SACM1L (SAC1 like phosphatidylinositide phosphatase)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 22908 |
| Gene name | SAC1 like phosphatidylinositide phosphatase |
| Gene symbol | SACM1L |
| Synonyms (NCBI Gene) |
SAC1
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| Chromosome | 3 |
| Chromosome location | 3p21.31 |
| Summary | This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3 |
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miRNA
miRNA information provided by mirtarbase database.
555
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NTJ5 | ||||||||||
| Protein name | Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Suppressor of actin mutations 1-like protein) | ||||||||||
| Protein function | Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P) (PubMed:24209621, PubMed:27044890, PubMed:29461204, PubMed:30659099). Can also catalyze the hydrolysis of phosphatidylinositol 3-phospha | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in heart, brain, lung, liver, kidney, pancreas and testis. {ECO:0000269|PubMed:10048485}. | ||||||||||
| Sequence |
MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGI |
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| Sequence length | 587 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with SACM1L across shared curated disease and pathway associations.
5
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to SACM1L (see Related Genes above), that are NOT already directly curated for SACM1L itself -- a lead worth checking, not a confirmed association.
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