Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	2527
Gene name	Fucosyltransferase 5
Gene symbol	FUT5
Synonyms (NCBI Gene)	FUC-TV
Chromosome	19
Chromosome location	19p13.3

15 Show/Hide all (15)

miRTarBase ID	miRNA	Experiments
MIRT1006738	hsa-miR-3120-3p	CLIP-seq
MIRT1006739	hsa-miR-3130-3p	CLIP-seq
MIRT1006740	hsa-miR-3942-5p	CLIP-seq
MIRT1006741	hsa-miR-4703-5p	CLIP-seq
MIRT1006742	hsa-miR-548aa	CLIP-seq
MIRT1006743	hsa-miR-596	CLIP-seq
MIRT1006744	hsa-miR-767-5p	CLIP-seq
MIRT1006745	hsa-miR-876-3p	CLIP-seq
MIRT2388256	hsa-miR-1909	CLIP-seq
MIRT2388257	hsa-miR-214	CLIP-seq
MIRT2388258	hsa-miR-2355-5p	CLIP-seq
MIRT2388259	hsa-miR-2467-5p	CLIP-seq
MIRT2388260	hsa-miR-3619-5p	CLIP-seq
MIRT2388261	hsa-miR-4530	CLIP-seq
MIRT2388262	hsa-miR-761	CLIP-seq

30 Show/Hide all (30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	TAS	11698403
GO:0005975	Process	Carbohydrate metabolic process	TAS	1339443
GO:0006486	Process	Protein glycosylation	IEA
GO:0006486	Process	Protein glycosylation	TAS	11698403
GO:0006487	Process	Protein N-linked glycosylation	IDA	29593094
GO:0006493	Process	Protein O-linked glycosylation	IDA	29593094
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006665	Process	Sphingolipid metabolic process	IEA
GO:0006672	Process	Ceramide metabolic process	IDA	7721776, 9737988, 17604274
GO:0008417	Function	Fucosyltransferase activity	IDA	7721776, 17604274
GO:0008417	Function	Fucosyltransferase activity	IEA
GO:0008417	Function	Fucosyltransferase activity	TAS	1339443
GO:0009311	Process	Oligosaccharide metabolic process	IDA	1740457, 9737988
GO:0009312	Process	Oligosaccharide biosynthetic process	IEA
GO:0009312	Process	Oligosaccharide biosynthetic process	TAS
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0017060	Function	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	IDA	1740457, 9737988, 14718375
GO:0017060	Function	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	IEA
GO:0017083	Function	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IDA	1740457, 7721776, 9737988, 14718375, 17604274, 29593094
GO:0017083	Function	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IEA
GO:0032580	Component	Golgi cisterna membrane	IEA
GO:0036065	Process	Fucosylation	IBA
GO:0042355	Process	L-fucose catabolic process	NAS	11698403
GO:0046920	Function	Alpha-(1->3)-fucosyltransferase activity	IBA
GO:0046920	Function	Alpha-(1->3)-fucosyltransferase activity	TAS	11698403

MIM	HGNC	e!Ensembl
136835	4016	ENSG00000130383

Q11128

Protein name

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucos

Protein function

Catalyzes preferentially the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl-beta-D-glucosamine (GlcNAc) of an N-acetyllactosamine unit (type 2 chain) of an oligosaccharide, or a glycoprotein- and a glycolipid-l

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00852	Glyco_transf_10	202 → 373	Glycosyltransferase family 10 (fucosyltransferase) C-term	Family
PF17039	Glyco_tran_10_N	73 → 183	Fucosyltransferase, N-terminal	Domain

Tissue specificity

TISSUE SPECIFICITY: Liver, colon and testis and trace amounts in T-cells and brain.

Sequence

MDPLGPAKPQWLWRRCLAGLLFQLLVAVCFFSYLRVSRDDATGSPRPGLMAVEPVTGAPN
GSRCQDSMATPAHPTLLILLWTWPFNTPVALPRCSEMVPGAADCNITADSSVYPQADAVI
VHHWDIMYNPSANLPPPTRPQGQRWIWFSMESPSNCRHLEALDGYFNLTMSYRSDSDIFT
PYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWKPDSARVRYYQSLQAHLKVDVYGRSHK
PLPKGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPP
DAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQQE
SRYQTVRSIAAWFT

Sequence length

374

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Glycosphingolipid biosynthesis - lacto and neolacto series	Lewis blood group biosynthesis
Metabolic pathways

FUT5 (fucosyltransferase 5)

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