PHOSPHO2 (phosphatase, orphan 2)

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Gene Gene information from NCBI Gene database.
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Entrez ID 493911
Gene name Phosphatase, orphan 2
Gene symbol PHOSPHO2
Synonyms (NCBI Gene)
-
Chromosome 2
Chromosome location 2q31.1
miRNA miRNA information provided by mirtarbase database.
1
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miRTarBase ID miRNA Experiments Reference
MIRT030418 hsa-miR-24-3p Microarray 19748357
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6 Show/Hide all (6)
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GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 32296183, 32814053
GO:0016787 Function Hydrolase activity IEA
GO:0016791 Function Phosphatase activity IBA
GO:0016791 Function Phosphatase activity IEA
GO:0033883 Function Pyridoxal phosphatase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TCD6
Protein name Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74)
Protein function Phosphatase that has high activity toward pyridoxal 5'-phosphate (PLP). Also active at much lower level toward pyrophosphate, phosphoethanolamine (PEA), phosphocholine (PCho), phospho-l-tyrosine, fructose-6-phosphate, p-nitrophenyl phosphate, an
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06888 Put_Phosphatase 3 → 239 Putative Phosphatase Family
Sequence
Sequence length 241
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
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KEGG Pathway
Vitamin B6 metabolism
Metabolic pathways
Biosynthesis of cofactors
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PDXP 2 shared pathwaysVitamin B6 metabolism, Biosynthesis of cofactors Related via 2 shared pathways including Vitamin B6 metabolism, Biosynthesis of cofactors. PNPO 2 shared pathwaysVitamin B6 metabolism, Biosynthesis of cofactors Related via 2 shared pathways including Vitamin B6 metabolism, Biosynthesis of cofactors. PDXK 2 shared pathwaysVitamin B6 metabolism, Biosynthesis of cofactors Related via 2 shared pathways including Vitamin B6 metabolism, Biosynthesis of cofactors. PSAT1 2 shared pathwaysVitamin B6 metabolism, Biosynthesis of cofactors Related via 2 shared pathways including Vitamin B6 metabolism, Biosynthesis of cofactors.
Schizophrenia Linked via 2 of 4 related genesPNPO, PSAT1 Status epilepticus Linked via 2 of 4 related genesPNPO, PDXK Distal hereditary motor neuropathy Linked via 1 of 4 related genesPNPO Pyridoxamine 5'-phosphate oxidase deficiency Linked via 1 of 4 related genesPNPO pyridoxal phosphate-responsive seizures Linked via 1 of 4 related genesPNPO