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Gene Gene information from NCBI Gene database.
Entrez ID 10671
Gene name Dynactin subunit 6
Gene symbol DCTN6
Synonyms (NCBI Gene)
WS-3WS3p27
Chromosome 8
Chromosome location 8p12
Summary The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has
miRNA miRNA information provided by mirtarbase database.
464 Show/Hide all (464)
miRTarBase ID miRNA Experiments Reference
MIRT027961 hsa-miR-93-5p Sequencing 20371350
MIRT711983 hsa-miR-2681-3p HITS-CLIP 19536157
MIRT711982 hsa-miR-4735-5p HITS-CLIP 19536157
MIRT711981 hsa-miR-6716-5p HITS-CLIP 19536157
MIRT704338 hsa-miR-224-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14 Show/Hide all (14)
GO ID Ontology Definition Evidence Reference
GO:0000775 Component Chromosome, centromeric region IEA
GO:0000776 Component Kinetochore IEA
GO:0005694 Component Chromosome IEA
GO:0005737 Component Cytoplasm IEA
GO:0005813 Component Centrosome IDA 21399614
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612963 16964 ENSG00000104671
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O00399
Protein name Dynactin subunit 6 (Dynactin subunit p27) (Protein WS-3)
Protein function Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
PDB 3TV0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00132 Hexapep 98 → 133 Bacterial transferase hexapeptide (six repeats) Repeat
Tissue specificity TISSUE SPECIFICITY: Ubiquitous.
Sequence
MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQA
LIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILT
SGCIIGACCNLNT
FEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKT
MKGSSTPVKN
Sequence length 190
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Motor proteins MHC class II antigen presentation
Vasopressin-regulated water reabsorption HSP90 chaperone cycle for steroid hormone receptors (SHR)
Amyotrophic lateral sclerosis COPI-mediated anterograde transport
Huntington disease COPI-independent Golgi-to-ER retrograde traffic
Pathways of neurodegeneration - multiple diseases  
Salmonella infection