Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	50865
Gene name	Heme binding protein 1
Gene symbol	HEBP1
Synonyms (NCBI Gene)	HBPHEBP
Chromosome	12
Chromosome location	12p13.1
Summary	The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor

97 Show/Hide all (97)

miRTarBase ID	miRNA	Experiments
MIRT1043326	hsa-miR-1252	CLIP-seq
MIRT1043327	hsa-miR-1269	CLIP-seq
MIRT1043328	hsa-miR-1269b	CLIP-seq
MIRT1043329	hsa-miR-1301	CLIP-seq
MIRT1043330	hsa-miR-145	CLIP-seq
MIRT1043331	hsa-miR-382	CLIP-seq
MIRT1043332	hsa-miR-4428	CLIP-seq
MIRT1043333	hsa-miR-4476	CLIP-seq
MIRT1043334	hsa-miR-4529-3p	CLIP-seq
MIRT1043335	hsa-miR-4533	CLIP-seq
MIRT1043336	hsa-miR-4640-3p	CLIP-seq
MIRT1043337	hsa-miR-4660	CLIP-seq
MIRT1043338	hsa-miR-4667-3p	CLIP-seq
MIRT1043339	hsa-miR-4712-5p	CLIP-seq
MIRT1043340	hsa-miR-4747-5p	CLIP-seq
MIRT1043341	hsa-miR-5047	CLIP-seq
MIRT1043342	hsa-miR-770-5p	CLIP-seq
MIRT2009272	hsa-miR-1290	CLIP-seq
MIRT2009273	hsa-miR-22	CLIP-seq
MIRT2009274	hsa-miR-320a	CLIP-seq
MIRT2009275	hsa-miR-320b	CLIP-seq
MIRT2009276	hsa-miR-320c	CLIP-seq
MIRT2009277	hsa-miR-320d	CLIP-seq
MIRT2009278	hsa-miR-3663-5p	CLIP-seq
MIRT2009279	hsa-miR-4429	CLIP-seq
MIRT2009280	hsa-miR-4434	CLIP-seq
MIRT2009281	hsa-miR-4516	CLIP-seq
MIRT2009282	hsa-miR-4531	CLIP-seq
MIRT2009283	hsa-miR-4755-3p	CLIP-seq
MIRT2009284	hsa-miR-601	CLIP-seq
MIRT2241701	hsa-miR-1207-3p	CLIP-seq
MIRT2241702	hsa-miR-224	CLIP-seq
MIRT2241703	hsa-miR-23a	CLIP-seq
MIRT2241704	hsa-miR-23b	CLIP-seq
MIRT2241705	hsa-miR-23c	CLIP-seq
MIRT2241706	hsa-miR-4269	CLIP-seq
MIRT1043332	hsa-miR-4428	CLIP-seq
MIRT1043333	hsa-miR-4476	CLIP-seq
MIRT2241707	hsa-miR-4514	CLIP-seq
MIRT1043335	hsa-miR-4533	CLIP-seq
MIRT1043336	hsa-miR-4640-3p	CLIP-seq
MIRT1043338	hsa-miR-4667-3p	CLIP-seq
MIRT2241708	hsa-miR-4692	CLIP-seq
MIRT2241709	hsa-miR-4719	CLIP-seq
MIRT2241710	hsa-miR-4742-5p	CLIP-seq
MIRT2241711	hsa-miR-4772-5p	CLIP-seq
MIRT2241701	hsa-miR-1207-3p	CLIP-seq
MIRT1043326	hsa-miR-1252	CLIP-seq
MIRT1043327	hsa-miR-1269	CLIP-seq
MIRT1043328	hsa-miR-1269b	CLIP-seq
MIRT1043329	hsa-miR-1301	CLIP-seq
MIRT1043330	hsa-miR-145	CLIP-seq
MIRT1043331	hsa-miR-382	CLIP-seq
MIRT1043332	hsa-miR-4428	CLIP-seq
MIRT1043333	hsa-miR-4476	CLIP-seq
MIRT1043334	hsa-miR-4529-3p	CLIP-seq
MIRT1043335	hsa-miR-4533	CLIP-seq
MIRT1043336	hsa-miR-4640-3p	CLIP-seq
MIRT1043337	hsa-miR-4660	CLIP-seq
MIRT1043338	hsa-miR-4667-3p	CLIP-seq
MIRT1043339	hsa-miR-4712-5p	CLIP-seq
MIRT1043340	hsa-miR-4747-5p	CLIP-seq
MIRT1043341	hsa-miR-5047	CLIP-seq
MIRT1043342	hsa-miR-770-5p	CLIP-seq
MIRT2241701	hsa-miR-1207-3p	CLIP-seq
MIRT1043326	hsa-miR-1252	CLIP-seq
MIRT2682246	hsa-miR-1254	CLIP-seq
MIRT1043327	hsa-miR-1269	CLIP-seq
MIRT1043328	hsa-miR-1269b	CLIP-seq
MIRT2009272	hsa-miR-1290	CLIP-seq
MIRT1043329	hsa-miR-1301	CLIP-seq
MIRT2682247	hsa-miR-1912	CLIP-seq
MIRT2009273	hsa-miR-22	CLIP-seq
MIRT2682248	hsa-miR-3116	CLIP-seq
MIRT2009274	hsa-miR-320a	CLIP-seq
MIRT2009275	hsa-miR-320b	CLIP-seq
MIRT2009276	hsa-miR-320c	CLIP-seq
MIRT2009277	hsa-miR-320d	CLIP-seq
MIRT2009278	hsa-miR-3663-5p	CLIP-seq
MIRT1043331	hsa-miR-382	CLIP-seq
MIRT2682249	hsa-miR-4254	CLIP-seq
MIRT1043332	hsa-miR-4428	CLIP-seq
MIRT2009279	hsa-miR-4429	CLIP-seq
MIRT2009280	hsa-miR-4434	CLIP-seq
MIRT1043333	hsa-miR-4476	CLIP-seq
MIRT2009281	hsa-miR-4516	CLIP-seq
MIRT1043334	hsa-miR-4529-3p	CLIP-seq
MIRT2009282	hsa-miR-4531	CLIP-seq
MIRT1043335	hsa-miR-4533	CLIP-seq
MIRT1043336	hsa-miR-4640-3p	CLIP-seq
MIRT1043337	hsa-miR-4660	CLIP-seq
MIRT1043338	hsa-miR-4667-3p	CLIP-seq
MIRT1043340	hsa-miR-4747-5p	CLIP-seq
MIRT2009283	hsa-miR-4755-3p	CLIP-seq
MIRT1043341	hsa-miR-5047	CLIP-seq
MIRT2009284	hsa-miR-601	CLIP-seq
MIRT2682250	hsa-miR-661	CLIP-seq

7 Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0007623	Process	Circadian rhythm	TAS	10640688
GO:0020037	Function	Heme binding	IBA
GO:0020037	Function	Heme binding	ISS
GO:0070062	Component	Extracellular exosome	HDA	19056867

MIM	HGNC	e!Ensembl
605826	17176	ENSG00000013583

Q9NRV9

Protein name

Heme-binding protein 1 (p22HBP)

Protein function

May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-met

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04832	SOUL	13 → 187	SOUL heme-binding protein	Family

Sequence

MLGMIKNSLFGSVETWPWQVLSKGDKEEVAYEERACEGGKFATVEVTDKPVDEALREAMP
KVAKYAGGTNDKGIGMGMTVPISFAVFPNEDGSLQKKLKVWFRIPNQFQSDPPAPSDKSV
KIEEREGITVYSMQFGGYAKEADYVAQATRLRAALEGTATYRGDIYFCTGYDPPMKPYGR
RNEIWLLKT

Sequence length

189

Interactions

View interactions

Reactome Pathway
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands

HEBP1 (heme binding protein 1)

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