SNAPC1 (small nuclear RNA activating complex polypeptide 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 6617 |
| Gene name | Small nuclear RNA activating complex polypeptide 1 |
| Gene symbol | SNAPC1 |
| Synonyms (NCBI Gene) |
PTFgammaSNAP43
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| Chromosome | 14 |
| Chromosome location | 14q23.2 |
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miRNA
miRNA information provided by mirtarbase database.
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q16533 | ||||||||||
| Protein name | snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE-binding factor subunit gamma) (PTF subunit gamma) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activati | ||||||||||
| Protein function | Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TB | ||||||||||
| PDB | 7XUR , 7ZWC , 7ZWD , 7ZX7 , 7ZX8 , 7ZXE , 8ITY , 8IUE , 8IUH , 9FSO , 9FSP , 9FSQ , 9FSR , 9FSS | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MGTPPGLQTDCEALLSRFQETDSVRFEDFTELWRNMKFGTIFCGRMRNLEKNMFTKEALA |
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| Sequence length | 368 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with SNAPC1 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to SNAPC1 (see Related Genes above), that are NOT already directly curated for SNAPC1 itself -- a lead worth checking, not a confirmed association.
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