LILRA2 (leukocyte immunoglobulin like receptor A2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 11027 |
| Gene name | Leukocyte immunoglobulin like receptor A2 |
| Gene symbol | LILRA2 |
| Synonyms (NCBI Gene) |
CD85HILT1LIR-7LIR7
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| Chromosome | 19 |
| Chromosome location | 19q13.42 |
| Summary | This gene encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The encoded protein is an activating receptor that inhibits dendritic cel |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8N149 | |||||||||||||||
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 2 (CD85 antigen-like family member H) (Immunoglobulin-like transcript 1) (ILT-1) (Leukocyte immunoglobulin-like receptor 7) (LIR-7) (CD antigen CD85h) | |||||||||||||||
| Protein function | Part of the innate immune responses against microbial infection (PubMed:12529506, PubMed:27572839). Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic ba | |||||||||||||||
| PDB | 2OTP | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected on the surface of all peripheral blood monocytes, neutrophils, basophils and eosinophils (at protein level) (PubMed:12529506, PubMed:22479404). Expression levels are very low or not detectable on monocytes, T-cells, B-cells, d | |||||||||||||||
| Sequence |
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| Sequence length | 483 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with LILRA2 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to LILRA2 (see Related Genes above), that are NOT already directly curated for LILRA2 itself -- a lead worth checking, not a confirmed association.
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