DEFB103B (defensin beta 103B) | GeDiPNet

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Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	55894
Gene name	Defensin beta 103B
Gene symbol	DEFB103B
Synonyms (NCBI Gene)	BD-3DEFB-3DEFB103DEFB3HBD-3HBD3HBP-3HBP3
Chromosome	8
Chromosome location	8p23.1
Summary	Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, which has broad spectrum antimicrobial activity and may play a

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IDA	21115716
GO:0005615	Component	Extracellular space	IEA
GO:0005796	Component	Golgi lumen	IEA
GO:0005796	Component	Golgi lumen	TAS
GO:0006952	Process	Defense response	IEA
GO:0031640	Process	Killing of cells of another organism	IDA	11085990, 15625724
GO:0031731	Function	CCR6 chemokine receptor binding	IBA
GO:0042056	Function	Chemoattractant activity	IBA
GO:0042742	Process	Defense response to bacterium	IBA
GO:0042742	Process	Defense response to bacterium	IEA
GO:0042742	Process	Defense response to bacterium	IMP	21115716
GO:0050829	Process	Defense response to Gram-negative bacterium	IDA	11085990, 15625724
GO:0050829	Process	Defense response to Gram-negative bacterium	IEA
GO:0050830	Process	Defense response to Gram-positive bacterium	IDA	15625724
GO:0050830	Process	Defense response to Gram-positive bacterium	IEA
GO:0050830	Process	Defense response to Gram-positive bacterium	IEP	11085990
GO:0050918	Process	Positive chemotaxis	IEA
GO:0051873	Process	Killing by host of symbiont cells	IDA	16436752
GO:0060326	Process	Cell chemotaxis	IBA
GO:0061844	Process	Antimicrobial humoral immune response mediated by antimicrobial peptide	IDA	11085990
GO:0140546	Process	Defense response to symbiont	IEA

MIM	HGNC	e!Ensembl
606611	31702	ENSG00000177243

Interactions View interactions

KEGG Pathway	Reactome Pathway
NOD-like receptor signaling pathway	Beta defensins
Staphylococcus aureus infection	Defensins