FCF1 (FCF1 rRNA-processing protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51077 |
| Gene name | FCF1 rRNA-processing protein |
| Gene symbol | FCF1 |
| Synonyms (NCBI Gene) |
BkaC14orf111CGI-35UTP24
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| Chromosome | 14 |
| Chromosome location | 14q24.3 |
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miRNA
miRNA information provided by mirtarbase database.
540
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y324 | ||||||||||
| Protein name | rRNA-processing protein FCF1 homolog | ||||||||||
| Protein function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associat | ||||||||||
| PDB | 7MQ8 , 7MQ9 , 7MQA | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MGKQKKTRKYATMKRMLSLRDQRLKEKDRLKPKKKEKKDPSALKEREVPQHPSCLFFQYN |
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| Sequence length | 198 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with FCF1 across shared curated disease and pathway associations.
5
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to FCF1 (see Related Genes above), that are NOT already directly curated for FCF1 itself -- a lead worth checking, not a confirmed association.
5
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