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Gene Gene information from NCBI Gene database.
Entrez ID 7095
Gene name SEC62 preprotein translocation factor
Gene symbol SEC62
Synonyms (NCBI Gene)
Dtrp1HTP1TLOC1TP-1
Chromosome 3
Chromosome location 3q26.2
Summary The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated
miRNA miRNA information provided by mirtarbase database.
672 Show/Hide all (672)
miRTarBase ID miRNA Experiments Reference
MIRT005126 hsa-miR-30a-5p pSILAC 18668040
MIRT023739 hsa-miR-1-3p Proteomics 18668040
MIRT005126 hsa-miR-30a-5p Proteomics;Other 18668040
MIRT725161 hsa-miR-3168 HITS-CLIP 19536157
MIRT725160 hsa-miR-148b-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16 Show/Hide all (16)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 33961781, 37219487
GO:0005783 Component Endoplasmic reticulum IBA
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005783 Component Endoplasmic reticulum TAS 9020021
GO:0005789 Component Endoplasmic reticulum membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
602173 11846 ENSG00000008952
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q99442
Protein name Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1)
Protein function Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly position
PDB 7BRT
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03839 Sec62 87 → 308 Translocation protein Sec62 Family
Sequence
MAERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSK
WAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKE
EDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLD
GNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILL
LAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSE
TKKQQKSD
SEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNG
NDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS
Sequence length 399
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Protein export
Protein processing in endoplasmic reticulum