MED24 (mediator complex subunit 24)

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Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 9862
• Gene name: Mediator complex subunit 24
• Gene symbol: MED24
• Synonyms (NCBI Gene): ARC100, CRSP100, CRSP4, DRIP100, MED5, THRAP4, TRAP100
• Chromosome: 17
• Chromosome location: 17q21.1
• Summary: This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activ

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs760297650	C>T	Likely-pathogenic	Coding sequence variant, missense variant, non coding transcript variant
rs1568162263	G>C	Likely-pathogenic	Missense variant, coding sequence variant, non coding transcript variant

miRNA Show/Hide all (433)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018060	hsa-miR-335-5p	Microarray	18185580
MIRT027655	hsa-miR-98-5p	Microarray	19088304
MIRT030488	hsa-miR-24-3p	Microarray	19748357
MIRT051295	hsa-miR-16-5p	CLASH	23622248
MIRT048129	hsa-miR-197-3p	CLASH	23622248
MIRT044508	hsa-miR-320a	CLASH	23622248
MIRT042865	hsa-miR-324-3p	CLASH	23622248
MIRT040976	hsa-miR-18a-3p	CLASH	23622248
MIRT039047	hsa-miR-766-3p	CLASH	23622248
MIRT610019	hsa-miR-8485	HITS-CLIP	22927820
MIRT610018	hsa-miR-329-3p	HITS-CLIP	22927820
MIRT610017	hsa-miR-362-3p	HITS-CLIP	22927820
MIRT610016	hsa-miR-603	HITS-CLIP	22927820
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	22927820
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	22927820
MIRT706194	hsa-miR-6508-5p	HITS-CLIP	22927820
MIRT706193	hsa-miR-8067	HITS-CLIP	22927820
MIRT610013	hsa-miR-3941	HITS-CLIP	22927820
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	22927820
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	22927820
MIRT610018	hsa-miR-329-3p	HITS-CLIP	22927820
MIRT610017	hsa-miR-362-3p	HITS-CLIP	22927820
MIRT610016	hsa-miR-603	HITS-CLIP	22927820
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	22927820
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	22927820
MIRT706194	hsa-miR-6508-5p	HITS-CLIP	22927820
MIRT706193	hsa-miR-8067	HITS-CLIP	22927820
MIRT610013	hsa-miR-3941	HITS-CLIP	22927820
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	22927820
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT610019	hsa-miR-8485	HITS-CLIP	23824327
MIRT610018	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT610017	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT610016	hsa-miR-603	HITS-CLIP	23824327
MIRT610015	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT610014	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT610013	hsa-miR-3941	HITS-CLIP	23824327
MIRT610012	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT1141440	hsa-miR-329	CLIP-seq
MIRT1141441	hsa-miR-520d-5p	CLIP-seq
MIRT1141442	hsa-miR-524-5p	CLIP-seq
MIRT1141443	hsa-miR-151-5p	CLIP-seq
MIRT1141444	hsa-miR-151b	CLIP-seq
MIRT1141445	hsa-miR-28-5p	CLIP-seq
MIRT1141446	hsa-miR-3139	CLIP-seq
MIRT1141440	hsa-miR-329	CLIP-seq
MIRT1141447	hsa-miR-4257	CLIP-seq
MIRT1141448	hsa-miR-4326	CLIP-seq
MIRT1141449	hsa-miR-4432	CLIP-seq
MIRT1141450	hsa-miR-4719	CLIP-seq
MIRT1141451	hsa-miR-499-5p	CLIP-seq
MIRT1141441	hsa-miR-520d-5p	CLIP-seq
MIRT1141442	hsa-miR-524-5p	CLIP-seq
MIRT1141452	hsa-miR-708	CLIP-seq
MIRT2040112	hsa-miR-1178	CLIP-seq
MIRT2040113	hsa-miR-1202	CLIP-seq
MIRT2040114	hsa-miR-125a-3p	CLIP-seq
MIRT2040115	hsa-miR-185	CLIP-seq
MIRT2040116	hsa-miR-3125	CLIP-seq
MIRT2040117	hsa-miR-3194-5p	CLIP-seq
MIRT1141440	hsa-miR-329	CLIP-seq
MIRT2040118	hsa-miR-3916	CLIP-seq
MIRT2040119	hsa-miR-3934	CLIP-seq
MIRT2040120	hsa-miR-3972	CLIP-seq
MIRT2040121	hsa-miR-4279	CLIP-seq
MIRT2040122	hsa-miR-4306	CLIP-seq
MIRT2040123	hsa-miR-4530	CLIP-seq
MIRT2040124	hsa-miR-4534	CLIP-seq
MIRT2040125	hsa-miR-4639-3p	CLIP-seq
MIRT2040126	hsa-miR-4644	CLIP-seq
MIRT2040127	hsa-miR-4645-5p	CLIP-seq
MIRT2040128	hsa-miR-4673	CLIP-seq
MIRT2040129	hsa-miR-764	CLIP-seq
MIRT2040130	hsa-miR-767-3p	CLIP-seq
MIRT2040131	hsa-miR-922	CLIP-seq
MIRT2040112	hsa-miR-1178	CLIP-seq
MIRT2040113	hsa-miR-1202	CLIP-seq
MIRT2269940	hsa-miR-1238	CLIP-seq
MIRT2040114	hsa-miR-125a-3p	CLIP-seq
MIRT2269941	hsa-miR-1294	CLIP-seq
MIRT2269942	hsa-miR-1343	CLIP-seq
MIRT1141443	hsa-miR-151-5p	CLIP-seq
MIRT1141444	hsa-miR-151b	CLIP-seq
MIRT2269943	hsa-miR-1587	CLIP-seq
MIRT2269944	hsa-miR-1827	CLIP-seq
MIRT2269945	hsa-miR-204	CLIP-seq
MIRT2269946	hsa-miR-211	CLIP-seq
MIRT2269947	hsa-miR-2115	CLIP-seq
MIRT2269948	hsa-miR-2467-5p	CLIP-seq
MIRT1141445	hsa-miR-28-5p	CLIP-seq
MIRT2269949	hsa-miR-3124-3p	CLIP-seq
MIRT1141446	hsa-miR-3139	CLIP-seq
MIRT2269950	hsa-miR-3180	CLIP-seq
MIRT2269951	hsa-miR-3180-3p	CLIP-seq
MIRT2040117	hsa-miR-3194-5p	CLIP-seq
MIRT2269952	hsa-miR-3196	CLIP-seq
MIRT1141440	hsa-miR-329	CLIP-seq
MIRT2269953	hsa-miR-3622a-5p	CLIP-seq
MIRT2269954	hsa-miR-3689d	CLIP-seq
MIRT2269955	hsa-miR-3690	CLIP-seq
MIRT2269956	hsa-miR-378g	CLIP-seq
MIRT2269957	hsa-miR-3927	CLIP-seq
MIRT2040119	hsa-miR-3934	CLIP-seq
MIRT2040120	hsa-miR-3972	CLIP-seq
MIRT2269958	hsa-miR-4254	CLIP-seq
MIRT1141447	hsa-miR-4257	CLIP-seq
MIRT2040121	hsa-miR-4279	CLIP-seq
MIRT2269959	hsa-miR-4316	CLIP-seq
MIRT1141448	hsa-miR-4326	CLIP-seq
MIRT1141449	hsa-miR-4432	CLIP-seq
MIRT2269960	hsa-miR-4433	CLIP-seq
MIRT2269961	hsa-miR-4446-5p	CLIP-seq
MIRT2269962	hsa-miR-4459	CLIP-seq
MIRT2269963	hsa-miR-4471	CLIP-seq
MIRT2269964	hsa-miR-4491	CLIP-seq
MIRT2269965	hsa-miR-4492	CLIP-seq
MIRT2269966	hsa-miR-4498	CLIP-seq
MIRT2269967	hsa-miR-4505	CLIP-seq
MIRT2040123	hsa-miR-4530	CLIP-seq
MIRT2040124	hsa-miR-4534	CLIP-seq
MIRT2040125	hsa-miR-4639-3p	CLIP-seq
MIRT2040127	hsa-miR-4645-5p	CLIP-seq
MIRT2269968	hsa-miR-4656	CLIP-seq
MIRT2269969	hsa-miR-4657	CLIP-seq
MIRT2040128	hsa-miR-4673	CLIP-seq
MIRT2269970	hsa-miR-4675	CLIP-seq
MIRT2269971	hsa-miR-4706	CLIP-seq
MIRT2269972	hsa-miR-4731-5p	CLIP-seq
MIRT2269973	hsa-miR-4741	CLIP-seq
MIRT2269974	hsa-miR-4749-5p	CLIP-seq
MIRT2269975	hsa-miR-4755-5p	CLIP-seq
MIRT2269976	hsa-miR-4764-5p	CLIP-seq
MIRT2269977	hsa-miR-4767	CLIP-seq
MIRT2269978	hsa-miR-4768-3p	CLIP-seq
MIRT2269979	hsa-miR-4781-5p	CLIP-seq
MIRT2269980	hsa-miR-4789-5p	CLIP-seq
MIRT1141451	hsa-miR-499-5p	CLIP-seq
MIRT2269981	hsa-miR-516a-3p	CLIP-seq
MIRT1141441	hsa-miR-520d-5p	CLIP-seq
MIRT1141442	hsa-miR-524-5p	CLIP-seq
MIRT2269982	hsa-miR-623	CLIP-seq
MIRT2269983	hsa-miR-642a	CLIP-seq
MIRT2269984	hsa-miR-671-5p	CLIP-seq
MIRT1141452	hsa-miR-708	CLIP-seq
MIRT2269985	hsa-miR-762	CLIP-seq
MIRT2040129	hsa-miR-764	CLIP-seq
MIRT2040130	hsa-miR-767-3p	CLIP-seq
MIRT2269986	hsa-miR-767-5p	CLIP-seq
MIRT2040131	hsa-miR-922	CLIP-seq
MIRT1141440	hsa-miR-329	CLIP-seq

Gene ontology (GO) Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0003712	Function	Transcription coregulator activity	IDA	10198638
GO:0003713	Function	Transcription coactivator activity	IDA	12218053
GO:0003713	Function	Transcription coactivator activity	NAS	10235266
GO:0005515	Function	Protein binding	IPI	24882805, 25792360, 33961781, 35271311
GO:0005634	Component	Nucleus	IDA	10235267, 24882805
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006366	Process	Transcription by RNA polymerase II	IEA
GO:0016592	Component	Mediator complex	IBA
GO:0016592	Component	Mediator complex	IEA
GO:0016592	Component	Mediator complex	NAS	9653119
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	NAS	11559591
GO:0035019	Process	Somatic stem cell population maintenance	IEA
GO:0042809	Function	Nuclear vitamin D receptor binding	NAS	10235266
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	10198638
GO:0046966	Function	Nuclear thyroid hormone receptor binding	IDA	10198638
GO:0051123	Process	RNA polymerase II preinitiation complex assembly	NAS	11559591
GO:0060261	Process	Positive regulation of transcription initiation by RNA polymerase II	IBA
GO:0060261	Process	Positive regulation of transcription initiation by RNA polymerase II	IDA	12218053
GO:0060261	Process	Positive regulation of transcription initiation by RNA polymerase II	NAS	11559591
GO:0070847	Component	Core mediator complex	IPI	24882805

Other IDs

• MIM: 607000
• HGNC: 22963
• e!Ensembl: ENSG00000008838

Protein

• UniProt ID: O75448
• Protein name: Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone recep
• Protein function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN
• PDB: 7EMF , 7ENA , 7ENC , 7ENJ , 7LBM , 8GXQ , 8GXS , 8T9D , 8TQW , 8TRH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF11277	Med24_N	1 → 987	Mediator complex subunit 24 N-terminal	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. Abundant in skeletal muscle, heart and placenta. {ECO:0000269|PubMed:9653119}.
• Sequence:

  MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
  LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
  CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
  AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
  FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
  EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
  NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
  LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
  ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
  NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
  SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
  ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
  KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
  LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
  EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
  LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
  MSSPKVVLAITDLSLPLGRQVAAKAIAAL

• Sequence length: 989

Pathways

KEGG Pathway	Reactome Pathway
Thyroid hormone signaling pathway	PPARA activates gene expression
	Generic Transcription Pathway
	Transcriptional regulation of white adipocyte differentiation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Short stature	Likely pathogenic	rs760297650, rs1568162263	RCV000736133 RCV000736132	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (13)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ASTHMA	—	GWAS catalog	31669095, 35126453	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	35126453	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHILDHOOD ONSET ASTHMA	—	GWAS catalog	31669095	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	—	GWAS catalog	33106845	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	37985818	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE MYELOMA	—	GWAS catalog	23502783	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROTIC DISORDER	—	GWAS catalog	29942085, 30595370, 32231276	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUTROPENIA	—	GWAS catalog	39024449	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	36810956	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	30541042	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC DUCTAL ADENOCARCINOMA	—	GWAS catalog	30541042	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (11)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Asthma	Asthma	GWASDB_DG	20860503		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Asthma	Asthma	Pubtator	22037903	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Asthma	Asthma	BEFREE	23452035, 27163155		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar disorder	Pubtator	40562893	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	31811111, 35069777	Associate	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	22037903	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	35044082	Associate	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	31248101		★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	GWASCAT_DG	23502783		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Multiple Myeloma	Multiple myeloma	GWASDB_DG	23502783		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neoplasms	Neoplasms	BEFREE	27179712		★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

ANXA13 2 shared diseasesPancreatic cancer, Multiple myeloma 2 shared evidence sourcesGWAS catalog (Pancreatic cancer), GWAS catalog (Multiple myeloma) Related via 2 shared diseases including Pancreatic cancer, Multiple myeloma — evidence mostly GWAS catalog. MED16 3 shared pathwaysThyroid hormone signaling pathway, PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 3 shared pathways including Thyroid hormone signaling pathway, PPARA activates gene expression. MED13L 3 shared pathwaysThyroid hormone signaling pathway, PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 3 shared pathways including Thyroid hormone signaling pathway, PPARA activates gene expression. MED4 3 shared pathwaysThyroid hormone signaling pathway, PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 3 shared pathways including Thyroid hormone signaling pathway, PPARA activates gene expression. MED30 3 shared pathwaysThyroid hormone signaling pathway, PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 3 shared pathways including Thyroid hormone signaling pathway, PPARA activates gene expression.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
ANXA13	2	["Pancreatic cancer","Multiple myeloma"]	0	[]	2	["GWAS catalog (Pancreatic cancer)","GWAS catalog (Multiple myeloma)"]
MED16	0	[]	3	["Thyroid hormone signaling pathway","PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
MED13L	0	[]	3	["Thyroid hormone signaling pathway","PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
MED4	0	[]	3	["Thyroid hormone signaling pathway","PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
MED30	0	[]	3	["Thyroid hormone signaling pathway","PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]

Diseases Linked via Similar Genes

Breast cancer Linked via 3 of 5 related genesANXA13, MED13L, MED30 Neurodevelopmental disorder Linked via 2 of 5 related genesMED16, MED13L Endometriosis Linked via 2 of 5 related genesMED16, MED4 Scoliosis Linked via 2 of 5 related genesMED13L, MED30 Estrogen-receptor negative breast cancer Linked via 1 of 5 related genesANXA13

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Breast cancer	3	["ANXA13","MED13L","MED30"]
Neurodevelopmental disorder	2	["MED16","MED13L"]
Endometriosis	2	["MED16","MED4"]
Scoliosis	2	["MED13L","MED30"]
Estrogen-receptor negative breast cancer	1	["ANXA13"]