SNX24 (sorting nexin 24)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 28966
• Gene name: Sorting nexin 24
• Gene symbol: SNX24
• Synonyms (NCBI Gene): PRO1284, SBBI31
• Chromosome: 5
• Chromosome location: 5q23.2

miRNA Show/Hide all (257)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027406	hsa-miR-98-5p	Microarray	19088304
MIRT437611	hsa-miR-145-5p	Microarray, qRT-PCR	22815788
MIRT437687	hsa-miR-223-3p	Microarray, qRT-PCR	22815788
MIRT437718	hsa-miR-29a-3p	Microarray, qRT-PCR	22815788
MIRT437719	hsa-miR-29b-3p	Microarray, qRT-PCR	22815788
MIRT437720	hsa-miR-29c-3p	Microarray, qRT-PCR	22815788
MIRT643042	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT643040	hsa-miR-5688	HITS-CLIP	23824327
MIRT643041	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT643039	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT643037	hsa-miR-4698	HITS-CLIP	23824327
MIRT643038	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT643036	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT643035	hsa-miR-552-5p	HITS-CLIP	23824327
MIRT094746	hsa-miR-651-3p	PAR-CLIP	22012620
MIRT526214	hsa-miR-32-3p	PAR-CLIP	22012620
MIRT526213	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT526212	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT526211	hsa-miR-4740-3p	PAR-CLIP	22012620
MIRT526210	hsa-miR-4693-3p	PAR-CLIP	22012620
MIRT526209	hsa-miR-4481	PAR-CLIP	22012620
MIRT526208	hsa-miR-4745-5p	PAR-CLIP	22012620
MIRT526207	hsa-miR-555	PAR-CLIP	22012620
MIRT526206	hsa-miR-340-5p	PAR-CLIP	22012620
MIRT526205	hsa-miR-6809-5p	PAR-CLIP	22012620
MIRT643037	hsa-miR-4698	HITS-CLIP	27418678
MIRT643042	hsa-miR-495-3p	HITS-CLIP	27418678
MIRT643040	hsa-miR-5688	HITS-CLIP	27418678
MIRT643042	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT643040	hsa-miR-5688	HITS-CLIP	23824327
MIRT643041	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT643039	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT643037	hsa-miR-4698	HITS-CLIP	23824327
MIRT643038	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT643036	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT643035	hsa-miR-552-5p	HITS-CLIP	23824327
MIRT094746	hsa-miR-651-3p	PAR-CLIP	22012620
MIRT526214	hsa-miR-32-3p	PAR-CLIP	22012620
MIRT526213	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT526212	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT526211	hsa-miR-4740-3p	PAR-CLIP	22012620
MIRT526210	hsa-miR-4693-3p	PAR-CLIP	22012620
MIRT526209	hsa-miR-4481	PAR-CLIP	22012620
MIRT526208	hsa-miR-4745-5p	PAR-CLIP	22012620
MIRT526207	hsa-miR-555	PAR-CLIP	22012620
MIRT526206	hsa-miR-340-5p	PAR-CLIP	22012620
MIRT526205	hsa-miR-6809-5p	PAR-CLIP	22012620
MIRT1377445	hsa-miR-1253	CLIP-seq
MIRT1377446	hsa-miR-1260	CLIP-seq
MIRT1377447	hsa-miR-1260b	CLIP-seq
MIRT1377448	hsa-miR-1273e	CLIP-seq
MIRT1377449	hsa-miR-142-3p	CLIP-seq
MIRT1377450	hsa-miR-1825	CLIP-seq
MIRT1377451	hsa-miR-188-3p	CLIP-seq
MIRT1377452	hsa-miR-1914	CLIP-seq
MIRT1377453	hsa-miR-1915	CLIP-seq
MIRT1377454	hsa-miR-196a	CLIP-seq
MIRT1377455	hsa-miR-196b	CLIP-seq
MIRT1377456	hsa-miR-1976	CLIP-seq
MIRT1377457	hsa-miR-203	CLIP-seq
MIRT1377458	hsa-miR-2052	CLIP-seq
MIRT1377459	hsa-miR-221	CLIP-seq
MIRT1377460	hsa-miR-222	CLIP-seq
MIRT1377461	hsa-miR-3065-5p	CLIP-seq
MIRT1377462	hsa-miR-3074-3p	CLIP-seq
MIRT1377463	hsa-miR-3119	CLIP-seq
MIRT1377464	hsa-miR-3120-3p	CLIP-seq
MIRT1377465	hsa-miR-3130-5p	CLIP-seq
MIRT1377466	hsa-miR-3156-3p	CLIP-seq
MIRT1377467	hsa-miR-3156-5p	CLIP-seq
MIRT1377468	hsa-miR-3171	CLIP-seq
MIRT1377469	hsa-miR-3200-3p	CLIP-seq
MIRT1377470	hsa-miR-323-3p	CLIP-seq
MIRT1377471	hsa-miR-3613-3p	CLIP-seq
MIRT1377472	hsa-miR-3614-5p	CLIP-seq
MIRT1377473	hsa-miR-362-5p	CLIP-seq
MIRT1377474	hsa-miR-365	CLIP-seq
MIRT1377475	hsa-miR-3658	CLIP-seq
MIRT1377476	hsa-miR-3682-5p	CLIP-seq
MIRT1377477	hsa-miR-383	CLIP-seq
MIRT1377478	hsa-miR-3927	CLIP-seq
MIRT1377479	hsa-miR-4276	CLIP-seq
MIRT1377480	hsa-miR-4293	CLIP-seq
MIRT1377481	hsa-miR-4328	CLIP-seq
MIRT1377482	hsa-miR-4482	CLIP-seq
MIRT1377483	hsa-miR-4539	CLIP-seq
MIRT1377484	hsa-miR-4653-3p	CLIP-seq
MIRT1377485	hsa-miR-4695-3p	CLIP-seq
MIRT1377486	hsa-miR-4697-3p	CLIP-seq
MIRT1377487	hsa-miR-4726-3p	CLIP-seq
MIRT1377488	hsa-miR-4757-5p	CLIP-seq
MIRT1377489	hsa-miR-4764-3p	CLIP-seq
MIRT1377490	hsa-miR-4772-5p	CLIP-seq
MIRT1377491	hsa-miR-487a	CLIP-seq
MIRT1377492	hsa-miR-495	CLIP-seq
MIRT1377493	hsa-miR-500b	CLIP-seq
MIRT1377494	hsa-miR-501-5p	CLIP-seq
MIRT1377495	hsa-miR-532-3p	CLIP-seq
MIRT1377496	hsa-miR-548n	CLIP-seq
MIRT1377497	hsa-miR-548t	CLIP-seq
MIRT1377498	hsa-miR-548v	CLIP-seq
MIRT1377499	hsa-miR-592	CLIP-seq
MIRT1377500	hsa-miR-596	CLIP-seq
MIRT1377501	hsa-miR-597	CLIP-seq
MIRT1377502	hsa-miR-629	CLIP-seq
MIRT1377503	hsa-miR-648	CLIP-seq
MIRT1377504	hsa-miR-663b	CLIP-seq
MIRT1377505	hsa-miR-671-3p	CLIP-seq
MIRT1377506	hsa-miR-671-5p	CLIP-seq
MIRT1377507	hsa-miR-888	CLIP-seq
MIRT2112346	hsa-miR-223	CLIP-seq
MIRT2112347	hsa-miR-23a	CLIP-seq
MIRT2112348	hsa-miR-23b	CLIP-seq
MIRT2112349	hsa-miR-23c	CLIP-seq
MIRT1377467	hsa-miR-3156-5p	CLIP-seq
MIRT2112350	hsa-miR-3662	CLIP-seq
MIRT2112351	hsa-miR-3691-5p	CLIP-seq
MIRT1377477	hsa-miR-383	CLIP-seq
MIRT2112352	hsa-miR-4252	CLIP-seq
MIRT2112353	hsa-miR-4656	CLIP-seq
MIRT2112354	hsa-miR-4659a-5p	CLIP-seq
MIRT2112355	hsa-miR-4659b-5p	CLIP-seq
MIRT1377486	hsa-miR-4697-3p	CLIP-seq
MIRT2112356	hsa-miR-4727-5p	CLIP-seq
MIRT2112357	hsa-miR-4752	CLIP-seq
MIRT2112358	hsa-miR-4764-5p	CLIP-seq
MIRT2112359	hsa-miR-4767	CLIP-seq
MIRT2112360	hsa-miR-4769-3p	CLIP-seq
MIRT1377490	hsa-miR-4772-5p	CLIP-seq
MIRT2112361	hsa-miR-4781-5p	CLIP-seq
MIRT1377496	hsa-miR-548n	CLIP-seq
MIRT1377497	hsa-miR-548t	CLIP-seq
MIRT2112362	hsa-miR-552	CLIP-seq
MIRT2112363	hsa-miR-744	CLIP-seq
MIRT1377457	hsa-miR-203	CLIP-seq
MIRT2112347	hsa-miR-23a	CLIP-seq
MIRT2112348	hsa-miR-23b	CLIP-seq
MIRT2112349	hsa-miR-23c	CLIP-seq
MIRT2335565	hsa-miR-412	CLIP-seq
MIRT2335566	hsa-miR-4274	CLIP-seq
MIRT2335567	hsa-miR-4519	CLIP-seq
MIRT2335568	hsa-miR-4524	CLIP-seq
MIRT1377485	hsa-miR-4695-3p	CLIP-seq
MIRT1377491	hsa-miR-487a	CLIP-seq
MIRT2629578	hsa-miR-103a	CLIP-seq
MIRT2629579	hsa-miR-107	CLIP-seq
MIRT2629580	hsa-miR-125a-5p	CLIP-seq
MIRT2629581	hsa-miR-125b	CLIP-seq
MIRT1377446	hsa-miR-1260	CLIP-seq
MIRT1377447	hsa-miR-1260b	CLIP-seq
MIRT2629582	hsa-miR-1272	CLIP-seq
MIRT1377448	hsa-miR-1273e	CLIP-seq
MIRT2629583	hsa-miR-1301	CLIP-seq
MIRT2629584	hsa-miR-1322	CLIP-seq
MIRT2629585	hsa-miR-134	CLIP-seq
MIRT1377450	hsa-miR-1825	CLIP-seq
MIRT1377451	hsa-miR-188-3p	CLIP-seq
MIRT1377452	hsa-miR-1914	CLIP-seq
MIRT1377453	hsa-miR-1915	CLIP-seq
MIRT1377456	hsa-miR-1976	CLIP-seq
MIRT1377458	hsa-miR-2052	CLIP-seq
MIRT2629586	hsa-miR-214	CLIP-seq
MIRT1377459	hsa-miR-221	CLIP-seq
MIRT1377460	hsa-miR-222	CLIP-seq
MIRT2112346	hsa-miR-223	CLIP-seq
MIRT2629587	hsa-miR-3118	CLIP-seq
MIRT1377463	hsa-miR-3119	CLIP-seq
MIRT1377465	hsa-miR-3130-5p	CLIP-seq
MIRT2629588	hsa-miR-3140-5p	CLIP-seq
MIRT1377466	hsa-miR-3156-3p	CLIP-seq
MIRT2629589	hsa-miR-3158-3p	CLIP-seq
MIRT2629590	hsa-miR-3164	CLIP-seq
MIRT2629591	hsa-miR-3168	CLIP-seq
MIRT1377471	hsa-miR-3613-3p	CLIP-seq
MIRT2629592	hsa-miR-3619-5p	CLIP-seq
MIRT2112350	hsa-miR-3662	CLIP-seq
MIRT1377476	hsa-miR-3682-5p	CLIP-seq
MIRT2629593	hsa-miR-3977	CLIP-seq
MIRT2629594	hsa-miR-4319	CLIP-seq
MIRT2629595	hsa-miR-4427	CLIP-seq
MIRT1377482	hsa-miR-4482	CLIP-seq
MIRT2629596	hsa-miR-4495	CLIP-seq
MIRT2629597	hsa-miR-4509	CLIP-seq
MIRT2112354	hsa-miR-4659a-5p	CLIP-seq
MIRT2112355	hsa-miR-4659b-5p	CLIP-seq
MIRT2629598	hsa-miR-4662a-5p	CLIP-seq
MIRT2629599	hsa-miR-4690-5p	CLIP-seq
MIRT1377486	hsa-miR-4697-3p	CLIP-seq
MIRT1377487	hsa-miR-4726-3p	CLIP-seq
MIRT2629600	hsa-miR-4744	CLIP-seq
MIRT1377488	hsa-miR-4757-5p	CLIP-seq
MIRT2629601	hsa-miR-4760-5p	CLIP-seq
MIRT2629602	hsa-miR-4793-5p	CLIP-seq
MIRT2629603	hsa-miR-4799-5p	CLIP-seq
MIRT1377491	hsa-miR-487a	CLIP-seq
MIRT2629604	hsa-miR-496	CLIP-seq
MIRT2629605	hsa-miR-498	CLIP-seq
MIRT2629606	hsa-miR-5047	CLIP-seq
MIRT2629607	hsa-miR-548aa	CLIP-seq
MIRT2629608	hsa-miR-548c-3p	CLIP-seq
MIRT1377496	hsa-miR-548n	CLIP-seq
MIRT1377497	hsa-miR-548t	CLIP-seq
MIRT1377498	hsa-miR-548v	CLIP-seq
MIRT2629609	hsa-miR-549	CLIP-seq
MIRT2629610	hsa-miR-561	CLIP-seq
MIRT2629611	hsa-miR-617	CLIP-seq
MIRT1377502	hsa-miR-629	CLIP-seq
MIRT1377504	hsa-miR-663b	CLIP-seq
MIRT1377506	hsa-miR-671-5p	CLIP-seq
MIRT2629612	hsa-miR-761	CLIP-seq
MIRT2629613	hsa-miR-885-3p	CLIP-seq
MIRT2629614	hsa-miR-891b	CLIP-seq
MIRT2629580	hsa-miR-125a-5p	CLIP-seq
MIRT2629581	hsa-miR-125b	CLIP-seq
MIRT2629582	hsa-miR-1272	CLIP-seq
MIRT2629584	hsa-miR-1322	CLIP-seq
MIRT2629585	hsa-miR-134	CLIP-seq
MIRT1377450	hsa-miR-1825	CLIP-seq
MIRT1377452	hsa-miR-1914	CLIP-seq
MIRT1377453	hsa-miR-1915	CLIP-seq
MIRT1377456	hsa-miR-1976	CLIP-seq
MIRT1377458	hsa-miR-2052	CLIP-seq
MIRT1377459	hsa-miR-221	CLIP-seq
MIRT1377460	hsa-miR-222	CLIP-seq
MIRT2629587	hsa-miR-3118	CLIP-seq
MIRT1377463	hsa-miR-3119	CLIP-seq
MIRT1377465	hsa-miR-3130-5p	CLIP-seq
MIRT2629589	hsa-miR-3158-3p	CLIP-seq
MIRT2629590	hsa-miR-3164	CLIP-seq
MIRT1377472	hsa-miR-3614-5p	CLIP-seq
MIRT2691712	hsa-miR-3651	CLIP-seq
MIRT2112350	hsa-miR-3662	CLIP-seq
MIRT1377476	hsa-miR-3682-5p	CLIP-seq
MIRT2629593	hsa-miR-3977	CLIP-seq
MIRT1377480	hsa-miR-4293	CLIP-seq
MIRT2629594	hsa-miR-4319	CLIP-seq
MIRT1377482	hsa-miR-4482	CLIP-seq
MIRT2629596	hsa-miR-4495	CLIP-seq
MIRT2629597	hsa-miR-4509	CLIP-seq
MIRT2112354	hsa-miR-4659a-5p	CLIP-seq
MIRT2112355	hsa-miR-4659b-5p	CLIP-seq
MIRT1377487	hsa-miR-4726-3p	CLIP-seq
MIRT2629600	hsa-miR-4744	CLIP-seq
MIRT1377488	hsa-miR-4757-5p	CLIP-seq
MIRT2629602	hsa-miR-4793-5p	CLIP-seq
MIRT2629603	hsa-miR-4799-5p	CLIP-seq
MIRT2629604	hsa-miR-496	CLIP-seq
MIRT2629605	hsa-miR-498	CLIP-seq
MIRT2629608	hsa-miR-548c-3p	CLIP-seq
MIRT1377498	hsa-miR-548v	CLIP-seq
MIRT1377500	hsa-miR-596	CLIP-seq
MIRT2629611	hsa-miR-617	CLIP-seq
MIRT1377502	hsa-miR-629	CLIP-seq
MIRT1377504	hsa-miR-663b	CLIP-seq
MIRT1377506	hsa-miR-671-5p	CLIP-seq
MIRT2629613	hsa-miR-885-3p	CLIP-seq
MIRT2629614	hsa-miR-891b	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0008289	Function	Lipid binding	IEA
GO:0010314	Function	Phosphatidylinositol-5-phosphate binding	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0030659	Component	Cytoplasmic vesicle membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	IEA
GO:0035091	Function	Phosphatidylinositol binding	IEA
GO:0070273	Function	Phosphatidylinositol-4-phosphate binding	IEA
GO:1901981	Function	Phosphatidylinositol phosphate binding	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9Y343
• Protein name: Sorting nexin-24
• Protein function: May be involved in several stages of intracellular trafficking.
• PDB: 4AZ9 , 8TBV , 8TBW , 8U9G
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00787	PX	26 → 103	PX domain	Domain

• Sequence:

  MEVYIPSFRYEESDLERGYTVFKIEVLMNGRKHFVEKRYSEFHALHKKLKKCIKTPEIPS
  KHVRNWVPKVLEQRRQGLETYLQAVILENEELPKLFLDFLNVRHLPSLPKAESCGSFDET
  ESEESSKLSHQPVLLFLRDPYVLPAASDFPNVVIEGVLHGIFYPHLQPR

• Sequence length: 169

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
DIVERTICULAR DISEASE	—	GWAS catalog	30177863, 37492107	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER	—	GWAS catalog	23793025, 34294844, 35115687	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OCULAR HYPOTENSION	—	GWAS catalog	39024449	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Diverticular Diseases	Diverticular Diseases	GWASCAT_DG	30177863		★☆☆☆☆ Found in Text Mining only

Related Genes

PCSK5 2 shared diseasesDiverticular disease, Ocular hypotension 2 shared evidence sourcesGWAS catalog (Diverticular disease), GWAS catalog (Ocular hypotension) Related via 2 shared diseases including Diverticular disease, Ocular hypotension — evidence mostly GWAS catalog.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
PCSK5	2	["Diverticular disease","Ocular hypotension"]	0	[]	2	["GWAS catalog (Diverticular disease)","GWAS catalog (Ocular hypotension)"]

Diseases Linked via Similar Genes

Alzheimer disease Linked via 1 of 1 related genePCSK5 Amyotrophic lateral sclerosis Linked via 1 of 1 related genePCSK5 Ankylosing spondylitis Linked via 1 of 1 related genePCSK5 Imperforate anus Linked via 1 of 1 related genePCSK5 Astrocytoma Linked via 1 of 1 related genePCSK5

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Alzheimer disease	1	["PCSK5"]
Amyotrophic lateral sclerosis	1	["PCSK5"]
Ankylosing spondylitis	1	["PCSK5"]
Imperforate anus	1	["PCSK5"]
Astrocytoma	1	["PCSK5"]