This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows
miRNAmiRNA information provided by mirtarbase database.
Gene ontology (GO)Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway) (PubMed:10924507). The NXF1-NXT1 heterodimer is involved in th
["Ribosome biogenesis in eukaryotes","Nucleocytoplasmic transport","mRNA surveillance pathway","Influenza A","Herpes simplex virus 1 infection","Transport of Mature mRNA derived from an Intron-Containing Transcript"]
["Ribosome biogenesis in eukaryotes","Nucleocytoplasmic transport","mRNA surveillance pathway","Influenza A","Herpes simplex virus 1 infection","Transport of Mature mRNA derived from an Intron-Containing Transcript"]
["Ribosome biogenesis in eukaryotes","Nucleocytoplasmic transport","mRNA surveillance pathway","Influenza A","Transport of Mature mRNA derived from an Intron-Containing Transcript"]
["Nucleocytoplasmic transport","mRNA surveillance pathway","Herpes simplex virus 1 infection","Transport of the SLBP independent Mature mRNA","Transport of the SLBP Dependant Mature mRNA","Transport of Mature mRNA Derived from an Intronless Transcript","Transport of Mature mRNA derived from an Intron-Containing Transcript"]
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Diseases Linked via Similar GenesDiseases curated for genes most similar to NXF1 (see Related Genes above), that are NOT already directly curated for NXF1 itself -- a lead worth checking, not a confirmed association.