DYNLT3 (dynein light chain Tctex-type 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 6990 |
| Gene name | Dynein light chain Tctex-type 3 |
| Gene symbol | DYNLT3 |
| Synonyms (NCBI Gene) |
RP3TCTE1LTCTEX1L
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| Chromosome | X |
| Chromosome location | Xp11.4 |
| Summary | This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos inc |
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miRNA
miRNA information provided by mirtarbase database.
392
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P51808 | ||||||||||
| Protein name | Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like) | ||||||||||
| Protein function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor | ||||||||||
| Family and domains |
Pfam
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| Sequence | |||||||||||
| Sequence length | 116 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with DYNLT3 across shared curated disease and pathway associations.
5
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to DYNLT3 (see Related Genes above), that are NOT already directly curated for DYNLT3 itself -- a lead worth checking, not a confirmed association.
5
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