Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	253314
Gene name	Eukaryotic translation initiation factor 4E family member 1B
Gene symbol	EIF4E1B
Synonyms (NCBI Gene)	-
Chromosome	5
Chromosome location	5q35.2

22 Show/Hide all (22)

miRTarBase ID	miRNA	Experiments
MIRT958093	hsa-miR-1224-5p	CLIP-seq
MIRT958094	hsa-miR-3614-5p	CLIP-seq
MIRT958095	hsa-miR-3915	CLIP-seq
MIRT958096	hsa-miR-4316	CLIP-seq
MIRT958097	hsa-miR-4436a	CLIP-seq
MIRT958098	hsa-miR-4436b-5p	CLIP-seq
MIRT958099	hsa-miR-4494	CLIP-seq
MIRT958100	hsa-miR-4689	CLIP-seq
MIRT958101	hsa-miR-4710	CLIP-seq
MIRT958102	hsa-miR-4751	CLIP-seq
MIRT958103	hsa-miR-4792	CLIP-seq
MIRT958104	hsa-miR-4795-3p	CLIP-seq
MIRT958105	hsa-miR-499a-5p	CLIP-seq
MIRT1983790	hsa-miR-1207-3p	CLIP-seq
MIRT2219068	hsa-miR-1293	CLIP-seq
MIRT2219069	hsa-miR-1343	CLIP-seq
MIRT2219070	hsa-miR-3667-3p	CLIP-seq
MIRT2219071	hsa-miR-4261	CLIP-seq
MIRT958096	hsa-miR-4316	CLIP-seq
MIRT2219072	hsa-miR-4483	CLIP-seq
MIRT958101	hsa-miR-4710	CLIP-seq
MIRT958103	hsa-miR-4792	CLIP-seq

11 Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000340	Function	RNA 7-methylguanosine cap binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0003743	Function	Translation initiation factor activity	IBA
GO:0003743	Function	Translation initiation factor activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005737	Component	Cytoplasm	IEA
GO:0006412	Process	Translation	IEA
GO:0006413	Process	Translational initiation	IBA
GO:0006413	Process	Translational initiation	IEA
GO:0006417	Process	Regulation of translation	IEA
GO:0016281	Component	Eukaryotic translation initiation factor 4F complex	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

A6NMX2

Protein name

Eukaryotic translation initiation factor 4E type 1B

Protein function

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01652	IF4E	63 → 222	Eukaryotic initiation factor 4E	Domain

Sequence

MLAVEVSEAEGGIREWEEEEKEEEAAERTPTGEKSPNSPRTLLSLRGKARTGGPMEVKLE
LHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFK
DGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVN
IRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKF
VV

Sequence length

242

Interactions

View interactions

KEGG Pathway
EGFR tyrosine kinase inhibitor resistance
HIF-1 signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
Longevity regulating pathway
Insulin signaling pathway

EIF4E1B (eukaryotic translation initiation factor 4E family member 1B)

Save This Analysis