SIGLEC9 (sialic acid binding Ig like lectin 9)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 27180
• Gene name: Sialic acid binding Ig like lectin 9
• Gene symbol: SIGLEC9
• Synonyms (NCBI Gene): CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9
• Chromosome: 19
• Chromosome location: 19q13.41

miRNA Show/Hide all (302)

miRTarBase ID	miRNA	Experiments	Reference
MIRT650231	hsa-miR-508-5p	HITS-CLIP	19536157
MIRT650229	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT650224	hsa-miR-4793-3p	HITS-CLIP	19536157
MIRT650222	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT650221	hsa-miR-6086	HITS-CLIP	19536157
MIRT650220	hsa-miR-6499-3p	HITS-CLIP	19536157
MIRT650219	hsa-miR-4252	HITS-CLIP	19536157
MIRT650212	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT650211	hsa-miR-7703	HITS-CLIP	19536157
MIRT650210	hsa-miR-455-3p	HITS-CLIP	19536157
MIRT650208	hsa-miR-6516-5p	HITS-CLIP	19536157
MIRT711830	hsa-miR-652-5p	HITS-CLIP	19536157
MIRT711829	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT711828	hsa-miR-2681-5p	HITS-CLIP	19536157
MIRT621246	hsa-miR-562	HITS-CLIP	23313552
MIRT621245	hsa-miR-5571-5p	HITS-CLIP	23313552
MIRT621244	hsa-miR-451b	HITS-CLIP	23313552
MIRT621243	hsa-miR-4759	HITS-CLIP	23313552
MIRT621242	hsa-miR-5697	HITS-CLIP	23313552
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23313552
MIRT621240	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT621239	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT621238	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT621236	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT621235	hsa-miR-1976	HITS-CLIP	23313552
MIRT632073	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT621234	hsa-miR-4279	HITS-CLIP	23313552
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621240	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT621239	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT621238	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT621236	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621235	hsa-miR-1976	HITS-CLIP	23824327
MIRT650232	hsa-miR-504-5p	HITS-CLIP	23824327
MIRT650231	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT650230	hsa-miR-3940-3p	HITS-CLIP	23824327
MIRT650207	hsa-miR-4459	HITS-CLIP	23824327
MIRT650229	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT650228	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT650227	hsa-miR-4308	HITS-CLIP	23824327
MIRT650226	hsa-miR-4254	HITS-CLIP	23824327
MIRT650225	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT650224	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT650223	hsa-miR-6087	HITS-CLIP	23824327
MIRT650222	hsa-miR-377-5p	HITS-CLIP	23824327
MIRT650221	hsa-miR-6086	HITS-CLIP	23824327
MIRT650220	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT650219	hsa-miR-4252	HITS-CLIP	23824327
MIRT650218	hsa-miR-658	HITS-CLIP	23824327
MIRT650217	hsa-miR-3612	HITS-CLIP	23824327
MIRT650216	hsa-miR-650	HITS-CLIP	23824327
MIRT664991	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT650215	hsa-miR-25-5p	HITS-CLIP	23824327
MIRT650214	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT650213	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT650212	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT650211	hsa-miR-7703	HITS-CLIP	23824327
MIRT650210	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT650209	hsa-miR-4443	HITS-CLIP	23824327
MIRT650208	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT650233	hsa-miR-6732-3p	HITS-CLIP	23824327
MIRT650232	hsa-miR-504-5p	HITS-CLIP	23824327
MIRT650231	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT650230	hsa-miR-3940-3p	HITS-CLIP	23824327
MIRT650229	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT650228	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT650227	hsa-miR-4308	HITS-CLIP	23824327
MIRT650226	hsa-miR-4254	HITS-CLIP	23824327
MIRT650225	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT650224	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT650223	hsa-miR-6087	HITS-CLIP	23824327
MIRT650222	hsa-miR-377-5p	HITS-CLIP	23824327
MIRT650221	hsa-miR-6086	HITS-CLIP	23824327
MIRT650220	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT650219	hsa-miR-4252	HITS-CLIP	23824327
MIRT650218	hsa-miR-658	HITS-CLIP	23824327
MIRT650217	hsa-miR-3612	HITS-CLIP	23824327
MIRT650216	hsa-miR-650	HITS-CLIP	23824327
MIRT650215	hsa-miR-25-5p	HITS-CLIP	23824327
MIRT650214	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT650213	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT650212	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT650211	hsa-miR-7703	HITS-CLIP	23824327
MIRT650210	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT650209	hsa-miR-4443	HITS-CLIP	23824327
MIRT650208	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT650207	hsa-miR-4459	HITS-CLIP	23824327
MIRT637944	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT637943	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT637942	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT637941	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT637940	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT632073	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621245	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621240	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT621239	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT621238	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT621236	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621235	hsa-miR-1976	HITS-CLIP	23824327
MIRT621234	hsa-miR-4279	HITS-CLIP	23824327
MIRT545609	hsa-miR-3133	PAR-CLIP	21572407
MIRT545608	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT545607	hsa-miR-583	PAR-CLIP	21572407
MIRT545606	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT545605	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT545604	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT545603	hsa-miR-4649-3p	PAR-CLIP	21572407
MIRT545602	hsa-miR-6861-5p	PAR-CLIP	21572407
MIRT545601	hsa-miR-3975	PAR-CLIP	21572407
MIRT545599	hsa-miR-2467-5p	PAR-CLIP	21572407
MIRT545600	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT545597	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT545598	hsa-miR-3188	PAR-CLIP	21572407
MIRT545595	hsa-miR-5589-5p	PAR-CLIP	21572407
MIRT545596	hsa-miR-4505	PAR-CLIP	21572407
MIRT545594	hsa-miR-5787	PAR-CLIP	21572407
MIRT545593	hsa-miR-555	PAR-CLIP	21572407
MIRT545592	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT621235	hsa-miR-1976	PAR-CLIP	27292025
MIRT621236	hsa-miR-3653-5p	PAR-CLIP	27292025
MIRT621234	hsa-miR-4279	PAR-CLIP	27292025
MIRT621240	hsa-miR-4722-3p	PAR-CLIP	27292025
MIRT621245	hsa-miR-5571-5p	PAR-CLIP	27292025
MIRT621239	hsa-miR-6727-3p	PAR-CLIP	27292025
MIRT621238	hsa-miR-6747-3p	PAR-CLIP	27292025
MIRT632073	hsa-miR-6778-3p	PAR-CLIP	27292025
MIRT637940	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT637942	hsa-miR-514a-3p	HITS-CLIP	27418678
MIRT637941	hsa-miR-514b-3p	HITS-CLIP	27418678
MIRT637944	hsa-miR-642a-3p	HITS-CLIP	27418678
MIRT637943	hsa-miR-642b-3p	HITS-CLIP	27418678
MIRT650231	hsa-miR-508-5p	HITS-CLIP	19536157
MIRT650229	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT650224	hsa-miR-4793-3p	HITS-CLIP	19536157
MIRT650222	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT650221	hsa-miR-6086	HITS-CLIP	19536157
MIRT650220	hsa-miR-6499-3p	HITS-CLIP	19536157
MIRT650219	hsa-miR-4252	HITS-CLIP	19536157
MIRT650212	hsa-miR-6807-5p	HITS-CLIP	19536157
MIRT650211	hsa-miR-7703	HITS-CLIP	19536157
MIRT650210	hsa-miR-455-3p	HITS-CLIP	19536157
MIRT650208	hsa-miR-6516-5p	HITS-CLIP	19536157
MIRT711830	hsa-miR-652-5p	HITS-CLIP	19536157
MIRT711829	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT711828	hsa-miR-2681-5p	HITS-CLIP	19536157
MIRT621246	hsa-miR-562	HITS-CLIP	23313552
MIRT621245	hsa-miR-5571-5p	HITS-CLIP	23313552
MIRT621244	hsa-miR-451b	HITS-CLIP	23313552
MIRT621243	hsa-miR-4759	HITS-CLIP	23313552
MIRT621242	hsa-miR-5697	HITS-CLIP	23313552
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23313552
MIRT621240	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT621239	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT621238	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT621236	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT621235	hsa-miR-1976	HITS-CLIP	23313552
MIRT632073	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT621234	hsa-miR-4279	HITS-CLIP	23313552
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621240	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT621239	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT621238	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT621236	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621235	hsa-miR-1976	HITS-CLIP	23824327
MIRT650232	hsa-miR-504-5p	HITS-CLIP	23824327
MIRT650231	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT650230	hsa-miR-3940-3p	HITS-CLIP	23824327
MIRT650207	hsa-miR-4459	HITS-CLIP	23824327
MIRT650229	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT650228	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT650227	hsa-miR-4308	HITS-CLIP	23824327
MIRT650226	hsa-miR-4254	HITS-CLIP	23824327
MIRT650225	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT650224	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT650223	hsa-miR-6087	HITS-CLIP	23824327
MIRT650222	hsa-miR-377-5p	HITS-CLIP	23824327
MIRT650221	hsa-miR-6086	HITS-CLIP	23824327
MIRT650220	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT650219	hsa-miR-4252	HITS-CLIP	23824327
MIRT650218	hsa-miR-658	HITS-CLIP	23824327
MIRT650217	hsa-miR-3612	HITS-CLIP	23824327
MIRT650216	hsa-miR-650	HITS-CLIP	23824327
MIRT664991	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT650215	hsa-miR-25-5p	HITS-CLIP	23824327
MIRT650214	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT650213	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT650212	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT650211	hsa-miR-7703	HITS-CLIP	23824327
MIRT650210	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT650209	hsa-miR-4443	HITS-CLIP	23824327
MIRT650208	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT650233	hsa-miR-6732-3p	HITS-CLIP	23824327
MIRT650232	hsa-miR-504-5p	HITS-CLIP	23824327
MIRT650231	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT650230	hsa-miR-3940-3p	HITS-CLIP	23824327
MIRT650229	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT650228	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT650227	hsa-miR-4308	HITS-CLIP	23824327
MIRT650226	hsa-miR-4254	HITS-CLIP	23824327
MIRT650225	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT650224	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT650223	hsa-miR-6087	HITS-CLIP	23824327
MIRT650222	hsa-miR-377-5p	HITS-CLIP	23824327
MIRT650221	hsa-miR-6086	HITS-CLIP	23824327
MIRT650220	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT650219	hsa-miR-4252	HITS-CLIP	23824327
MIRT650218	hsa-miR-658	HITS-CLIP	23824327
MIRT650217	hsa-miR-3612	HITS-CLIP	23824327
MIRT650216	hsa-miR-650	HITS-CLIP	23824327
MIRT650215	hsa-miR-25-5p	HITS-CLIP	23824327
MIRT650214	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT650213	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT650212	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT650211	hsa-miR-7703	HITS-CLIP	23824327
MIRT650210	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT650209	hsa-miR-4443	HITS-CLIP	23824327
MIRT650208	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT650207	hsa-miR-4459	HITS-CLIP	23824327
MIRT637944	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT637943	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT637942	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT637941	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT637940	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT632073	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT621246	hsa-miR-562	HITS-CLIP	23824327
MIRT621245	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT621244	hsa-miR-451b	HITS-CLIP	23824327
MIRT621243	hsa-miR-4759	HITS-CLIP	23824327
MIRT621242	hsa-miR-5697	HITS-CLIP	23824327
MIRT621241	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT621240	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT621239	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT621238	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT621237	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT621236	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT621235	hsa-miR-1976	HITS-CLIP	23824327
MIRT621234	hsa-miR-4279	HITS-CLIP	23824327
MIRT545609	hsa-miR-3133	PAR-CLIP	21572407
MIRT545608	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT545607	hsa-miR-583	PAR-CLIP	21572407
MIRT545606	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT545605	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT545604	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT545603	hsa-miR-4649-3p	PAR-CLIP	21572407
MIRT545602	hsa-miR-6861-5p	PAR-CLIP	21572407
MIRT545601	hsa-miR-3975	PAR-CLIP	21572407
MIRT545599	hsa-miR-2467-5p	PAR-CLIP	21572407
MIRT545600	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT545597	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT545598	hsa-miR-3188	PAR-CLIP	21572407
MIRT545595	hsa-miR-5589-5p	PAR-CLIP	21572407
MIRT545596	hsa-miR-4505	PAR-CLIP	21572407
MIRT545594	hsa-miR-5787	PAR-CLIP	21572407
MIRT545593	hsa-miR-555	PAR-CLIP	21572407
MIRT545592	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT1348633	hsa-miR-218	CLIP-seq
MIRT1348634	hsa-miR-3140-3p	CLIP-seq
MIRT1348635	hsa-miR-4509	CLIP-seq
MIRT1348636	hsa-miR-4639-3p	CLIP-seq
MIRT1348637	hsa-miR-4744	CLIP-seq
MIRT1348638	hsa-miR-5096	CLIP-seq
MIRT1348639	hsa-miR-636	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25187624, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	NAS	10801860
GO:0005886	Component	Plasma membrane	TAS
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007166	Process	Cell surface receptor signaling pathway	NAS	10801860
GO:0016020	Component	Membrane	IEA
GO:0030246	Function	Carbohydrate binding	IEA
GO:0030246	Function	Carbohydrate binding	NAS	10801860
GO:0030667	Component	Secretory granule membrane	TAS
GO:0033691	Function	Sialic acid binding	IBA

Other IDs

• MIM: 605640
• HGNC: 10878
• e!Ensembl: ENSG00000129450

Protein

• UniProt ID: Q9Y336
• Protein name: Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329)
• Protein function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	24 → 140	Immunoglobulin V-set domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate,
• Sequence:

  MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGY
  WFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFR
  MEKGSIKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISW
  IGTSVSPLDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLT
  MTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPS
  NPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQSKATSGVTQGVVGGAGATALVF
  LSFCVIFVVVRSCRKKSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPA
  SARSSVGEGELQYASLSFQMVKPWDSRGQEATDTEYSEIKIHR

• Sequence length: 463

Pathways

KEGG Pathway	Reactome Pathway
Neutrophil extracellular trap formation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
	Neutrophil degranulation

Related Genes

Sort by: Blended Diseases Pathways Evidence source

FCGR3A 2 shared pathwaysNeutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Related via 2 shared pathways including Neutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. ITGAL 2 shared pathwaysNeutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Related via 2 shared pathways including Neutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. FCGR1A 2 shared pathwaysNeutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Related via 2 shared pathways including Neutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. ITGB2 2 shared pathwaysNeutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Related via 2 shared pathways including Neutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. C3 2 shared pathwaysNeutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Related via 2 shared pathways including Neutrophil extracellular trap formation, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
FCGR3A	0	[]	2	["Neutrophil extracellular trap formation","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"]	0	[]
ITGAL	0	[]	2	["Neutrophil extracellular trap formation","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"]	0	[]
FCGR1A	0	[]	2	["Neutrophil extracellular trap formation","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"]	0	[]
ITGB2	0	[]	2	["Neutrophil extracellular trap formation","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"]	0	[]
C3	0	[]	2	["Neutrophil extracellular trap formation","Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"]	0	[]

Diseases Linked via Similar Genes

Behcet disease Linked via 3 of 5 related genesFCGR3A, ITGAL, ITGB2 Diabetes mellitus type 2 Linked via 3 of 5 related genesITGAL, ITGB2, C3 Asthma Linked via 2 of 5 related genesFCGR3A, C3 Crohn disease Linked via 2 of 5 related genesFCGR3A, ITGAL Systemic lupus erythematosus Linked via 2 of 5 related genesFCGR3A, C3

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Behcet disease	3	["FCGR3A","ITGAL","ITGB2"]
Diabetes mellitus type 2	3	["ITGAL","ITGB2","C3"]
Asthma	2	["FCGR3A","C3"]
Crohn disease	2	["FCGR3A","ITGAL"]
Systemic lupus erythematosus	2	["FCGR3A","C3"]