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Gene Gene information from NCBI Gene database.
Entrez ID 57461
Gene name ISY1 spliceosome associated protein
Gene symbol ISY1
Synonyms (NCBI Gene)
FSAP33
Chromosome 3
Chromosome location 3q21.3
miRNA miRNA information provided by mirtarbase database.
385 Show/Hide all (385)
miRTarBase ID miRNA Experiments Reference
MIRT039403 hsa-miR-421 CLASH 23622248
MIRT721712 hsa-miR-4797-5p HITS-CLIP 19536157
MIRT721711 hsa-miR-1302 HITS-CLIP 19536157
MIRT721710 hsa-miR-4298 HITS-CLIP 19536157
MIRT721709 hsa-miR-450a-1-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19 Show/Hide all (19)
GO ID Ontology Definition Evidence Reference
GO:0000350 Process Generation of catalytic spliceosome for second transesterification step IBA
GO:0000350 Process Generation of catalytic spliceosome for second transesterification step IEA
GO:0000389 Process MRNA 3'-splice site recognition IBA
GO:0000398 Process MRNA splicing, via spliceosome IC 11991638
GO:0000398 Process MRNA splicing, via spliceosome IDA 29301961
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612764 29201 ENSG00000240682
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Spliceosome Formation of TC-NER Pre-Incision Complex
  Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  Dual incision in TC-NER
  Gap-filling DNA repair synthesis and ligation in TC-NER
  mRNA Splicing - Major Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations