LYPLA1 (lysophospholipase 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 10434
• Gene name: Lysophospholipase 1
• Gene symbol: LYPLA1
• Synonyms (NCBI Gene): APT-1, APT1, LPL-I, LPL1, hAPT1
• Chromosome: 8
• Chromosome location: 8q11.23
• Summary: This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate spli

miRNA Show/Hide all (434)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047071	hsa-miR-183-5p	CLASH	23622248
MIRT045770	hsa-miR-125a-5p	CLASH	23622248
MIRT437682	hsa-miR-222-3p	Microarray, qRT-PCR	22815788
MIRT641173	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT641172	hsa-miR-5688	HITS-CLIP	23824327
MIRT641170	hsa-miR-578	HITS-CLIP	23824327
MIRT647863	hsa-miR-4644	HITS-CLIP	23824327
MIRT663964	hsa-miR-193a-3p	HITS-CLIP	23824327
MIRT663963	hsa-miR-193b-3p	HITS-CLIP	23824327
MIRT663962	hsa-miR-892b	HITS-CLIP	23824327
MIRT647858	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647856	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT647855	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT647853	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647852	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT647851	hsa-miR-4435	HITS-CLIP	23824327
MIRT647849	hsa-miR-5096	HITS-CLIP	23824327
MIRT647850	hsa-miR-1303	HITS-CLIP	23824327
MIRT641173	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT641172	hsa-miR-5688	HITS-CLIP	23824327
MIRT641171	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT641170	hsa-miR-578	HITS-CLIP	23824327
MIRT647863	hsa-miR-4644	HITS-CLIP	23824327
MIRT647862	hsa-miR-3614-3p	HITS-CLIP	23824327
MIRT647861	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT647860	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT647859	hsa-miR-4297	HITS-CLIP	23824327
MIRT647857	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT647858	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647856	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT647855	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT647853	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647852	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT647851	hsa-miR-4435	HITS-CLIP	23824327
MIRT647849	hsa-miR-5096	HITS-CLIP	23824327
MIRT647850	hsa-miR-1303	HITS-CLIP	23824327
MIRT641173	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT641172	hsa-miR-5688	HITS-CLIP	23824327
MIRT641171	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT641170	hsa-miR-578	HITS-CLIP	23824327
MIRT641173	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT641172	hsa-miR-5688	HITS-CLIP	23824327
MIRT641170	hsa-miR-578	HITS-CLIP	23824327
MIRT647863	hsa-miR-4644	HITS-CLIP	23824327
MIRT663964	hsa-miR-193a-3p	HITS-CLIP	23824327
MIRT663963	hsa-miR-193b-3p	HITS-CLIP	23824327
MIRT663962	hsa-miR-892b	HITS-CLIP	23824327
MIRT647858	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647856	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT647855	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT647853	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647852	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT647851	hsa-miR-4435	HITS-CLIP	23824327
MIRT647849	hsa-miR-5096	HITS-CLIP	23824327
MIRT647850	hsa-miR-1303	HITS-CLIP	23824327
MIRT641173	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT641172	hsa-miR-5688	HITS-CLIP	23824327
MIRT641171	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT641170	hsa-miR-578	HITS-CLIP	23824327
MIRT647863	hsa-miR-4644	HITS-CLIP	23824327
MIRT647862	hsa-miR-3614-3p	HITS-CLIP	23824327
MIRT647861	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT647860	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT647859	hsa-miR-4297	HITS-CLIP	23824327
MIRT647857	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT647858	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647856	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT647855	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT647853	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT647854	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT647852	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT647851	hsa-miR-4435	HITS-CLIP	23824327
MIRT647849	hsa-miR-5096	HITS-CLIP	23824327
MIRT647850	hsa-miR-1303	HITS-CLIP	23824327
MIRT641173	hsa-miR-495-3p	HITS-CLIP	23824327
MIRT641172	hsa-miR-5688	HITS-CLIP	23824327
MIRT641171	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT641170	hsa-miR-578	HITS-CLIP	23824327
MIRT1123411	hsa-miR-101	CLIP-seq
MIRT1123412	hsa-miR-1244	CLIP-seq
MIRT1123413	hsa-miR-1245b-3p	CLIP-seq
MIRT1123414	hsa-miR-1285	CLIP-seq
MIRT1123415	hsa-miR-132	CLIP-seq
MIRT1123416	hsa-miR-139-5p	CLIP-seq
MIRT1123417	hsa-miR-141	CLIP-seq
MIRT1123418	hsa-miR-144	CLIP-seq
MIRT1123419	hsa-miR-186	CLIP-seq
MIRT1123420	hsa-miR-199a-3p	CLIP-seq
MIRT1123421	hsa-miR-199b-3p	CLIP-seq
MIRT1123422	hsa-miR-200a	CLIP-seq
MIRT1123423	hsa-miR-2116	CLIP-seq
MIRT1123424	hsa-miR-212	CLIP-seq
MIRT1123425	hsa-miR-2467-3p	CLIP-seq
MIRT1123426	hsa-miR-25	CLIP-seq
MIRT1123427	hsa-miR-3129-5p	CLIP-seq
MIRT1123428	hsa-miR-3133	CLIP-seq
MIRT1123429	hsa-miR-3153	CLIP-seq
MIRT1123430	hsa-miR-3187-5p	CLIP-seq
MIRT1123431	hsa-miR-32	CLIP-seq
MIRT1123432	hsa-miR-338-5p	CLIP-seq
MIRT1123433	hsa-miR-3613-3p	CLIP-seq
MIRT1123434	hsa-miR-3622b-5p	CLIP-seq
MIRT1123435	hsa-miR-363	CLIP-seq
MIRT1123436	hsa-miR-3647-3p	CLIP-seq
MIRT1123437	hsa-miR-3662	CLIP-seq
MIRT1123438	hsa-miR-367	CLIP-seq
MIRT1123439	hsa-miR-3671	CLIP-seq
MIRT1123440	hsa-miR-3678-3p	CLIP-seq
MIRT1123441	hsa-miR-3945	CLIP-seq
MIRT1123442	hsa-miR-4253	CLIP-seq
MIRT1123443	hsa-miR-4259	CLIP-seq
MIRT1123444	hsa-miR-4310	CLIP-seq
MIRT1123445	hsa-miR-4463	CLIP-seq
MIRT1123446	hsa-miR-450b-5p	CLIP-seq
MIRT1123447	hsa-miR-4642	CLIP-seq
MIRT1123448	hsa-miR-4645-3p	CLIP-seq
MIRT1123449	hsa-miR-4668-5p	CLIP-seq
MIRT1123450	hsa-miR-4677-5p	CLIP-seq
MIRT1123451	hsa-miR-4703-3p	CLIP-seq
MIRT1123452	hsa-miR-4709-3p	CLIP-seq
MIRT1123453	hsa-miR-4715-5p	CLIP-seq
MIRT1123454	hsa-miR-4735-5p	CLIP-seq
MIRT1123455	hsa-miR-4761-5p	CLIP-seq
MIRT1123456	hsa-miR-4796-5p	CLIP-seq
MIRT1123457	hsa-miR-518a-5p	CLIP-seq
MIRT1123458	hsa-miR-526b	CLIP-seq
MIRT1123459	hsa-miR-527	CLIP-seq
MIRT1123460	hsa-miR-548ag	CLIP-seq
MIRT1123461	hsa-miR-548ai	CLIP-seq
MIRT1123462	hsa-miR-548p	CLIP-seq
MIRT1123463	hsa-miR-607	CLIP-seq
MIRT1123464	hsa-miR-612	CLIP-seq
MIRT1123465	hsa-miR-626	CLIP-seq
MIRT1123466	hsa-miR-890	CLIP-seq
MIRT1123467	hsa-miR-92a	CLIP-seq
MIRT1123468	hsa-miR-92b	CLIP-seq
MIRT1123469	hsa-miR-944	CLIP-seq
MIRT2034857	hsa-miR-1207-3p	CLIP-seq
MIRT1123413	hsa-miR-1245b-3p	CLIP-seq
MIRT2034858	hsa-miR-133a	CLIP-seq
MIRT2034859	hsa-miR-133b	CLIP-seq
MIRT1123419	hsa-miR-186	CLIP-seq
MIRT2034860	hsa-miR-2052	CLIP-seq
MIRT2034861	hsa-miR-217	CLIP-seq
MIRT2034862	hsa-miR-3120-3p	CLIP-seq
MIRT1123428	hsa-miR-3133	CLIP-seq
MIRT2034863	hsa-miR-3143	CLIP-seq
MIRT2034864	hsa-miR-3145-3p	CLIP-seq
MIRT1123434	hsa-miR-3622b-5p	CLIP-seq
MIRT2034865	hsa-miR-3646	CLIP-seq
MIRT1123436	hsa-miR-3647-3p	CLIP-seq
MIRT1123437	hsa-miR-3662	CLIP-seq
MIRT2034866	hsa-miR-3973	CLIP-seq
MIRT2034867	hsa-miR-4517	CLIP-seq
MIRT1123449	hsa-miR-4668-5p	CLIP-seq
MIRT1123452	hsa-miR-4709-3p	CLIP-seq
MIRT1123454	hsa-miR-4735-5p	CLIP-seq
MIRT2034868	hsa-miR-4775	CLIP-seq
MIRT2034869	hsa-miR-520d-5p	CLIP-seq
MIRT2034870	hsa-miR-524-5p	CLIP-seq
MIRT2034871	hsa-miR-548a-5p	CLIP-seq
MIRT2034872	hsa-miR-548ab	CLIP-seq
MIRT2034873	hsa-miR-548ak	CLIP-seq
MIRT2034874	hsa-miR-548b-5p	CLIP-seq
MIRT2034875	hsa-miR-548c-5p	CLIP-seq
MIRT2034876	hsa-miR-548d-5p	CLIP-seq
MIRT2034877	hsa-miR-548h	CLIP-seq
MIRT2034878	hsa-miR-548i	CLIP-seq
MIRT2034879	hsa-miR-548j	CLIP-seq
MIRT2034880	hsa-miR-548w	CLIP-seq
MIRT2034881	hsa-miR-548y	CLIP-seq
MIRT2034882	hsa-miR-559	CLIP-seq
MIRT2034883	hsa-miR-586	CLIP-seq
MIRT2034884	hsa-miR-889	CLIP-seq
MIRT2034885	hsa-miR-922	CLIP-seq
MIRT1123469	hsa-miR-944	CLIP-seq
MIRT1123411	hsa-miR-101	CLIP-seq
MIRT2034857	hsa-miR-1207-3p	CLIP-seq
MIRT1123412	hsa-miR-1244	CLIP-seq
MIRT2265319	hsa-miR-1261	CLIP-seq
MIRT2265320	hsa-miR-130a	CLIP-seq
MIRT2265321	hsa-miR-130b	CLIP-seq
MIRT2265322	hsa-miR-1322	CLIP-seq
MIRT2034858	hsa-miR-133a	CLIP-seq
MIRT2034859	hsa-miR-133b	CLIP-seq
MIRT2265323	hsa-miR-135a	CLIP-seq
MIRT2265324	hsa-miR-135b	CLIP-seq
MIRT2265325	hsa-miR-138	CLIP-seq
MIRT1123416	hsa-miR-139-5p	CLIP-seq
MIRT1123417	hsa-miR-141	CLIP-seq
MIRT2265326	hsa-miR-142-5p	CLIP-seq
MIRT1123418	hsa-miR-144	CLIP-seq
MIRT1123419	hsa-miR-186	CLIP-seq
MIRT2265327	hsa-miR-1912	CLIP-seq
MIRT1123420	hsa-miR-199a-3p	CLIP-seq
MIRT1123421	hsa-miR-199b-3p	CLIP-seq
MIRT1123422	hsa-miR-200a	CLIP-seq
MIRT2034860	hsa-miR-2052	CLIP-seq
MIRT1123423	hsa-miR-2116	CLIP-seq
MIRT1123425	hsa-miR-2467-3p	CLIP-seq
MIRT1123426	hsa-miR-25	CLIP-seq
MIRT2265328	hsa-miR-301a	CLIP-seq
MIRT2265329	hsa-miR-301b	CLIP-seq
MIRT2034862	hsa-miR-3120-3p	CLIP-seq
MIRT1123427	hsa-miR-3129-5p	CLIP-seq
MIRT1123428	hsa-miR-3133	CLIP-seq
MIRT2034863	hsa-miR-3143	CLIP-seq
MIRT2034864	hsa-miR-3145-3p	CLIP-seq
MIRT2265330	hsa-miR-3156-5p	CLIP-seq
MIRT1123431	hsa-miR-32	CLIP-seq
MIRT1123432	hsa-miR-338-5p	CLIP-seq
MIRT2265331	hsa-miR-340	CLIP-seq
MIRT1123433	hsa-miR-3613-3p	CLIP-seq
MIRT1123434	hsa-miR-3622b-5p	CLIP-seq
MIRT1123435	hsa-miR-363	CLIP-seq
MIRT2034865	hsa-miR-3646	CLIP-seq
MIRT2265332	hsa-miR-3658	CLIP-seq
MIRT1123437	hsa-miR-3662	CLIP-seq
MIRT2265333	hsa-miR-3666	CLIP-seq
MIRT1123438	hsa-miR-367	CLIP-seq
MIRT1123440	hsa-miR-3678-3p	CLIP-seq
MIRT2265334	hsa-miR-3682-5p	CLIP-seq
MIRT1123442	hsa-miR-4253	CLIP-seq
MIRT1123443	hsa-miR-4259	CLIP-seq
MIRT2265335	hsa-miR-4281	CLIP-seq
MIRT2265336	hsa-miR-4295	CLIP-seq
MIRT2265337	hsa-miR-4477a	CLIP-seq
MIRT2265338	hsa-miR-4528	CLIP-seq
MIRT2265339	hsa-miR-454	CLIP-seq
MIRT1123448	hsa-miR-4645-3p	CLIP-seq
MIRT2265340	hsa-miR-4670-3p	CLIP-seq
MIRT2265341	hsa-miR-4671-3p	CLIP-seq
MIRT2265342	hsa-miR-4677-3p	CLIP-seq
MIRT1123450	hsa-miR-4677-5p	CLIP-seq
MIRT2265343	hsa-miR-4679	CLIP-seq
MIRT2265344	hsa-miR-4684-5p	CLIP-seq
MIRT1123451	hsa-miR-4703-3p	CLIP-seq
MIRT1123452	hsa-miR-4709-3p	CLIP-seq
MIRT1123453	hsa-miR-4715-5p	CLIP-seq
MIRT2265345	hsa-miR-4716-5p	CLIP-seq
MIRT2265346	hsa-miR-4729	CLIP-seq
MIRT1123455	hsa-miR-4761-5p	CLIP-seq
MIRT2265347	hsa-miR-4768-5p	CLIP-seq
MIRT2265348	hsa-miR-4793-5p	CLIP-seq
MIRT1123456	hsa-miR-4796-5p	CLIP-seq
MIRT2265349	hsa-miR-486-5p	CLIP-seq
MIRT2265350	hsa-miR-513a-3p	CLIP-seq
MIRT2265351	hsa-miR-539	CLIP-seq
MIRT1123460	hsa-miR-548ag	CLIP-seq
MIRT1123461	hsa-miR-548ai	CLIP-seq
MIRT2265352	hsa-miR-562	CLIP-seq
MIRT2265353	hsa-miR-580	CLIP-seq
MIRT2265354	hsa-miR-622	CLIP-seq
MIRT1123465	hsa-miR-626	CLIP-seq
MIRT1123466	hsa-miR-890	CLIP-seq
MIRT1123467	hsa-miR-92a	CLIP-seq
MIRT1123468	hsa-miR-92b	CLIP-seq
MIRT1123416	hsa-miR-139-5p	CLIP-seq
MIRT1123432	hsa-miR-338-5p	CLIP-seq
MIRT1123411	hsa-miR-101	CLIP-seq
MIRT2564360	hsa-miR-105	CLIP-seq
MIRT2564361	hsa-miR-1183	CLIP-seq
MIRT1123412	hsa-miR-1244	CLIP-seq
MIRT1123413	hsa-miR-1245b-3p	CLIP-seq
MIRT2564362	hsa-miR-1253	CLIP-seq
MIRT2564363	hsa-miR-1278	CLIP-seq
MIRT2564364	hsa-miR-1284	CLIP-seq
MIRT2564365	hsa-miR-1305	CLIP-seq
MIRT2265323	hsa-miR-135a	CLIP-seq
MIRT2265324	hsa-miR-135b	CLIP-seq
MIRT1123416	hsa-miR-139-5p	CLIP-seq
MIRT2564366	hsa-miR-140-3p	CLIP-seq
MIRT1123418	hsa-miR-144	CLIP-seq
MIRT2564367	hsa-miR-188-5p	CLIP-seq
MIRT1123420	hsa-miR-199a-3p	CLIP-seq
MIRT1123421	hsa-miR-199b-3p	CLIP-seq
MIRT2564368	hsa-miR-2054	CLIP-seq
MIRT2034861	hsa-miR-217	CLIP-seq
MIRT2564369	hsa-miR-219-5p	CLIP-seq
MIRT2564370	hsa-miR-224	CLIP-seq
MIRT1123427	hsa-miR-3129-5p	CLIP-seq
MIRT2034863	hsa-miR-3143	CLIP-seq
MIRT2564371	hsa-miR-3144-3p	CLIP-seq
MIRT2564372	hsa-miR-3177-5p	CLIP-seq
MIRT1123432	hsa-miR-338-5p	CLIP-seq
MIRT2564373	hsa-miR-346	CLIP-seq
MIRT2564374	hsa-miR-34a	CLIP-seq
MIRT2564375	hsa-miR-34c-5p	CLIP-seq
MIRT1123433	hsa-miR-3613-3p	CLIP-seq
MIRT2034865	hsa-miR-3646	CLIP-seq
MIRT1123436	hsa-miR-3647-3p	CLIP-seq
MIRT1123437	hsa-miR-3662	CLIP-seq
MIRT1123439	hsa-miR-3671	CLIP-seq
MIRT2564376	hsa-miR-3673	CLIP-seq
MIRT2564377	hsa-miR-374a	CLIP-seq
MIRT2564378	hsa-miR-374b	CLIP-seq
MIRT2564379	hsa-miR-380	CLIP-seq
MIRT2564380	hsa-miR-3924	CLIP-seq
MIRT2564381	hsa-miR-3940-5p	CLIP-seq
MIRT2034866	hsa-miR-3973	CLIP-seq
MIRT1123443	hsa-miR-4259	CLIP-seq
MIRT2564382	hsa-miR-4282	CLIP-seq
MIRT2564383	hsa-miR-4288	CLIP-seq
MIRT1123444	hsa-miR-4310	CLIP-seq
MIRT2564384	hsa-miR-4422	CLIP-seq
MIRT2564385	hsa-miR-4445	CLIP-seq
MIRT2265337	hsa-miR-4477a	CLIP-seq
MIRT2564386	hsa-miR-449a	CLIP-seq
MIRT2564387	hsa-miR-449b	CLIP-seq
MIRT2564388	hsa-miR-4503	CLIP-seq
MIRT2564389	hsa-miR-4507	CLIP-seq
MIRT2265338	hsa-miR-4528	CLIP-seq
MIRT1123451	hsa-miR-4703-3p	CLIP-seq
MIRT2564390	hsa-miR-4711-5p	CLIP-seq
MIRT2564391	hsa-miR-4712-3p	CLIP-seq
MIRT1123453	hsa-miR-4715-5p	CLIP-seq
MIRT2265346	hsa-miR-4729	CLIP-seq
MIRT1123454	hsa-miR-4735-5p	CLIP-seq
MIRT2564392	hsa-miR-4742-3p	CLIP-seq
MIRT2034868	hsa-miR-4775	CLIP-seq
MIRT2564393	hsa-miR-4782-3p	CLIP-seq
MIRT2265348	hsa-miR-4793-5p	CLIP-seq
MIRT2564394	hsa-miR-4795-3p	CLIP-seq
MIRT2265349	hsa-miR-486-5p	CLIP-seq
MIRT2564395	hsa-miR-508-3p	CLIP-seq
MIRT2034869	hsa-miR-520d-5p	CLIP-seq
MIRT2034870	hsa-miR-524-5p	CLIP-seq
MIRT2034871	hsa-miR-548a-5p	CLIP-seq
MIRT2034872	hsa-miR-548ab	CLIP-seq
MIRT2034873	hsa-miR-548ak	CLIP-seq
MIRT2034874	hsa-miR-548b-5p	CLIP-seq
MIRT2034875	hsa-miR-548c-5p	CLIP-seq
MIRT2034876	hsa-miR-548d-5p	CLIP-seq
MIRT2034877	hsa-miR-548h	CLIP-seq
MIRT2034878	hsa-miR-548i	CLIP-seq
MIRT2034879	hsa-miR-548j	CLIP-seq
MIRT1123462	hsa-miR-548p	CLIP-seq
MIRT2034880	hsa-miR-548w	CLIP-seq
MIRT2034881	hsa-miR-548y	CLIP-seq
MIRT2034882	hsa-miR-559	CLIP-seq
MIRT2564396	hsa-miR-587	CLIP-seq
MIRT2564397	hsa-miR-590-3p	CLIP-seq
MIRT2564398	hsa-miR-605	CLIP-seq
MIRT1123463	hsa-miR-607	CLIP-seq
MIRT2564399	hsa-miR-618	CLIP-seq
MIRT2564400	hsa-miR-619	CLIP-seq
MIRT2564401	hsa-miR-628-5p	CLIP-seq
MIRT2564402	hsa-miR-632	CLIP-seq
MIRT2564403	hsa-miR-654-3p	CLIP-seq
MIRT2564404	hsa-miR-767-3p	CLIP-seq
MIRT2564405	hsa-miR-875-5p	CLIP-seq
MIRT2564406	hsa-miR-885-5p	CLIP-seq
MIRT1123469	hsa-miR-944	CLIP-seq
MIRT1123411	hsa-miR-101	CLIP-seq
MIRT2564361	hsa-miR-1183	CLIP-seq
MIRT1123412	hsa-miR-1244	CLIP-seq
MIRT1123413	hsa-miR-1245b-3p	CLIP-seq
MIRT2564362	hsa-miR-1253	CLIP-seq
MIRT2564363	hsa-miR-1278	CLIP-seq
MIRT2564364	hsa-miR-1284	CLIP-seq
MIRT2564365	hsa-miR-1305	CLIP-seq
MIRT1123416	hsa-miR-139-5p	CLIP-seq
MIRT1123418	hsa-miR-144	CLIP-seq
MIRT2564367	hsa-miR-188-5p	CLIP-seq
MIRT1123420	hsa-miR-199a-3p	CLIP-seq
MIRT1123421	hsa-miR-199b-3p	CLIP-seq
MIRT2564368	hsa-miR-2054	CLIP-seq
MIRT2034861	hsa-miR-217	CLIP-seq
MIRT2564369	hsa-miR-219-5p	CLIP-seq
MIRT2564370	hsa-miR-224	CLIP-seq
MIRT1123427	hsa-miR-3129-5p	CLIP-seq
MIRT2564371	hsa-miR-3144-3p	CLIP-seq
MIRT2564372	hsa-miR-3177-5p	CLIP-seq
MIRT1123432	hsa-miR-338-5p	CLIP-seq
MIRT2564374	hsa-miR-34a	CLIP-seq
MIRT2564375	hsa-miR-34c-5p	CLIP-seq
MIRT1123433	hsa-miR-3613-3p	CLIP-seq
MIRT2034865	hsa-miR-3646	CLIP-seq
MIRT1123436	hsa-miR-3647-3p	CLIP-seq
MIRT1123439	hsa-miR-3671	CLIP-seq
MIRT2564376	hsa-miR-3673	CLIP-seq
MIRT2564379	hsa-miR-380	CLIP-seq
MIRT2034866	hsa-miR-3973	CLIP-seq
MIRT1123443	hsa-miR-4259	CLIP-seq
MIRT2564382	hsa-miR-4282	CLIP-seq
MIRT1123444	hsa-miR-4310	CLIP-seq
MIRT2564384	hsa-miR-4422	CLIP-seq
MIRT2564385	hsa-miR-4445	CLIP-seq
MIRT2564386	hsa-miR-449a	CLIP-seq
MIRT2564387	hsa-miR-449b	CLIP-seq
MIRT2564388	hsa-miR-4503	CLIP-seq
MIRT2265338	hsa-miR-4528	CLIP-seq
MIRT1123451	hsa-miR-4703-3p	CLIP-seq
MIRT2564391	hsa-miR-4712-3p	CLIP-seq
MIRT1123453	hsa-miR-4715-5p	CLIP-seq
MIRT2265346	hsa-miR-4729	CLIP-seq
MIRT1123454	hsa-miR-4735-5p	CLIP-seq
MIRT2564392	hsa-miR-4742-3p	CLIP-seq
MIRT2034868	hsa-miR-4775	CLIP-seq
MIRT2564393	hsa-miR-4782-3p	CLIP-seq
MIRT2564394	hsa-miR-4795-3p	CLIP-seq
MIRT2564395	hsa-miR-508-3p	CLIP-seq
MIRT2034869	hsa-miR-520d-5p	CLIP-seq
MIRT2034870	hsa-miR-524-5p	CLIP-seq
MIRT2034871	hsa-miR-548a-5p	CLIP-seq
MIRT2034872	hsa-miR-548ab	CLIP-seq
MIRT2034873	hsa-miR-548ak	CLIP-seq
MIRT2034874	hsa-miR-548b-5p	CLIP-seq
MIRT2034875	hsa-miR-548c-5p	CLIP-seq
MIRT2034876	hsa-miR-548d-5p	CLIP-seq
MIRT2034877	hsa-miR-548h	CLIP-seq
MIRT2034878	hsa-miR-548i	CLIP-seq
MIRT2034879	hsa-miR-548j	CLIP-seq
MIRT1123462	hsa-miR-548p	CLIP-seq
MIRT2034880	hsa-miR-548w	CLIP-seq
MIRT2034881	hsa-miR-548y	CLIP-seq
MIRT2034882	hsa-miR-559	CLIP-seq
MIRT2564396	hsa-miR-587	CLIP-seq
MIRT2564397	hsa-miR-590-3p	CLIP-seq
MIRT2564398	hsa-miR-605	CLIP-seq
MIRT1123463	hsa-miR-607	CLIP-seq
MIRT2564399	hsa-miR-618	CLIP-seq
MIRT2564401	hsa-miR-628-5p	CLIP-seq
MIRT2564404	hsa-miR-767-3p	CLIP-seq
MIRT2564405	hsa-miR-875-5p	CLIP-seq
MIRT2564406	hsa-miR-885-5p	CLIP-seq
MIRT1123469	hsa-miR-944	CLIP-seq

Gene ontology (GO) Show/Hide all (40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002084	Process	Protein depalmitoylation	IDA	19439193
GO:0002084	Process	Protein depalmitoylation	IMP	27481942
GO:0004620	Function	Phospholipase activity	IDA	21393252
GO:0004622	Function	Phosphatidylcholine lysophospholipase activity	IDA	19439193, 21393252
GO:0004622	Function	Phosphatidylcholine lysophospholipase activity	IEA
GO:0004622	Function	Phosphatidylcholine lysophospholipase activity	TAS	10064899
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	19439193
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	29362370
GO:0005783	Component	Endoplasmic reticulum	IDA	19439193
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	32958780
GO:0005886	Component	Plasma membrane	IDA	19439193
GO:0005886	Component	Plasma membrane	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0008474	Function	Palmitoyl-(protein) hydrolase activity	IBA
GO:0008474	Function	Palmitoyl-(protein) hydrolase activity	IDA	19439193, 32958780, 37802024
GO:0008474	Function	Palmitoyl-(protein) hydrolase activity	IEA
GO:0008474	Function	Palmitoyl-(protein) hydrolase activity	IMP	20418879
GO:0015908	Process	Fatty acid transport	IDA	32958780
GO:0016020	Component	Membrane	IEA
GO:0016298	Function	Lipase activity	IDA	24682756
GO:0016787	Function	Hydrolase activity	IEA
GO:0031965	Component	Nuclear membrane	IDA	19439193
GO:0031965	Component	Nuclear membrane	IEA
GO:0035973	Process	Aggrephagy	IDA	17580304
GO:0042997	Process	Negative regulation of Golgi to plasma membrane protein transport	IBA
GO:0042997	Process	Negative regulation of Golgi to plasma membrane protein transport	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0071211	Process	Protein targeting to vacuole involved in autophagy	IDA	37802024
GO:1905336	Process	Negative regulation of aggrephagy	IDA	37802024

Other IDs

• MIM: 605599
• HGNC: 6737
• e!Ensembl: ENSG00000120992

Protein

• UniProt ID: O75608
• Protein name: Acyl-protein thioesterase 1 (APT-1) (hAPT1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I) (Palmitoyl-protein hydrolase) (EC 3.1.2.22)
• Protein function: Acts as an acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Acts as a palmitoyl thioesterase that cata
• PDB: 1FJ2 , 5SYM , 6QGN , 6QGO , 6QGQ , 6QGS
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02230	Abhydrolase_2	8 → 226	Phospholipase/Carboxylesterase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Platelets. {ECO:0000269|PubMed:21393252}.
• Sequence:

  MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRP
  VTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQ
  GGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLM
  FGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID

• Sequence length: 230

Pathways

KEGG Pathway	Reactome Pathway
Glycerophospholipid metabolism	eNOS activation
Choline metabolism in cancer

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Lung cancer	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (16)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Arteriosclerosis	Arteriosclerosis	BEFREE	12032161		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	12032161		★☆☆☆☆ Found in Text Mining only
Autoimmune Lymphoproliferative Syndrome	Autoimmune Lymphoproliferative Disorder	BEFREE	10090885		★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	28224267		★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	12032161		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	12032161		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	29374012		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28224267, 29648538		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	25944911, 26771141, 29648538	Associate	★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	28614908, 29648538		★☆☆☆☆ Found in Text Mining only
Metastatic melanoma	Metastatic Melanoma	BEFREE	29648538		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29648538, 30431103		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	30431103		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	BEFREE	28614908		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	11568974		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	40193710	Stimulate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

GPCPD1 2 shared pathwaysGlycerophospholipid metabolism, Choline metabolism in cancer Related via 2 shared pathways including Glycerophospholipid metabolism, Choline metabolism in cancer. CHKA 2 shared pathwaysGlycerophospholipid metabolism, Choline metabolism in cancer Related via 2 shared pathways including Glycerophospholipid metabolism, Choline metabolism in cancer. CHKB 2 shared pathwaysGlycerophospholipid metabolism, Choline metabolism in cancer Related via 2 shared pathways including Glycerophospholipid metabolism, Choline metabolism in cancer. PCYT1A 2 shared pathwaysGlycerophospholipid metabolism, Choline metabolism in cancer Related via 2 shared pathways including Glycerophospholipid metabolism, Choline metabolism in cancer. PCYT1B 2 shared pathwaysGlycerophospholipid metabolism, Choline metabolism in cancer Related via 2 shared pathways including Glycerophospholipid metabolism, Choline metabolism in cancer.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
GPCPD1	0	[]	2	["Glycerophospholipid metabolism","Choline metabolism in cancer"]	0	[]
CHKA	0	[]	2	["Glycerophospholipid metabolism","Choline metabolism in cancer"]	0	[]
CHKB	0	[]	2	["Glycerophospholipid metabolism","Choline metabolism in cancer"]	0	[]
PCYT1A	0	[]	2	["Glycerophospholipid metabolism","Choline metabolism in cancer"]	0	[]
PCYT1B	0	[]	2	["Glycerophospholipid metabolism","Choline metabolism in cancer"]	0	[]

Diseases Linked via Similar Genes

Glomerulonephritis Linked via 1 of 5 related genesGPCPD1 Nonsyndromic intellectual disability Linked via 1 of 5 related genesCHKA Color vision deficiency Linked via 1 of 5 related genesCHKA Neurodevelopmental disorder Linked via 1 of 5 related genesCHKA Intellectual disability Linked via 1 of 5 related genesCHKA

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Glomerulonephritis	1	["GPCPD1"]
Nonsyndromic intellectual disability	1	["CHKA"]
Color vision deficiency	1	["CHKA"]
Neurodevelopmental disorder	1	["CHKA"]
Intellectual disability	1	["CHKA"]