RPP30 (ribonuclease P/MRP subunit p30)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10556 |
| Gene name | Ribonuclease P/MRP subunit p30 |
| Gene symbol | RPP30 |
| Synonyms (NCBI Gene) |
TSG15
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| Chromosome | 10 |
| Chromosome location | 10q23.31 |
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miRNA
miRNA information provided by mirtarbase database.
353
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P78346 | ||||||||||
| Protein name | Ribonuclease P protein subunit p30 (RNaseP protein p30) (RNase P subunit 2) | ||||||||||
| Protein function | Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:30454648, PubMed:9037013, PubMed:9630247). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA s | ||||||||||
| PDB | 6AHR , 6AHU | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 268 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with RPP30 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to RPP30 (see Related Genes above), that are NOT already directly curated for RPP30 itself -- a lead worth checking, not a confirmed association.
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