Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	8687
Gene name	Keratin 38
Gene symbol	KRT38
Synonyms (NCBI Gene)	HA8KRTHA8hHa8
Chromosome	17
Chromosome location	17q21.2
Summary	The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017514	hsa-miR-335-5p	Microarray	18185580
MIRT1101302	hsa-miR-1252	CLIP-seq
MIRT1101303	hsa-miR-2278	CLIP-seq
MIRT1101304	hsa-miR-3123	CLIP-seq
MIRT1101305	hsa-miR-3920	CLIP-seq
MIRT1101306	hsa-miR-3925-5p	CLIP-seq
MIRT1101307	hsa-miR-3976	CLIP-seq
MIRT1101308	hsa-miR-4287	CLIP-seq
MIRT1101309	hsa-miR-4311	CLIP-seq
MIRT1101310	hsa-miR-4446-5p	CLIP-seq
MIRT1101311	hsa-miR-4469	CLIP-seq
MIRT1101312	hsa-miR-4685-3p	CLIP-seq
MIRT1101313	hsa-miR-4755-5p	CLIP-seq
MIRT1101314	hsa-miR-4762-3p	CLIP-seq
MIRT1101315	hsa-miR-513a-3p	CLIP-seq
MIRT1101316	hsa-miR-539	CLIP-seq
MIRT1101317	hsa-miR-642a	CLIP-seq
MIRT2027574	hsa-miR-3927	CLIP-seq
MIRT2027575	hsa-miR-4451	CLIP-seq
MIRT2258872	hsa-miR-1185	CLIP-seq
MIRT2258873	hsa-miR-1827	CLIP-seq
MIRT2258874	hsa-miR-23a	CLIP-seq
MIRT2258875	hsa-miR-23b	CLIP-seq
MIRT2258876	hsa-miR-23c	CLIP-seq
MIRT2258877	hsa-miR-3154	CLIP-seq
MIRT2258878	hsa-miR-3612	CLIP-seq
MIRT2258879	hsa-miR-3679-5p	CLIP-seq
MIRT2258880	hsa-miR-4434	CLIP-seq
MIRT2258881	hsa-miR-4459	CLIP-seq
MIRT2258882	hsa-miR-4516	CLIP-seq
MIRT2258883	hsa-miR-451b	CLIP-seq
MIRT2258884	hsa-miR-4722-5p	CLIP-seq
MIRT2258885	hsa-miR-4766-5p	CLIP-seq
MIRT2258886	hsa-miR-650	CLIP-seq
MIRT2258887	hsa-miR-940	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0002009	Process	Morphogenesis of an epithelium	IBA
GO:0005198	Function	Structural molecule activity	IEA
GO:0005198	Function	Structural molecule activity	TAS	9756910
GO:0005515	Function	Protein binding	IPI	25416956, 25910212, 26871637, 29892012, 31515488, 32296183, 33961781
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IBA
GO:0005882	Component	Intermediate filament	IEA
GO:0030280	Function	Structural constituent of skin epidermis	IBA
GO:0030855	Process	Epithelial cell differentiation	IBA
GO:0045095	Component	Keratin filament	IBA
GO:0045109	Process	Intermediate filament organization	IBA
GO:0070062	Component	Extracellular exosome	HDA	23533145

MIM	HGNC	e!Ensembl
604542	6456	ENSG00000171360

O76015

Protein name

Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8) (Keratin-38) (K38)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00038	Filament	103 → 414	Intermediate filament protein	Coiled-coil

Sequence

MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST
PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE
KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID
NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS
NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE
GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA
QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC
STSPSCVTAPCAPRPSCGPCTTCGPTCGASTTGSRF

Sequence length

456

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Estrogen signaling pathway	Keratinization
Staphylococcus aureus infection	Formation of the cornified envelope

KRT38 (keratin 38)

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