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Gene Gene information from NCBI Gene database.
Entrez ID 57834
Gene name Cytochrome P450 family 4 subfamily F member 11
Gene symbol CYP4F11
Synonyms (NCBI Gene)
CYPIVF11
Chromosome 19
Chromosome location 19p13.12
Summary This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gen
miRNA miRNA information provided by mirtarbase database.
381 Show/Hide all (381)
miRTarBase ID miRNA Experiments Reference
MIRT028889 hsa-miR-26b-5p Microarray 19088304
MIRT719876 hsa-miR-6758-3p HITS-CLIP 19536157
MIRT719875 hsa-miR-7162-3p HITS-CLIP 19536157
MIRT719874 hsa-miR-4513 HITS-CLIP 19536157
MIRT719873 hsa-miR-6855-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0004497 Function Monooxygenase activity IEA
GO:0004497 Function Monooxygenase activity TAS
GO:0005504 Function Fatty acid binding IDA 18065749
GO:0005506 Function Iron ion binding IEA
GO:0005515 Function Protein binding IPI 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611517 13265 ENSG00000171903
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9HBI6
Protein name Cytochrome P450 4F11 (CYPIVF11) (EC 1.14.14.1) (3-hydroxy fatty acids omega-hydroxylase CYP4F11) (Docosahexaenoic acid omega-hydroxylase) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) (Phylloquinone omega-hydroxylase CYP4F11)
Protein function A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids and their oxygenated derivatives (oxylipins) (PubMed:15364545, PubMed:18065749, PubMed:24138531, PubMed:37373382). Mechanistically
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00067 p450 52 → 515 Cytochrome P450 Domain
Tissue specificity TISSUE SPECIFICITY: Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. {ECO:0000269|PubMed:10964514, ECO:0000269|PubMed:24138531}.
Sequence
Sequence length 524
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Fatty acids
Miscellaneous substrates
Eicosanoids
Synthesis of Leukotrienes (LT) and Eoxins (EX)