR-4796-3p	CLIP-seq
MIRT1403942	hsa-miR-4799-5p	CLIP-seq
MIRT1403943	hsa-miR-494	CLIP-seq
MIRT1403944	hsa-miR-519d	CLIP-seq
MIRT1403945	hsa-miR-520a-3p	CLIP-seq
MIRT1403946	hsa-miR-520b	CLIP-seq
MIRT1403947	hsa-miR-520c-3p	CLIP-seq
MIRT1403948	hsa-miR-520d-3p	CLIP-seq
MIRT1403949	hsa-miR-520e	CLIP-seq
MIRT1403950	hsa-miR-520f	CLIP-seq
MIRT1403951	hsa-miR-548ah	CLIP-seq
MIRT1403952	hsa-miR-548k	CLIP-seq
MIRT1403953	hsa-miR-548n	CLIP-seq
MIRT1403954	hsa-miR-567	CLIP-seq
MIRT1403955	hsa-miR-576-5p	CLIP-seq
MIRT1403956	hsa-miR-636	CLIP-seq
MIRT1403957	hsa-miR-761	CLIP-seq
MIRT1403958	hsa-miR-93	CLIP-seq
MIRT2121181	hsa-miR-28-5p	CLIP-seq
MIRT2121182	hsa-miR-3125	CLIP-seq
MIRT2121183	hsa-miR-3139	CLIP-seq
MIRT2121184	hsa-miR-3152-5p	CLIP-seq
MIRT2121185	hsa-miR-3916	CLIP-seq
MIRT2121186	hsa-miR-4774-3p	CLIP-seq
MIRT2121187	hsa-miR-518d-5p	CLIP-seq
MIRT2121188	hsa-miR-519b-5p	CLIP-seq
MIRT2121189	hsa-miR-519c-5p	CLIP-seq
MIRT2121190	hsa-miR-520c-5p	CLIP-seq
MIRT2121191	hsa-miR-526a	CLIP-seq
MIRT2121192	hsa-miR-708	CLIP-seq
MIRT2121193	hsa-miR-877	CLIP-seq
MIRT2343116	hsa-miR-128	CLIP-seq
MIRT2343117	hsa-miR-27a	CLIP-seq
MIRT2343118	hsa-miR-27b	CLIP-seq
MIRT1403916	hsa-miR-297	CLIP-seq
MIRT2121182	hsa-miR-3125	CLIP-seq
MIRT2343119	hsa-miR-3177-5p	CLIP-seq
MIRT1403923	hsa-miR-3614-3p	CLIP-seq
MIRT1403926	hsa-miR-3668	CLIP-seq
MIRT2121185	hsa-miR-3916	CLIP-seq
MIRT2343120	hsa-miR-4294	CLIP-seq
MIRT2343121	hsa-miR-4433	CLIP-seq
MIRT2343122	hsa-miR-4459	CLIP-seq
MIRT1403939	hsa-miR-4742-3p	CLIP-seq
MIRT2343123	hsa-miR-499-3p	CLIP-seq
MIRT2343124	hsa-miR-499a-3p	CLIP-seq
MIRT2343125	hsa-miR-513a-5p	CLIP-seq
MIRT1403954	hsa-miR-567	CLIP-seq
MIRT2637004	hsa-miR-4286	CLIP-seq
MIRT2637005	hsa-miR-4302	CLIP-seq
MIRT2637006	hsa-miR-4727-5p	CLIP-seq
MIRT2637007	hsa-miR-4769-3p	CLIP-seq
MIRT2637004	hsa-miR-4286	CLIP-seq
MIRT2637005	hsa-miR-4302	CLIP-seq
MIRT2637006	hsa-miR-4727-5p	CLIP-seq
MIRT2637007	hsa-miR-4769-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6UWL2
• Protein name: Sushi domain-containing protein 1
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00084	Sushi	239 → 294	Sushi repeat (SCR repeat)	Domain
  PF00084	Sushi	179 → 234	Sushi repeat (SCR repeat)	Domain
  PF07645	EGF_CA	125 → 174	Calcium-binding EGF domain	Domain
  PF07645	EGF_CA	73 → 115	Calcium-binding EGF domain	Domain
  PF18861	PTP_tm	606 → 746	Transmembrane domain of protein tyrosine phosphatase, receptor type J	Family

• Sequence:

  MGRGPWDAGPSRRLLPLLLLLGLARGAAGAPGPDGLDVCATCHEHATCQQREGKKICICN
  YGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCICLEGYRATNNNKTFIPNDG
  TFCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGYLPRNGPEPFHPTTDATSCTEIDCG
  TPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVSSCTGLGTWESPKLHCQEINCG
  NPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTEKGTWRESTLTCTEILTK
  INDVSLFNDTCVRWQINSRRINPKISYVISIKGQRLDPMESVREETVNLTTDSRTPEVCL
  ALYPGTNYTVNISTAPPRRSMPAVIGFQTAEVDLLEDDGSFNISIFNETCLKLNRRSRKV
  GSEHMYQFTVLGQRWYLANFSHATSFNFTTREQVPVVCLDLYPTTDYTVNVTLLRSPKRH
  SVQITIATPPAVKQTISNISGFNETCLRWRSIKTADMEEMYLFHIWGQRWYQKEFAQEMT
  FNISSSSRDPEVCLDLRPGTNYNVSLRALSSELPVVISLTTQITEPPLPEVEFFTVHRGP
  LPRLRLRKAKEKNGPISSYQVLVLPLALQSTFSCDSEGASSFFSNASDADGYVAAELLAK
  DVPDDAMEIPIGDRLYYGEYYNAPLKRGSDYCIILRITSEWNKVRRHSCAVWAQVKDSSL
  MLLQMAGVGLGSLAVVIILTFLSFSAV

• Sequence length: 747

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
AMYOTROPHIC LATERAL SCLEROSIS	—	GWAS catalog	17362836	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BRAIN ANEURYSM	—	GWAS catalog	30823506	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRIMARY DENTAL CARIES	—	GWAS catalog	34311721	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	23650146	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Intracranial Aneurysm	Intracranial Aneurysm	GWASCAT_DG	30823506		★☆☆☆☆ Found in Text Mining only
Venous Thromboembolism	Venous thromboembolism	Pubtator	23650146	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

Sort by: Blended Diseases Pathways Evidence source

CPNE4 2 shared diseasesBrain aneurysm, Dental caries 3 shared evidence sourcesGWAS catalog (Amyotrophic lateral sclerosis), GWAS catalog (Brain aneurysm), GWAS catalog (Dental caries) Related via 2 shared diseases including Brain aneurysm, Dental caries — evidence mostly GWAS catalog. MTMR3 2 shared diseasesBrain aneurysm, Dental caries 2 shared evidence sourcesGWAS catalog (Brain aneurysm), GWAS catalog (Dental caries) Related via 2 shared diseases including Brain aneurysm, Dental caries — evidence mostly GWAS catalog. PDZD2 2 shared diseasesBrain aneurysm, Dental caries 2 shared evidence sourcesGWAS catalog (Brain aneurysm), GWAS catalog (Dental caries) Related via 2 shared diseases including Brain aneurysm, Dental caries — evidence mostly GWAS catalog. ZNF746 1 shared diseaseBrain aneurysm 2 shared evidence sourcesGWAS catalog (Amyotrophic lateral sclerosis), GWAS catalog (Brain aneurysm) Related via 1 shared disease including Brain aneurysm — evidence mostly GWAS catalog. DSCAM 2 shared diseasesBrain aneurysm, Dental caries 2 shared evidence sourcesGWAS catalog (Brain aneurysm), GWAS catalog (Dental caries) Related via 2 shared diseases including Brain aneurysm, Dental caries — evidence mostly GWAS catalog.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
CPNE4	2	["Brain aneurysm","Dental caries"]	0	[]	3	["GWAS catalog (Amyotrophic lateral sclerosis)","GWAS catalog (Brain aneurysm)","GWAS catalog (Dental caries)"]
MTMR3	2	["Brain aneurysm","Dental caries"]	0	[]	2	["GWAS catalog (Brain aneurysm)","GWAS catalog (Dental caries)"]
PDZD2	2	["Brain aneurysm","Dental caries"]	0	[]	2	["GWAS catalog (Brain aneurysm)","GWAS catalog (Dental caries)"]
ZNF746	1	["Brain aneurysm"]	0	[]	2	["GWAS catalog (Amyotrophic lateral sclerosis)","GWAS catalog (Brain aneurysm)"]
DSCAM	2	["Brain aneurysm","Dental caries"]	0	[]	2	["GWAS catalog (Brain aneurysm)","GWAS catalog (Dental caries)"]

Diseases Linked via Similar Genes

Alzheimer disease Linked via 4 of 5 related genesCPNE4, MTMR3, PDZD2, DSCAM Diabetes mellitus type 2 Linked via 4 of 5 related genesCPNE4, MTMR3, ZNF746, DSCAM Color vision deficiency Linked via 3 of 5 related genesCPNE4, MTMR3, PDZD2 Dementia Linked via 2 of 5 related genesCPNE4, PDZD2 Lung cancer Linked via 2 of 5 related genesCPNE4, MTMR3

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Alzheimer disease	4	["CPNE4","MTMR3","PDZD2","DSCAM"]
Diabetes mellitus type 2	4	["CPNE4","MTMR3","ZNF746","DSCAM"]
Color vision deficiency	3	["CPNE4","MTMR3","PDZD2"]
Dementia	2	["CPNE4","PDZD2"]
Lung cancer	2	["CPNE4","MTMR3"]