CACNG4 (calcium voltage-gated channel auxiliary subunit gamma 4)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 27092
• Gene name: Calcium voltage-gated channel auxiliary subunit gamma 4
• Gene symbol: CACNG4
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17q24.2
• Summary: The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the

miRNA Show/Hide all (354)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017598	hsa-miR-335-5p	Microarray	18185580
MIRT858086	hsa-miR-1	CLIP-seq
MIRT858087	hsa-miR-105	CLIP-seq
MIRT858088	hsa-miR-1243	CLIP-seq
MIRT858089	hsa-miR-1270	CLIP-seq
MIRT858090	hsa-miR-1273f	CLIP-seq
MIRT858091	hsa-miR-1286	CLIP-seq
MIRT858092	hsa-miR-1289	CLIP-seq
MIRT858093	hsa-miR-1291	CLIP-seq
MIRT858094	hsa-miR-1321	CLIP-seq
MIRT858095	hsa-miR-149	CLIP-seq
MIRT858096	hsa-miR-1587	CLIP-seq
MIRT858097	hsa-miR-1827	CLIP-seq
MIRT858098	hsa-miR-185	CLIP-seq
MIRT858099	hsa-miR-1915	CLIP-seq
MIRT858100	hsa-miR-206	CLIP-seq
MIRT858101	hsa-miR-208a	CLIP-seq
MIRT858102	hsa-miR-208b	CLIP-seq
MIRT858103	hsa-miR-2277-3p	CLIP-seq
MIRT858104	hsa-miR-2355-5p	CLIP-seq
MIRT858105	hsa-miR-24	CLIP-seq
MIRT858106	hsa-miR-29a	CLIP-seq
MIRT858107	hsa-miR-29b	CLIP-seq
MIRT858108	hsa-miR-29c	CLIP-seq
MIRT858109	hsa-miR-300	CLIP-seq
MIRT858110	hsa-miR-3064-5p	CLIP-seq
MIRT858111	hsa-miR-3125	CLIP-seq
MIRT858112	hsa-miR-3151	CLIP-seq
MIRT858113	hsa-miR-3165	CLIP-seq
MIRT858114	hsa-miR-3180	CLIP-seq
MIRT858115	hsa-miR-3180-3p	CLIP-seq
MIRT858116	hsa-miR-3196	CLIP-seq
MIRT858117	hsa-miR-3198	CLIP-seq
MIRT858118	hsa-miR-3202	CLIP-seq
MIRT858119	hsa-miR-320e	CLIP-seq
MIRT858120	hsa-miR-330-3p	CLIP-seq
MIRT858121	hsa-miR-3612	CLIP-seq
MIRT858122	hsa-miR-3613-3p	CLIP-seq
MIRT858123	hsa-miR-3617	CLIP-seq
MIRT858124	hsa-miR-3621	CLIP-seq
MIRT858125	hsa-miR-3646	CLIP-seq
MIRT858126	hsa-miR-3654	CLIP-seq
MIRT858127	hsa-miR-3673	CLIP-seq
MIRT858128	hsa-miR-3689d	CLIP-seq
MIRT858129	hsa-miR-371-5p	CLIP-seq
MIRT858130	hsa-miR-371b-5p	CLIP-seq
MIRT858131	hsa-miR-381	CLIP-seq
MIRT858132	hsa-miR-382	CLIP-seq
MIRT858133	hsa-miR-3914	CLIP-seq
MIRT858134	hsa-miR-3916	CLIP-seq
MIRT858135	hsa-miR-3926	CLIP-seq
MIRT858136	hsa-miR-3928	CLIP-seq
MIRT858137	hsa-miR-4265	CLIP-seq
MIRT858138	hsa-miR-4270	CLIP-seq
MIRT858139	hsa-miR-4284	CLIP-seq
MIRT858140	hsa-miR-4294	CLIP-seq
MIRT858141	hsa-miR-4296	CLIP-seq
MIRT858142	hsa-miR-4306	CLIP-seq
MIRT858143	hsa-miR-4307	CLIP-seq
MIRT858144	hsa-miR-4309	CLIP-seq
MIRT858145	hsa-miR-4314	CLIP-seq
MIRT858146	hsa-miR-432	CLIP-seq
MIRT858147	hsa-miR-4322	CLIP-seq
MIRT858148	hsa-miR-4419a	CLIP-seq
MIRT858149	hsa-miR-4433	CLIP-seq
MIRT858150	hsa-miR-4441	CLIP-seq
MIRT858151	hsa-miR-4443	CLIP-seq
MIRT858152	hsa-miR-4446-3p	CLIP-seq
MIRT858153	hsa-miR-4447	CLIP-seq
MIRT858154	hsa-miR-4468	CLIP-seq
MIRT858155	hsa-miR-4472	CLIP-seq
MIRT858156	hsa-miR-4476	CLIP-seq
MIRT858157	hsa-miR-4488	CLIP-seq
MIRT858158	hsa-miR-4492	CLIP-seq
MIRT858159	hsa-miR-4498	CLIP-seq
MIRT858160	hsa-miR-4510	CLIP-seq
MIRT858161	hsa-miR-4531	CLIP-seq
MIRT858162	hsa-miR-4534	CLIP-seq
MIRT858163	hsa-miR-4640-5p	CLIP-seq
MIRT858164	hsa-miR-4644	CLIP-seq
MIRT858165	hsa-miR-4649-3p	CLIP-seq
MIRT858166	hsa-miR-4656	CLIP-seq
MIRT858167	hsa-miR-4666-3p	CLIP-seq
MIRT858168	hsa-miR-4667-5p	CLIP-seq
MIRT858169	hsa-miR-4670-3p	CLIP-seq
MIRT858170	hsa-miR-4675	CLIP-seq
MIRT858171	hsa-miR-4677-3p	CLIP-seq
MIRT858172	hsa-miR-4685-5p	CLIP-seq
MIRT858173	hsa-miR-4697-5p	CLIP-seq
MIRT858174	hsa-miR-4700-5p	CLIP-seq
MIRT858175	hsa-miR-4715-5p	CLIP-seq
MIRT858176	hsa-miR-4720-3p	CLIP-seq
MIRT858177	hsa-miR-4721	CLIP-seq
MIRT858178	hsa-miR-4722-5p	CLIP-seq
MIRT858179	hsa-miR-4726-3p	CLIP-seq
MIRT858180	hsa-miR-4726-5p	CLIP-seq
MIRT858181	hsa-miR-4728-5p	CLIP-seq
MIRT858182	hsa-miR-4730	CLIP-seq
MIRT858183	hsa-miR-4739	CLIP-seq
MIRT858184	hsa-miR-4741	CLIP-seq
MIRT858185	hsa-miR-4753-5p	CLIP-seq
MIRT858186	hsa-miR-4756-5p	CLIP-seq
MIRT858187	hsa-miR-4779	CLIP-seq
MIRT858188	hsa-miR-4789-5p	CLIP-seq
MIRT858189	hsa-miR-4794	CLIP-seq
MIRT858190	hsa-miR-4804-3p	CLIP-seq
MIRT858191	hsa-miR-486-3p	CLIP-seq
MIRT858192	hsa-miR-491-5p	CLIP-seq
MIRT858193	hsa-miR-493	CLIP-seq
MIRT858194	hsa-miR-499-5p	CLIP-seq
MIRT858195	hsa-miR-513a-5p	CLIP-seq
MIRT858196	hsa-miR-516b	CLIP-seq
MIRT858197	hsa-miR-548ag	CLIP-seq
MIRT858198	hsa-miR-548ai	CLIP-seq
MIRT858199	hsa-miR-552	CLIP-seq
MIRT858200	hsa-miR-582-3p	CLIP-seq
MIRT858201	hsa-miR-583	CLIP-seq
MIRT858202	hsa-miR-604	CLIP-seq
MIRT858203	hsa-miR-613	CLIP-seq
MIRT858204	hsa-miR-620	CLIP-seq
MIRT858205	hsa-miR-637	CLIP-seq
MIRT858206	hsa-miR-641	CLIP-seq
MIRT858207	hsa-miR-646	CLIP-seq
MIRT858208	hsa-miR-647	CLIP-seq
MIRT858209	hsa-miR-650	CLIP-seq
MIRT858210	hsa-miR-762	CLIP-seq
MIRT858211	hsa-miR-764	CLIP-seq
MIRT858212	hsa-miR-765	CLIP-seq
MIRT858213	hsa-miR-873	CLIP-seq
MIRT858214	hsa-miR-876-3p	CLIP-seq
MIRT858215	hsa-miR-885-3p	CLIP-seq
MIRT858216	hsa-miR-924	CLIP-seq
MIRT1954838	hsa-miR-1262	CLIP-seq
MIRT858090	hsa-miR-1273f	CLIP-seq
MIRT858094	hsa-miR-1321	CLIP-seq
MIRT1954839	hsa-miR-143	CLIP-seq
MIRT858095	hsa-miR-149	CLIP-seq
MIRT858098	hsa-miR-185	CLIP-seq
MIRT1954840	hsa-miR-1972	CLIP-seq
MIRT858105	hsa-miR-24	CLIP-seq
MIRT858110	hsa-miR-3064-5p	CLIP-seq
MIRT858111	hsa-miR-3125	CLIP-seq
MIRT1954841	hsa-miR-3175	CLIP-seq
MIRT1954842	hsa-miR-3176	CLIP-seq
MIRT858114	hsa-miR-3180	CLIP-seq
MIRT858115	hsa-miR-3180-3p	CLIP-seq
MIRT858116	hsa-miR-3196	CLIP-seq
MIRT858118	hsa-miR-3202	CLIP-seq
MIRT1954843	hsa-miR-323-5p	CLIP-seq
MIRT1954844	hsa-miR-34a	CLIP-seq
MIRT1954845	hsa-miR-34c-5p	CLIP-seq
MIRT858124	hsa-miR-3621	CLIP-seq
MIRT1954846	hsa-miR-3658	CLIP-seq
MIRT858128	hsa-miR-3689d	CLIP-seq
MIRT858134	hsa-miR-3916	CLIP-seq
MIRT1954847	hsa-miR-3920	CLIP-seq
MIRT1954848	hsa-miR-3922-3p	CLIP-seq
MIRT858136	hsa-miR-3928	CLIP-seq
MIRT1954849	hsa-miR-4251	CLIP-seq
MIRT858139	hsa-miR-4284	CLIP-seq
MIRT858142	hsa-miR-4306	CLIP-seq
MIRT858145	hsa-miR-4314	CLIP-seq
MIRT1954850	hsa-miR-4329	CLIP-seq
MIRT858148	hsa-miR-4419a	CLIP-seq
MIRT858152	hsa-miR-4446-3p	CLIP-seq
MIRT858153	hsa-miR-4447	CLIP-seq
MIRT1954851	hsa-miR-4455	CLIP-seq
MIRT858155	hsa-miR-4472	CLIP-seq
MIRT858156	hsa-miR-4476	CLIP-seq
MIRT858157	hsa-miR-4488	CLIP-seq
MIRT858158	hsa-miR-4492	CLIP-seq
MIRT858159	hsa-miR-4498	CLIP-seq
MIRT1954852	hsa-miR-449a	CLIP-seq
MIRT1954853	hsa-miR-449b	CLIP-seq
MIRT858160	hsa-miR-4510	CLIP-seq
MIRT1954854	hsa-miR-4527	CLIP-seq
MIRT858162	hsa-miR-4534	CLIP-seq
MIRT858163	hsa-miR-4640-5p	CLIP-seq
MIRT858164	hsa-miR-4644	CLIP-seq
MIRT1954855	hsa-miR-4649-5p	CLIP-seq
MIRT1954856	hsa-miR-4651	CLIP-seq
MIRT858168	hsa-miR-4667-5p	CLIP-seq
MIRT858173	hsa-miR-4697-5p	CLIP-seq
MIRT858174	hsa-miR-4700-5p	CLIP-seq
MIRT1954857	hsa-miR-4701-3p	CLIP-seq
MIRT1954858	hsa-miR-4708-5p	CLIP-seq
MIRT1954859	hsa-miR-4716-5p	CLIP-seq
MIRT1954860	hsa-miR-4717-5p	CLIP-seq
MIRT858180	hsa-miR-4726-5p	CLIP-seq
MIRT858181	hsa-miR-4728-5p	CLIP-seq
MIRT858182	hsa-miR-4730	CLIP-seq
MIRT858183	hsa-miR-4739	CLIP-seq
MIRT858186	hsa-miR-4756-5p	CLIP-seq
MIRT1954861	hsa-miR-4770	CLIP-seq
MIRT1954862	hsa-miR-4773	CLIP-seq
MIRT858189	hsa-miR-4794	CLIP-seq
MIRT858191	hsa-miR-486-3p	CLIP-seq
MIRT1954863	hsa-miR-541	CLIP-seq
MIRT1954864	hsa-miR-542-3p	CLIP-seq
MIRT858201	hsa-miR-583	CLIP-seq
MIRT1954865	hsa-miR-608	CLIP-seq
MIRT1954866	hsa-miR-609	CLIP-seq
MIRT858205	hsa-miR-637	CLIP-seq
MIRT1954867	hsa-miR-654-5p	CLIP-seq
MIRT858210	hsa-miR-762	CLIP-seq
MIRT858215	hsa-miR-885-3p	CLIP-seq
MIRT858086	hsa-miR-1	CLIP-seq
MIRT2192371	hsa-miR-106a	CLIP-seq
MIRT2192372	hsa-miR-106b	CLIP-seq
MIRT2192373	hsa-miR-1185	CLIP-seq
MIRT2192374	hsa-miR-1207-3p	CLIP-seq
MIRT2192375	hsa-miR-1253	CLIP-seq
MIRT858089	hsa-miR-1270	CLIP-seq
MIRT858090	hsa-miR-1273f	CLIP-seq
MIRT858094	hsa-miR-1321	CLIP-seq
MIRT2192376	hsa-miR-136	CLIP-seq
MIRT858095	hsa-miR-149	CLIP-seq
MIRT2192377	hsa-miR-1538	CLIP-seq
MIRT2192378	hsa-miR-17	CLIP-seq
MIRT858098	hsa-miR-185	CLIP-seq
MIRT858099	hsa-miR-1915	CLIP-seq
MIRT2192379	hsa-miR-193a-5p	CLIP-seq
MIRT2192380	hsa-miR-204	CLIP-seq
MIRT858100	hsa-miR-206	CLIP-seq
MIRT858101	hsa-miR-208a	CLIP-seq
MIRT858102	hsa-miR-208b	CLIP-seq
MIRT2192381	hsa-miR-20a	CLIP-seq
MIRT2192382	hsa-miR-20b	CLIP-seq
MIRT2192383	hsa-miR-211	CLIP-seq
MIRT858105	hsa-miR-24	CLIP-seq
MIRT2192384	hsa-miR-302a	CLIP-seq
MIRT2192385	hsa-miR-302b	CLIP-seq
MIRT2192386	hsa-miR-302c	CLIP-seq
MIRT2192387	hsa-miR-302d	CLIP-seq
MIRT2192388	hsa-miR-302e	CLIP-seq
MIRT858110	hsa-miR-3064-5p	CLIP-seq
MIRT858111	hsa-miR-3125	CLIP-seq
MIRT2192389	hsa-miR-3155	CLIP-seq
MIRT2192390	hsa-miR-3155b	CLIP-seq
MIRT2192391	hsa-miR-3160-5p	CLIP-seq
MIRT1954841	hsa-miR-3175	CLIP-seq
MIRT2192392	hsa-miR-335	CLIP-seq
MIRT2192393	hsa-miR-34c-3p	CLIP-seq
MIRT2192394	hsa-miR-3614-3p	CLIP-seq
MIRT2192395	hsa-miR-3648	CLIP-seq
MIRT1954846	hsa-miR-3658	CLIP-seq
MIRT2192396	hsa-miR-3661	CLIP-seq
MIRT858127	hsa-miR-3673	CLIP-seq
MIRT2192397	hsa-miR-3679-5p	CLIP-seq
MIRT2192398	hsa-miR-3687	CLIP-seq
MIRT858128	hsa-miR-3689d	CLIP-seq
MIRT2192399	hsa-miR-372	CLIP-seq
MIRT2192400	hsa-miR-373	CLIP-seq
MIRT2192401	hsa-miR-3913-3p	CLIP-seq
MIRT858133	hsa-miR-3914	CLIP-seq
MIRT858134	hsa-miR-3916	CLIP-seq
MIRT1954847	hsa-miR-3920	CLIP-seq
MIRT2192402	hsa-miR-3929	CLIP-seq
MIRT1954849	hsa-miR-4251	CLIP-seq
MIRT2192403	hsa-miR-4252	CLIP-seq
MIRT858139	hsa-miR-4284	CLIP-seq
MIRT858142	hsa-miR-4306	CLIP-seq
MIRT858145	hsa-miR-4314	CLIP-seq
MIRT858148	hsa-miR-4419a	CLIP-seq
MIRT2192404	hsa-miR-4419b	CLIP-seq
MIRT2192405	hsa-miR-4434	CLIP-seq
MIRT2192406	hsa-miR-4442	CLIP-seq
MIRT2192407	hsa-miR-4478	CLIP-seq
MIRT2192408	hsa-miR-4493	CLIP-seq
MIRT858160	hsa-miR-4510	CLIP-seq
MIRT2192409	hsa-miR-4514	CLIP-seq
MIRT2192410	hsa-miR-4516	CLIP-seq
MIRT858161	hsa-miR-4531	CLIP-seq
MIRT858162	hsa-miR-4534	CLIP-seq
MIRT2192411	hsa-miR-4539	CLIP-seq
MIRT858163	hsa-miR-4640-5p	CLIP-seq
MIRT858164	hsa-miR-4644	CLIP-seq
MIRT2192412	hsa-miR-4645-5p	CLIP-seq
MIRT2192413	hsa-miR-4659a-3p	CLIP-seq
MIRT2192414	hsa-miR-4659b-3p	CLIP-seq
MIRT858168	hsa-miR-4667-5p	CLIP-seq
MIRT2192415	hsa-miR-4673	CLIP-seq
MIRT2192416	hsa-miR-4692	CLIP-seq
MIRT858174	hsa-miR-4700-5p	CLIP-seq
MIRT2192417	hsa-miR-4706	CLIP-seq
MIRT2192418	hsa-miR-4707-5p	CLIP-seq
MIRT2192419	hsa-miR-4714-5p	CLIP-seq
MIRT2192420	hsa-miR-4717-3p	CLIP-seq
MIRT858176	hsa-miR-4720-3p	CLIP-seq
MIRT858180	hsa-miR-4726-5p	CLIP-seq
MIRT858181	hsa-miR-4728-5p	CLIP-seq
MIRT858183	hsa-miR-4739	CLIP-seq
MIRT2192421	hsa-miR-4745-3p	CLIP-seq
MIRT2192422	hsa-miR-4749-5p	CLIP-seq
MIRT858186	hsa-miR-4756-5p	CLIP-seq
MIRT2192423	hsa-miR-4778-3p	CLIP-seq
MIRT858189	hsa-miR-4794	CLIP-seq
MIRT858190	hsa-miR-4804-3p	CLIP-seq
MIRT2192424	hsa-miR-484	CLIP-seq
MIRT858191	hsa-miR-486-3p	CLIP-seq
MIRT2192425	hsa-miR-489	CLIP-seq
MIRT2192426	hsa-miR-492	CLIP-seq
MIRT858194	hsa-miR-499-5p	CLIP-seq
MIRT2192427	hsa-miR-512-3p	CLIP-seq
MIRT858195	hsa-miR-513a-5p	CLIP-seq
MIRT2192428	hsa-miR-515-5p	CLIP-seq
MIRT858196	hsa-miR-516b	CLIP-seq
MIRT2192429	hsa-miR-519d	CLIP-seq
MIRT2192430	hsa-miR-520a-3p	CLIP-seq
MIRT2192431	hsa-miR-520b	CLIP-seq
MIRT2192432	hsa-miR-520c-3p	CLIP-seq
MIRT2192433	hsa-miR-520d-3p	CLIP-seq
MIRT2192434	hsa-miR-520e	CLIP-seq
MIRT2192435	hsa-miR-520g	CLIP-seq
MIRT2192436	hsa-miR-520h	CLIP-seq
MIRT1954864	hsa-miR-542-3p	CLIP-seq
MIRT858199	hsa-miR-552	CLIP-seq
MIRT2192437	hsa-miR-578	CLIP-seq
MIRT858200	hsa-miR-582-3p	CLIP-seq
MIRT858201	hsa-miR-583	CLIP-seq
MIRT858203	hsa-miR-613	CLIP-seq
MIRT858204	hsa-miR-620	CLIP-seq
MIRT2192438	hsa-miR-631	CLIP-seq
MIRT858205	hsa-miR-637	CLIP-seq
MIRT858207	hsa-miR-646	CLIP-seq
MIRT858211	hsa-miR-764	CLIP-seq
MIRT858213	hsa-miR-873	CLIP-seq
MIRT858215	hsa-miR-885-3p	CLIP-seq
MIRT2192439	hsa-miR-93	CLIP-seq
MIRT858097	hsa-miR-1827	CLIP-seq
MIRT2385469	hsa-miR-4316	CLIP-seq
MIRT2385470	hsa-miR-4682	CLIP-seq
MIRT2385471	hsa-miR-4765	CLIP-seq
MIRT858205	hsa-miR-637	CLIP-seq
MIRT858089	hsa-miR-1270	CLIP-seq
MIRT858098	hsa-miR-185	CLIP-seq
MIRT2192403	hsa-miR-4252	CLIP-seq
MIRT858142	hsa-miR-4306	CLIP-seq
MIRT858146	hsa-miR-432	CLIP-seq
MIRT858161	hsa-miR-4531	CLIP-seq
MIRT858164	hsa-miR-4644	CLIP-seq
MIRT1954860	hsa-miR-4717-5p	CLIP-seq
MIRT858204	hsa-miR-620	CLIP-seq
MIRT858216	hsa-miR-924	CLIP-seq
MIRT858089	hsa-miR-1270	CLIP-seq
MIRT858098	hsa-miR-185	CLIP-seq
MIRT2192403	hsa-miR-4252	CLIP-seq
MIRT858142	hsa-miR-4306	CLIP-seq
MIRT858146	hsa-miR-432	CLIP-seq
MIRT858161	hsa-miR-4531	CLIP-seq
MIRT858164	hsa-miR-4644	CLIP-seq
MIRT1954860	hsa-miR-4717-5p	CLIP-seq
MIRT858204	hsa-miR-620	CLIP-seq
MIRT858216	hsa-miR-924	CLIP-seq

Gene ontology (GO) Show/Hide all (32)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005245	Function	Voltage-gated calcium channel activity	IBA
GO:0005245	Function	Voltage-gated calcium channel activity	IEA
GO:0005246	Function	Calcium channel regulator activity	IDA	21127204
GO:0005262	Function	Calcium channel activity	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	10613843
GO:0005891	Component	Voltage-gated calcium channel complex	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006816	Process	Calcium ion transport	IEA
GO:0009986	Component	Cell surface	IEA
GO:0016020	Component	Membrane	IEA
GO:0016247	Function	Channel regulator activity	IBA
GO:0019226	Process	Transmission of nerve impulse	IBA
GO:0019226	Process	Transmission of nerve impulse	IEA
GO:0030666	Component	Endocytic vesicle membrane	TAS
GO:0032281	Component	AMPA glutamate receptor complex	IBA
GO:0032281	Component	AMPA glutamate receptor complex	IEA
GO:0032281	Component	AMPA glutamate receptor complex	ISS
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034702	Component	Monoatomic ion channel complex	IEA
GO:0035255	Function	Ionotropic glutamate receptor binding	IEA
GO:0036477	Component	Somatodendritic compartment	IEA
GO:0042220	Process	Response to cocaine	IEA
GO:0044297	Component	Cell body	IEA
GO:0051968	Process	Positive regulation of synaptic transmission, glutamatergic	IBA
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0098839	Component	Postsynaptic density membrane	IBA
GO:0098839	Component	Postsynaptic density membrane	IEA
GO:0098970	Process	Postsynaptic neurotransmitter receptor diffusion trapping	IBA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:1990454	Component	L-type voltage-gated calcium channel complex	IDA	21127204
GO:2000311	Process	Regulation of AMPA receptor activity	IDA	21172611

Other IDs

• MIM: 606404
• HGNC: 1408
• e!Ensembl: ENSG00000075461

Protein

• UniProt ID: Q9UBN1
• Protein name: Voltage-dependent calcium channel gamma-4 subunit (Neuronal voltage-gated calcium channel gamma-4 subunit) (Transmembrane AMPAR regulatory protein gamma-4) (TARP gamma-4)
• Protein function: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00822	PMP22_Claudin	6 → 202	PMP-22/EMP/MP20/Claudin family	Family

• Tissue specificity: TISSUE SPECIFICITY: Detected in heart left ventricle. {ECO:0000269|PubMed:21127204}.
• Sequence:

  MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD
  LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL
  GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN
  YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR
  RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF
  LQVHDFFQQDLKEGFHVSMLNRRTTPV

• Sequence length: 327

Pathways

KEGG Pathway	Reactome Pathway
MAPK signaling pathway	Presynaptic depolarization and calcium channel opening
Cardiac muscle contraction	Trafficking of AMPA receptors
Adrenergic signaling in cardiomyocytes	Phase 0 - rapid depolarisation
Oxytocin signaling pathway	Phase 2 - plateau phase
Hypertrophic cardiomyopathy	LGI-ADAM interactions
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (6)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
ASTROCYTOMA	—	GWAS catalog	36810956	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	21057379	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL OR BEHAVIOURAL DISORDER	—	GWAS catalog	21057379	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SAPHO SYNDROME	—	GWAS catalog	33816493	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	21057379	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	30019117	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Neoplasms	Breast neoplasm	Pubtator	37747033, 38291367	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	27602771	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	GWASCAT_DG	29594489		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	27102562		★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Related Genes

Sort by: Blended Diseases Pathways Evidence source

CACNG2 12 shared pathwaysMAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Phase 2 - plateau phase, Trafficking of AMPA receptors, Phase 0 - rapid depolarisation, LGI-ADAM interactions, Presynaptic depolarization and calcium channel opening Related via 12 shared pathways including MAPK signaling pathway, Cardiac muscle contraction. CACNG3 11 shared pathwaysMAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Phase 2 - plateau phase, Trafficking of AMPA receptors, Phase 0 - rapid depolarisation, LGI-ADAM interactions Related via 11 shared pathways including MAPK signaling pathway, Cardiac muscle contraction. CACNG8 11 shared pathwaysMAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Phase 2 - plateau phase, Trafficking of AMPA receptors, Phase 0 - rapid depolarisation, LGI-ADAM interactions Related via 11 shared pathways including MAPK signaling pathway, Cardiac muscle contraction. CACNA2D3 10 shared pathwaysMAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Phase 2 - plateau phase, Phase 0 - rapid depolarisation, Presynaptic depolarization and calcium channel opening Related via 10 shared pathways including MAPK signaling pathway, Cardiac muscle contraction. CACNA2D1 10 shared pathwaysMAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Phase 2 - plateau phase, Phase 0 - rapid depolarisation, Presynaptic depolarization and calcium channel opening Related via 10 shared pathways including MAPK signaling pathway, Cardiac muscle contraction.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
CACNG2	0	[]	12	["MAPK signaling pathway","Cardiac muscle contraction","Adrenergic signaling in cardiomyocytes","Oxytocin signaling pathway","Hypertrophic cardiomyopathy","Arrhythmogenic right ventricular cardiomyopathy","Dilated cardiomyopathy","Phase 2 - plateau phase","Trafficking of AMPA receptors","Phase 0 - rapid depolarisation","LGI-ADAM interactions","Presynaptic depolarization and calcium channel opening"]	0	[]
CACNG3	0	[]	11	["MAPK signaling pathway","Cardiac muscle contraction","Adrenergic signaling in cardiomyocytes","Oxytocin signaling pathway","Hypertrophic cardiomyopathy","Arrhythmogenic right ventricular cardiomyopathy","Dilated cardiomyopathy","Phase 2 - plateau phase","Trafficking of AMPA receptors","Phase 0 - rapid depolarisation","LGI-ADAM interactions"]	0	[]
CACNG8	0	[]	11	["MAPK signaling pathway","Cardiac muscle contraction","Adrenergic signaling in cardiomyocytes","Oxytocin signaling pathway","Hypertrophic cardiomyopathy","Arrhythmogenic right ventricular cardiomyopathy","Dilated cardiomyopathy","Phase 2 - plateau phase","Trafficking of AMPA receptors","Phase 0 - rapid depolarisation","LGI-ADAM interactions"]	0	[]
CACNA2D3	0	[]	10	["MAPK signaling pathway","Cardiac muscle contraction","Adrenergic signaling in cardiomyocytes","Oxytocin signaling pathway","Hypertrophic cardiomyopathy","Arrhythmogenic right ventricular cardiomyopathy","Dilated cardiomyopathy","Phase 2 - plateau phase","Phase 0 - rapid depolarisation","Presynaptic depolarization and calcium channel opening"]	0	[]
CACNA2D1	0	[]	10	["MAPK signaling pathway","Cardiac muscle contraction","Adrenergic signaling in cardiomyocytes","Oxytocin signaling pathway","Hypertrophic cardiomyopathy","Arrhythmogenic right ventricular cardiomyopathy","Dilated cardiomyopathy","Phase 2 - plateau phase","Phase 0 - rapid depolarisation","Presynaptic depolarization and calcium channel opening"]	0	[]

Diseases Linked via Similar Genes

Neurodevelopmental disorder Linked via 3 of 5 related genesCACNG2, CACNA2D3, CACNA2D1 Intellectual developmental disorder Linked via 2 of 5 related genesCACNG2, CACNA2D1 Asthma Linked via 2 of 5 related genesCACNG3, CACNA2D1 Prostate cancer Linked via 2 of 5 related genesCACNG3, CACNA2D1 Diabetes mellitus type 2 Linked via 2 of 5 related genesCACNG3, CACNA2D3

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Neurodevelopmental disorder	3	["CACNG2","CACNA2D3","CACNA2D1"]
Intellectual developmental disorder	2	["CACNG2","CACNA2D1"]
Asthma	2	["CACNG3","CACNA2D1"]
Prostate cancer	2	["CACNG3","CACNA2D1"]
Diabetes mellitus type 2	2	["CACNG3","CACNA2D3"]