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Gene Gene information from NCBI Gene database.
Entrez ID 23710
Gene name GABA type A receptor associated protein like 1
Gene symbol GABARAPL1
Synonyms (NCBI Gene)
APG8-LIKEAPG8LATG8ATG8BATG8LGEC1
Chromosome 12
Chromosome location 12p13.2
miRNA miRNA information provided by mirtarbase database.
752 Show/Hide all (752)
miRTarBase ID miRNA Experiments Reference
MIRT016044 hsa-miR-374b-5p Sequencing 20371350
MIRT017763 hsa-miR-335-5p Microarray 18185580
MIRT020789 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT027090 hsa-miR-103a-3p Sequencing 20371350
MIRT031653 hsa-miR-16-5p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
35 Show/Hide all (35)
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA
GO:0000421 Component Autophagosome membrane IBA
GO:0000421 Component Autophagosome membrane TAS
GO:0000423 Process Mitophagy IBA
GO:0005515 Function Protein binding IPI 9892355, 16189514, 16431922, 17580304, 19250911, 20010802, 20200478, 20562859, 20810658, 21516116, 21617041, 21893048, 22354992, 22470510, 22948227, 24668264, 25416956, 25684205, 26040720, 26347139, 28514442, 29892012, 31515488, 32296183, 32315611, 33961781, 34524948, 35271311, 3721
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607420 4068 ENSG00000139112
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H0R8
Protein name Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Protein function Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor (PubMed:16431922). Involved in formation of autophagosomal vacuoles (PubMed:2
PDB 2L8J , 2R2Q , 5DPT , 5LXH , 5LXI , 6HOI , 6HOL , 6YOO , 7AA7 , 7AA9 , 7JHX , 8X8A
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02991 Atg8 13 → 116 Autophagy protein Atg8 ubiquitin like Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particular
Sequence
Sequence length 117
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
FoxO signaling pathway Macroautophagy
Autophagy - other  
Mitophagy - animal  
Autophagy - animal  
NOD-like receptor signaling pathway  
GABAergic synapse